Altmetric Top 100

Top Aging Publications Rated by Altmetric Attention Score

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Here Aging is releasing the list of its publications with the score higher than 100.

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Chemically induced reprogramming to reverse cellular aging

DNA methylation GrimAge strongly predicts lifespan and healthspan

DNA methylation-based measures of biological age: meta-analysis predicting time to death

Deep biomarkers of human aging: Application of deep neural networks to biomarker development

Reversal of cognitive decline: A novel therapeutic program

Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial

Examining sleep deficiency and disturbance and their risk for incident dementia and all-cause mortality in older adults across 5 years in the United States

Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults

Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1

Rapamycin for longevity: opinion article

Effects of exercise on cellular and tissue aging

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

An epigenetic biomarker of aging for lifespan and healthspan

Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series

Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age

Why does COVID-19 disproportionately affect older people?

The gut microbiome of healthy long-living people

Effect of paternal age on offspring birth defects: a systematic review and meta-analysis

Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice

Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial

Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2

Effects of transcutaneous vagus nerve stimulation in individuals aged 55 years or above: potential benefits of daily stimulation

Ketogenic diet in cancer therapy

Habitual tea drinking modulates brain efficiency: evidence from brain connectivity evaluation

Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990–2017: results from a global burden of disease study, 2017

Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin

Reversal of cognitive decline in Alzheimer's disease

Alcohol consumption and epigenetic age acceleration in young adults

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform

Fasting and cancer treatment in humans: A case series report

Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic

PCH-2 regulates Caenorhabditis elegans lifespan

COVID-19 mortality rate in children is U-shaped

New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

A review of the biomedical innovations for healthy longevity

Alcohol consumption and epigenetic age acceleration across human adulthood

Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine

Human mesenchymal stem cells treatment improved hepatic lesions and reversed gut microbiome disorder in non-alcoholic steatohepatitis

Iron: an underrated factor in aging

DNA methylation GrimAge version 2

Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging

Optimizing future well-being with artificial intelligence: self-organizing maps (SOMs) for the identification of islands of emotional stability

Shorter telomere lengths in patients with severe COVID-19 disease

Aged cells in human skeletal muscle after resistance exercise

PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging

Aging and brain plasticity

Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

Relationship between telomere shortening and early subjective depressive symptoms and cognitive complaints in older adults

Positive attitude towards life and emotional expression as personality phenotypes for centenarians

New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463

Antibiotics that target mitochondria extend lifespan in C. elegans

Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial

Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition

Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence

Aging and ischemic stroke

Optimism is not associated with two indicators of DNA methylation aging

Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer

Answering the ultimate question “What is the Proximal Cause of Aging?”

Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults

How can we modulate aging through nutrition and physical exercise? An epigenetic approach

Towards natural mimetics of metformin and rapamycin

Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test.

Are menopause, aging and prostate cancer diseases?

The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut

Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways

In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state

A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA)

In search of preventive strategies: novel high-CBD Cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues

Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects

Neurological involvement in the respiratory manifestations of COVID-19 patients

Effects of resveratrol on in vitro circadian clock gene expression in young and older human adipose-derived progenitor cells

DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife

From causes of aging to death from COVID-19

Old-age-induced obesity reversed by a methionine-deficient diet or oral administration of recombinant methioninase-producing Escherichia coli in C57BL/6 mice

Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy

Aging and aging-associated diseases: a microRNA-based endocrine regulation hypothesis

Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients

Spermidine delays aging in humans

Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation

Inhalational Alzheimer's disease: an unrecognized—and treatable—epidemic

Age- and sex-dependent changes in levels of circulating brain-enriched microRNAs during normal aging

Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence

Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?

Biomedical generative pre-trained based transformer language model for age-related disease target discovery

Rapamycin treatment early in life reprograms aging: hyperfunction theory and clinical practice.

White matter hyperintensity load is associated with premature brain aging

The cell rejuvenation atlas: leveraging network biology to identify master regulators of rejuvenation strategies

Deep biomarkers of aging and longevity: from research to applications

Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans

PsychoAge and SubjAge: development of deep markers of psychological and subjective age using artificial intelligence

Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis

p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model

Evidence of a pan-tissue decline in stemness during human aging

Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease

Targeted cancer therapy: the initial high concentration may slow down the selection for resistance

Growth and aging: a common molecular mechanism

Mapping of the gene network that regulates glycan clock of ageing