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• Research PaperVolume 15, Issue 23pp 13628-13645

  Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes

  Relevance score: 0.00

  Michaela E. Copp, Jacqueline Shine, Hannon L. Brown, Kirti R. Nimmala, Oliver B. Hansen, Susan Chubinskaya, John A. Collins, Richard F. Loeser, Brian O. Diekman

  Keywords: SIRT6, MDL-800, cartilage, aging, comet assay

  Published in Aging on December 9, 2023

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• Research PaperVolume 13, Issue 5pp 6420-6441

  Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6

  Relevance score: 0.00

  Daniel Stein, Amir Mizrahi, Anastasia Golova, Adam Saretzky, Alfredo Garcia Venzor, Zeev Slobodnik, Shai Kaluski, Monica Einav, Ekaterina Khrameeva, Debra Toiber

  Keywords: SIRT6, YY1, aging, neurodegeneration, transcription regulation

  Published in Aging on March 9, 2021

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• Research PaperVolume 13, Issue 4pp 6025-6040

  SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients

  Relevance score: 0.00

  Jianwei Chen, Zude Liu, Hantao Wang, Lie Qian, Zhanchun Li, Qingxin Song, Guibin Zhong

  Keywords: SIRT6, senescence, DNA damage, telomere dysfunction, telomerase activity

  Published in Aging on February 10, 2021

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• Priority Research PaperVolume 12, Issue 21pp 20946-20967

  Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression

  Relevance score: 0.00

  Ok-Hee Lee, Yun Mi Woo, Sohyeon Moon, Jihyun Lee, Haeun Park, Hoon Jang, Yun-Yong Park, Soo-Kyung Bae, Keun-Hong Park, Ji Hoe Heo, Youngsok Choi

  Keywords: SIRT6, FOXM1, endothelial cell, senescence, cell cycle

  Published in Aging on November 10, 2020

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• Priority Research PaperVolume 12, Issue 18pp 17761-17785

  An ordered assembly of MYH glycosylase, SIRT6 protein deacetylase, and Rad9-Rad1-Hus1 checkpoint clamp at oxidatively damaged telomeres

  Relevance score: 0.00

  Jun Tan, Xiangyu Wang, Bor-Jang Hwang, Rex Gonzales, Olivia Konen, Li Lan, A-Lien Lu

  Keywords: SIRT6, MutY homolog (MYH or MUTYH), checkpoint clamp Rad9/Rad1/Hus1 (9-1-1), DNA damage response, telomeres

  Published in Aging on September 29, 2020

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• Research PaperVolume 12, Issue 17pp 17099-17113

  Sirt6 is required for spermatogenesis in mice

  Relevance score: 0.00

  Huafang Wei, Muhammad Babar Khawar, Wenhao Tang, Lina Wang, Liying Wang, Chao Liu, Hui Jiang, Wei Li

  Keywords: Sirt6, spermatogenesis, elongated spermatid arrest, infertility

  Published in Aging on September 11, 2020

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• Priority Research PaperVolume 12, Issue 12pp 11165-11184

  SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair

  Relevance score: 0.00

  Sarallah Rezazadeh, David Yang, Seyed Ali Biashad, Denis Firsanov, Masaki Takasugi, Michael Gilbert, Gregory Tombline, Natarajan V. Bhanu, Benjamin A. Garcia, Andrei Seluanov, Vera Gorbunova

  Keywords: SIRT6, DNA repair, transcription, genome stability, longevity

  Published in Aging on June 25, 2020

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• Research PaperVolume 10, Issue 8pp 1932-1946

  Sirt6 deficiency impairs corneal epithelial wound healing

  Relevance score: 0.00

  Xiaobing Hu, Shuang Zhu, Rong Liu, Jordan D. Miller, Kevin Merkley, Ronald G. Tilton, Hua Liu

  Keywords: Sirt6, aging, cornea, epithelial wound healing, inflammation

  Published in Aging on August 2, 2018

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• Research PaperVolume 9, Issue 3pp 1069-1083

  Sirt6 deficiency results in progression of glomerular injury in the kidney

  Relevance score: 0.00

  Wen Huang, Hua Liu, Shuang Zhu, Michael Woodson, Rong Liu, Ronald G. Tilton, Jordan D. Miller, Wenbo Zhang

  Keywords: Sirt6, aging, glomerular injury, podocyte

  Published in Aging on March 28, 2017

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• Research PaperVolume 8, Issue 10pp 2308-2323

  SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation

  Relevance score: 0.00

  Ganye Zhao, Hui Wang, Chenzhong Xu, Pan Wang, Jun Chen, Pengfeng Wang, Zhaomeng Sun, Yuanyuan Su, Zhao Wang, Limin Han, Tanjun Tong

  Keywords: SIRT6, p27kip1, acetylation, ubiquitination, cellular senescence

  Published in Aging on September 16, 2016

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• Research PaperVolume 8, Issue 5pp 1064-1078

  SIRT6 protects against endothelial dysfunction and atherosclerosis in mice

  Relevance score: 0.00

  Suowen Xu, Meimei Yin, Marina Koroleva, Michael A. A. Mastrangelo, Wenbo Zhang, Peter Bai, Peter J. J. Little, Zheng Gen Gen Jin

  Keywords: atherosclerosis, endothelial dysfunction, SIRT6, vascular inflammation, RNA-seq

  Published in Aging on May 30, 2016

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• Research PaperVolume 8, Issue 1pp 34-47

  Sirt6 regulates dendritic cell differentiation, maturation, and function

  Relevance score: 0.00

  Denise Lasigliè, Silvia Boero, Inga Bauer, Sara Morando, Patrizia Damonte, Michele Cea, Fiammetta Monacelli, Paizio Odetti, Alberto Ballestrero, Antonio Uccelli, Raul Mostoslavsky, Alessandro Poggi, Alessio Nencioni

  Keywords: Sirt6, dendritic cells, TNF-α, Toll-like receptor ligands, costimulatory molecules, immunosenescence

  Published in Aging on January 12, 2016

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• Research PaperVolume 1, Issue 1pp 109-121

  SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

  Relevance score: 0.00

  Ronald A. McCord, Eriko Michishita, Tao Hong, Elisabeth Berber, Lisa D. Boxer, Rika Kusumoto, Shenheng Guan, Xiaobing Shi, Or Gozani, Alma L. Burlingame, Vilhelm A. Bohr, Katrin F. Chua

  Keywords: Sir2, SIRT6, genomic stability, DNA repair, DNA damage, aging

  Published in Aging on January 15, 2009

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• Research PaperVolume 14, Issue 23pp 9730-9757

  Downregulation of Sirt6 by CD38 promotes cell senescence and aging

  Relevance score: 0.00

  Hongji Zhou, Shihai Liu, NanYang Zhang, Kehua Fang, Jinbao Zong, Yi An, Xiaotian Chang

  Keywords: CD38, cell senescence, aging, D-gal, Sirt6, C3G

  Published in Aging on December 6, 2022

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• Research PaperVolume 13, Issue 9pp 12334-12358

  The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy

  Relevance score: 0.00

  Vinodkumar B. Pillai, Sadhana Samant, Samantha Hund, Madhu Gupta, Mahesh P. Gupta

  Keywords: cardiac aging, Sirt6

  Published in Aging on May 2, 2021

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• ReviewVolume 3, Issue 9pp 829-835

  Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair

  Relevance score: 0.00

  Michael Van Meter, Zhiyong Mao, Vera Gorbunova, Andrei Seluanov

  Keywords: Aging, cancer, SIRT6, DNA repair, PARP1

  Published in Aging on September 22, 2011

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• Research PaperVolume 10, Issue 9pp 2394-2406

  Phosphodiesterase 4 inhibitor activates AMPK-SIRT6 pathway to prevent aging-related adipose deposition induced by metabolic disorder

  Relevance score: 0.00

  Zhuoran Wang, Yaru Liang, Lu Zhang, Nannan Zhang, Qingfei Liu, Zhao Wang

  Keywords: rolipram, aging, adipose deposition, AMPK, SIRT6

  Published in Aging on September 18, 2018

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• Research PaperVolume 11, Issue 10pp 3041-3054

  LncRNA HMMR-AS1 promotes proliferation and metastasis of lung adenocarcinoma by regulating MiR-138/sirt6 axis

  Relevance score: 0.00

  Yong Cai, Zhaoying Sheng, Yun Chen, Jiying Wang

  Keywords: lung adenocarcinoma (LUAD), HMMR-AS1, miR-138, sirt6, proliferation, apoptosis, tumorigenesis

  Published in Aging on May 25, 2019

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• Research PaperVolume 13, Issue 12pp 16381-16403

  Cardiac senescence is alleviated by the natural flavone acacetin via enhancing mitophagy

  Relevance score: 0.00

  Yi-Xiang Hong, Wei-Yin Wu, Fei Song, Chan Wu, Gui-Rong Li, Yan Wang

  Keywords: cardiac senescence, telomere length shortening, mitophagy, Sirt1, Sirt6, pAMPK

  Published in Aging on June 27, 2021

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