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• Research PaperVolume 8, Issue 1pp 147-155

  DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age

  Relevance score: 0.00

  Mariëtte E.C. Waaijer, Eleonora Croco, Rudi G.J. Westendorp, P. Eline Slagboom, John M. Sedivy, Antonello Lorenzini, Andrea B. Maier

  Keywords: human aging, 53BP1, telomere-associated foci, micronuclei, biological age

  Published in Aging on January 30, 2016

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• Research PaperVolume 6, Issue 4pp 264-280

  Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cell

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  Arantza Infante, Andrea Gago, Garbiñe Ruiz de Eguino, Teresa Calvo-Fernández, Vanessa Gómez-Vallejo, Jordi Llop, Karin Schlangen, Ane Fullaondo, Ana M. Aransay, Abraham Martín, Clara I. Rodríguez

  Keywords: human mesenchymal stem cells, aging, prelamin A, human aging models, Oct-1, autophagy

  Published in Aging on April 6, 2014

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• Research PaperVolume 8, Issue 5pp 1021-1030

  Deep biomarkers of human aging: Application of deep neural networks to biomarker development

  Relevance score: 0.00

  Evgeny Putin, Polina Mamoshina, Alexander Aliper, Mikhail Korzinkin, Alexey Moskalev, Alexey Kolosov, Alexander Ostrovskiy, Charles Cantor, Jan Vijg, Alex Zhavoronkov

  Keywords: deep learning, deep neural networks, biomarker development, aging biomarkers, human aging, machine learning

  Published in Aging on May 18, 2016

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• Research PaperVolume 5, Issue 1pp 18-36

  Age-associated alterations in inducible gene transcription in human CD4⁺ T lymphocytes

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  Arsun Bektas, Yongqing Zhang, William H. Wood, Kevin G. Becker, Karen Madara, Luigi Ferrucci, Ranjan Sen

  Keywords: human, CD4 T cell⁺, NF-κB, aging, aene expression

  Published in Aging on January 30, 2013

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• Research PaperVolume 15, Issue 11pp 4649-4666

  Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery

  Relevance score: 0.00

  Anatoly Urban, Denis Sidorenko, Diana Zagirova, Ekaterina Kozlova, Aleksandr Kalashnikov, Stefan Pushkov, Vladimir Naumov, Viktoria Sarkisova, Geoffrey Ho Duen Leung, Hoi Wing Leung, Frank W. Pun, Ivan V. Ozerov, Alex Aliper, Feng Ren, Alex Zhavoronkov

  Keywords: transformers, deep learning, therapeutic target discovery, aging biomarkers, human aging

  Published in Aging on June 13, 2023

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• Research PaperVolume 10, Issue 8pp 2190-2208

  Qualitative and quantitative alterations in intracellular and membrane glycoproteins maintain the balance between cellular senescence and human aging

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  Yoko Itakura, Norihiko Sasaki, Masashi Toyoda

  Keywords: cellular senescence, human aging, intracellular glycan, lectin microarray, glycan profile

  Published in Aging on August 29, 2018

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• Research PaperVolume 6, Issue 11pp 957-969

  Age-associated changes in basal NF-κB function in human CD4⁺ T lymphocytes via dysregulation of PI3 kinase

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  Arsun Bektas, Yongqing Zhang, Elin Lehmann, William H. Wood, Kevin G. Becker, Karen Madara, Luigi Ferrucci, Ranjan Sen

  Keywords: CD4+ T cells, NF-κB, PI3K, human aging, gene expression

  Published in Aging on December 6, 2014

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• Research PaperVolume 6, Issue 4pp 296-310

  Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians

  Relevance score: 0.00

  Gianluca Sgarbi, Paola Matarrese, Marcello Pinti, Catia Lanzarini, Barbara Ascione, Lara Gibellini, Emi Dika, Annalisa Patrizi, Chiara Tommasino, Miriam Capri, Andrea Cossarizza, Alessandra Baracca, Giorgio Lenaz, Giancarlo Solaini, Claudio Franceschi, Walter Malorni, Stefano Salvioli

  Keywords: mitochondria, reactive oxygen species, dermal fibroblasts, human aging, longevity, bioenergetics, autophagy, mitophagy

  Published in Aging on April 30, 2014

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• Research PaperVolume 15, Issue 18pp 9293-9309

  Biomedical generative pre-trained based transformer language model for age-related disease target discovery

  Relevance score: 0.00

  Diana Zagirova, Stefan Pushkov, Geoffrey Ho Duen Leung, Bonnie Hei Man Liu, Anatoly Urban, Denis Sidorenko, Aleksandr Kalashnikov, Ekaterina Kozlova, Vladimir Naumov, Frank W. Pun, Ivan V. Ozerov, Alex Aliper, Alex Zhavoronkov

  Keywords: transformers, deep learning, therapeutic target discovery, aging biomarkers, human aging

  Published in Aging on September 22, 2023

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• Research PaperVolume 9, Issue 4pp 1202-1218

  Progressive changes in non-coding RNA profile in leucocytes with age

  Relevance score: 0.00

  Maider Muñoz-Culla, Haritz Irizar, Ana Gorostidi, Ainhoa Alberro, Iñaki Osorio-Querejeta, Javier Ruiz-Martínez, Javier Olascoaga, Adolfo López de Munain, David Otaegui

  Keywords: microRNA, non-coding RNA, transcriptome, regulation, aging, human, leucocytes

  Published in Aging on April 27, 2017

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• Research PaperVolume 10, Issue 9pp 2511-2534

  Identification and characterization of human ovary-derived circular RNAs and their potential roles in ovarian aging

  Relevance score: 0.00

  Hongcai Cai, Yamin Li, Huimin Li, Jean Damascene Niringiyumukiza, Mengdi Zhang, Li Chen, Gang Chen, Wenpei Xiang

  Keywords: human, ovary, circRNA, aging, senescence, granulosa cell

  Published in Aging on September 23, 2018

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• Research PaperVolume 3, Issue 7pp 672-684

  Gene expression profiling suggests a pathological role of human bone marrow-derived mesenchymal stem cells in aging-related skeletal diseases

  Relevance score: 0.00

  Shih Sheng Jiang, Chung-Hsing Chen, Kuo-Yun Tseng, Fang-Yu Tsai, Ming Jen Wang, I-Shou Chang, Jiunn-Liang Lin, Shankung Lin

  Keywords: human bone marrow mesenchymal stem cell, aging, osteoporosis, osteoarthritis

  Published in Aging on July 28, 2011

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• Research PaperVolume 13, Issue 16pp 19978-19995

  TGF-β2 and collagen play pivotal roles in the spheroid formation and anti-aging of human dermal papilla cells

  Relevance score: 0.00

  Hyunju Kim, Nahyun Choi, Doo Yeong Kim, So Yoon Kim, Seung Yong Song, Jong-Hyuk Sung

  Keywords: human dermal papilla cells, aggregation, collagen, TGF-beta2, anti-aging

  Published in Aging on August 17, 2021

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• Research PaperVolume 8, Issue 12pp 3341-3355

  Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human

  Relevance score: 0.00

  Daniele Lettieri-Barbato, Esmeralda Giovannetti, Katia Aquilano

  Keywords: adipose tissue, aging, calorie restriction, fasting, biomarkers, human, longevity

  Published in Aging on November 29, 2016

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• Research PaperVolume 15, Issue 12pp 5240-5265

  Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis

  Relevance score: 0.00

  Jérôme Salignon, Omid R. Faridani, Tasso Miliotis, Georges E. Janssens, Ping Chen, Bader Zarrouki, Rickard Sandberg, Pia Davidsson, Christian G. Riedel

  Keywords: human blood plasma, small RNAs, proteomics, aging, age prediction

  Published in Aging on June 20, 2023

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• Research PaperVolume 8, Issue 3pp 547-560

  Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

  Relevance score: 0.00

  Luke C. Pilling, Janice L. Atkins, Kirsty Bowman, Samuel E. Jones, Jessica Tyrrell, Robin N. Beaumont, Katherine S. Ruth, Marcus A. Tuke, Hanieh Yaghootkar, Andrew R. Wood, Rachel M. Freathy, Anna Murray, Michael N. Weedon, Luting Xue, Kathryn Lunetta, Joanne M. Murabito, Lorna W. Harries, Jean-Marie Robine, Carol Brayne, George A. Kuchel, Luigi Ferrucci, Timothy M. Frayling, David Melzer

  Keywords: aging, longevity, GWAS, genetic, human

  Published in Aging on March 23, 2016

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• Research PaperVolume 14, Issue 22pp 8914-8926

  Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model

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  Kento Takaya, Tatsuyuki Ishii, Toru Asou, Kazuo Kishi

  Keywords: glutaminase inhibitor, human skin, senescent cell, aging, therapeutic agent

  Published in Aging on November 21, 2022

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• EditorialVolume 12, Issue 17pp 16669-16671

  Human skeletal stem cell aging

  Relevance score: 0.00

  Thomas H. Ambrosi, L. Henry Goodnough, Charles K.F. Chan

  Keywords: human skeletal stem cells, geriatric fractures, aging, regeneration, sexual dimorphism

  Published in Aging on September 14, 2020

• ReviewVolume 16, Issue 9pp 8378-8395

  The beginning of becoming a human

  Relevance score: 0.00

  Polina A. Loseva, Vadim N. Gladyshev

  Keywords: human, aging, 14-day rule, life

  Published in Aging on May 6, 2024

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• Research PaperVolume 8, Issue 7pp 1364-1374

  Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study

  Relevance score: 0.00

  Jacob J.E. J.E. Koopman, Jeroen Pijpe, Stefan Böhringer, David van van Bodegom, Ulrika K. K. Eriksson, Hernando Sanchez-Faddeev, Juventus B. B. Ziem, Bas Zwaan, P. Eline Eline Slagboom, Peter de de Knijff, Rudi G.J. G.J. Westendorp

  Keywords: Africa, aging, evolution, fertility, gene, human, life history, SNP, survival

  Published in Aging on June 27, 2016

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