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• Research PaperVolume 17, Issue 11pp 2688-2716

  SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells

  Relevance score: 0.00

  Ryan Wallis, Bethany K. Hughes, Madeleine Moore, Emily A. O’Sullivan, Luke C. McIlvenna, Luke Gammon, Anthony Hope, Fiona Bellany, Parul Dixit, Claire Mackenzie, Charlotte Green, David Gray, Cleo L. Bishop

  Keywords: SAMP-Score, senescence, senescent marker positive cancer cells, Sen-Mark+, machine learning, pro-senescence, high-throughput compound screening

  Published in Aging on October 30, 2025

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• Research PaperVolume 13, Issue 11pp 14829-14842

  Effect of samul-tang on female fertility via RAS signaling pathway in ovaries of aged mice

  Relevance score: 0.00

  Jihyun Kim, Sooseong You

  Keywords: aging, samul-tang, ovarian reserve, pregnancy, mice

  Published in Aging on June 6, 2021

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• Research PaperVolume 10, Issue 9pp 2338-2355

  Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice

  Relevance score: 0.00

  Soo-A Kim, Thuy Giang Lam, Jong-In Yook, Sang-Gun Ahn

  Keywords: SAMP1/ Klotho, aging, metabolic profiling, HL156A, antioxidant, glutathione

  Published in Aging on September 16, 2018

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• Research PaperVolume 13, Issue 2pp 2015-2030

  Mendelian randomization study of telomere length and bone mineral density

  Relevance score: 0.00

  Fashuai Wu, Yu Huang, Jialu Hu, Zengwu Shao

  Keywords: two-sample Mendelian randomization, telomere length, bone mineral density, osteoporosis

  Published in Aging on December 15, 2020

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• Research PaperVolume 14, Issue 10pp 4220-4246

  Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence

  Relevance score: 0.00

  Ryan Wallis, Deborah Milligan, Bethany Hughes, Hannah Mizen, José Alberto López-Domínguez, Ugochim Eduputa, Eleanor J. Tyler, Manuel Serrano, Cleo L. Bishop

  Keywords: senescence, high content profiling of senescence hallmarks, morphology, senescence-associated morphological profiles (SAMPs)

  Published in Aging on May 16, 2022

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• Research PaperVolume 10, Issue 6pp 1257-1267

  Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

  Relevance score: 0.00

  Gaofeng Zhan, Ning Yang, Shan Li, Niannian Huang, Xi Fang, Jie Zhang, Bin Zhu, Ling Yang, Chun Yang, Ailin Luo

  Keywords: cognitive dysfunction, gut microbiota, Alzheimer’s disease, SAMP8, pseudo germ-free mice

  Published in Aging on June 10, 2018

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• Research PaperVolume 12, Issue 4pp 3175-3189

  Ligustilide improves aging-induced memory deficit by regulating mitochondrial related inflammation in SAMP8 mice

  Relevance score: 0.00

  Wen-Li Zhu, Jia-Yi Zheng, Wei-Wu Cai, Zhao Dai, Ben-Yue Li, Ting-Ting Xu, Hao-Fei Liu, Xiao-Qi Liu, Su-Fen Wei, Yi Luo, Hong Wang, Hua-Feng Pan, Qi Wang, Shi-Jie Zhang

  Keywords: Alzheimer’s disease, ligustilide, SAMP8 mice, mitochondrial dysfunction, neuroinflammation

  Published in Aging on February 16, 2020

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• Research PaperVolume 11, Issue 2pp 401-422

  3,4,5-Tricaffeoylquinic acid induces adult neurogenesis and improves deficit of learning and memory in aging model senescence-accelerated prone 8 mice

  Relevance score: 0.00

  Kazunori Sasaki, Julie Davies, Noelia Geribaldi Doldán, Sayo Arao, Farhana Ferdousi, Francis G. Szele, Hiroko Isoda

  Keywords: TCQA, SAMP8, spatial learning and memory, neurogenesis, BMP signaling

  Published in Aging on January 17, 2019

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• Research PaperVolume 13, Issue 23pp 25004-25024

  An efficient, non-invasive approach for in-vivo sampling of hair follicles: design and applications in monitoring DNA damage and aging

  Relevance score: 0.00

  Natalie Kudlova, Hanus Slavik, Pavlina Duskova, Tomas Furst, Josef Srovnal, Jiri Bartek, Martin Mistrik, Marian Hajduch

  Keywords: hair follicle cells, non-invasive sampling, irradiation, cellular senescence, DNA damage response

  Published in Aging on December 6, 2021

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• Research PaperVolume 13, Issue 3pp 3819-3842

  Four hub genes regulate tumor infiltration by immune cells, antitumor immunity in the tumor microenvironment, and survival outcomes in lung squamous cell carcinoma patients

  Relevance score: 0.00

  Tuo Zhang, Haitang Yang, Beibei Sun, Feng Yao

  Keywords: immunity, lung squamous carcinoma, single sample gene set enrichment analysis, robust rank aggregations, CIBERSORT

  Published in Aging on January 10, 2021

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• Research PaperVolume 16, Issue 8pp 7387-7404

  New insights from bidirectional Mendelian randomization: causal relationships between telomere length and mitochondrial DNA copy number in aging biomarkers

  Relevance score: 0.00

  Xinyu Yan, Peixuan Yang, Yani Li, Ting Liu, Yawen Zha, Ting Wang, Jingjing Zhang, Zhijun Feng, Minying Li

  Keywords: mitochondrial DNA copy number, causal relationship, telomere length, bidirectional two-sample Mendelian randomization

  Published in Aging on April 24, 2024

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• Research PaperVolume 16, Issue 1pp 701-713

  Platelet-derived growth factor subunit-B mediating the effect of dickkopf-1 on acute myocardial infarction risk: a two-step Mendelian randomization study

  Relevance score: 0.00

  Jun-Shan Li, Peng-Fei Zheng, Jing-Jing Rong, Zhao-Fen Zheng, Zheng-Yu Liu, Chang-Lu Wang

  Keywords: DKK1, acute myocardial infarction, PDGF-B, two-sample Mendelian randomization, mediation analysis

  Published in Aging on January 3, 2024

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• Research PaperVolume 15, Issue 18pp 9797-9808

  Investigating the causal effect of Dickkopf-1 on coronary artery disease and ischemic stroke: a Mendelian randomization study

  Relevance score: 0.00

  Peng-Fei Zheng, Jing-Jing Rong, Zhao-Fen Zheng, Zheng-Yu Liu, Hong-Wei Pan, Peng Liu

  Keywords: DKK1, CAD, IS, two-sample mendelian randomization

  Published in Aging on September 22, 2023

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• Research PaperVolume 15, Issue 11pp 4600-4624

  Impaired telomere pathway and fertility in Senescence-Accelerated Mice Prone 8 females with reproductive senescence

  Relevance score: 0.00

  Alba M. Polonio, Marta Medrano, Lucía Chico-Sordo, Isabel Córdova-Oriz, Mauro Cozzolino, José Montans, Sonia Herraiz, Emre Seli, Antonio Pellicer, Juan A. García-Velasco, Elisa Varela

  Keywords: telomere, telomerase, aging, fertility, ovary, SAMP8

  Published in Aging on May 23, 2023

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• EditorialVolume 15, Issue 7pp 2369-2370

  3-Deazaadenosine keeps senescence at bay

  Relevance score: 0.00

  Ana Guerrero, Jesús Gil

  Keywords: 3-deazaadenosine, senescence, aging, SAM

  Published in Aging on March 24, 2023

• Research PaperVolume 14, Issue 1pp 109-142

  Kampo formulas alleviate aging-related emotional disturbances and neuroinflammation in male senescence-accelerated mouse prone 8 mice

  Relevance score: 0.00

  Naoki Ito, Akiko Maruko, Kenshiro Oshima, Masaaki Yoshida, Kengo Honma, Chika Sugiyama, Takayuki Nagai, Yoshinori Kobayashi, Hiroshi Odaguchi, Norihiro Okada

  Keywords: aging, emotional disturbances, kososan, neuroinflammation, SAMP8 mice

  Published in Aging on January 3, 2022

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• Research PaperVolume 13, Issue 14pp 18131-18149

  Grape skin extract modulates neuronal stem cell proliferation and improves spatial learning in senescence-accelerated prone 8 mice

  Relevance score: 0.00

  Kazunori Sasaki, Noelia Geribaldi-Doldan, Francis G. Szele, Hiroko Isoda

  Keywords: grape skin, neuroprotection, neuronal stem cell, SAMP8, neuroinflammation

  Published in Aging on July 28, 2021

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• Research PaperVolume 11, Issue 18pp 7938-7947

  The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis

  Relevance score: 0.00

  Ebrahim Bani Hassan, Mostafa Alderghaffar, Fabien Wauquier, Veronique Coxam, Oddom Demontiero, Sara Vogrin, Yohann Wittrant, Gustavo Duque

  Keywords: aging, fish oil, marrow adipose tissue, osteoporosis, SAMP8 mouse

  Published in Aging on September 25, 2019

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• Research PaperVolume 7, Issue 11pp 937-955

  A comprehensive multiomics approach toward understanding the relationship between aging and dementia

  Relevance score: 0.00

  Antonio Currais, Joshua Goldberg, Catherine Farrokhi, Max Chang, Marguerite Prior, Richard Dargusch, Daniel Daugherty, Aaron Armando, Oswald Quehenberger, Pamela Maher, David Schubert

  Keywords: aging, Alzheimer's disease, multiomics, SAMP8 mice, inflammation, J147

  Published in Aging on November 11, 2015

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