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• Research PaperVolume 17, Issue 7pp 1784-1809

  Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system

  Relevance score: 0.00

  Johanna Ritter, Cassandra Falckenhayn, Minyue Qi, Leonie Gather, Daniel Gutjahr, Johannes Schmidt, Stefan Simm, Stefan Kalkhof, Janosch Hildebrand, Thomas Bosch, Marc Winnefeld, Elke Grönniger, Annette Siracusa

  Keywords: skin rejuvenation, microphysiological systems, systemic factors, bone marrow model, human serum

  Published in Aging on July 25, 2025

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• Research PaperVolume 12, Issue 12pp 12285-12304

  Influences of circulatory factors on intervertebral disc aging phenotype

  Relevance score: 0.00

  Changbin Lei, Debora Colangelo, Prashanti Patil, Vivian Li, Kevin Ngo, Dong Wang, Qing Dong, Matthew J. Yousefzadeh, Hongsheng Lin, Joon Lee, James Kang, Gwendolyn Sowa, Tony Wyss-Coray, Laura J. Niedernhofer, Paul D. Robbins, Derek M. Huffman, Nam Vo

  Keywords: intervertebral disc, heterochronic parabiosis, systemic factors, proteoglycan, aging

  Published in Aging on June 11, 2020

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• Research PaperVolume 16, Issue 10pp 8810-8821

  Systemic immune-inflammation index upon admission correlates to post-stroke cognitive impairment in patients with acute ischemic stroke

  Relevance score: 0.00

  Yongqing Cheng, Honghong Zhu, Changxia Liu, Lei Li, Fangjia Lin, Yan Guo, Cong Gu, Dingming Sun, Yang Gao, Guojun He, Shifu Sun, Shouru Xue

  Keywords: post-stroke cognitive impairment, systemic immune-inflammation index, systemic inflammation response index, acute ischemic stroke, neuroinflammation

  Published in Aging on May 20, 2024

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• Research PaperVolume 11, Issue 13pp 4338-4353

  Targeting HMGB1 by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells

  Relevance score: 0.00

  Juan Ji, Ting Fu, Chen Dong, Wenyan Zhu, Junling Yang, Xiaoli Kong, Zhongyuan Zhang, Yanfeng Bao, Rui Zhao, Xinyu Ge, Xiaoqi Sha, Zhimin Lu, Jing Li, Zhifeng Gu

  Keywords: systemic lupus erythematosus, mesenchymal stem cells, senescence, HMGB1, inflammation

  Published in Aging on July 14, 2019

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• Research PaperVolume 12, Issue 5pp 4357-4370

  Elevated systemic inflammatory responses, factors associated with physical and mental quality of life, and prognosis of hepatocellular carcinoma

  Relevance score: 0.00

  Yang Deng, Jian Zhu, Ziyi Liu, Maosheng Huang, David W. Chang, Jian Gu

  Keywords: hepatocellular carcinoma, quality of life, age at diagnosis, systemic inflammatory response, Short Form-12

  Published in Aging on March 7, 2020

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• Research PaperVolume 18, Issue 1pp 5-28

  Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV

  Relevance score: 0.00

  Alan Tomusiak, Sierra Lore, Morten Scheibye-Knudsen, Eric Verdin

  Keywords: aging, transcriptomic clock, aging biomarkers, systemic aging, intrinsic aging

  Published in Aging on February 8, 2026

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• Research PaperVolume 13, Issue 16pp 20585-20597

  Prognostic and clinicopathological significance of systemic immune-inflammation index in pancreatic cancer: a meta-analysis of 2,365 patients

  Relevance score: 0.00

  Yifang Shui, Mengquan Li, Jing Su, Mingxun Chen, Xiaobin Gu, Wenzhi Guo

  Keywords: meta-analysis, pancreatic cancer, prognosis, biomarker, systemic immune-inflammation index

  Published in Aging on August 25, 2021

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• Research PaperVolume 16, Issue 7pp 6417-6444

  Pan-cancer analysis of Sushi domain-containing protein 4 (SUSD4) and validated in colorectal cancer

  Relevance score: 0.00

  Yuchen Zhong, Chaojing Zheng, Weiyuan Zhang, Hongyu Wu, Qian Zhang, Dechuan Li, Haixing Ju, Haiyang Feng, Yinbo Chen, Yongtian Fan, Weiping Chen, Meng Wang, Guiyu Wang

  Keywords: complement system, systemic pan-cancer analysis, SUSD4, immune infiltration of tumors, prognosis

  Published in Aging on April 4, 2024

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• Research PaperVolume 12, Issue 24pp 25956-25980

  Periodontitis in elderly patients with type 2 diabetes mellitus: impact on gut microbiota and systemic inflammation

  Relevance score: 0.00

  Jinyou Li, Haifeng Lu, Huanwen Wu, Shunmei Huang, Lufang Chen, Qifeng Gui, Wenjing Zhou, Yichen Yang, Yue Wu, Hua Zhang, Qin Zhang, Yunmei Yang

  Keywords: periodontitis, gut microbiota, older individuals, diabetes, systemic inflammation

  Published in Aging on November 25, 2020

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• Research PaperVolume 8, Issue 5pp 1102-1114

  Rapamycin reverses the senescent phenotype and improves immuno-regulation of mesenchymal stem cells from MRL/lpr mice and systemic lupus erythematosus patients through inhibition of the mTOR signaling pathway

  Relevance score: 0.00

  Zhifeng Gu, Wei Tan, Juan Ji, Guijian Feng, Yan Meng, Zhanyun Da, Genkai Guo, Yunfei Xia, Xinhang Zhu, Guixiu Shi, Chun Cheng

  Keywords: rapamycin (RAPA), mesenchymal stem cells (MSCs), systemic lupus erythematosus (SLE), senescence, immunoregulation

  Published in Aging on April 2, 2016

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• EditorialVolume 11, Issue 2pp 301-302

  Mitohormesis and autophagic balance in Parkinson disease

  Relevance score: 0.00

  Diana Luz Juarez-Flores, Ingrid Gonzalez-Casacuberta, Gloria Garrabou

  Keywords: Parkinson disease, mitochondria, autophagy, fibroblasts, systemic disease

  Published in Aging on January 16, 2019

• EditorialVolume 9, Issue 6pp 1471-1472

  Synergistic immunotoxin-paclitaxel combination against lymphoma

  Relevance score: 0.00

  Fabian Müller

  Keywords: immunotoxin, paclitaxel, B-NHL, leukemia, targeted therapy, drug synergy, systemic xenograft model

  Published in Aging on June 13, 2017