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• Research PaperVolume 12, Issue 23pp 23525-23547

  Mutation in histone deacetylase HDA-3 leads to shortened locomotor healthspan in Caenorhabditis elegans

  Relevance score: 0.00

  Kazuto Kawamura, Ichiro N. Maruyama

  Keywords: hda-3, age-related locomotor impairment, BATH domain, aging, longevity

  Published in Aging on December 3, 2020

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• Research PaperVolume 16, Issue 20pp 13132-13144

  OSBPL2 inhibition leads to apoptosis of cochlea hair cells in age-related hearing loss by inhibiting the AKT/FOXG1 signaling pathway

  Relevance score: 0.00

  Meina Li-Yang, Chao Ma, Xiaoye Wang, Jianqiang You

  Keywords: age-related hearing loss, OSBPL2, FOXG1, AKT, cochlea hair cells

  Published in Aging on October 30, 2024

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• Research PaperVolume 16, Issue 9pp 8044-8069

  Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

  Relevance score: 0.00

  Shan Luo, Qiang Hu, Bo Jiang, Zhongyu Zhang, Dawei Sun

  Keywords: age-related macular degeneration, cellular senescence, programmed cell death, inflammatory response, molecular subtypes

  Published in Aging on May 10, 2024

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• Research PaperVolume 15, Issue 20pp 10856-10874

  Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes

  Relevance score: 0.00

  María Marchante, Noelia Ramirez-Martin, Anna Buigues, Jessica Martinez, Nuria Pellicer, Antonio Pellicer, Sonia Herraiz

  Keywords: age-related infertility, ovarian aging, mouse model, oocyte quality, embryo development, mitochondrial function

  Published in Aging on October 16, 2023

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• Research PaperVolume 15, Issue 10pp 4498-4509

  Expression of αA-crystallin (CRYAA) in vivo and in vitro models of age-related cataract and the effect of its silencing on HLEB3 cells

  Relevance score: 0.00

  Xiaoling Ma, Yi Nan, Can Huang, Xiangyang Li, Yifan Yang, Wenjie Jiang, Mengyi Ye, Qian Liu, Yang Niu, Ling Yuan

  Keywords: age-related cataract, CRYAA

  Published in Aging on May 28, 2023

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• Research PaperVolume 15, Issue 6pp 1713-1733

  Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

  Relevance score: 0.00

  Tu Nguyen, Daniel Urrutia-Cabrera, Luozixian Wang, Jarmon G. Lees, Jiang-Hui Wang, Sandy S.C. Hung, Alex W. Hewitt, Thomas L. Edwards, Sam McLenachan, Fred K. Chen, Shiang Y. Lim, Chi D. Luu, Robyn Guymer, Raymond C.B. Wong

  Keywords: age-related macular degeneration, retina, CRISPR/Cas, mitochondria superoxide, POLDIP2

  Published in Aging on February 16, 2023

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• Research PaperVolume 15, Issue 1pp 37-52

  Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

  Relevance score: 0.00

  Chi-Hsiu Liu, Felix Yemanyi, Kiran Bora, Neetu Kushwah, Alexandra K. Blomfield, Theodore M. Kamenecka, John Paul SanGiovanni, Ye Sun, Laura A. Solt, Jing Chen

  Keywords: age-related macular degeneration, angiogenesis, choroidal neovascularization, inflammation, nuclear receptors, RORα, VEGFR2, TNFα

  Published in Aging on January 10, 2023

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• Research PaperVolume 13, Issue 24pp 25763-25777

  Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

  Relevance score: 0.00

  Charlotte Liisborg, Vibe Skov, Lasse Kjær, Hans Carl Hasselbalch, Torben Lykke Sørensen

  Keywords: age-related macular degeneration, drusen, myeloproliferative neoplasms, chronic low-grade inflammation, immunosenescence, T cells

  Published in Aging on December 26, 2021

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• Research PaperVolume 13, Issue 24pp 25944-25959

  Global, regional, and national burden of age-related hearing loss from 1990 to 2019

  Relevance score: 0.00

  Jinyu Man, Hui Chen, Tongchao Zhang, Xiaolin Yin, Xiaorong Yang, Ming Lu

  Keywords: age-related hearing loss, global burden of disease, DALYs, prevalent cases, temporal trend

  Published in Aging on December 15, 2021

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• Research PaperVolume 13, Issue 9pp 12359-12377

  Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization

  Relevance score: 0.00

  Quentin Roblain, Thomas Louis, Cassandre Yip, Louis Baudin, Ingrid Struman, Vincenza Caolo, Vincent Lambert, Julie Lecomte, Agnès Noël, Stephane Heymans

  Keywords: miR-142-3p, age-related macular degeneration, angiogenesis, inflammation, microglia

  Published in Aging on May 5, 2021

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• Research PaperVolume 13, Issue 9pp 12587-12606

  Neural presbycusis at ultra-high frequency in aged common marmosets and rhesus monkeys

  Relevance score: 0.00

  Zhuoer Sun, Zhenzhe Cheng, Neng Gong, Zhen Xu, Chenxi Jin, Hao Wu, Yong Tao

  Keywords: age-related hearing loss, non-human primate, deafness, neural degeneration

  Published in Aging on April 27, 2021

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 12, Issue 24pp 24836-24852

  miR-106b suppresses pathological retinal angiogenesis

  Relevance score: 0.00

  Catherine Ménard, Ariel M. Wilson, Agnieszka Dejda, Khalil Miloudi, François Binet, Sergio Crespo-Garcia, Célia Parinot, Frédérique Pilon, Rachel Juneau, Elisabeth MMA Andriessen, Gaëlle Mawambo, John Paul SanGiovanni, Vincent De Guire, Przemyslaw Sapieha

  Keywords: age related macular degeneration, miR-106b, PERK, choroidal neovascularization, angiogenesis

  Published in Aging on December 23, 2020

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• Research PaperVolume 12, Issue 17pp 17271-17287

  Profiling of circular RNAs in age-related cataract reveals circZNF292 as an antioxidant by sponging miR-23b-3p

  Relevance score: 0.00

  Shuqi Liang, Shengqian Dou, Wenfeng Li, Yusen Huang

  Keywords: age-related cataract, circRNAs, high-throughput sequencing, miRNAs, oxidative stress

  Published in Aging on September 10, 2020

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• Research PaperVolume 12, Issue 14pp 13905-13923

  Activation of C-reactive protein proinflammatory phenotype in the blood retinal barrier in vitro: implications for age-related macular degeneration

  Relevance score: 0.00

  Sara Romero-Vázquez, Alfredo Adán, Marc Figueras-Roca, Victor Llorenç, Mark Slevin, Gemma Vilahur, Lina Badimon, Andrew D Dick, Blanca Molins

  Keywords: age-related macular degeneration, retinal pigment epithelium, inflammation, C-reactive protein

  Published in Aging on July 16, 2020

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• Research PaperVolume 12, Issue 8pp 7491-7510

  RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model

  Relevance score: 0.00

  Tong Zhao, Xiuzhen Liu, Zehua Sun, Jinjin Zhang, Xiaolin Zhang, Chaoyun Wang, Ruishuang Geng, Tihua Zheng, Bo Li, Qing Yin Zheng

  Keywords: RNA-seq, lncRNA, age-related hearing loss, mRNA

  Published in Aging on April 26, 2020

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• Research PaperVolume 11, Issue 20pp 8982-8997

  Heat shock factor 1-mediated transcription activation of Omi/HtrA2 induces myocardial mitochondrial apoptosis in the aging heart

  Relevance score: 0.00

  Dan Liu, Linguo Wu, Ye Wu, Xin Wei, Wen Wang, Suli Zhang, Ming Yi, Jing Li, Huirong Liu, Xinliang Ma

  Keywords: age-related pathology, mitochondria, transcriptional regulation, cardiovascular, Omi/HtrA2

  Published in Aging on October 18, 2019

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• Research PaperVolume 11, Issue 17pp 6691-6713

  PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

  Relevance score: 0.00

  Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney

  Keywords: age-related macular degeneration (AMD), RPE, PGC-1α, mitochondria, FDA-approved drugs

  Published in Aging on September 2, 2019

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• Research PaperVolume 11, Issue 16pp 6134-6152

  Beta-amyloid induces apoptosis of neuronal cells by inhibition of the Arg/N-end rule pathway proteolytic activity

  Relevance score: 0.00

  Olga I. Kechko, Irina Yu. Petrushanko, Christopher S. Brower, Alexei A. Adzhubei, Alexey A. Moskalev, Konstantin I. Piatkov, Vladimir A. Mitkevich, Alexander A. Makarov

  Keywords: age-related disease, Alzheimer’s disease, apoptosis, Ate1, protein degradation

  Published in Aging on August 24, 2019

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• Research PaperVolume 11, Issue 10pp 3156-3169

  Age-related hearing loss accelerates cerebrospinal fluid tau levels and brain atrophy: a longitudinal study

  Relevance score: 0.00

  Wei Xu, Can Zhang, Jie-Qiong Li, Chen-Chen Tan, Xi-Peng Cao, Lan Tan, Jin-Tai Yu

  Keywords: age-related hearing loss, Alzheimer’s disease, biomarker, tau, MRI

  Published in Aging on May 22, 2019

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