Volume 16, Issue 14

July 31, 2024pp 11122—11478

About the Cover

The cover features Figure 3 "Comparison of change in LTL over the 2-year follow-up according to osteoporosis" from Han et al.

Editorials

Targeted cancer therapy: the initial high concentration may slow down the selection for resistance

Mikhail V. Blagosklonny

https://doi.org/10.18632/aging.206046pp 11122—11124

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Recalibrate concepts of epigenetic aging clocks in human health

Ze Zhang, Brock C. Christensen, Lucas A. Salas

https://doi.org/10.18632/aging.206027pp 11125—11127

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Research Perspective

Lipid accumulation drives cellular senescence in dopaminergic neurons

Taylor Russo, Markus Riessland

https://doi.org/10.18632/aging.206030pp 11128—11133

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Research Papers

mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease

Karl Berner, Naci Oz, Alaattin Kaya, Animesh Acharjee, Jon Berner

https://doi.org/10.18632/aging.206033pp 11134—11150

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Association between osteoporosis and the rate of telomere shortening

Myung-Hoon Han, Hyuk Sung Kwon, Mina Hwang, Hyun-Hee Park, Jee Hyang Jeong, Kyung Won Park, Eun-Joo Kim, Soo Jin Yoon, Bora Yoon, Jae-Won Jang, Jin Yong Hong, Seong Hye Choi, Seong-Ho Koh

https://doi.org/10.18632/aging.206034pp 11151—11161

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Prognostic relevance and validation of ARPC1A in the progression of low-grade glioma

Jingyuan Dai, Jiahui Gao, Hongchao Dong

https://doi.org/10.18632/aging.205952pp 11162—11184

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Identification of immunotherapy-related subtypes, characterization of tumor microenvironment infiltration, and development of a prognostic signature in gastric carcinoma

Jianxin Li, Ting Han, Jieyi Yang, Xin Wang, Yinchun Wang, Rui Yang, Qingqiang Yang

https://doi.org/10.18632/aging.205968pp 11185—11207

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Cyclin L1 participates in Adriamycin resistance and progression of osteosarcoma via PI3K/AKT-mTOR pathway

Yanbin Zhang, Tao Zhang, Long Chen, Zijun Guo, Xiaobing Jiang

https://doi.org/10.18632/aging.205972pp 11208—11223

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Pan-cancer analysis of T-cell proliferation regulatory genes as potential immunotherapeutic targets

Ruqiong Wei, Shihui Xiao, Shijian Zhao, Wenliang Guo, Ying Liu, Marìa del Mar Requena Mullor, Raquel Alarcòn Rodrìguez, Qingjun Wei, Yinteng Wu

https://doi.org/10.18632/aging.205977pp 11224—11247

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A stemness-based signature with inspiring indications in discriminating the prognosis, immune response, and somatic mutation of endometrial cancer patients revealed by machine learning

Xuecheng Pang, Yu Wang, Qiang Zhang, Sumin Qian

https://doi.org/10.18632/aging.205979pp 11248—11274

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Interference with ANXA8 inhibits the malignant progression of ovarian cancer by suppressing the activation of the Wnt/β-catenin signaling pathway via UCHL5

Li Xu, Liang Wang, Yaping Gan, Jiazhi Lin, Shuting Ning, Jinjin Deng, Yingxia Ning, Weifeng Feng

https://doi.org/10.18632/aging.205991pp 11275—11288

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Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy

Siying Wang, Xuyu Chen, Xiaofei Zhang, Kang Wen, Xin Chen, Jingyao Gu, Juan Li, Zhaoxia Wang

https://doi.org/10.18632/aging.206003pp 11289—11317

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Consensus clustering and novel risk score model construction based on m6A methylation regulators to evaluate the prognosis and tumor immune microenvironment of early-stage lung adenocarcinoma

Miao He, Yuxue Zhi, Chao Li, Changming Zhao, Guangquan Yang, Jing Lv, Hong You, Hai Huang, Xiaoyu Cao

https://doi.org/10.18632/aging.206004pp 11318—11338

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PART1 facilitates tumorigenesis and inhibits ferroptosis by regulating the miR-490-3p/SLC7A11 axis in hepatocellular carcinoma

Decheng Li, Meiling Wan, Xiaoling Liu, Suvash Chandra Ojha, Yunjian Sheng, Yaling Li, Changfeng Sun, Cunliang Deng

https://doi.org/10.18632/aging.206009pp 11339—11358

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Effect of body mass index on mortality for diabetic patients with aortic stenosis

Kai-Chun Chang, Li-Ting Ho, Kuan-Chih Huang, Jung-Chi Hsu, David Te-Wei Kuan, Ting-Tse Lin, Jen-Kuang Lee, Yen-Yun Yang, Shu-Lin Chuang, Lian-Yu Lin

https://doi.org/10.18632/aging.206018pp 11359—11372

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High expression of circulating exosomal PD-L1 contributes to immune escape of hepatocellular carcinoma and immune clearance of chronic hepatitis B

Xiaoqing Lin, Hui Shao, Yongzhi Tang, Qiupeng Wang, Zhenyu Yang, Hongwei Wu, Tongjing Xing

https://doi.org/10.18632/aging.206020pp 11373—11384

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Integrating single-cell RNA-seq to identify fibroblast-based molecular subtypes for predicting prognosis and therapeutic response in bladder cancer

Jia Wang, Zhiyong Tan, Yinglong Huang, Charles Li, Peiqin Zhan, Haifeng Wang, Haihao Li

https://doi.org/10.18632/aging.206021pp 11385—11408

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Discovery of differentially expressed proteins for CAR-T therapy of ovarian cancers with a bioinformatics analysis

Dito Anurogo, Chao-Lien Liu, Yu-Chu Chang, Yu-Hsiang Chang, J. Timothy Qiu

https://doi.org/10.18632/aging.206024pp 11409—11433

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Systematic characterization of the expression, prognosis and immune characteristics of PLOD family genes in breast cancer

Dan-Dan Wang, Lei Li, Yu-Qi Fu, Su-Jin Yang, Xiu Chen, Jun-Chen Hou, Qian Zhang, Xiao-Xue Tian, Jin-Hai Tang, Jian Zhang, He-Da Zhang

https://doi.org/10.18632/aging.206029pp 11434—11445

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Effectiveness of vaginal probiotics Lactobacillus crispatus chen-01 in women with high-risk HPV infection: a prospective controlled pilot study

Yujuan Liu, Xiumiao Zhao, Fei Wu, Jie Chen, Juanzhen Luo, Chunling Wu, Tingtao Chen

https://doi.org/10.18632/aging.206032pp 11446—11459

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Review

Circulating tumor DNA mutation analysis: advances in its application for early diagnosis of hepatocellular carcinoma and therapeutic efficacy monitoring

Jing Yang, Na Lin, Miaomiao Niu, Boshu Yin

https://doi.org/10.18632/aging.205980pp 11460—11474

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Correction

Correction for: Iron retardation in lysosomes protects senescent cells from ferroptosis

Yujing Feng, Huaiqing Wei, Meng Lyu, Zhiyuan Yu, Jia Chen, Xinxing Lyu, Fengfeng Zhuang

https://doi.org/10.18632/aging.206052pp 11475—11476

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Retraction

Retraction of: Long noncoding RNA NR2F1-AS1 promotes the malignancy of non-small cell lung cancer via sponging microRNA-493-5p and thereby increasing ITGB1 expression

Chan Zhang, Shangjie Wu, Rong Song, Changming Liu

https://doi.org/10.18632/aging.206050pp 11477—11478

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