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The cover features Figure 2 "TERRA expression in murine oocytes, early cleavage and blastocyst stage with regards to maternal age“ from Kordowitzki et al.

Volume 12, Issue 16

31 August, 2020
pp 15875—16664

About the Cover

The cover features Figure 2 "TERRA expression in murine oocytes, early cleavage and blastocyst stage with regards to maternal age“ from Kordowitzki et al.


Explore This Issue

Editorials

Aging without inflammaging: lesson from Spalax

Irena Manov, Amani Odeh, Imad Shams,
https://doi.org/10.18632/aging.103953 pp 15875—15877
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Bacterial taxa decoupling with ageing

Andrés Moya, Susana Ruiz-Ruiz, Manuel Ferrer,
https://doi.org/10.18632/aging.104031 pp 15878—15879
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Muscle phosphorus metabolites in sarcopenia

J. Matthew Hinkley, Paul M. Coen,
https://doi.org/10.18632/aging.104032 pp 15880—15881
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Priority Research Papers

Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis

Marta Varela-Eirín, Paula Carpintero-Fernández, Agustín Sánchez-Temprano, Adrián Varela-Vázquez, Carlos Luis Paíno, Antonio Casado-Díaz, Alfonso Calañas-Continente, Virginia Mato, Eduardo Fonseca, Mustapha Kandouz, Alfonso Blanco, José Ramón Caeiro, María D. Mayán,
https://doi.org/10.18632/aging.103801 pp 15882—15905
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Dynamics of telomeric repeat-containing RNA expression in early embryonic cleavage stages with regards to maternal age

Paweł Kordowitzki, Isabel López de Silanes, Ana Guío-Carrión, Maria A. Blasco,
https://doi.org/10.18632/aging.103922 pp 15906—15917
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Research Papers

COVID-19
Early coagulation tests predict risk stratification and prognosis of COVID-19

Lili Luo, Min Xu, Mengyi Du, Haiming Kou, Danying Liao, Zhipeng Cheng, Heng Mei, Yu Hu,
https://doi.org/10.18632/aging.103581 pp 15918—15937
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COVID-19
Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China

Chaowei Li, Qingshi Chen, Jianwen Wang, Huasong Lin, Yalan Lin, Jinhuang Lin, Fangzhan Peng, Jiangmu Chen, Zhirong Yang,
https://doi.org/10.18632/aging.103632 pp 15938—15945
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COVID-19
Clinical course and characteristics of patients with coronavirus disease 2019 in Wuhan, China: a single-centered, retrospective, observational study

Yanfang Liu, Lina Liu, Ye Wang, Xinyang Du, Hong Ma, Jing Yao,
https://doi.org/10.18632/aging.103745 pp 15946—15953
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COVID-19
COVID-19: a probable role of the anticoagulant Protein S in managing COVID-19-associated coagulopathy

Sabyasachi Chatterjee, Tanusree Sengupta, Samarpan Majumder, Rinku Majumder,
https://doi.org/10.18632/aging.103869 pp 15954—15961
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Genetic variation between long-lived versus short-lived bats illuminates the molecular signatures of longevity

Zixia Huang, Conor V. Whelan, Dina Dechmann, Emma C. Teeling,
https://doi.org/10.18632/aging.103725 pp 15962—15977
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A human MMTV-like betaretrovirus linked to breast cancer has been present in humans at least since the copper age

Francesca Lessi, Nicole Grandi, Chiara Maria Mazzanti, Prospero Civita, Cristian Scatena, Paolo Aretini, Pasquale Bandiera, Antonio Fornaciari, Valentina Giuffra, Gino Fornaciari, Antonio Giuseppe Naccarato, Enzo Tramontano, Generoso Bevilacqua,
https://doi.org/10.18632/aging.103780 pp 15978—15994
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Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer’s disease: a pre-clinical study

Valentina Cecarini, Laura Bonfili, Olee Gogoi, Solomon Lawrence, Franco M. Venanzi, Vasco Azevedo, Pamela Mancha-Agresti, Mariana Martins Drumond, Giacomo Rossi, Sara Berardi, Livio Galosi, Massimiliano Cuccioloni, Mauro Angeletti, Jan S. Suchodolski, Rachel Pilla, Jonathan A. Lidbury, Anna Maria Eleuteri,
https://doi.org/10.18632/aging.103900 pp 15995—16020
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Long non-coding RNA DLX6-AS1 facilitates bladder cancer progression through modulating miR-195-5p/VEGFA signaling pathway

Hengbing Wang, Xiaobing Niu, Hesong Jiang, Fei Mao, Bing Zhong, Xi Jiang, Guangbo Fu,
https://doi.org/10.18632/aging.103374 pp 16021—16034
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Systems biology approach to exploring the effect of cyclic stretching on cardiac cell physiology

Chien-Cheng Chen, Tzyy-Yue Wong, Tzu-Yun Chin, Wen-Hsien Lee, Chan-Yen Kuo, Yi-Chiung Hsu,
https://doi.org/10.18632/aging.103465 pp 16035—16045
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Pan-metastatic cancer analysis of prognostic factors and a prognosis-based metastatic cancer classification system

Chao Zhang, Guijun Xu, Yao Xu, Haixiao Wu, Xu Guo, Min Mao, Vladimir P. Baklaushev, Vladimir P. Chekhonin, Karl Peltzer, Ye Bai, Guowen Wang, Wenjuan Ma, Xin Wang,
https://doi.org/10.18632/aging.103467 pp 16046—16061
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Synergistic effect of electric stimulation and mesenchymal stem cells against Parkinson's disease

Chunhui Yang, Yiqing Qiu, Yuan Qing, Jinyu Xu, Wei Dai, Xiaowu Hu, Xi Wu,
https://doi.org/10.18632/aging.103477 pp 16062—16071
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Controlled attenuation parameter value-based diagnostic algorithm improves the accuracy of liver stiffness measurement in chronic hepatitis B patients

Yaoxin Fan, Lin Wang, Yang Ding, Qiuju Sheng, Chong Zhang, Yanwei Li, Chao Han, Xiaoguang Dou,
https://doi.org/10.18632/aging.103522 pp 16072—16082
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Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia

Yi-Lin Kong, Bi-Hui Pan, Jin-Hua Liang, Hua-Yuan Zhu, Li Wang, Yi Xia, Jia-Zhu Wu, Lei Fan, Jian-Yong Li, Wei Xu,
https://doi.org/10.18632/aging.103536 pp 16083—16098
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IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease

Mu Wang, Jian Guo, Yi-Qing Zhao, Jun-Ping Wang,
https://doi.org/10.18632/aging.103566 pp 16099—16110
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Testosterone ameliorates vascular aging via the Gas6/Axl signaling pathway

Yan-Qing Chen, Hui-Min Zhou, Fang-Fang Chen, Ya-Peng Liu, Lu Han, Ming Song, Zhi-Hao Wang, Wei Zhang, Yuan-Yuan Shang, Ming Zhong,
https://doi.org/10.18632/aging.103584 pp 16111—16125
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SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy

Yiyang Wang, Haoming Wang, Yunyun Zhuo, Yanzhu Hu, Zetong Zhang, Jixing Ye, Liehua Liu, Lei Luo, Chen Zhao, Qiang Zhou, Pei Li,
https://doi.org/10.18632/aging.103587 pp 16126—16141
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LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway

Yan Liu, Li Ma, Fugen Shangguan, Xuena Zhao, Wenjie Wang, Zhiyue Gao, Huimin Zhou, Guiwu Qu, Yumei Huang, Jing An, Jiangnan Xue, Shude Yang, Qizhi Cao,
https://doi.org/10.18632/aging.103589 pp 16142—16154
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RPP30, a transcriptional regulator, is a potential pathogenic factor in glioblastoma

Guanzhang Li, You Zhai, Hanjie Liu, Zhiliang Wang, Ruoyu Huang, Haoyu Jiang, Yuemei Feng, Yuanhao Chang, Fan Wu, Fan Zeng, Tao Jiang, Wei Zhang,
https://doi.org/10.18632/aging.103596 pp 16155—16171
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Leptin promotes bone metastasis of breast cancer by activating the SDF-1/CXCR4 axis

Lixia Duan, Yongkui Lu, Weimin Xie, Li Nong, Yuxian Jia, Aihua Tan, Yan Liu,
https://doi.org/10.18632/aging.103599 pp 16172—16182
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Differential functional dysconnectivity of caudate nucleus subdivisions in Parkinson’s disease

Xiuqin Jia, Zhenyu Pan, Huimin Chen, Zhijiang Wang, Kun Li, Xuemei Wang, Zhan Wang, Huizi Ma, Tao Feng, Qi Yang,
https://doi.org/10.18632/aging.103628 pp 16183—16194
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Cortical aging – new insights with multiparametric quantitative MRI

Alexander Seiler, Sophie Schöngrundner, Benjamin Stock, Ulrike Nöth, Elke Hattingen, Helmuth Steinmetz, Johannes C. Klein, Simon Baudrexel, Marlies Wagner, Ralf Deichmann, René-Maxime Gracien,
https://doi.org/10.18632/aging.103629 pp 16195—16210
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Mst1 promotes mitochondrial dysfunction and apoptosis in oxidative stress-induced rheumatoid arthritis synoviocytes

Yingjie Wang, Qi Yang, Songpo Shen, Linjie Zhang, Yongbo Xiang, Xisheng Weng,
https://doi.org/10.18632/aging.103643 pp 16211—16223
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SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury

Ting Xin, Chengzhi Lu,
https://doi.org/10.18632/aging.103644 pp 16224—16237
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Prognostic values of GPNMB identified by mining TCGA database and STAD microenvironment

Kunhou Yao, Lunshou Wei, Junjie Zhang, Chenyu Wang, Chaoyang Wang, Changjiang Qin, Song Li,
https://doi.org/10.18632/aging.103646 pp 16238—16254
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Glucose and cholesterol induce abnormal cell divisions via DAF-12 and MPK-1 in C. elegans

Zhi Qu, Shaoping Ji, Shanqing Zheng,
https://doi.org/10.18632/aging.103647 pp 16255—16269
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CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis

Qiuhua Lai, Qingyuan Li, Chengcheng He, Yuxin Fang, Simin Lin, Jianqun Cai, Jian Ding, Qian Zhong, Yue Zhang, Changjie Wu, Xinke Wang, Juan He, Yongfeng Liu, Qun Yan, Aimin Li, Side Liu,
https://doi.org/10.18632/aging.103648 pp 16270—16293
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Circulating exosomal miR-144-3p inhibits the mobilization of endothelial progenitor cells post myocardial infarction via regulating the MMP9 pathway

Yihai Liu, Jiamin Xu, Rong Gu, Zhu Li, Kun Wang, Yu Qi, Xuan Sun, Jun Xie, Lian Wang, Biao Xu, Lina Kang,
https://doi.org/10.18632/aging.103651 pp 16294—16303
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SP1-induced HOXD-AS1 promotes malignant progression of cholangiocarcinoma by regulating miR-520c-3p/MYCN

Jinglin Li, Xingming Jiang, Zhenglong Li, Lining Huang, Daolin Ji, Liang Yu, Yongxu Zhou, Yunfu Cui,
https://doi.org/10.18632/aging.103660 pp 16304—16325
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PTEN participates in airway remodeling of asthma by regulating CD38/Ca2+/CREB signaling

Yuanyuan Wu, Yiyi Lu, Fan Zou, Xinping Fan, Xudong Li, Hongni Zhang, Haijuan Chen, Xiuzhen Sun, Yun Liu,
https://doi.org/10.18632/aging.103664 pp 16326—16340
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Abnormal static and dynamic functional connectivity of resting-state fMRI in multiple system atrophy

Weimin Zheng, Yunxiang Ge, Shan Ren, Weizheng Ran, Xinning Zhang, Wenyang Tian, Zhigang Chen, Weibei Dou, Zhiqun Wang,
https://doi.org/10.18632/aging.103676 pp 16341—16356
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Association between Nrf2 and CDKN2A expression in patients with end-stage renal disease: a pilot study

Keiichi Sumida, Zhongji Han, Ankur A. Dashputre, Praveen K. Potukuchi, Csaba P. Kovesdy,
https://doi.org/10.18632/aging.103685 pp 16357—16367
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Flavonoids from Rosa roxburghii Tratt prevent reactive oxygen species-mediated DNA damage in thymus cells both combined with and without PARP-1 expression after exposure to radiation in vivo

Sai-Juan Xu, Xia Wang, Tao-Yang Wang, Zheng-Zhan Lin, Yong-Jian Hu, Zhong-Lin Huang, Xian-Jun Yang, Ping Xu,
https://doi.org/10.18632/aging.103688 pp 16368—16389
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PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells

Xiangru Zheng, Jinlai Wei, Wenjun Li, Xiaoli Li, Wuyi Wang, Jinbao Guo, Zhongxue Fu,
https://doi.org/10.18632/aging.103690 pp 16390—16409
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The association of serum vitamin K2 levels with Parkinson's disease: from basic case-control study to big data mining analysis

Yan-Xia Yu, Xiao-Dan Yu, Qin-zhang Cheng, Lian Tang, Ming-Qiang Shen,
https://doi.org/10.18632/aging.103691 pp 16410—16419
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Prognostic value and underlying mechanism of KIAA0101 in hepatocellular carcinoma: database mining and co-expression analysis

Weiyu Xu, Xuezhu Wang, Xiaoqian Wu, Si Yu, Jianping Xiong, Xinting Sang, Yongchang Zheng, Zhongtao Zhang,
https://doi.org/10.18632/aging.103704 pp 16420—16436
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KCNN4 is a diagnostic and prognostic biomarker that promotes papillary thyroid cancer progression

Jialiang Wen, Bangyi Lin, Lizhi Lin, Yizuo Chen, Ouchen Wang,
https://doi.org/10.18632/aging.103710 pp 16437—16456
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Risk stratification of cutaneous melanoma reveals carcinogen metabolism enrichment and immune inhibition in high-risk patients

Xia Li, Yunpeng Cai,
https://doi.org/10.18632/aging.103734 pp 16457—16475
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Relationship closeness buffers the effects of perceived stress on transcriptomic indicators of cellular stress and biological aging marker p16INK4a

Kelly E. Rentscher, Judith E. Carroll, Steve W. Cole, Rena L. Repetti, Theodore F. Robles,
https://doi.org/10.18632/aging.103739 pp 16476—16490
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Eight immune-related genes predict survival outcomes and immune characteristics in breast cancer

Han Xu, Gangjian Wang, Lili Zhu, Hong Liu, Bingjie Li,
https://doi.org/10.18632/aging.103753 pp 16491—16513
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Coupled immune stratification and identification of therapeutic candidates in patients with lung adenocarcinoma

Weilei Hu, Guosheng Wang, Yundi Chen, Lonny B. Yarmus, Biao Liu, Yuan Wan,
https://doi.org/10.18632/aging.103775 pp 16514—16538
View Abstract PDF Full-Text How to Cite Special Collection on Cancer Therapeutics

Accelerated epigenetic aging as a risk factor for chronic obstructive pulmonary disease and decreased lung function in two prospective cohort studies

Miyuki Breen, Jamaji C. Nwanaji-Enwerem, Stefan Karrasch, Claudia Flexeder, Holger Schulz, Melanie Waldenberger, Sonja Kunze, Markus Ollert, Stefan Weidinger, Elena Colicino, Xu Gao, Cuicui Wang, Jincheng Shen, Allan C. Just, Pantel Vokonas, David Sparrow, Lifang Hou, Joel D. Schwartz, Andrea A. Baccarelli, Annette Peters, Cavin K. Ward-Caviness,
https://doi.org/10.18632/aging.103784 pp 16539—16554
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Prognostic model of patients with liver cancer based on tumor stem cell content and immune process

Weikaixin Kong, Miaomiao Gao, Yuchen Jin, Weiran Huang, Zhuo Huang, Zhengwei Xie,
https://doi.org/10.18632/aging.103832 pp 16555—16578
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Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury

Jing-Yao Song, Bin Fan, Lin Che, Yi-Ran Pan, Si-Ming Zhang, Ying Wang, Victoria Bunik, Guang-Yu Li,
https://doi.org/10.18632/aging.103846 pp 16579—16596
View Abstract PDF Full-Text How to Cite Special Collection on Eye Disease

Balloon aortic valvuloplasty as a palliative treatment in patients with severe aortic stenosis and limited life expectancy: a single center experience

Francesca Mantovani, Marie-Annick Clavel, Antonella Potenza, Chiara Leuzzi, Teresa Grimaldi, Luigi Vignali, Alessandro Navazio, Vincenzo Guiducci,
https://doi.org/10.18632/aging.103862 pp 16597—16608
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Autoantibodies against M5-muscarinic and beta1-adrenergic receptors in periodontitis patients

Isabel Scherbaum, Harald Heidecke, Kübra Bunte, Ulrike Peters, Thomas Beikler, Fritz Boege,
https://doi.org/10.18632/aging.103864 pp 16609—16620
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Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype

Xiangyong Li, Qian Zhou, Shuangshuang Wang, Ping Wang, Juan Li, Zhiwei Xie, Chang Liu, Jie Wen, Xunwei Wu,
https://doi.org/10.18632/aging.103910 pp 16621—16646
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Review

ATP synthase and Alzheimer’s disease: putting a spin on the mitochondrial hypothesis

Brad Ebanks, Thomas L Ingram, Lisa Chakrabarti,
https://doi.org/10.18632/aging.103867 pp 16647—16662
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Correction

Correction for: Swimming exercise stimulates IGF1/PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

Jing-Ying Lin, Wei-Wen Kuo, Rathinasamy Baskaran, Chia-Hua Kuo, Yun-An Chen, William Shao-Tsu Chen, Tsung-Jung Ho, Cecilia Hsuan Day, B. Mahalakshmi, Chih-Yang Huang,
https://doi.org/10.18632/aging.104045 pp 16663—16664
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