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• Research PaperVolume 11, Issue 2pp 573-589

  Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro

  Relevance score: 0.00

  Zhirui Fan, Lifeng Li, Xiaoli Li, Meng Zhang, Mengmeng Dou, Jing Zhao, Jing Cao, Xiaoming Deng, Mingzhi Zhang, Huixiang Li, Zhenhe Suo

  Keywords: anti-senescence, fumarate hydratase, rat lung fibroblasts

  Published in Aging on January 21, 2019

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• Research PaperVolume 13, Issue 5pp 6890-6903

  MET inhibitor, capmatinib overcomes osimertinib resistance via suppression of MET/Akt/snail signaling in non-small cell lung cancer and decreased generation of cancer-associated fibroblasts

  Relevance score: 0.00

  Kaibin Zhu, Zhonghua Lv, Jinsheng Xiong, Hongshan Zheng, Sibin Zhang, Hua Jin, Lei Yu, Zhenzhe Li, Jixing Zhang, Chenlong Li, Peng Liang

  Keywords: osimertinib resistance, non-small cell lung cancer (NSCLC), cancer-associated fibroblasts (CAFs), MET associated signaling, capmatinib

  Published in Aging on February 17, 2021

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• Research PaperVolume 15, Issue 19pp 10524-10539

  Paroxetine protects against bleomycin-induced pulmonary fibrosis by blocking GRK2/Smad3 pathway

  Relevance score: 0.00

  Kaochang Zhao, Hanxiang Nie, Zheng Tang, Guozhong Chen, Jizhen Huang

  Keywords: pulmonary fibrosis, paroxetine, GRK2, Smad3, lung fibroblasts

  Published in Aging on October 9, 2023

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• Research PaperVolume 16, Issue 9pp 7523-7534

  Cell type-dependent modulation of senescence features using Weo electrolyzed water

  Relevance score: 0.00

  Brenda L. Court-Vazquez, Shirley A. Arroyo-Vizcarrondo, Jonathan A. Poli, Lara Nyman, Kelly Halderman, Anthony Ginter, Pierre-Yves Desprez

  Keywords: cellular senescence, senescence-associated secretory phenotype, oxidative stress, lung fibroblasts, breast cancer cells, senomorphic

  Published in Aging on April 30, 2024

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• Research PaperVolume 15, Issue 11pp 4986-5006

  Development of cancer-associated fibroblast-related gene signature for predicting the survival and immunotherapy response in lung adenocarcinoma

  Relevance score: 0.00

  Yong Zhang, Fuyi Cheng, Jinhu Ma, Gang Shi, Hongxin Deng

  Keywords: lung adenocarcinoma, cancer-associated fibroblasts, immunotherapy, prognosis

  Published in Aging on June 6, 2023

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• Research PaperVolume 13, Issue 7pp 10431-10449

  miR-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the SIRT3/AMPK/mTOR/HIF-1α axis

  Relevance score: 0.00

  Juan Zhang, Lan Han, Jing Yu, Hui Li, Qingfeng Li

  Keywords: cancer-associated fibroblasts, non-small cell lung cancer, miR-224, sirtuin 3, hypoxia-inducible factor-1α

  Published in Aging on April 4, 2021

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• Research PaperVolume 12, Issue 7pp 5812-5831

  Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis

  Relevance score: 0.00

  Qiqing Huang, Yan Chen, Shaoran Shen, Yuanyuan Wang, Liya Liu, Shuangshuang Wu, Wei Xu, Weihong Zhao, Mingyan Lin, Jianqing Wu

  Keywords: idiopathic pulmonary fibrosis (IPF), klotho (KL), weighted gene co-expression network analysis (WGCNA), precision-cut lung slices (PCLSs), pulmonary fibroblasts

  Published in Aging on April 3, 2020

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• Research PaperVolume 16, Issue 21pp 13323-13339

  A differentially-methylated-region signature predicts the recurrence risk for patients with early stage lung adenocarcinoma

  Relevance score: 0.00

  Heng Li, Fuchao Luo, Xiaoran Sun, Chunhua Liao, Guoqiang Wang, Yusheng Han, Leo Li, Chunwei Xu, Wenxian Wang, Shangli Cai, Gao Li, Di Wu

  Keywords: lung adenocarcinoma, DNA methylation, prognosis, recurrence

  Published in Aging on November 18, 2024

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• Research PaperVolume 16, Issue 18pp 12608-12622

  Characterization of a ferroptosis-related gene signature predicting survival and immunotherapeutic response in lung adenocarcinoma

  Relevance score: 0.00

  Chuan Zhang, Yingying Su, Hongrui Wang, Dan Dang, Xin Huang, Shuyou Shi, Yue Shi, Peng Zhang, Ming Yang

  Keywords: lung adenocarcinoma, ferroptosis, prognosis, drug response, gene signature

  Published in Aging on September 18, 2024

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• Research PaperVolume 16, Issue 17pp 12225-12238

  Melatonin downregulates angiogenesis and lymphangiogenesis by regulating tumor-associated macrophages via NLRP3 inflammasomes in lung adenocarcinoma

  Relevance score: 0.00

  Zhewei Zhao, Dongjie Ma, Yingzhi Qin, Yuan Xu, Shanqing Li, Hongsheng Liu

  Keywords: lung adenocarcinoma, tumor microenvironment, angiogenesis and lymphangiogenesis, tumor-associated macrophages, melatonin

  Published in Aging on September 3, 2024

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• EditorialVolume 16, Issue 14pp 11122-11124

  Targeted cancer therapy: the initial high concentration may slow down the selection for resistance

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: lung cancer, resistance, brain metastases, METex14, capmatinib, rapamycin

  Published in Aging on July 28, 2024

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• Research PaperVolume 16, Issue 11pp 10063-10073

  The causal role of immune cells on lung cancer: a bi-directional Mendelian randomization (MR) study

  Relevance score: 0.00

  Hongyu Zhu, Caihua Chen, Haixie Guo, Bo Zhang, Quanteng Hu

  Keywords: lung cancer, immune cells, Mendelian randomization, causality

  Published in Aging on June 12, 2024

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• Research PaperVolume 16, Issue 11pp 9899-9917

  Construction and validation of a prognostic signature based on anoikis-related lncRNAs in lung adenocarcinoma

  Relevance score: 0.00

  Xiaoqi Dong, Chuan Shao, Shuguang Xu, Jinjing Tu, Wenjing Xu, Dahua Chen, Yaodong Tang

  Keywords: lung adenocarcinoma, lncRNAs, anoikis, signature, prognosis

  Published in Aging on June 7, 2024

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• Research PaperVolume 16, Issue 10pp 8747-8771

  Identification of a methyltransferase-related long noncoding RNA signature as a novel prognosis biomarker for lung adenocarcinoma

  Relevance score: 0.00

  Yang Yong Sun, Shuang Li, Chang Liu, Yaqiang Pan, Ying Xiao

  Keywords: lung adenocarcinoma, methyltransferase-related lncRNAs, prognosis, GSEA, immune infiltration

  Published in Aging on May 20, 2024

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• Research PaperVolume 16, Issue 18pp 12498-12509

  SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma

  Relevance score: 0.00

  Guojing Chai, Yingbo Nan, Haili Zhao, Qingchuan Hu

  Keywords: lung adenocarcinoma, SHP2, TAM, STAT3/STAT6 signaling pathway

  Published in Aging on May 14, 2024

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• Research PaperVolume 16, Issue 6pp 5740-5750

  Evaluation of the clinical significance of long non-coding RNA MALAT1 genetic variants in human lung adenocarcinoma

  Relevance score: 0.00

  Shu-Hui Lin, Jeng-Wei Lu, Wang-Ting Hsieh, Ying-Erh Chou, Tzu-Cheng Su, Tun-Jen Tsai, Yun-Jung Tsai, Po-Jen Yang, Shun-Fa Yang

  Keywords: MALAT1, single nucleotide polymorphism, EGFR, lung adenocarcinoma

  Published in Aging on March 21, 2024

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• Research PaperVolume 16, Issue 3pp 2887-2907

  Identification of crucial anoikis-related genes as novel biomarkers and potential therapeutic targets for lung adenocarcinoma via bioinformatic analysis and experimental verification

  Relevance score: 0.00

  Jie Wu, Yuting Zhang, Guoxing You, Wenjie Guo, Yupeng Wang, Jiaming Li, Rongzhi Tan, Xihua Fu, Yukuan Tang, Jie Zan, Jianfen Su

  Keywords: lung adenocarcinoma, anoikis, stratified model, precision medication, immune microenvironment

  Published in Aging on February 9, 2024

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• Research PaperVolume 16, Issue 2pp 1860-1878

  The integration of multi-omics analysis and machine learning for the identification of prognostic assessment and immunotherapy efficacy through aging-associated genes in lung cancer

  Relevance score: 0.00

  Wei Lu, Yun Zhou, Ruixuan Zhao, Qiushi Liu, Wei Yang, Tianyi Zhu

  Keywords: lung cancer, aging, WGCNA, prognostic model, immunotherapy

  Published in Aging on January 22, 2024

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• Research PaperVolume 16, Issue 2pp 1276-1297

  Molecular subgroup establishment and signature creation of lncRNAs associated with acetylation in lung adenocarcinoma

  Relevance score: 0.00

  Hao Chen, Yuanyong Wang, Changjian Shao, Kai Guo, Guanglin Liu, Zhaoyang Wang, Hongtao Duan, Minghong Pan, Peng Ding, Yimeng Zhang, Jing Han, Xiaolong Yan

  Keywords: lung adenocarcinoma, lncRNA, histone acetylation, prognostic signature, immunity

  Published in Aging on January 17, 2024

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• Research PaperVolume 16, Issue 1pp 66-88

  Overexpression of MTFR1 promotes cancer progression and drug-resistance on cisplatin and is related to the immune microenvironment in lung adenocarcinoma

  Relevance score: 0.00

  Qian-Yun Li, Qiang Guo, Wei-Min Luo, Xiang-Yu Luo, Yan-Mei Ji, Li-Qiang Xu, Jia-Long Guo, Rong-Shu Shi, Feng Li, Cheng-Yi Lin, Jun Zhang, Di Ke

  Keywords: lung adenocarcinoma, prognosis, MTFR1, drug resistance, immune infiltration

  Published in Aging on January 2, 2024

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