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• Research PaperVolume 12, Issue 9pp 8523-8535

  Computational study of novel natural inhibitors targeting aminopeptidase N(CD13)

  Relevance score: 0.00

  Junliang Ge, Zhongfeng Wang, Ye Cheng, Junan Ren, Bo Wu, Weihang Li, Xinhui Wang, Xing Su, Ziling Liu

  Keywords: cancer, discovery studio, aminopeptidase N(CD13), bestatin

  Published in Aging on May 9, 2020

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• Research PaperVolume 13, Issue 6pp 8248-8275

  Transcriptome profiling reveals target in primary myelofibrosis together with structural biology study on novel natural inhibitors regarding JAK2

  Relevance score: 0.00

  Weihang Li, Bin Yuan, Yingjing Zhao, Tianxing Lu, Shilei Zhang, Ziyi Ding, Dong Wang, Sheng Zhong, Guangxun Gao, Ming Yan

  Keywords: bioinformatics, inhibitor, Janus Kinase 2, virtual screening, discovery studio

  Published in Aging on March 3, 2021

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• Research PaperVolume 15, Issue 18pp 9293-9309

  Biomedical generative pre-trained based transformer language model for age-related disease target discovery

  Relevance score: 0.00

  Diana Zagirova, Stefan Pushkov, Geoffrey Ho Duen Leung, Bonnie Hei Man Liu, Anatoly Urban, Denis Sidorenko, Aleksandr Kalashnikov, Ekaterina Kozlova, Vladimir Naumov, Frank W. Pun, Ivan V. Ozerov, Alex Aliper, Alex Zhavoronkov

  Keywords: transformers, deep learning, therapeutic target discovery, aging biomarkers, human aging

  Published in Aging on September 22, 2023

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• Meeting ReportVolume 10, Issue 11pp 3079-3088

  Aging and drug discovery

  Relevance score: 0.00

  Daniela Bakula, Alexander M. Aliper, Polina Mamoshina, Michael A. Petr, Amanuel Teklu, Joseph A. Baur, Judith Campisi, Collin Y. Ewald, Anastasia Georgievskaya, Vadim N. Gladyshev, Olga Kovalchuk, Dudley W. Lamming, Martijn S. Luijsterburg, Alejandro Martín-Montalvo, Stuart Maudsley, Garik V. Mkrtchyan, Alexey Moskalev, S. Jay Olshansky, Ivan V. Ozerov, Alexander Pickett, Michael Ristow, Alex Zhavoronkov, Morten Scheibye-Knudsen

  Keywords: aging, drug discovery

  Published in Aging on November 13, 2018

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• Meeting ReportVolume 14, Issue 2pp 530-543

  Meeting Report: Aging Research and Drug Discovery

  Relevance score: 0.00

  Esther Meron, Maria Thaysen, Suzanne Angeli, Adam Antebi, Nir Barzilai, Joseph A. Baur, Simon Bekker-Jensen, Maria Birkisdottir, Evelyne Bischof, Jens Bruening, Anne Brunet, Abigail Buchwalter, Filipe Cabreiro, Shiqing Cai, Brian H. Chen, Maria Ermolaeva, Collin Y. Ewald, Luigi Ferrucci, Maria Carolina Florian, Kristen Fortney, Adam Freund, Anastasia Georgievskaya, Vadim N. Gladyshev, David Glass, Tyler Golato, Vera Gorbunova, Jan Hoejimakers, Riekelt H. Houtkooper, Sibylle Jager, Frank Jaksch, Georges Janssens, Martin Borch Jensen, Matt Kaeberlein, Gerard Karsenty, Peter de Keizer, Brian Kennedy, James L. Kirkland, Michael Kjaer, Guido Kroemer, Kai-Fu Lee, Jean-Marc Lemaitre, David Liaskos, Valter D. Longo, Yu-Xuan Lu, Michael R. MacArthur, Andrea B. Maier, Christina Manakanatas, Sarah J. Mitchell, Alexey Moskalev, Laura Niedernhofer, Ivan Ozerov, Linda Partridge, Emmanuelle Passegué, Michael A. Petr, James Peyer, Dina Radenkovic, Thomas A. Rando, Suresh Rattan, Christian G. Riedel, Lenhard Rudolph, Ruixue Ai, Manuel Serrano, Björn Schumacher, David A. Sinclair, Ryan Smith, Yousin Suh, Pam Taub, Alexandre Trapp, Anne-Ulrike Trendelenburg, Dario Riccardo Valenzano, Kris Verburgh, Eric Verdin, Jan Vijg, Rudi G.J. Westendorp, Alessandra Zonari, Daniela Bakula, Alex Zhavoronkov, Morten Scheibye-Knudsen

  Keywords: aging, drug discovery, conference, AI, longevity

  Published in Aging on January 28, 2022

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• Meeting ReportVolume 11, Issue 22pp 9971-9981

  Latest advances in aging research and drug discovery

  Relevance score: 0.00

  Daniela Bakula, Andrea Ablasser, Adriano Aguzzi, Adam Antebi, Nir Barzilai, Martin-Immanuel Bittner, Martin Borch Jensen, Cornelis F. Calkhoven, Danica Chen, Aubrey D.N.J. de Grey, Jerome N. Feige, Anastasia Georgievskaya, Vadim N. Gladyshev, Tyler Golato, Andrei V. Gudkov, Thorsten Hoppe, Matt Kaeberlein, Pekka Katajisto, Brian K. Kennedy, Unmesh Lal, Ana Martin-Villalba, Alexey A. Moskalev, Ivan Ozerov, Michael A. Petr, Reason, David C. Rubinsztein, Alexander Tyshkovskiy, Quentin Vanhaelen, Alex Zhavoronkov, Morten Scheibye-Knudsen

  Keywords: aging, drug discovery, artificial intelligence

  Published in Aging on November 21, 2019

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• Research PaperVolume 15, Issue 8pp 2863-2876

  Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform

  Relevance score: 0.00

  Andrea Olsen, Zachary Harpaz, Christopher Ren, Anastasia Shneyderman, Alexander Veviorskiy, Maria Dralkina, Simon Konnov, Olga Shcheglova, Frank W. Pun, Geoffrey Ho Duen Leung, Hoi Wing Leung, Ivan V. Ozerov, Alex Aliper, Mikhail Korzinkin, Alex Zhavoronkov

  Keywords: aging, target discovery, GBM, glioblastoma, PandaOmics

  Published in Aging on April 26, 2023

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• Research PaperVolume 8, Issue 9pp 2127-2152

  In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state

  Relevance score: 0.00

  Alexander Aliper, Aleksey V. Belikov, Andrew Garazha, Leslie Jellen, Artem Artemov, Maria Suntsova, Alena Ivanova, Larisa Venkova, Nicolas Borisov, Anton Buzdin, Polina Mamoshina, Evgeny Putin, Andrew G. Swick, Alexey Moskalev, Alex Zhavoronkov

  Keywords: geroprotector, drug discovery, screening, drug repurposing, aging

  Published in Aging on September 24, 2016

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• Research PaperVolume 15, Issue 11pp 4649-4666

  Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery

  Relevance score: 0.00

  Anatoly Urban, Denis Sidorenko, Diana Zagirova, Ekaterina Kozlova, Aleksandr Kalashnikov, Stefan Pushkov, Vladimir Naumov, Viktoria Sarkisova, Geoffrey Ho Duen Leung, Hoi Wing Leung, Frank W. Pun, Ivan V. Ozerov, Alex Aliper, Feng Ren, Alex Zhavoronkov

  Keywords: transformers, deep learning, therapeutic target discovery, aging biomarkers, human aging

  Published in Aging on June 13, 2023

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• Research PaperVolume 14, Issue 6pp 2475-2506

  Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine

  Relevance score: 0.00

  Frank W. Pun, Geoffrey Ho Duen Leung, Hoi Wing Leung, Bonnie Hei Man Liu, Xi Long, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evgeny Izumchenko, Alexey Moskalev, João Pedro de Magalhães, Alex Zhavoronkov

  Keywords: artificial intelligence, deep learning, drug discovery, multi-omics, target identification

  Published in Aging on March 29, 2022

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• Meeting ReportVolume 12, Issue 24pp 24484-24503

  ARDD 2020: from aging mechanisms to interventions

  Relevance score: 0.00

  Garik V. Mkrtchyan, Kotb Abdelmohsen, Pénélope Andreux, Ieva Bagdonaite, Nir Barzilai, Søren Brunak, Filipe Cabreiro, Rafael de Cabo, Judith Campisi, Ana Maria Cuervo, Marco Demaria, Collin Y. Ewald, Evandro Fei Fang, Richard Faragher, Luigi Ferrucci, Adam Freund, Carlos G. Silva-García, Anastasia Georgievskaya, Vadim N. Gladyshev, David J. Glass, Vera Gorbunova, Aubrey de Grey, Wei-Wu He, Jan Hoeijmakers, Eva Hoffmann, Steve Horvath, Riekelt H. Houtkooper, Majken K. Jensen, Martin Borch Jensen, Alice Kane, Moustapha Kassem, Peter de Keizer, Brian Kennedy, Gerard Karsenty, Dudley W. Lamming, Kai-Fu Lee, Nanna MacAulay, Polina Mamoshina, Jim Mellon, Marte Molenaars, Alexey Moskalev, Andreas Mund, Laura Niedernhofer, Brenna Osborne, Heidi H. Pak, Andrey Parkhitko, Nuno Raimundo, Thomas A. Rando, Lene Juel Rasmussen, Carolina Reis, Christian G. Riedel, Anais Franco-Romero, Björn Schumacher, David A. Sinclair, Yousin Suh, Pam R. Taub, Debra Toiber, Jonas T. Treebak, Dario Riccardo Valenzano, Eric Verdin, Jan Vijg, Sergey Young, Lei Zhang, Daniela Bakula, Alex Zhavoronkov, Morten Scheibye-Knudsen

  Keywords: aging, interventions, drug discovery, artificial intelligence

  Published in Aging on December 30, 2020

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• Research PaperVolume 12, Issue 1pp 740-755

  Network analysis of human muscle adaptation to aging and contraction

  Relevance score: 0.00

  Craig R.G. Willis, Ryan M. Ames, Colleen S. Deane, Bethan E. Phillips, Catherine L. Boereboom, Haitham Abdulla, Syed S.I. Bukhari, Jonathan N. Lund, John P. Williams, Daniel J. Wilkinson, Kenneth Smith, Fawzi Kadi, Nathaniel J. Szewczyk, Philip J. Atherton, Timothy Etheridge

  Keywords: skeletal muscle, aging, contraction, network analysis, candidate target discovery

  Published in Aging on January 7, 2020

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• Research PaperVolume 8, Issue 9pp 2081-2099

  Age-related hearing loss: prevention of threshold declines, cell loss and apoptosis in spiral ganglion neurons

  Relevance score: 0.00

  Robert D. Frisina, Bo Ding, Xiaoxia Zhu, Joseph P. Walton

  Keywords: aging, neuroscience, hearing loss, drug discovery, auditory system, neurodegeneration

  Published in Aging on September 23, 2016

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