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Page: 12345 of 5

• Research PaperVolume 15, Issue 6pp 2275-2292

  PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway

  Relevance score: 0.00

  Xingang Cui, Xiaoyang Liu, Peng Kong, Ting Du, Tao Li, Guihe Yang, Weimin Zhang, Xingzhi Jing, Wenchao Wang

  Keywords: PTEN inhibitor, cartilage endplate, Nrf-2, mitophagy, ferroptosis

  Published in Aging on March 24, 2023

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• Research PaperVolume 14, Issue 22pp 8914-8926

  Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model

  Relevance score: 0.00

  Kento Takaya, Tatsuyuki Ishii, Toru Asou, Kazuo Kishi

  Keywords: glutaminase inhibitor, human skin, senescent cell, aging, therapeutic agent

  Published in Aging on November 21, 2022

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• Research PaperVolume 13, Issue 6pp 8975-8988

  PARP inhibitors in breast and ovarian cancer with BRCA mutations: a meta-analysis of survival

  Relevance score: 0.00

  Fengping Shao, Yaoyun Duan, Yunhe Zhao, Yinguang Li, Jun Liu, Cai Zhang, Shanyang He

  Keywords: PARP inhibitor, BRCA mutation, breast cancer, ovarian cancer, efficacy

  Published in Aging on March 11, 2021

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• Research PaperVolume 13, Issue 1pp 163-180

  Identification of a novel and potent small molecule inhibitor of SRPK1: mechanism of dual inhibition of SRPK1 for the inhibition of cancer progression

  Relevance score: 0.00

  Anshuman Chandra, Hanumappa Ananda, Nagendra Singh, Imteyaz Qamar

  Keywords: splicing inhibitor, structure based drug design, flow cytometery, MTT assay, virtual screening

  Published in Aging on December 3, 2020

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• Research PaperVolume 12, Issue 22pp 22949-22974

  In vitro and in vivo efficacy of the novel oral proteasome inhibitor NNU546 in multiple myeloma

  Relevance score: 0.00

  Hui Zhou, Meng Lei, Wang Wang, Mengjie Guo, Jia Wang, Haoyang Zhang, Li Qiao, Huayun Feng, Zhaogang Liu, Lijuan Chen, Jianhao Hou, Xueyuan Wang, Chenxi Gu, Bo Zhao, Evgeny Izumchenko, Ye Yang, Yongqiang Zhu

  Keywords: proteasome inhibitor, multiple myeloma, oral drug, mechanism research

  Published in Aging on November 16, 2020

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• EditorialVolume 9, Issue 6pp 1475-1476

  BET-inhibitors as sensitizers for BH3-mimetics

  Relevance score: 0.00

  Chiaki Tsuge Ishida, Georg Karpel-Massler, Markus D. Siegelin

  Keywords: Bromodomain Extraterminal domain proteins inhibitors, BH3-mimetics, drug combination therapies, cell death, cancer

  Published in Aging on June 26, 2017

• EditorialVolume 7, Issue 12pp 1030-1031

  TOR-inhibitors as gero-suppressors

  Relevance score: 0.00

  Mikhail Nikiforov

  Keywords: mTOR, Rapamycin, mTOR inhibitors, gero-suppression

  Published in Aging on December 30, 2015

• Research PaperVolume 17, Issue 9pp 2392-2409

  Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice

  Relevance score: 0.00

  Takashi Ohira, Naoyuki Kawao, Yuya Mizukami, Kiyotaka Okada, Akihito Nishikawa, Hisatoshi Yamao, Ayaka Yamada, Hiroshi Kaji

  Keywords: plasminogen activator inhibitor-1, aging, sarcopenia, osteoporosis, sex

  Published in Aging on September 11, 2025

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• Research PaperVolume 17, Issue 4pp 982-993

  Impact of Factor Xa inhibitors on cardiovascular events in older patients with nonvalvular atrial fibrillation

  Relevance score: 0.00

  Masahiko Takahashi, Takeshi Morimoto, Ryu Tsushima, Yuya Sudo, Ai Sakamoto, Masahiro Sogo, Masatomo Ozaki, Keisuke Okawa

  Keywords: Factor Xa inhibitor, atrial fibrillation, older patient, cardiovascular events

  Published in Aging on April 10, 2025

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• Research PaperVolume 15, Issue 24pp 15025-15049

  The efficacy of immune checkpoint inhibitors is limited in elderly NSCLC: a retrospective efficacy study and meta-analysis

  Relevance score: 0.00

  Jiaxin Yin, Yuxiao Song, Yang Fu, Wang Jun, Jiazhuo Tang, Zhimin Zhang, Qibin Song, Bicheng Zhang

  Keywords: immune checkpoint inhibitors, non-small cell lung cancer, age, elderly, meta-analysis

  Published in Aging on December 19, 2023

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• Research PaperVolume 15, Issue 18pp 9479-9498

  Complement and coagulation cascades pathway-related signature as a predictor of immunotherapy in metastatic urothelial cancer

  Relevance score: 0.00

  Zheng Gong, Yuming He, Xiao Mi, Chengcheng Li, Xiaoran Sun, Guoqiang Wang, Leo Li, Yusheng Han, Chunwei Xu, Wenxian Wang, Shangli Cai, Liang Wang, Zhongyuan Liu

  Keywords: urothelial cancer, immune checkpoint inhibitor, complement and coagulation cascades, predictive biomarker

  Published in Aging on September 24, 2023

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• Research PaperVolume 15, Issue 17pp 8770-8781

  Prognostic value of lactate dehydrogenase in patients with uveal melanoma treated with immune checkpoint inhibition

  Relevance score: 0.00

  Xiaocui Liang, Shan Zhou, Zefeng Xiao

  Keywords: immune checkpoint inhibitors, uveal melanoma, lactate dehydrogenase, prognosis

  Published in Aging on September 5, 2023

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• Research PaperVolume 15, Issue 16pp 8204-8219

  PTPRD mutation is a prognostic biomarker for sensitivity to ICIs treatment in advanced non-small cell lung cancer

  Relevance score: 0.00

  Zhixuan Ren, Li Wang, Chaohui Leng

  Keywords: NSCLC, PTPRD, immune checkpoint inhibitors, nomogram, TCGA

  Published in Aging on August 18, 2023

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• Research PaperVolume 14, Issue 6pp 2868-2879

  TP53/BRAF mutation as an aid in predicting response to immune-checkpoint inhibitor across multiple cancer types

  Relevance score: 0.00

  Jia-Zheng Cao, Gao-Sheng Yao, Fei Liu, Yi-Ming Tang, Peng-Ju Li, Zi-Hao Feng, Jun-Hang Luo, Jin-Huan Wei

  Keywords: immune-checkpoint inhibitor therapies, TP53, BRAF, prognosis, precision medicine

  Published in Aging on March 27, 2022

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• Research PaperVolume 13, Issue 24pp 25920-25930

  LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells

  Relevance score: 0.00

  Jiangdong Xiang, Lina Zhou, Yinyan He, Sufang Wu

  Keywords: LDH-A, PARP inhibitors, BRCA1, ovarian cancer, proliferation

  Published in Aging on December 16, 2021

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• Research PaperVolume 13, Issue 15pp 19598-19613

  Computational research of mTORC1 inhibitor on cerebral ischemia-reperfusion injury

  Relevance score: 0.00

  Hui Li, Wenzhuo Yang, Zhenhua Wang, Xu Wang, Yulei Hao, Jianxin Xi, Han Lu, Zhishan Du, Jiachun Feng, Bao Zhang, Di Ma

  Keywords: cerebral ischemia/reperfusion injury (CIRI), the mammalian target of rapamycin (mTORC1), mTORC1 inhibitors, autophagy

  Published in Aging on August 3, 2021

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• Research PaperVolume 13, Issue 9pp 12748-12765

  The different hypoglycemic effects between East Asian and non-Asian type 2 diabetes patients when treated with SGLT-2 inhibitors as an add-on treatment for metformin: a systematic review and meta-analysis of randomized controlled trials

  Relevance score: 0.00

  Xianzhi Li, Qianping Zhang, Xiaojun Zhou, Siyi Guo, Shan Jiang, Yuhan Zhang, Ruzhen Zhang, Jianjun Dong, Lin Liao

  Keywords: SGLT-2 inhibitors, metformin, Asian, type 2 diabetes, randomized controlled trial, meta-analysis

  Published in Aging on May 11, 2021

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• Research PaperVolume 13, Issue 8pp 10853-10865

  Does taking an angiotensin inhibitor increase the risk for COVID-19? – a systematic review and meta-analysis

  Relevance score: 0.00

  Zheng Ma, Mei-Ping Wang, Lian Liu, Shuang Yu, Tian-Ran Wu, Lei Zhao, Ye-Ping Zhang, Hai-Feng Liang, Xin-Chun Yang

  Keywords: coronavirus disease 2019, COVID-19, angiotensin-converting enzyme 2, angiotensin converting enzyme inhibitors, angiotensin receptor blockers

  Published in Aging on April 22, 2021

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• Research PaperVolume 13, Issue 4pp 5804-5823

  Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture

  Relevance score: 0.00

  Yuxin Zhang, Shenji Lu, Shuai Fan, Lili Xu, Xin Jiang, Kexin Wang, Bin Cai

  Keywords: macrophage migration inhibitory factor, post-traumatic joint contracture, inflammation, fibroblasts, fibrosis

  Published in Aging on February 17, 2021

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• Research PaperVolume 12, Issue 24pp 25101-25119

  Could microtubule inhibitors be the best choice of therapy in gastric cancer with high immune activity: mutant DYNC1H1 as a biomarker

  Relevance score: 0.00

  Jin Bai, BoWen Yang, Ruichuan Shi, Xinye Shao, Yujing Yang, Fang Wang, Jiawen Xiao, Xiujuan Qu, Yunpeng Liu, Ye Zhang, Zhi Li

  Keywords: immune checkpoint blockade, microtubule inhibitors, mutation, DYNC1H1, gastric cancer

  Published in Aging on November 20, 2020

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