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• Research PaperVolume 11, Issue 1pp 185-208

  Rapamycin-mediated mTOR inhibition impairs silencing of sex chromosomes and the pachytene piRNA pathway in the mouse testis

  Relevance score: 0.00

  Zhiping Zhu, Qiuling Yue, Jie Xie, Shuya Zhang, Wenxiu He, Shun Bai, Suwen Tian, Yingwen Zhang, Mengneng Xiong, Zheng Sun, Chaoyang Huang, Yuebei Li, Ke Zheng, Lan Ye

  Keywords: rapamycin, mTOR inhibition, germ cells, meiosis, meiotic silencing of sex chromosomes

  Published in Aging on January 13, 2019

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• Research PerspectiveVolume 15, Issue 14pp 6632-6640

  Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: mTOR, hyperfunction, lifespan, health span, cancer, Alzheimer’s disease

  Published in Aging on July 20, 2023

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• Research PaperVolume 15, Issue 13pp 6152-6162

  Machine learning models predict the mTOR signal pathway-related signature in the gastric cancer involving 2063 samples of 7 centers

  Relevance score: 0.00

  Hao Zhang, Huiqin Zhuo, Jingjing Hou, Jianchun Cai

  Keywords: mTOR, machine learning, cellular senescence, ming classification

  Published in Aging on June 20, 2023

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• Research PaperVolume 13, Issue 6pp 8026-8039

  mTOR inhibition improves mitochondria function/biogenesis and delays cardiovascular aging in kidney transplant recipients with chronic graft dysfunction

  Relevance score: 0.00

  Barbara Infante, Francesco Bellanti, Michele Correale, Paola Pontrelli, Rossana Franzin, Serena Leo, Martina Calvaruso, Silvia Mercuri, Giuseppe Stefano Netti, Elena Ranieri, Natale Daniele Brunetti, Giuseppe Grandaliano, Loreto Gesualdo, Gaetano Serviddio, Giuseppe Castellano, Giovanni Stallone

  Keywords: cardiovascular aging, mTOR inhibitor, kidney transplantation, mitochondria, kidney disease

  Published in Aging on March 23, 2021

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• Research PaperVolume 13, Issue 5pp 7300-7313

  Maf1 suppression of ATF5-dependent mitochondrial unfolded protein response contributes to rapamycin-induced radio-sensitivity in lung cancer cell line A549

  Relevance score: 0.00

  Chen Lai, Jing Zhang, Zhaohua Tan, Liang F. Shen, Rong R. Zhou, Ying Y. Zhang

  Keywords: radio-resistance, non-small cell lung cancer cell, mitochondrial unfolded protein response, mTOR, Maf1

  Published in Aging on February 26, 2021

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• EditorialVolume 12, Issue 14pp 13847-13848

  Cerebrovascular dysfunction links aging to neurological disease

  Relevance score: 0.00

  Candice E. Van Skike, Veronica Galvan

  Keywords: mTOR, aging, Alzheimer’s disease, cerebral blood flow, cerebrovascular dysfunction

  Published in Aging on July 29, 2020

• EditorialVolume 11, Issue 5pp 1331-1332

  mTOR in cerebrovascular disease

  Relevance score: 0.00

  Candice E. Van Skike, Veronica Galvan

  Keywords: mTOR, Alzheimer’s disease, vascular cognitive impairment, atherosclerosis, blood-brain barrier

  Published in Aging on March 13, 2019

• Research PaperVolume 10, Issue 3pp 386-401

  Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice

  Relevance score: 0.00

  Roxanne Weiss, Elizabeth Fernandez, Yuhong Liu, Randy Strong, Adam B. Salmon

  Keywords: mTOR, gluconeogenesis, AMPK, leptin, adiponectin, interventions, insulin

  Published in Aging on March 22, 2018

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• EditorialVolume 9, Issue 12pp 2461-2462

  Towards specific inhibition of mTORC2

  Relevance score: 0.00

  Elizabeth R. Murray, Angus J.M. Cameron

  Keywords: mTOR, mTORC2, AGC kinases, AKT, PKC, Sin1

  Published in Aging on December 12, 2017

• EditorialVolume 8, Issue 3pp 421-422

  Genetics of renal cancer: focus on MTOR

  Relevance score: 0.00

  Arindam P. Ghosh, Sunil Sudarshan

  Keywords: mTOR, rapamycin, renal cancer, mutations

  Published in Aging on March 26, 2016

• EditorialVolume 7, Issue 12pp 1030-1031

  TOR-inhibitors as gero-suppressors

  Relevance score: 0.00

  Mikhail Nikiforov

  Keywords: mTOR, Rapamycin, mTOR inhibitors, gero-suppression

  Published in Aging on December 30, 2015

• Research PerspectiveVolume 6, Issue 12pp 1010-1018

  Gerosuppression in confluent cells

  Relevance score: 0.00

  Olga V. Leontieva, Mikhail V. Blagosklonny

  Keywords: MTOR, rapalogs, sirolimus, aging, cancer, senescence

  Published in Aging on December 31, 2014

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• Research PaperVolume 5, Issue 5pp 339-346

  mTOR pathway and Ca²⁺ stores mobilization in aged smooth muscle cells

  Relevance score: 0.00

  Francisco E. Martín-Cano, Cristina Camello-Almaraz, David Hernandez, Maria J. Pozo, Pedro J. Camello

  Keywords: mTOR, Ca signal²⁺, FKBP12, colon, smooth muscle

  Published in Aging on May 8, 2013

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• HypothesisVolume 5, Issue 4pp 227-233

  Big mice die young but large animals live longer

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: MTOR, rapamycin, aging, geroconversion, gerosuppression

  Published in Aging on April 20, 2013

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• Research PaperVolume 5, Issue 2pp 100-110

  Rapamycin extends life span of Rb1^+/− mice by inhibiting neuroendocrine tumors

  Relevance score: 0.00

  Carolina B. Livi, Rulon L. Hardman, Barbara A. Christy, Sherry G. Dodds, Diane Jones, Charnae Williams, Randy Strong, Alex Bokov, Martin A. Javors, Yuji Ikeno, Gene Hubbard, Paul Hasty, Zelton Dave Sharp

  Keywords: mTOR, rapamycin, Rb1, neuroendocrine tumors

  Published in Aging on February 23, 2013

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• ReviewVolume 4, Issue 12pp 861-877

  Answering the ultimate question “What is the Proximal Cause of Aging?”

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: MTOR, TOR, rapamycin, senescence, cancer, stroke, development, growth

  Published in Aging on December 30, 2012

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• Research PaperVolume 4, Issue 12pp 899-916

  Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging

  Relevance score: 0.00

  Olga V. Leontieva, Geraldine M. Paszkiewicz, Mikhail V. Blagosklonny

  Keywords: MTOR, mTOR Target of rapamycin, growth, aging

  Published in Aging on December 21, 2012

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• Research PaperVolume 4, Issue 10pp 715-722

  New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53^−/− mice by delaying carcinogenesis

  Relevance score: 0.00

  Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski, Olga B. Chernova, Alexander Polinsky, Mikhail V. Blagosklonny, Andrei V. Gudkov, Marina P. Antoch

  Keywords: mTOR pathway, p53−/−, lifespan, rapamycin, oral formulation, cancer prevention

  Published in Aging on October 29, 2012

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• Research PaperVolume 2, Issue 8pp 487-503

  Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage

  Relevance score: 0.00

  Emiliano Panieri, Gabriele Toietta, Marina Mele, Valentina Labate, Sofia Chiatamone Ranieri, Salvatore Fusco, Valentina Tesori, Annalisa Antonini, Giuseppe Maulucci, Marco De Spirito, Tommaso Galeotti, Giovambattista Pani

  Keywords: mTOR, nutrients, cell death, growth factor withdrawal, endothelial cells, ageing

  Published in Aging on August 24, 2010

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• Research PaperVolume 15, Issue 4pp 1210-1227

  Inhibition of apoptosis through AKT-mTOR pathway in ovarian cancer and renal cancer

  Relevance score: 0.00

  Hongrun Chen, Lianfeng Zhang, Meini Zuo, Xiaowen Lou, Bin Liu, Taozhu Fu

  Keywords: Akt-mTOR pathway, renal cancer, ovarian cancer, bioinformatics, verification, biomarker

  Published in Aging on February 27, 2023

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