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• Research PaperVolume 14, Issue 23pp 9466-9483

  Identification of natural products and FDA-approved drugs for targeting cancer stem cell (CSC) propagation

  Relevance score: 0.00

  Gloria Bonuccelli, Federica Sotgia, Michael P. Lisanti

  Keywords: cancer stem cells, drug screening, natural compounds, FDA approved drugs, mammospheres

  Published in Aging on December 1, 2022

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• Research PaperVolume 16, Issue 4pp 4033-4051

  LGALS3BP is a novel and potential biomarker in clear cell renal cell carcinoma

  Relevance score: 0.00

  Lei Li, Sen Qin, Hongwei Tan, Jiexue Zhou

  Keywords: bioinformatics, biomarkers, LGALS3BP, clear cell renal cell carcinoma, drug screening

  Published in Aging on February 22, 2024

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• Research PaperVolume 15, Issue 14pp 7219-7236

  Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma

  Relevance score: 0.00

  Sen Qin, Lei Li, Da Liu

  Keywords: metastasis-related gene, immunity, osteosarcoma, immunotherapy, drug screening

  Published in Aging on July 25, 2023

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• Research PaperVolume 14, Issue 3pp 1448-1472

  Screening of antibacterial compounds with novel structure from the FDA approved drugs using machine learning methods

  Relevance score: 0.00

  Wen-Xing Li, Xin Tong, Peng-Peng Yang, Yang Zheng, Ji-Hao Liang, Gong-Hua Li, Dahai Liu, Dao-Gang Guan, Shao-Xing Dai

  Keywords: antibacterial compound, drug repositioning, machine learning, structural similarity, virtual screening

  Published in Aging on February 12, 2022

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• Research PaperVolume 8, Issue 9pp 2127-2152

  In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state

  Relevance score: 0.00

  Alexander Aliper, Aleksey V. Belikov, Andrew Garazha, Leslie Jellen, Artem Artemov, Maria Suntsova, Alena Ivanova, Larisa Venkova, Nicolas Borisov, Anton Buzdin, Polina Mamoshina, Evgeny Putin, Andrew G. Swick, Alexey Moskalev, Alex Zhavoronkov

  Keywords: geroprotector, drug discovery, screening, drug repurposing, aging

  Published in Aging on September 24, 2016

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• Research PaperVolume 13, Issue 20pp 23702-23725

  Selected ideal natural ligand against TNBC by inhibiting CDC20, using bioinformatics and molecular biology

  Relevance score: 0.00

  Naimeng Liu, Xinhui Wang, Zhu Zhu, Duo Li, Xiaye Lv, Yichang Chen, Haoqun Xie, Zhen Guo, Dong Song

  Keywords: CDC20, drug development, virtual screening, TNBC, targeted therapy

  Published in Aging on October 22, 2021

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• Research PaperVolume 13, Issue 19pp 22867-22882

  Computational study of effective matrix metalloproteinase 9 (MMP9) targeting natural inhibitors

  Relevance score: 0.00

  Naimeng Liu, Xinhui Wang, Hao Wu, Xiaye Lv, Haoqun Xie, Zhen Guo, Jing Wang, Gaojing Dou, Chenxi Zhang, Mindan Sun

  Keywords: MMP9, drug development, virtual screening, CCRCC, targeted therapy

  Published in Aging on October 4, 2021

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• Research PaperVolume 13, Issue 16pp 20246-20257

  Identification of effective natural PIK3CA H1047R inhibitors by computational study

  Relevance score: 0.00

  Naimeng Liu, Xinhui Wang, Xuan Li, Xiaye Lv, Haoqun Xie, Zhen Guo, Jing Wang, Gaojing Dou, Ye Du, Dong Song

  Keywords: PIK3CA H1047R, drug development, virtual screening, TNBC, targeted therapy

  Published in Aging on August 20, 2021

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• Research PaperVolume 13, Issue 2pp 1898-1912

  Effective natural inhibitors targeting poly ADP-ribose polymerase by computational study

  Relevance score: 0.00

  Sheng Zhong, Bo Wu, Wenzhuo Yang, Junliang Ge, Xiangheng Zhang, Zhenghe Chen, Hao Duan, Zhenqiang He, Yibing Liu, Hongyu Wang, Yuting Jiang, Zhiyun Zhang, Xinhui Wang, Weihang Li, Naimeng Liu, Xiaoyu Guo, Yonggao Mou

  Keywords: glioblastoma, PARP, natural products, drug treatment, virtual screening

  Published in Aging on January 23, 2021

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• Research PaperVolume 13, Issue 1pp 163-180

  Identification of a novel and potent small molecule inhibitor of SRPK1: mechanism of dual inhibition of SRPK1 for the inhibition of cancer progression

  Relevance score: 0.00

  Anshuman Chandra, Hanumappa Ananda, Nagendra Singh, Imteyaz Qamar

  Keywords: splicing inhibitor, structure based drug design, flow cytometery, MTT assay, virtual screening

  Published in Aging on December 3, 2020

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• Research PaperVolume 14, Issue 11pp 4874-4887

  Effective natural inhibitors targeting IGF-1R by computational study

  Relevance score: 0.00

  Xinyu Wang, Pengcheng Zhou, Liangxin Lin, Bo Wu, Zhaoyu Fu, Xing Huang, Dong Zhu

  Keywords: Ewing sarcoma, IGF-1R, drug therapy, natural compounds, virtual screening

  Published in Aging on June 9, 2022

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• Research PaperVolume 16, Issue 1pp 627-647

  Targeting of FSP1 regulates iron homeostasis in drug-tolerant persister head and neck cancer cells via lipid-metabolism-driven ferroptosis

  Relevance score: 0.00

  Yang-Che Wu, Chin-Sheng Huang, Ming-Shou Hsieh, Chih-Ming Huang, Syahru Agung Setiawan, Chi-Tai Yeh, Kuang-Tai Kuo, Shao-Cheng Liu

  Keywords: drug-tolerant persister cancer cells, tumor organoids, ferroptosis, FSP1

  Published in Aging on January 10, 2024

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• Research PaperVolume 15, Issue 24pp 14996-15024

  ATRX is a predictive marker for endocrinotherapy and chemotherapy resistance in HER2-/HR+ breast cancer through the regulation of the AR, GLI3 and GATA2 transcriptional network

  Relevance score: 0.00

  Hongyan Qian, Rui Ji, Cheng Shen, Yinze Wei, Chenyi Sheng, Qichao Ni, Jing Pan, Yifan Chi, Huan You, Ying Miao, Minxin Shi, Xianghua Huang, Aiguo Shen

  Keywords: ATRX, drug resistance, biomarker, breast cancer, transcription factor

  Published in Aging on December 20, 2023

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• Research PaperVolume 14, Issue 17pp 7038-7051

  The downregulated drug-metabolism related ALDH6A1 serves as predictor for prognosis and therapeutic immune response in gastric cancer

  Relevance score: 0.00

  Yuan Cai, Rong Zeng, Jinwu Peng, Wei Liu, Qingchun He, Zhijie Xu, Ning Bai

  Keywords: ALDH6A1, gastric cancer, drug-metabolism, prognosis, immune regulation

  Published in Aging on September 12, 2022

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• Research PaperVolume 12, Issue 22pp 22700-22718

  Drug-selected population in melanoma A2058 cells as melanoma stem-like cells retained angiogenic features – the potential roles of heparan-sulfate binding ANGPTL4 protein

  Relevance score: 0.00

  Chia-Yu Shih, Yu-Che Cheng, ChiaoHui Hsieh, TingTing Tseng, ShihSheng Jiang, Shao-Chen Lee

  Keywords: drug resistance, melanoma stem-like cells, angiopoietin-like 4 protein

  Published in Aging on November 10, 2020

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• Research PaperVolume 12, Issue 19pp 19711-19739

  Risk of hospitalization from drug-drug interactions in the Elderly: real-world evidence in a large administrative database

  Relevance score: 0.00

  Floor Swart, Giampaolo Bianchi, Jacopo Lenzi, Marica Iommi, Lorenzo Maestri, Emanuel Raschi, Marco Zoli, Fabrizio De Ponti, Elisabetta Poluzzi

  Keywords: drug-drug interactions, adverse drug reactions, elderly, case-control study, real-world evidence

  Published in Aging on October 5, 2020

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• Research PaperVolume 10, Issue 11pp 3294-3307

  Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

  Relevance score: 0.00

  Bela Ozsvari, John R. Nuttall, Federica Sotgia, Michael P. Lisanti

  Keywords: drug repurposing, aging, senescence, senolytic drugs, antibiotics, azithromycin, roxithromycin

  Published in Aging on November 14, 2018

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• EditorialVolume 15, Issue 12pp 5232-5234

  Advances in cancer therapy: clinical benefit of new cancer drugs

  Relevance score: 0.00

  Daniel Tobias Michaeli, Julia Caroline Michaeli, Thomas Michaeli

  Keywords: cancer drug, clinical benefit, overall survival, progression-free survival, clinical trial

  Published in Aging on June 19, 2023

• Research PaperVolume 13, Issue 12pp 16316-16340

  Comprehensive signature analysis of drug metabolism differences in the White, Black and Asian prostate cancer patients

  Relevance score: 0.00

  Yang Liu, Jia-Wei Zhou, Cun-Dong Liu, Jian-Kun Yang, De-Ying Liao, Zhi-Jian Liang, Xiao Xie, Qi-Zhao Zhou, Kang-Yi Xue, Wen-Bing Guo, Ming Xia, Jun-Hao Zhou, Ji-Ming Bao, Cheng Yang, Hai-Feng Duan, Hong-Yi Wang, Zhi-Peng Huang, Shan-Chao Zhao, Ming-Kun Chen

  Keywords: prostate cancer, race, drug resistance, drug metabolism, comprehensive signature

  Published in Aging on June 18, 2021

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• Research PaperVolume 13, Issue 6pp 8620-8627

  The whole term efficacy of different treatments in paroxysmal atrial fibrillation in aging: a meta-analysis of randomized controlled trials

  Relevance score: 0.00

  Yinan Sun, Lu Wang, Xiaoyun Yang

  Keywords: paroxysmal atrial fibrillation, catheter ablation, antiarrhythmic drug, quality of life

  Published in Aging on March 10, 2021

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