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• Research PaperVolume 16, Issue 20pp 13132-13144

  OSBPL2 inhibition leads to apoptosis of cochlea hair cells in age-related hearing loss by inhibiting the AKT/FOXG1 signaling pathway

  Relevance score: 0.00

  Meina Li-Yang, Chao Ma, Xiaoye Wang, Jianqiang You

  Keywords: age-related hearing loss, OSBPL2, FOXG1, AKT, cochlea hair cells

  Published in Aging on October 30, 2024

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• Research PaperVolume 16, Issue 17pp 12239-12251

  MTA2 knockdown suppresses human osteosarcoma metastasis by inhibiting uPA expression

  Relevance score: 0.00

  Chun Tseng, Chien-Min Chen, Yi-Hsien Hsieh, Chia-Yu Lin, Jian-Wen Chen, Pang-Hsuan Hsiao, Yi-Chin Fong, Pei-Han Wang, Pei-Ni Chen, Renn-Chia Lin

  Keywords: osteosarcoma, MTA2, metastasis, ERK, uPA

  Published in Aging on September 6, 2024

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• Research PaperVolume 16, Issue 17pp 12346-12378

  Decisive gene strategy on osteoarthritis: a comprehensive whole-literature based approach for conclusive gene targets

  Relevance score: 0.00

  Yi-Chou Chen, Yu-Chiao Wang, Meng-Chang Lee, Yu-Hsuan Chen, Wen Su, Pi-Shao Ko, Cheng-Jung Chen, Sui-Lung Su

  Keywords: osteoarthritis (OA), decisive gene strategy (DGS), trial sequential analysis (TSA)

  Published in Aging on September 6, 2024

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• Research PaperVolume 16, Issue 18pp 12559-12573

  The joint protective function of live- and dead-Lactobacillus plantarum GKD7 on anterior cruciate ligament transection induces osteoarthritis

  Relevance score: 0.00

  Yen-You Lin, Chih-Ying, Wu, You-Shan Tsai, Chin-Chu Chen, Tzu-Ching Chang, Li-Chai Chen, Hsien-Te Chen, Chin-Jung Hsu, Chih-Hsin Tang

  Keywords: osteoarthritis (OA), Lactobacillus plantarum GKD7, metalloproteinase (MMP)3, collage II, aggrecan

  Published in Aging on September 5, 2024

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• Research PaperVolume 16, Issue 17pp 12263-12276

  Excessive glucocorticoids combined with RANKL promote the differentiation of bone marrow macrophages (BMM) into osteoclasts and accelerate the progression of osteoporosis by activating the SYK/SHP2/NF-κB signaling pathway

  Relevance score: 0.00

  Hao Dong, Xiaocong Liu, Jiqiang Duan, Jing Zhang, Hao Liu, Tiehui Shen

  Keywords: osteoporosis, glucocorticoids, BMM, RANKL, SYK/SHP2/NF-κB signaling pathway

  Published in Aging on August 27, 2024

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• Research PaperVolume 16, Issue 16pp 11926-11938

  Caffeic acid derivative MPMCA suppresses osteoclastogenesis and facilitates osteoclast apoptosis: implications for the treatment of bone loss disorders

  Relevance score: 0.00

  Le Huynh Hoai Thuong, Chin-Jung Hsu, Hsien-Te Chen, Yueh-Hsiung Kuo, Chih-Hsin Tang

  Keywords: MPMCA, osteoclastogenesis, apoptosis, MAPK, NF-κB

  Published in Aging on August 26, 2024

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• Research PaperVolume 16, Issue 15pp 11568-11576

  Circular RNA circMRPS35 represses malignant progression in osteosarcoma cells via targeting miR-105-5p/FOXO1

  Relevance score: 0.00

  Chunshan Jiang, Zhe Jiang, Xuewu Zhang

  Keywords: osteosarcoma, progression, circMRPS35, miR-105-5p, FOXO1

  Published in Aging on August 5, 2024

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• Research Paper

  Ginsenoside Rh4 reverses ABCB1-induced doxorubicin resistance via the PI3Kδ/AKT axis in osteosarcoma

  Relevance score: 0.00

  Tianqi Xia, Xinyan Shen, Huidong Chen, Yan Zhang, Yi Xu, Shen Zan, Daliu Min, Yonggang Wang

  Keywords: osteosarcoma, multidrug resistance, ginsenoside Rh4, ABCB1, PI3Kδ/AKT signaling pathway

  Published in Aging on July 15, 2024

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• Research PaperVolume 16, Issue 13pp 10841-10859

  Characterization of the gut microbiota and fecal metabolome in the osteosarcoma mouse model

  Relevance score: 0.00

  Yuan Li, Xiaochen Qiao, Yi Feng, Ruhao Zhou, Kun Zhang, Yongchun Pan, Ting Yan, Lei Yan, Sen Yang, Xiaochun Wei, Pengcui Li, Chaojian Xu, Zhi Lv, Zhi Tian

  Keywords: osteosarcoma, animal model, gut microbiota, 16S rDNA sequencing, non-targeted metabolomics

  Published in Aging on July 3, 2024

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• Research PaperVolume 16, Issue 14pp 11208-11223

  Cyclin L1 participates in Adriamycin resistance and progression of osteosarcoma via PI3K/AKT-mTOR pathway

  Relevance score: 0.00

  Yanbin Zhang, Tao Zhang, Long Chen, Zijun Guo, Xiaobing Jiang

  Keywords: osteosarcoma, CCNL1, chemoresistance, PI3K/AKT-mTOR, Adriamycin, prognosis

  Published in Aging on June 26, 2024

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• Research PaperVolume 16, Issue 11pp 9558-9568

  The protective effects of orexin-A in alleviating cell senescence against interleukin-1β (IL-1β) in chondrocytes

  Relevance score: 0.00

  Lin Shen, Xiantie Zeng, Haiying Zhang

  Keywords: osteoarthritis, orexin-A, cell senescence, IL-1β, SIRT3

  Published in Aging on May 31, 2024

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• Research PaperVolume 16, Issue 11pp 9437-9459

  Machine learning-based identification and immune characterization of ferroptosis-related molecular clusters in osteoarthritis and validation

  Relevance score: 0.00

  Xiaocheng Guo, Xinyuan Feng, Yue Yang, Wenying An, Lunhao Bai

  Keywords: osteoarthritis, ferroptosis, differentially expressed genes, immune characteristics, molecular clusters

  Published in Aging on May 29, 2024

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• Research PaperVolume 16, Issue 9pp 8155-8170

  Bioinformatics analysis and validation of mesenchymal stem cells related gene MT1G in osteosarcoma

  Relevance score: 0.00

  Sikuan Zheng, Xifu Cheng, Sulun Ke, Linyi Zhang, Hui Wu, Dingwen He, Xigao Cheng

  Keywords: osteosarcoma, MT1G, mesenchymal stem cells, prognosis

  Published in Aging on May 13, 2024

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• Research PaperVolume 16, Issue 9pp 8198-8216

  RNA sequencing-based approaches to identifying disulfidptosis-related diagnostic clusters and immune landscapes in osteoporosis

  Relevance score: 0.00

  Peng Zhang, Bing Li, Honglin Chen, Zhilin Ge, Qi Shang, De Liang, Xiang Yu, Hui Ren, Xiaobing Jiang, Jianchao Cui

  Keywords: osteoporosis, disulfidptosis modulator, subtype classification, risk prediction, RNA sequencing

  Published in Aging on May 10, 2024

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• Research PaperVolume 16, Issue 8pp 7043-7059

  Identification of biomarkers and immune infiltration characterization of lipid metabolism-associated genes in osteoarthritis based on machine learning algorithms

  Relevance score: 0.00

  Yuanye Ma, Yang Liu, Dan Luo, Zhu Guo, Hongfei Xiang, Bohua Chen, Xiaolin Wu

  Keywords: osteoarthritis, lipid metabolism associated gene, machine learning algorithms, immune infiltration, biomarkers

  Published in Aging on April 17, 2024

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• Research PaperVolume 16, Issue 5pp 4832-4840

  Chlorogenic acid prevents ovariectomized-induced bone loss by facilitating osteoblast functions and suppressing osteoclast formation

  Relevance score: 0.00

  Chien-Yi Ho, Chih-Hsin Tang, Trung-Loc Ho, Wen-Ling Wang, Chun-Hsu Yao

  Keywords: chlorogenic acid, osteoporosis, ovariectomized, osteoclast, osteoblast

  Published in Aging on March 9, 2024

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• Research PaperVolume 16, Issue 6pp 5249-5263

  Molecular characterization of Golgi apparatus-related genes indicates prognosis and immune infiltration in osteosarcoma

  Relevance score: 0.00

  Jian Zhang, Jiahao Liu, Rui Ding, Xinxin Miao, Jianjian Deng, Xiaokun Zhao, Tianlong Wu, Xigao Cheng

  Keywords: osteosarcoma, Golgi apparatus, biomarkers, prognosis, immune infiltration

  Published in Aging on March 7, 2024

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• Research PaperVolume 16, Issue 5pp 4579-4590

  A novel classification predicts prognosis and drug sensitivity in osteosarcoma based on alterations in gene sets

  Relevance score: 0.00

  Shuxi Ye, Xiaopeng Wang, Rongchun Chen

  Keywords: osteosarcoma, pathways, tumor microenvironment, drug sensitivity

  Published in Aging on February 28, 2024

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• Research PaperVolume 16, Issue 5pp 4563-4578

  Machine learning-based endoplasmic reticulum-related diagnostic biomarker and immune microenvironment landscape for osteoarthritis

  Relevance score: 0.00

  Tingting Liu, Xiaomao Li, Mu Pang, Lifen Wang, Ye Li, Xizhe Sun

  Keywords: osteoarthritis, endoplasmic reticulum, diagnostic biomarker, immune microenvironment, machine learning

  Published in Aging on February 28, 2024

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• Research PaperVolume 16, Issue 4pp 3694-3715

  PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis

  Relevance score: 0.00

  Tao Li, Jinghong Yuan, Peichuan Xu, Jingyu Jia, Jiangminghao Zhao, Jian Zhang, Rui Ding, Xiaokun Zhao, Dingwen He, Tianlong Wu, Xigao Cheng

  Keywords: osteoporosis, transcription factors, BMSC, ceRNA, diagnosis

  Published in Aging on February 16, 2024

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