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• Research PaperVolume 13, Issue 14pp 18993-19012

  A network pharmacology approach to uncover the key ingredients in Ginkgo Folium and their anti-Alzheimer’s disease mechanisms

  Relevance score: 0.00

  Peng Zeng, Meng Fang, Han Zhao, Jing Guo

  Keywords: Alzheimer’s disease, Ginkgo Folium, network pharmacology, genkwanin, AD pathology

  Published in Aging on July 27, 2021

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• Research PaperVolume 11, Issue 18pp 7978-7995

  GSK-3β and ERK1/2 incongruously act in tau hyperphosphorylation in SPS-induced PTSD rats

  Relevance score: 0.00

  Zhen Wei, Yacoubou Abdoul Razak Mahaman, Feiqi Zhu, Mengjuan Wu, Yiyuan Xia, Kuan Zeng, Ying Yang, Rong Liu, Jian-Zhi Wang, Xiji Shu, Xiaochuan Wang

  Keywords: post-traumatic stress disorder (PTSD), single prolonged stress (SPS), Alzheimer disease (AD), tau phosphorylation, GSK-3β

  Published in Aging on September 23, 2019

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• Research PaperVolume 14, Issue 19pp 8077-8094

  Novel small molecular compound 2JY-OBZ4 alleviates AD pathology in cell models via regulating multiple targets

  Relevance score: 0.00

  Qian Guo, Gang Wu, Fang Huang, Zhen Wei, Jian-Zhi Wang, Bin Zhang, Rong Liu, Yang Yang, Xiaochuan Wang, Hong-Lian Li

  Keywords: Alzheimer’s disease (AD), Huperzine A (Hup-A), beta-secretase 1 (BACE1), protein phosphatase- 2A (PP2A), cholinesterase inhibitor

  Published in Aging on October 12, 2022

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• Research PaperVolume 12, Issue 3pp 2897-2920

  Identifying lncRNA–miRNA–mRNA networks to investigate Alzheimer’s disease pathogenesis and therapy strategy

  Relevance score: 0.00

  Nana Ma, Changrui Tie, Bo Yu, Wei Zhang, Jun Wan

  Keywords: Alzheimer’s disease (AD), ceRNA network, APP/PS1 mouse, RNA-sequencing, lncRNA

  Published in Aging on February 7, 2020

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• Research PaperVolume 15, Issue 17pp 9022-9040

  Causal relationship between Alzheimer’s disease and cardiovascular disease: a bidirectional Mendelian randomization analysis

  Relevance score: 0.00

  Fengjun Zhang, Dexian Xian, Junchen Feng, Luning Ning, Tianshou Jiang, Wenchang Xu, Yuan Liu, Qiong Zhao, Min Peng

  Keywords: Alzheimer's disease (AD), cardiovascular disease (CVD), causality, bidirectional mendelian randomization (MR) study, genome-wide association study (GWAS)

  Published in Aging on September 2, 2023

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• Research PaperVolume 13, Issue 11pp 14940-14967

  Identification of key transcriptome biomarkers based on a vital gene module associated with pathological changes in Alzheimer’s disease

  Relevance score: 0.00

  Tong Zhang, Yang Shen, Yiqing Guo, Junyan Yao

  Keywords: Alzheimer's disease (AD), β-amyloid (Aβ), phosphorylated tau (p-tau), gene module, transcriptome biomarker

  Published in Aging on May 24, 2021

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• Research PaperVolume 11, Issue 2pp 697-706

  Chronic hyperglycemia regulates microglia polarization through ERK5

  Relevance score: 0.00

  Congde Chen, Suichun Wu, Zipu Hong, Xiaoming Chen, Xiaoou Shan, Shane Fischbach, Xiangwei Xiao

  Keywords: extracellular-signal-regulated kinase 5 (ERK5), diabetes, Alzheimer’s disease (AD), microglia, polarization

  Published in Aging on January 26, 2019

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• Research PaperVolume 17, Issue 5pp 1105-1138

  APOE genotype and biological age impact inter-omic associations related to bioenergetics

  Relevance score: 0.00

  Dylan Ellis, Kengo Watanabe, Tomasz Wilmanski, Michael S. Lustgarten, Andres V. Ardisson Korat, Gwênlyn Glusman, Jennifer Hadlock, Oliver Fiehn, Paola Sebastiani, Nathan D. Price, Leroy Hood, Andrew T. Magis, Simon J. Evans, Lance Pflieger, Jennifer C. Lovejoy, Sean M. Gibbons, Cory C. Funk, Priyanka Baloni, Noa Rappaport

  Keywords: apolipoprotein E (APOE), biological age, metabolism, Alzheimer’s disease (AD), insulin resistance

  Published in Aging on May 3, 2025

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• Research PaperVolume 16, Issue 3pp 1983-2004

  GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects

  Relevance score: 0.00

  Hyun-Hee Park, Hyuk Sung Kwon, Kyu-Yong Lee, Ye Eun Kim, Jeong-Woo Son, Na-Young Choi, Myung-Hoon Han, Dong Woo Park, Sangjae Kim, Seong-Ho Koh

  Keywords: 3xTg-AD mice, GV1001, neurodegeneration, anti-aging, Alzheimer’s disease

  Published in Aging on January 31, 2024

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• Research PaperVolume 17, Issue 11pp 2744-2758

  Topography of small vessel cerebrovascular disease differentially impacts cognitive domains across cognitive syndromes

  Relevance score: 0.00

  Jia Dong James Wang, Yi Jin Leow, Ashwati Vipin, Gurveen Kaur Sandhu, Chao Dang, Seyed Ehsan Saffari, Nagaendran Kandiah

  Keywords: Alzheimer disease, dementia, Asian, cognition, dementia, vascular, cerebrovascular disorders

  Published in Aging on November 17, 2025

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• Research PaperVolume 17, Issue 10pp 2561-2581

  Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis

  Relevance score: 0.00

  Wei Yu Chua, Jia Dong James Wang, Claire Kar Min Chan, Ling-Ling Chan, Eng-King Tan

  Keywords: Alzheimer disease, Dementia, hospitalization, infections, meta-analysis

  Published in Aging on October 13, 2025

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• Research PaperVolume 17, Issue 3pp 726-739

  Sildenafil and risk of Alzheimer disease: a systematic review and meta-analysis

  Relevance score: 0.00

  Wei Yu Chua, Lincoln Kai En Lim, James Jia Dong Wang, Aaron Shengting Mai, Ling-Ling Chan, Eng-King Tan

  Keywords: Alzheimer disease, Sildenafil, meta-analysis, PDE5 inhibitors

  Published in Aging on March 17, 2025

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• Research PaperVolume 13, Issue 20pp 23620-23636

  Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner

  Relevance score: 0.00

  Xiang-Shu Cheng, Fang-Xiao Shi, Kun-Peng Zhao, Wang Lin, Xiao-Ying Li, Jun Zhang, Yao-Yao Bu, Rui Zhu, Xiao-Hong Li, Dong-Xiao Duan, Xin-Ying Ji, Jian-She Wei, Jian-Zhi Wang, Jin Du, Xin-Wen Zhou

  Keywords: Alzheimer disease, nicotinamide mononucleotide adenylyltransferase 2, AMPK, ADAM10, amyloid-β

  Published in Aging on October 13, 2021

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• Research PaperVolume 11, Issue 19pp 8433-8462

  Brain pyrimidine nucleotide synthesis and Alzheimer disease

  Relevance score: 0.00

  Alba Pesini, Eldris Iglesias, M.Pilar Bayona-Bafaluy, Nuria Garrido-Pérez, Patricia Meade, Paula Gaudó, Irene Jiménez-Salvador, Pol Andrés-Benito, Julio Montoya, Isidro Ferrer, Pedro Pesini, Eduardo Ruiz-Pesini

  Keywords: Alzheimer disease, brain, pyrimidine biosynthesis de novo, pyrimidine salvage pathway, oxidative phosphorylation

  Published in Aging on September 27, 2019

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• Research PaperVolume 10, Issue 11pp 3229-3248

  Methanolic extract of Tamarix Gallica attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats

  Relevance score: 0.00

  Maibouge Tanko Mahamane Salissou, Yacoubou Abdoul Razak Mahaman, Feiqi Zhu, Fang Huang, Yuman Wang, Zhendong Xu, Dan Ke, Qun Wang, Rong Liu, Jian-Zhi Wang, Bin Zhang, Xiaochuan Wang

  Keywords: Alzheimer disease, Tamarix Gallica (TG), homocysteine, tau, Amyloid-β (Aβ), cognitive impairments

  Published in Aging on November 12, 2018

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• Research PaperVolume 8, Issue 4pp 664-684

  Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice

  Relevance score: 0.00

  Christian Griñán-Ferré, Sara Sarroca, Aleksandra Ivanova, Dolors Puigoriol-Illamola, Fernando Aguado, Antoni Camins, Coral Sanfeliu, Mercè Pallàs

  Keywords: Alzheimer disease, neurodegeneration, behavior, cognition, deacetylase, methyltransferase

  Published in Aging on March 21, 2016

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• Research PaperVolume 1, Issue 4pp 382-388

  Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

  Relevance score: 0.00

  David J. Bonda, Teresa A. Evans, Corrado Santocanale, Jesús Catalá Llosá, Jose Viňa, Vladan P. Bajic, Rudy J. Castellani, Sandra L. Siedlak, George Perry, Mark A. Smith, Hyoung-gon Lee

  Keywords: Alzheimer disease, cell cycle, DNA replication, minichromosome maintenance protein, neurodegeneration

  Published in Aging on April 23, 2009

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• Research PaperVolume 12, Issue 12pp 12142-12159

  Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice

  Relevance score: 0.00

  Fanlin Zhou, Xiaomin Xiong, Shijie Li, Jie Liang, Xiong Zhang, Mingyuan Tian, Xiaoju Li, Minna Gao, Li Tang, Yu Li

  Keywords: Alzheimer’s disease, dynein intermediate chain, autophagy, axonal transport

  Published in Aging on June 24, 2020

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• Research PaperVolume 12, Issue 10pp 9365-9379

  Association of cerebrospinal fluid neurogranin levels with cognition and neurodegeneration in Alzheimer’s disease

  Relevance score: 0.00

  Mei Xue, Fu-Rong Sun, Ya-Nan Ou, Xue-Ning Shen, Hong-Qi Li, Yu-Yuan Huang, Qiang Dong, Lan Tan, Jin-Tai Yu

  Keywords: Alzheimer’s disease, neurogranin, cerebrospinal fluid, biomarker, mild cognitive impairment

  Published in Aging on May 18, 2020

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• Research PaperVolume 12, Issue 2pp 2005-2017

  Late-life obesity is a protective factor for prodromal Alzheimer’s disease: a longitudinal study

  Relevance score: 0.00

  Zhen Sun, Zuo-Teng Wang, Fu-Rong Sun, Xue-Ning Shen, Wei Xu, Ya-Hui Ma, Qiang Dong, Lan Tan, Jin-Tai Yu

  Keywords: Alzheimer’s disease, body mass index, biomarker, brain volume, cognition

  Published in Aging on January 24, 2020

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