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• ReviewVolume 13, Issue 5pp 7691-7706

  β cell aging and age-related diabetes

  Relevance score: 0.00

  Min Zhu, Xiaohong Liu, Wen Liu, Yanrong Lu, Jingqiu Cheng, Younan Chen

  Keywords: aging, type 2 diabetes (T2D), age-related diabetes, β cell function, β cell senescence

  Published in Aging on March 3, 2021

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• Research PaperVolume 5, Issue 5pp 373-385

  Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: A proof of principle on type 2 diabetes

  Relevance score: 0.00

  Paolo Garagnani, Cristina Giuliani, Chiara Pirazzini, Fabiola Olivieri, Maria Giulia Bacalini, Rita Ostan, Daniela Mari, Giuseppe Passarino, Daniela Monti, Anna Rita Bonfigli, Massimo Boemi, Antonio Ceriello, Stefano Genovese, Federica Sevini, Donata Luiselli, Paolo Tieri, Miriam Capri, Stefano Salvioli, Jan Vijg, Yousin Suh, Massimo Delledonne, Roberto Testa, Claudio Franceschi

  Keywords: Type 2 diabetes, TCF7L2, centenarians, extreme phenotypes, age-related diseases

  Published in Aging on May 31, 2013

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• Research PaperVolume 5, Issue 6pp 412-426

  A decline in PABPN1 induces progressive muscle weakness in Oculopharyngeal muscle dystrophy and in muscle aging

  Relevance score: 0.00

  Seyed Yahya Anvar, Yotam Raz, Nisha Verwey, Barbara van der Sluijs, Andrea Venema, Jelle J Goeman, John Vissing, Silvère M van der Maarel, Peter A.C. ‘t Hoen, Baziel G.M. van Engelen, Vered Raz

  Keywords: Type 2 diabetes, TCF7L2, centenarians, extreme phenotypes, age-related diseases

  Published in Aging on June 16, 2013

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• Research PaperVolume 16, Issue 20pp 13132-13144

  OSBPL2 inhibition leads to apoptosis of cochlea hair cells in age-related hearing loss by inhibiting the AKT/FOXG1 signaling pathway

  Relevance score: 0.00

  Meina Li-Yang, Chao Ma, Xiaoye Wang, Jianqiang You

  Keywords: age-related hearing loss, OSBPL2, FOXG1, AKT, cochlea hair cells

  Published in Aging on October 30, 2024

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• Research PaperVolume 16, Issue 9pp 8044-8069

  Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

  Relevance score: 0.00

  Shan Luo, Qiang Hu, Bo Jiang, Zhongyu Zhang, Dawei Sun

  Keywords: age-related macular degeneration, cellular senescence, programmed cell death, inflammatory response, molecular subtypes

  Published in Aging on May 10, 2024

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• Research PaperVolume 15, Issue 20pp 10856-10874

  Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes

  Relevance score: 0.00

  María Marchante, Noelia Ramirez-Martin, Anna Buigues, Jessica Martinez, Nuria Pellicer, Antonio Pellicer, Sonia Herraiz

  Keywords: age-related infertility, ovarian aging, mouse model, oocyte quality, embryo development, mitochondrial function

  Published in Aging on October 16, 2023

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• Research PaperVolume 15, Issue 10pp 4498-4509

  Expression of αA-crystallin (CRYAA) in vivo and in vitro models of age-related cataract and the effect of its silencing on HLEB3 cells

  Relevance score: 0.00

  Xiaoling Ma, Yi Nan, Can Huang, Xiangyang Li, Yifan Yang, Wenjie Jiang, Mengyi Ye, Qian Liu, Yang Niu, Ling Yuan

  Keywords: age-related cataract, CRYAA

  Published in Aging on May 28, 2023

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• Research PaperVolume 15, Issue 6pp 1713-1733

  Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

  Relevance score: 0.00

  Tu Nguyen, Daniel Urrutia-Cabrera, Luozixian Wang, Jarmon G. Lees, Jiang-Hui Wang, Sandy S.C. Hung, Alex W. Hewitt, Thomas L. Edwards, Sam McLenachan, Fred K. Chen, Shiang Y. Lim, Chi D. Luu, Robyn Guymer, Raymond C.B. Wong

  Keywords: age-related macular degeneration, retina, CRISPR/Cas, mitochondria superoxide, POLDIP2

  Published in Aging on February 16, 2023

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• Research PaperVolume 15, Issue 1pp 37-52

  Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

  Relevance score: 0.00

  Chi-Hsiu Liu, Felix Yemanyi, Kiran Bora, Neetu Kushwah, Alexandra K. Blomfield, Theodore M. Kamenecka, John Paul SanGiovanni, Ye Sun, Laura A. Solt, Jing Chen

  Keywords: age-related macular degeneration, angiogenesis, choroidal neovascularization, inflammation, nuclear receptors, RORα, VEGFR2, TNFα

  Published in Aging on January 10, 2023

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• Research PaperVolume 13, Issue 24pp 25763-25777

  Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

  Relevance score: 0.00

  Charlotte Liisborg, Vibe Skov, Lasse Kjær, Hans Carl Hasselbalch, Torben Lykke Sørensen

  Keywords: age-related macular degeneration, drusen, myeloproliferative neoplasms, chronic low-grade inflammation, immunosenescence, T cells

  Published in Aging on December 26, 2021

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• Research PaperVolume 13, Issue 24pp 25944-25959

  Global, regional, and national burden of age-related hearing loss from 1990 to 2019

  Relevance score: 0.00

  Jinyu Man, Hui Chen, Tongchao Zhang, Xiaolin Yin, Xiaorong Yang, Ming Lu

  Keywords: age-related hearing loss, global burden of disease, DALYs, prevalent cases, temporal trend

  Published in Aging on December 15, 2021

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• Research PaperVolume 13, Issue 9pp 12359-12377

  Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization

  Relevance score: 0.00

  Quentin Roblain, Thomas Louis, Cassandre Yip, Louis Baudin, Ingrid Struman, Vincenza Caolo, Vincent Lambert, Julie Lecomte, Agnès Noël, Stephane Heymans

  Keywords: miR-142-3p, age-related macular degeneration, angiogenesis, inflammation, microglia

  Published in Aging on May 5, 2021

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• Research PaperVolume 13, Issue 9pp 12587-12606

  Neural presbycusis at ultra-high frequency in aged common marmosets and rhesus monkeys

  Relevance score: 0.00

  Zhuoer Sun, Zhenzhe Cheng, Neng Gong, Zhen Xu, Chenxi Jin, Hao Wu, Yong Tao

  Keywords: age-related hearing loss, non-human primate, deafness, neural degeneration

  Published in Aging on April 27, 2021

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 12, Issue 24pp 24836-24852

  miR-106b suppresses pathological retinal angiogenesis

  Relevance score: 0.00

  Catherine Ménard, Ariel M. Wilson, Agnieszka Dejda, Khalil Miloudi, François Binet, Sergio Crespo-Garcia, Célia Parinot, Frédérique Pilon, Rachel Juneau, Elisabeth MMA Andriessen, Gaëlle Mawambo, John Paul SanGiovanni, Vincent De Guire, Przemyslaw Sapieha

  Keywords: age related macular degeneration, miR-106b, PERK, choroidal neovascularization, angiogenesis

  Published in Aging on December 23, 2020

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• Research PaperVolume 12, Issue 17pp 17271-17287

  Profiling of circular RNAs in age-related cataract reveals circZNF292 as an antioxidant by sponging miR-23b-3p

  Relevance score: 0.00

  Shuqi Liang, Shengqian Dou, Wenfeng Li, Yusen Huang

  Keywords: age-related cataract, circRNAs, high-throughput sequencing, miRNAs, oxidative stress

  Published in Aging on September 10, 2020

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• Research PaperVolume 12, Issue 14pp 13905-13923

  Activation of C-reactive protein proinflammatory phenotype in the blood retinal barrier in vitro: implications for age-related macular degeneration

  Relevance score: 0.00

  Sara Romero-Vázquez, Alfredo Adán, Marc Figueras-Roca, Victor Llorenç, Mark Slevin, Gemma Vilahur, Lina Badimon, Andrew D Dick, Blanca Molins

  Keywords: age-related macular degeneration, retinal pigment epithelium, inflammation, C-reactive protein

  Published in Aging on July 16, 2020

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• Research PaperVolume 12, Issue 8pp 7491-7510

  RNA-seq analysis of potential lncRNAs for age-related hearing loss in a mouse model

  Relevance score: 0.00

  Tong Zhao, Xiuzhen Liu, Zehua Sun, Jinjin Zhang, Xiaolin Zhang, Chaoyun Wang, Ruishuang Geng, Tihua Zheng, Bo Li, Qing Yin Zheng

  Keywords: RNA-seq, lncRNA, age-related hearing loss, mRNA

  Published in Aging on April 26, 2020

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• Research PaperVolume 11, Issue 20pp 8982-8997

  Heat shock factor 1-mediated transcription activation of Omi/HtrA2 induces myocardial mitochondrial apoptosis in the aging heart

  Relevance score: 0.00

  Dan Liu, Linguo Wu, Ye Wu, Xin Wei, Wen Wang, Suli Zhang, Ming Yi, Jing Li, Huirong Liu, Xinliang Ma

  Keywords: age-related pathology, mitochondria, transcriptional regulation, cardiovascular, Omi/HtrA2

  Published in Aging on October 18, 2019

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• Research PaperVolume 11, Issue 17pp 6691-6713

  PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

  Relevance score: 0.00

  Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney

  Keywords: age-related macular degeneration (AMD), RPE, PGC-1α, mitochondria, FDA-approved drugs

  Published in Aging on September 2, 2019

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