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• Research PaperVolume 15, Issue 23pp 13628-13645

  Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes

  Relevance score: 0.00

  Michaela E. Copp, Jacqueline Shine, Hannon L. Brown, Kirti R. Nimmala, Oliver B. Hansen, Susan Chubinskaya, John A. Collins, Richard F. Loeser, Brian O. Diekman

  Keywords: SIRT6, MDL-800, cartilage, aging, comet assay

  Published in Aging on December 9, 2023

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• Research PaperVolume 15, Issue 14pp 6710-6720

  Sirt3 regulates NLRP3 and participates in the effects of plantainoside D on acute lung injury sepsis

  Relevance score: 0.00

  Jing Wang, Wanrong Li, Fang Zhao, Qianqian Han, Lingling Shan, Yumei Qian

  Keywords: sirt3, NLRP3, sepsis, ALI

  Published in Aging on April 5, 2023

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• Research PaperVolume 13, Issue 20pp 23652-23671

  Up-regulation of SIRT1 induced by 17beta-estradiol promotes autophagy and inhibits apoptosis in osteoblasts

  Relevance score: 0.00

  Yu Wang, Runhong Mei, Shimin Hao, Peng Luo, Penghao Wang, Yaser Almatari, Lei Guo, Lan Guo

  Keywords: SIRT1, autophagy, apoptosis, AMPK-mTOR, FOXO3a

  Published in Aging on October 28, 2021

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• Research PaperVolume 13, Issue 11pp 15479-15490

  Myeloid-specific SIRT1 deletion exacerbates airway inflammatory response in a mouse model of allergic asthma

  Relevance score: 0.00

  Tianwen Lai, Guomei Su, Dong Wu, Ziyu Chen, Yujuan Chen, Huajuan Yi, Yun Gao, Cuifen Chen, Man Zeng, Min Chen, Dongming Li, Bin Wu

  Keywords: SIRT1, asthma, BMDM, macrophage

  Published in Aging on June 7, 2021

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• Research PaperVolume 13, Issue 9pp 12334-12358

  The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy

  Relevance score: 0.00

  Vinodkumar B. Pillai, Sadhana Samant, Samantha Hund, Madhu Gupta, Mahesh P. Gupta

  Keywords: cardiac aging, Sirt6

  Published in Aging on May 2, 2021

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• Research PaperVolume 13, Issue 9pp 12308-12333

  Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1

  Relevance score: 0.00

  Alfredo Martínez-Gutiérrez, Irene Fernández-Duran, Anna Marazuela-Duque, Nicolás G. Simonet, Ibraheem Yousef, Immaculada Martínez-Rovira, Josefina Martínez-Hoyos, Alejandro Vaquero

  Keywords: SIRT1, senescence, human dermal fibroblasts, UV irradiation, shikimic acid

  Published in Aging on April 26, 2021

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• Research PaperVolume 13, Issue 5pp 6420-6441

  Aging and pathological aging signatures of the brain: through the focusing lens of SIRT6

  Relevance score: 0.00

  Daniel Stein, Amir Mizrahi, Anastasia Golova, Adam Saretzky, Alfredo Garcia Venzor, Zeev Slobodnik, Shai Kaluski, Monica Einav, Ekaterina Khrameeva, Debra Toiber

  Keywords: SIRT6, YY1, aging, neurodegeneration, transcription regulation

  Published in Aging on March 9, 2021

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• Research PaperVolume 13, Issue 4pp 6025-6040

  SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients

  Relevance score: 0.00

  Jianwei Chen, Zude Liu, Hantao Wang, Lie Qian, Zhanchun Li, Qingxin Song, Guibin Zhong

  Keywords: SIRT6, senescence, DNA damage, telomere dysfunction, telomerase activity

  Published in Aging on February 10, 2021

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• Research PaperVolume 13, Issue 10pp 14482-14498

  Sirt1 improves heart failure through modulating the NF-κB p65/microRNA-155/BNDF signaling cascade

  Relevance score: 0.00

  Bin Lin, Hui Zhao, Li Li, Zhenzhen Zhang, Nan Jiang, Xiaowei Yang, Tao Zhang, Bowen Lian, Yaokai Liu, Chi Zhang, Jiaxiang Wang, Feng Wang, Deguang Feng, Jing Xu

  Keywords: heart failure, Sirt1, NF-κB p65, microRNA-155, BDNF

  Published in Aging on November 18, 2020

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• Priority Research PaperVolume 12, Issue 21pp 20946-20967

  Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression

  Relevance score: 0.00

  Ok-Hee Lee, Yun Mi Woo, Sohyeon Moon, Jihyun Lee, Haeun Park, Hoon Jang, Yun-Yong Park, Soo-Kyung Bae, Keun-Hong Park, Ji Hoe Heo, Youngsok Choi

  Keywords: SIRT6, FOXM1, endothelial cell, senescence, cell cycle

  Published in Aging on November 10, 2020

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• Research PaperVolume 12, Issue 19pp 18942-18956

  Activation of LKB1 rescues 3T3-L1 adipocytes from senescence induced by Sirt1 knock-down: a pivotal role of LKB1 in cellular aging

  Relevance score: 0.00

  Fan Lan, Yan Lin, Zhenfeng Gao, Jose M. Cacicedo, Karen Weikel, Yasuo Ido

  Keywords: Sirt1, LKB1, AMPK, adipocytes, aging

  Published in Aging on October 10, 2020

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• Priority Research PaperVolume 12, Issue 18pp 17761-17785

  An ordered assembly of MYH glycosylase, SIRT6 protein deacetylase, and Rad9-Rad1-Hus1 checkpoint clamp at oxidatively damaged telomeres

  Relevance score: 0.00

  Jun Tan, Xiangyu Wang, Bor-Jang Hwang, Rex Gonzales, Olivia Konen, Li Lan, A-Lien Lu

  Keywords: SIRT6, MutY homolog (MYH or MUTYH), checkpoint clamp Rad9/Rad1/Hus1 (9-1-1), DNA damage response, telomeres

  Published in Aging on September 29, 2020

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• Research PaperVolume 12, Issue 18pp 17990-18007

  SIRT1 activation by minocycline on regulation of microglial polarization homeostasis

  Relevance score: 0.00

  Ling-Hsuan Wu, Bor-Ren Huang, Sheng-Wei Lai, Chingju Lin, Hsiao-Yun Lin, Liang-Yo Yang, Dah-Yuu Lu

  Keywords: microglia, SIRT1, minocycline, microglial polarization, acetyl-p53

  Published in Aging on September 23, 2020

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• Research PaperVolume 12, Issue 17pp 17099-17113

  Sirt6 is required for spermatogenesis in mice

  Relevance score: 0.00

  Huafang Wei, Muhammad Babar Khawar, Wenhao Tang, Lina Wang, Liying Wang, Chao Liu, Hui Jiang, Wei Li

  Keywords: Sirt6, spermatogenesis, elongated spermatid arrest, infertility

  Published in Aging on September 11, 2020

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• Research PaperVolume 12, Issue 16pp 16224-16237

  SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury

  Relevance score: 0.00

  Ting Xin, Chengzhi Lu

  Keywords: SirT3, AMPK, septic cardiomyopathy, mitochondrial biogenesis

  Published in Aging on July 28, 2020

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• Research PaperVolume 12, Issue 16pp 16126-16141

  SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy

  Relevance score: 0.00

  Yiyang Wang, Haoming Wang, Yunyun Zhuo, Yanzhu Hu, Zetong Zhang, Jixing Ye, Liehua Liu, Lei Luo, Chen Zhao, Qiang Zhou, Pei Li

  Keywords: SIRT1, compression, senescence, nucleus pulposus, mitophagy

  Published in Aging on July 18, 2020

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• Priority Research PaperVolume 12, Issue 12pp 11165-11184

  SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair

  Relevance score: 0.00

  Sarallah Rezazadeh, David Yang, Seyed Ali Biashad, Denis Firsanov, Masaki Takasugi, Michael Gilbert, Gregory Tombline, Natarajan V. Bhanu, Benjamin A. Garcia, Andrei Seluanov, Vera Gorbunova

  Keywords: SIRT6, DNA repair, transcription, genome stability, longevity

  Published in Aging on June 25, 2020

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• Research PaperVolume 12, Issue 12pp 11364-11385

  Sirt1 gene confers Adriamycin resistance in DLBCL via activating the PCG-1α mitochondrial metabolic pathway

  Relevance score: 0.00

  Zhen Zhou, Dan Ma, Peifan Li, Ping Wang, Ping Liu, Danna Wei, Jun Wang, Zhong Qin, Qin Fang, Jishi Wang

  Keywords: DLBCL, chemotherapy resistance, Adriamycin, Sirt1, PCG-1α

  Published in Aging on June 22, 2020

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• Research PaperVolume 12, Issue 8pp 7431-7447

  Sirt1 is regulated by miR-135a and involved in DNA damage repair during mouse cellular reprogramming

  Relevance score: 0.00

  Andy Chun Hang Chen, Qian Peng, Sze Wan Fong, William Shu Biu Yeung, Yin Lau Lee

  Keywords: mouse induced pluripotent stem cells, cellular reprogramming, Sirt1, miR-135a, DNA damage repair

  Published in Aging on April 26, 2020

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• Research PaperVolume 12, Issue 8pp 7042-7055

  SIRT1 regulates O-GlcNAcylation of tau through OGT

  Relevance score: 0.00

  Shu Lu, Xiaomin Yin, Jia Wang, Qun Gu, Qin Huang, Nana Jin, Dandan Chu, Ziqi Xu, Fei Liu, Wei Qian

  Keywords: SIRT1, OGT, O-GlcNAcylation of tau, phosphorylation of tau, Alzheimer’s disease

  Published in Aging on April 20, 2020

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