Volume 5, Issue 4

April 2013pp 227—327

Hypothesis

Big mice die young but large animals live longer

Mikhail V. Blagosklonny

https://doi.org/10.18632/aging.100551pp 227—233

Research Papers

Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis

Vincent R. Richard, Anna Leonov, Adam Beach, Michelle T. Burstein, Olivia Koupaki, Alejandra Gomez-Perez, Sean Levy, Lukas Pluska, Sevan Mattie, Rami Rafeh, Tatiana Iouk, Sara Sheibani, Michael Greenwood, Hojatollah Vali, Vladimir I. Titorenko

https://doi.org/10.18632/aging.100547pp 234—269

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Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner

Sven Brandstädt, Kathrin Schmeisser, Kim Zarse, Michael Ristow

https://doi.org/10.18632/aging.100548pp 270—275

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Autophagy drives epidermal deterioration in a Drosophila model of tissue aging

Christoph Scherfer, Violet C. Han, Yan Wang, Aimee E. Anderson, Michael J. Galko

https://doi.org/10.18632/aging.100549pp 276—287

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An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells

Zheng-Mei Xiong, Christina LaDana, Di Wu, Kan Cao

https://doi.org/10.18632/aging.100550pp 288—303

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IGF1R levels in the brain negatively correlate with longevity in 16 rodent species

Jorge Azpurua, Jiang-Nan Yang, Michael Van Meter, Zhengshan Liu, Julie Kim, Aliny AB Lobo Ladd, Antonio Augusto Coppi, Vera Gorbunova, Andrei Seluanov

https://doi.org/10.18632/aging.100552pp 304—314

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Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila

Julia Hoffmann, Renja Romey, Christine Fink, Li Yong, Thomas Roeder

https://doi.org/10.18632/aging.100553pp 315—327

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