Volume 3, Issue 5

May 2011
pp 455—563

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Editorials

RasGrf1 and Aging

Kelvin J. A. Davies, Henry Jay Forman,

https://doi.org/10.18632/aging.100331 pp 455

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Cdc14b: A New Player in Aging

Zhubo Wei, Pumin Zhang,

https://doi.org/10.18632/aging.100332 pp 456

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Discussions

The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism

Bjørn Quistorff, Niels Grunnet,

https://doi.org/10.18632/aging.100329 pp 457—460

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BRCA1 A-Complex fine tunes repair functions of BRCA1

Janelle L Harris, Kum Kum Khanna,

https://doi.org/10.18632/aging.100334 pp 461—463

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Reviews

Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective

Alessandra Valerio, Giuseppe D'Antona, Enzo Nisoli,

https://doi.org/10.18632/aging.100322 pp 464—478

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Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes

Elizabeth A. Yu, David R. Weaver,

https://doi.org/10.18632/aging.100323 pp 479—493

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The promise of human embryonic stem cells in aging-associated diseases

Odessa Yabut, Harold S. Bernstein,

https://doi.org/10.18632/aging.100328 pp 494—508

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Research Papers

Cockayne Syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo

Irina V. Kovtun, Kurt O. Johnson, Cynthia T. McMurray,

https://doi.org/10.18632/aging.100324 pp 509—514

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Mutations in the BRCT binding site of BRCA1 result in hyper-recombination

Seth M. Dever, Sarah E. Golding, Elizabeth Rosenberg, Bret R. Adams, Michael O. Idowu, John M. Quillin, Nicholas Valerie, Bo Xu, Lawrence F. Povirk, Kristoffer Valerie,

https://doi.org/10.18632/aging.100325 pp 515—532

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Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans

Edward P. Weiss, Dennis T. Villareal, Luigi Fontana, Dong-Ho Han, John O. Holloszy,

https://doi.org/10.18632/aging.100327 pp 533—542

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Research Perspectives

Interference between PARPs and SIRT1: a novel approach to healthy ageing?

Carles Cantó, Johan Auwerx,

https://doi.org/10.18632/aging.100326 pp 543—547

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Maternal diet, aging and diabetes meet at a chromatin loop

Susan E. Ozanne, Ionel Sandovici, Miguel Constância,

https://doi.org/10.18632/aging.100330 pp 548—554

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Embryonic anti-aging niche

Irina M. Conboy, Hanadie Yousef, Michael J. Conboy,

https://doi.org/10.18632/aging.100333 pp 555—563

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