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• Research PaperVolume 15, Issue 10pp 4288-4303

  DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo

  Relevance score: 0.00

  Yang Hou, Jiangang Shi, Yongfei Guo, Guodong Shi

  Keywords: intervertebral disc degeneration, macrophage polarization, DNA methyltransferase 1, sirtuin 6

  Published in Aging on May 17, 2023

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• Research PaperVolume 17, Issue 8pp 2113-2125

  DNMT1-mediated SPINT2 expression drives early senescence by suppressing c-Met signaling in human fibroblasts

  Relevance score: 0.00

  Min Seok Sim, Hae-Ok Byun, Seongki Min, Jiwon Hong, Su Bin Lim, Kyoung Sook Choi, Gyesoon Yoon

  Keywords: senescence, cellular senescence, aging, DNA methyltransferase 1 (DNMT1), serine protease inhibitor Kunitz type 2 (SPINT2)

  Published in Aging on August 20, 2025

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• Research PaperVolume 12, Issue 8pp 6558-6569

  Epigenetic modulation of macrophage polarization prevents lumbar disc degeneration

  Relevance score: 0.00

  Yang Hou, Guodong Shi, Yongfei Guo, Jiangang Shi

  Keywords: lumbar disc degeneration (LDD), aging, macrophage polarization, DNA methyltransferase 1 (DNMT1), transforming growth factor beta 1 (TGFβ1)

  Published in Aging on April 20, 2020

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• Research PaperVolume 12, Issue 23pp 23668-23683

  DNMT3B silencing suppresses migration and invasion by epigenetically promoting miR-34a in bladder cancer

  Relevance score: 0.00

  Kai Xu, Binshen Chen, Bingkun Li, Chaoming Li, Yiming Zhang, Ning Jiang, Bin Lang

  Keywords: DNA methyltransferase 3B, metastasis, miR-34a promotor, methylation, bladder cancer

  Published in Aging on November 20, 2020

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• Research PaperVolume 13, Issue 10pp 14289-14303

  Autophagy deficiency downregulates O⁶methylguanine-DNA methyltransferase and increases chemosensitivity of liver cancer cells

  Relevance score: 0.00

  Xiaojuan Hou, Changchun Shao, Kai Sun, Rong Li, Lu Gao, Yan Meng, Yingying Jing, Lixin Wei

  Keywords: autophagy deficiency, DNA damage, O⁶methylguanine-DNA methyltransferase (MGMT), chemosensitivity, liver cancer

  Published in Aging on May 24, 2021

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• RetractionVolume 16, Issue 10pp 9305-9305

  Retraction for: DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis

  Relevance score: 0.00

  Zhiqiang Luo, Yanchao Ma, Tianning Di, Bing Ma, Hongwei Li, Jiangdong An, Yonggang Wang, Haihong Zhang

  Keywords: intervertebral disc degeneration, nucleus pulposus, extracellular matrix, inflammation, DNA methyltransferase

  Published in Aging on May 31, 2024

• Research PaperVolume 13, Issue 16pp 20258-20276

  DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis

  Relevance score: 0.00

  Zhiqiang Luo, Yanchao Ma, Tianning Di, Bing Ma, Hongwei Li, Jiangdong An, Yonggang Wang, Haihong Zhang

  Keywords: intervertebral disc degeneration, nucleus pulposus, extracellular matrix, inflammation, DNA methyltransferase

  Published in Aging on August 24, 2021

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• Research PaperVolume 17, Issue 7pp 1702-1720

  Second generation DNA methylation age predicts cognitive change in midlife: the moderating role of childhood socioeconomic status

  Relevance score: 0.00

  Sophie A. Bell, Christopher R. Beam, Ebrahim Zandi, Alyssa Kam, Emily Andrews, Jonathan Becker, Deborah Finkel, Deborah W. Davis, Eric Turkheimer

  Keywords: epigenetic age, cognition, socioeconomic status, DNA methylation, lifespan

  Published in Aging on July 23, 2025

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• Research PaperVolume 17, Issue 3pp 685-698

  DNA methylation entropy is a biomarker for aging

  Relevance score: 0.00

  Jonathan Chan, Liudmilla Rubbi, Matteo Pellegrini

  Keywords: entropy, DNA methylation, aging, epigenetics, epigenetic clocks

  Published in Aging on March 12, 2025

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• Priority Research PaperVolume 16, Issue 22pp 13452-13504

  Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution

  Relevance score: 0.00

  Huige Tong, Xiaolong Guo, Macsue Jacques, Qi Luo, Nir Eynon, Andrew E. Teschendorff

  Keywords: DNA methylation, epigenetic clocks, cell-type deconvolution, biological aging, Alzheimer’s disease, obesity

  Published in Aging on December 29, 2024

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• Research PaperVolume 16, Issue 22pp 13534-13562

  DNA-methylation age and accelerated epigenetic aging in blood as a tumor marker for predicting breast cancer susceptibility

  Relevance score: 0.00

  Su Yon Jung, Herbert Yu, Youping Deng, Matteo Pellegrini

  Keywords: DNA methylation-based marker of aging, pre-diagnostic DNA, breast cancer, tumorigenesis, postmenopausal women

  Published in Aging on December 5, 2024

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• EditorialVolume 16, Issue 15pp 11479-11481

  Physical fitness and lifestyles associated with biological aging

  Relevance score: 0.00

  Takuji Kawamura, Radak Zsolt, Mitsuru Higuchi, Kumpei Tanisawa

  Keywords: DNA methylation, epigenetic clock, physical fitness, anthropometry, blood biochemical parameters, nutritional intake

  Published in Aging on July 19, 2024

• Research PaperVolume 16, Issue 8pp 6694-6716

  The association between neighborhood deprivation and DNA methylation in an autopsy cohort

  Relevance score: 0.00

  Lindsay Pett, Zhenjiang Li, Sarina Abrishamcar, Kenyaita Hodge, Todd Everson, Grace Christensen, Marla Gearing, Michael S. Kobor, Chaini Konwar, Julia L. MacIsaac, Kristy Dever, Aliza P. Wingo, Allan Levey, James J. Lah, Thomas S. Wingo, Anke Hüls

  Keywords: DNA methylation, brain tissue, neighborhood deprivation, neuropathology, epigenetics

  Published in Aging on April 24, 2024

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• CorrectionVolume 16, Issue 5pp 4943-4945

  Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial

  Relevance score: 0.00

  Kara N. Fitzgerald, Romilly Hodges, Douglas Hanes, Emily Stack, David Cheishvili, Moshe Szyf, Janine Henkel, Melissa W. Twedt, Despina Giannopoulou, Josette Herdell, Sally Logan, Ryan Bradley

  Keywords: DNA methylation, epigenetic, aging, lifestyle, biological clock

  Published in Aging on March 15, 2024

• Priority Research PaperVolume 15, Issue 17pp 8552-8575

  Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease

  Relevance score: 0.00

  Xiaoyue Mei, Joshua Blanchard, Connor Luellen, Michael J. Conboy, Irina M. Conboy

  Keywords: DNA methylation, epigenetics, aging, clocks’ fail-tests, biological noise

  Published in Aging on September 12, 2023

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• Research PaperVolume 15, Issue 15pp 7424-7439

  DNA methylation-mediated high expression of CCDC50 correlates with poor prognosis and hepatocellular carcinoma progression

  Relevance score: 0.00

  Chunhong Li, Yingdong Jia, Na Li, Qiang Zhou, Rui Liu, Qiang Wang

  Keywords: CCDC50, DNA methylation, prognostic value, hepatocellular carcinoma, immune cell infiltra

  Published in Aging on August 7, 2023

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• Research PaperVolume 15, Issue 14pp 6798-6821

  Molecular subtypes based on DNA sensors predict prognosis and tumor immunophenotype in hepatocellular carcinoma

  Relevance score: 0.00

  Hong-Sheng Lin, Wen-Peng Pang, Hao Yuan, Yin-Zhi Kong, Fu-Li Long, Rong-Zhen Zhang, Li Yang, Qiao-Ling Fang, Ai-Ping Pan, Xiao-Hui Fan, Ming-Fen Li

  Keywords: hepatocellular carcinoma, DNA sensors, immune microenvironment, prognosis, immunotherapy

  Published in Aging on July 14, 2023

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• Research PaperVolume 15, Issue 6pp 1833-1839

  Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series

  Relevance score: 0.00

  Kara N. Fitzgerald, Tish Campbell, Suzanne Makarem, Romilly Hodges

  Keywords: DNA methylation, epigenetic, aging, lifestyle, biological clock

  Published in Aging on March 22, 2023

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• Research PaperVolume 15, Issue 3pp 765-776

  Senolytic effect of high intensity interval exercise on human skeletal muscle

  Relevance score: 0.00

  Wei-Horng Jean, Yu-Wen Hsieh, Li-Fan Lai, Luthfia Dewi, Yu-Chieh Liao, Mengxin Ye, Szu-Hsien Yu, Chung-Lan Kao, Chih-Yang Huang, Chia-Hua Kuo

  Keywords: DNA repair, inflammation, p16^Ink4a, γ-H2AX, CD11b, HIIT, cycling

  Published in Aging on February 8, 2023

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• Research PaperVolume 15, Issue 3pp 617-629

  Epigenetic age and lung cancer risk in the CLUE II prospective cohort study

  Relevance score: 0.00

  Dominique S. Michaud, Mei Chung, Naisi Zhao, Devin C. Koestler, Jiayun Lu, Elizabeth A. Platz, Karl T. Kelsey

  Keywords: DNA methylation, epigenetic clocks, lung cancer, cohort study

  Published in Aging on February 7, 2023

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