Volume 7, Issue 12

Antidepressants synergize with chemotherapy against cancer stem cells

Gerry Melino,

https://doi.org/10.18632/aging.100848 pp 1024—1025

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Fasting plus tyrosine kinase inhibitors in cancer

Irene Caffa, Valter D. Longo, Alessio Nencioni,

https://doi.org/10.18632/aging.100857 pp 1026—1027

PDF How to Cite Special Collection on Cancer Therapeutics

c-Fos importance for brain development

Fabiola N. Velazquez, Beatriz L. Caputto, François D. Boussin,

https://doi.org/10.18632/aging.100862 pp 1028—1029

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TOR-inhibitors as gero-suppressors

Mikhail Nikiforov,

https://doi.org/10.18632/aging.100869 pp 1030—1031

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The PTEN tumor suppressor gene and its role in lymphoma pathogenesis

Xiaoxiao Wang, Huiqiang Huang, Ken H. Young,

https://doi.org/10.18632/aging.100855 pp 1032—1049

View Abstract PDF Full-Text How to Cite Special Collection on Tumor Suppressors

DNA repair and aging: the impact of the p53 family

Sara Nicolai, Antonello Rossi, Nicola Di Daniele, Gerry Melino, Margherita Annicchiarico-Petruzzelli, Giuseppe Raschellà,

https://doi.org/10.18632/aging.100858 pp 1050—1065

View Abstract PDF Full-Text How to Cite

Telomere length is a prognostic biomarker in elderly advanced ovarian cancer patients: a multicenter GINECO study

Claire Falandry, Béatrice Horard, Amandine Bruyas, Eric Legouffe, Jacques Cretin, Jérôme Meunier, Jérôme Alexandre, Valérie Delecroix, Michel Fabbro, Marie-Noëlle Certain, Raymonde Maraval-Gaget, Eric Pujade-Lauraine, Eric Gilson, Gilles Freyer,

https://doi.org/10.18632/aging.100840 pp 1066—1074

View Abstract PDF Full-Text How to Cite Special Collection on Biomarkers

A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged

Senthil Kannan, Andrew Kossenkov, Raj K. Kurupati, Jason ZQ Xiang, Susan A. Doyle, Kenneth E. Schmader, Louise Schowe, Hildegund C. Ertl,

https://doi.org/10.18632/aging.100852 pp 1077—1085

View Abstract PDF Full-Text How to Cite

Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)

Dominik H. Pesta, Rachel J. Perry, Fitsum Guebre-Egziabher, Dongyan Zhang, Michael Jurczak, Antje Fischer-Rosinsky, Martin A. Daniels, Diana M. Willmes, Sanjay Bhanot, Stefan R. Bornstein, Felix Knauf, Varman T. Samuel, Gerald I. Shulman, Andreas L. Birkenfeld,

https://doi.org/10.18632/aging.100854 pp 1086—1093

View Abstract PDF Full-Text How to Cite

Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus

Ana Maria Marques Orellana, Andrea Rodrigues Vasconcelos, Jacqueline Alves Leite, Larissa de Sá Lima, Diana Zukas Andreotti, Carolina Demarchi Munhoz, Elisa Mitiko Kawamoto, Cristoforo Scavone,

https://doi.org/10.18632/aging.100853 pp 1094—1108

View Abstract PDF Full-Text How to Cite

RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity

Stewart Frankel, Jared Woods, Tahereh Ziafazeli, Blanka Rogina,

https://doi.org/10.18632/aging.100856 pp 1112—1128

View Abstract PDF Full-Text How to Cite

Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients

Steve Horvath, Beate R Ritz,

https://doi.org/10.18632/aging.100859 pp 1130—1142

View Abstract PDF Full-Text How to Cite Special Collection on Steve Horvath's Publications in Aging (Albany NY)

NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation

Hao Tang, Xiuqin Fan, Junyue Xing, Zhenyun Liu, Bin Jiang, Yali Dou, Myriam Gorospe, Wengong Wang,

https://doi.org/10.18632/aging.100860 pp 1143—1155

View Abstract PDF Full-Text How to Cite

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring

Steve Horvath, Chiara Pirazzini, Maria Giulia Bacalini, Davide Gentilini, Anna Maria Di Blasio, Massimo Delledonne, Daniela Mari, Beatrice Arosio, Daniela Monti, Giuseppe Passarino, Francesco De Rango, Patrizia D'Aquila, Cristina Giuliani, Elena Marasco, Sebastiano Collino, Patrick Descombes, Paolo Garagnani, Claudio Franceschi,

https://doi.org/10.18632/aging.100861 pp 1159—1170

View Abstract PDF Full-Text How to Cite Special Collection on Steve Horvath's Publications in Aging (Albany NY)

DNA repair in species with extreme lifespan differences

Sheila L MacRae, Matthew McKnight Croken, R.B Calder, Alexander Aliper, Brandon Milholland, Ryan R White, Alexander Zhavoronkov, Vadim N Gladyshev, Andrei Seluanov, Vera Gorbunova, Zhengdong D Zhang, Jan Vijg,

https://doi.org/10.18632/aging.100866 pp 1171—1182

View Abstract PDF Full-Text How to Cite

Knockout of Angiotensin AT₂ receptors accelerates healing but impairs quality

Mahya Faghih, Sayed M Hosseini, Barbara Smith, Amir Mehdi Ansari, Frank Lay, Ali Karim Ahmed, Tedashi Inagami, Guy P Marti, John W Harmon, Jeremy D Walston, Peter M Abadir,

https://doi.org/10.18632/aging.100868 pp 1185—1197

View Abstract PDF Full-Text How to Cite

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

Morgan E Levine, Ake T Lu, David A Bennett, Steve Horvath,

https://doi.org/10.18632/aging.100864 pp 1198—1211

View Abstract PDF Full-Text How to Cite Special Collection on Alzheimer's Disease

Survival of irradiated recipient mice after transplantation of bone marrow from young, old and “early aging” mice

Ian Guest, Zoran Ilic, Heidi Scrable, Stewart Sell,

https://doi.org/10.18632/aging.100867 pp 1212—1222

View Abstract PDF Full-Text How to Cite

Volume 7, Issue 12

Editorials

Antidepressants synergize with chemotherapy against cancer stem cells

Gerry Melino,

Fasting plus tyrosine kinase inhibitors in cancer

Irene Caffa, Valter D. Longo, Alessio Nencioni,

c-Fos importance for brain development

Fabiola N. Velazquez, Beatriz L. Caputto, François D. Boussin,

TOR-inhibitors as gero-suppressors

Mikhail Nikiforov,

Reviews

The PTEN tumor suppressor gene and its role in lymphoma pathogenesis

Xiaoxiao Wang, Huiqiang Huang, Ken H. Young,

DNA repair and aging: the impact of the p53 family

Sara Nicolai, Antonello Rossi, Nicola Di Daniele, Gerry Melino, Margherita Annicchiarico-Petruzzelli, Giuseppe Raschellà,

Research Papers

Telomere length is a prognostic biomarker in elderly advanced ovarian cancer patients: a multicenter GINECO study

Claire Falandry, Béatrice Horard, Amandine Bruyas, Eric Legouffe, Jacques Cretin, Jérôme Meunier, Jérôme Alexandre, Valérie Delecroix, Michel Fabbro, Marie-Noëlle Certain, Raymonde Maraval-Gaget, Eric Pujade-Lauraine, Eric Gilson, Gilles Freyer,

A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged

Senthil Kannan, Andrew Kossenkov, Raj K. Kurupati, Jason ZQ Xiang, Susan A. Doyle, Kenneth E. Schmader, Louise Schowe, Hildegund C. Ertl,

Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)

Dominik H. Pesta, Rachel J. Perry, Fitsum Guebre-Egziabher, Dongyan Zhang, Michael Jurczak, Antje Fischer-Rosinsky, Martin A. Daniels, Diana M. Willmes, Sanjay Bhanot, Stefan R. Bornstein, Felix Knauf, Varman T. Samuel, Gerald I. Shulman, Andreas L. Birkenfeld,

Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus

Ana Maria Marques Orellana, Andrea Rodrigues Vasconcelos, Jacqueline Alves Leite, Larissa de Sá Lima, Diana Zukas Andreotti, Carolina Demarchi Munhoz, Elisa Mitiko Kawamoto, Cristoforo Scavone,

RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity

Stewart Frankel, Jared Woods, Tahereh Ziafazeli, Blanka Rogina,

Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients

Steve Horvath, Beate R Ritz,

NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation

Hao Tang, Xiuqin Fan, Junyue Xing, Zhenyun Liu, Bin Jiang, Yali Dou, Myriam Gorospe, Wengong Wang,

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring

DNA repair in species with extreme lifespan differences

Sheila L MacRae, Matthew McKnight Croken, R.B Calder, Alexander Aliper, Brandon Milholland, Ryan R White, Alexander Zhavoronkov, Vadim N Gladyshev, Andrei Seluanov, Vera Gorbunova, Zhengdong D Zhang, Jan Vijg,

Knockout of Angiotensin AT₂ receptors accelerates healing but impairs quality

Mahya Faghih, Sayed M Hosseini, Barbara Smith, Amir Mehdi Ansari, Frank Lay, Ali Karim Ahmed, Tedashi Inagami, Guy P Marti, John W Harmon, Jeremy D Walston, Peter M Abadir,

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

Morgan E Levine, Ake T Lu, David A Bennett, Steve Horvath,

Survival of irradiated recipient mice after transplantation of bone marrow from young, old and “early aging” mice

Ian Guest, Zoran Ilic, Heidi Scrable, Stewart Sell,

Table of Contents

Volume 7, Issue 12

Editorials

Gerry Melino,

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Irene Caffa, Valter D. Longo, Alessio Nencioni,

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Fabiola N. Velazquez, Beatriz L. Caputto, François D. Boussin,

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Mikhail Nikiforov,

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Reviews

Xiaoxiao Wang, Huiqiang Huang, Ken H. Young,

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Sara Nicolai, Antonello Rossi, Nicola Di Daniele, Gerry Melino, Margherita Annicchiarico-Petruzzelli, Giuseppe Raschellà,

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Research Papers

Claire Falandry, Béatrice Horard, Amandine Bruyas, Eric Legouffe, Jacques Cretin, Jérôme Meunier, Jérôme Alexandre, Valérie Delecroix, Michel Fabbro, Marie-Noëlle Certain, Raymonde Maraval-Gaget, Eric Pujade-Lauraine, Eric Gilson, Gilles Freyer,

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Senthil Kannan, Andrew Kossenkov, Raj K. Kurupati, Jason ZQ Xiang, Susan A. Doyle, Kenneth E. Schmader, Louise Schowe, Hildegund C. Ertl,

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Dominik H. Pesta, Rachel J. Perry, Fitsum Guebre-Egziabher, Dongyan Zhang, Michael Jurczak, Antje Fischer-Rosinsky, Martin A. Daniels, Diana M. Willmes, Sanjay Bhanot, Stefan R. Bornstein, Felix Knauf, Varman T. Samuel, Gerald I. Shulman, Andreas L. Birkenfeld,

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Ana Maria Marques Orellana, Andrea Rodrigues Vasconcelos, Jacqueline Alves Leite, Larissa de Sá Lima, Diana Zukas Andreotti, Carolina Demarchi Munhoz, Elisa Mitiko Kawamoto, Cristoforo Scavone,

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Stewart Frankel, Jared Woods, Tahereh Ziafazeli, Blanka Rogina,

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Steve Horvath, Beate R Ritz,

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Hao Tang, Xiuqin Fan, Junyue Xing, Zhenyun Liu, Bin Jiang, Yali Dou, Myriam Gorospe, Wengong Wang,

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Sheila L MacRae, Matthew McKnight Croken, R.B Calder, Alexander Aliper, Brandon Milholland, Ryan R White, Alexander Zhavoronkov, Vadim N Gladyshev, Andrei Seluanov, Vera Gorbunova, Zhengdong D Zhang, Jan Vijg,

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Mahya Faghih, Sayed M Hosseini, Barbara Smith, Amir Mehdi Ansari, Frank Lay, Ali Karim Ahmed, Tedashi Inagami, Guy P Marti, John W Harmon, Jeremy D Walston, Peter M Abadir,

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Morgan E Levine, Ake T Lu, David A Bennett, Steve Horvath,

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Ian Guest, Zoran Ilic, Heidi Scrable, Stewart Sell,

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Table of Contents