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Top Aging Publications Rated by Altmetric Attention Score

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Chemically induced reprogramming to reverse cellular aging
Chemically induced reprogramming to reverse cellular aging
DNA methylation GrimAge strongly predicts lifespan and healthspan
DNA methylation GrimAge strongly predicts lifespan and healthspan
DNA methylation-based measures of biological age: meta-analysis predicting time to death
DNA methylation-based measures of biological age: meta-analysis predicting time to death
Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression
Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression
Reversal of cognitive decline: A novel therapeutic program
Reversal of cognitive decline: A novel therapeutic program
Examining sleep deficiency and disturbance and their risk for incident dementia and all-cause mortality in older adults across 5 years in the United States
Examining sleep deficiency and disturbance and their risk for incident dementia and all-cause mortality in older adults across 5 years in the United States
Deep biomarkers of human aging: Application of deep neural networks to biomarker development
Deep biomarkers of human aging: Application of deep neural networks to biomarker development
Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial
Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial
Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series
Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series
Rapamycin for longevity: opinion article
Rapamycin for longevity: opinion article
Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults
Psychological factors substantially contribute to biological aging: evidence from the aging rate in Chinese older adults
Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1
Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1
Effects of exercise on cellular and tissue aging
Effects of exercise on cellular and tissue aging
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
An epigenetic biomarker of aging for lifespan and healthspan
An epigenetic biomarker of aging for lifespan and healthspan
Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial
Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial
Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age
Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age
Why does COVID-19 disproportionately affect older people?
Why does COVID-19 disproportionately affect older people?
The gut microbiome of healthy long-living people
The gut microbiome of healthy long-living people
Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice
Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice
Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus
Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus
Effect of paternal age on offspring birth defects: a systematic review and meta-analysis
Effect of paternal age on offspring birth defects: a systematic review and meta-analysis
Habitual tea drinking modulates brain efficiency: evidence from brain connectivity evaluation
Habitual tea drinking modulates brain efficiency: evidence from brain connectivity evaluation
Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2
Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2
Ketogenic diet in cancer therapy
Ketogenic diet in cancer therapy
Effects of transcutaneous vagus nerve stimulation in individuals aged 55 years or above: potential benefits of daily stimulation
Effects of transcutaneous vagus nerve stimulation in individuals aged 55 years or above: potential benefits of daily stimulation
Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system
Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system
Reversal of cognitive decline in Alzheimer's disease
Reversal of cognitive decline in Alzheimer's disease
Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study
Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study
Fasting and cancer treatment in humans: A case series report
Fasting and cancer treatment in humans: A case series report
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
Alcohol consumption and epigenetic age acceleration in young adults
Alcohol consumption and epigenetic age acceleration in young adults
Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990–2017: results from a global burden of disease study, 2017
Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990–2017: results from a global burden of disease study, 2017
Alcohol consumption and epigenetic age acceleration across human adulthood
Alcohol consumption and epigenetic age acceleration across human adulthood
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform
Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform
Brown adipose tissue enhances exercise performance and healthful longevity
Brown adipose tissue enhances exercise performance and healthful longevity
Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic
Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic
DNA methylation GrimAge version 2
DNA methylation GrimAge version 2
PCH-2 regulates Caenorhabditis elegans lifespan
PCH-2 regulates Caenorhabditis elegans lifespan
COVID-19 mortality rate in children is U-shaped
COVID-19 mortality rate in children is U-shaped
DNA methylation entropy is a biomarker for aging
DNA methylation entropy is a biomarker for aging
Iron: an underrated factor in aging
Iron: an underrated factor in aging
Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine
Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
A review of the biomedical innovations for healthy longevity
A review of the biomedical innovations for healthy longevity
Human mesenchymal stem cells treatment improved hepatic lesions and reversed gut microbiome disorder in non-alcoholic steatohepatitis
Human mesenchymal stem cells treatment improved hepatic lesions and reversed gut microbiome disorder in non-alcoholic steatohepatitis
Sex-specific longitudinal reversal of aging in old frail mice
Sex-specific longitudinal reversal of aging in old frail mice
SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells.
SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells.
Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging
Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging
Aging and brain plasticity
Aging and brain plasticity
Optimizing future well-being with artificial intelligence: self-organizing maps (SOMs) for the identification of islands of emotional stability
Optimizing future well-being with artificial intelligence: self-organizing maps (SOMs) for the identification of islands of emotional stability
Shorter telomere lengths in patients with severe COVID-19 disease
Shorter telomere lengths in patients with severe COVID-19 disease
Exercise as a geroprotector: focusing on epigenetic aging
Exercise as a geroprotector: focusing on epigenetic aging
Aged cells in human skeletal muscle after resistance exercise
Aged cells in human skeletal muscle after resistance exercise
PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging
PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants
Relationship between telomere shortening and early subjective depressive symptoms and cognitive complaints in older adults
Relationship between telomere shortening and early subjective depressive symptoms and cognitive complaints in older adults
Positive attitude towards life and emotional expression as personality phenotypes for centenarians
Positive attitude towards life and emotional expression as personality phenotypes for centenarians
New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
Aging and ischemic stroke
Aging and ischemic stroke
Antibiotics that target mitochondria extend lifespan in C. elegans
Antibiotics that target mitochondria extend lifespan in C. elegans
Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition
Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition
Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial
Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial
Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways
Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways
Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence
Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence
Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test.
Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test.
How can we modulate aging through nutrition and physical exercise? An epigenetic approach
How can we modulate aging through nutrition and physical exercise? An epigenetic approach
Optimism is not associated with two indicators of DNA methylation aging
Optimism is not associated with two indicators of DNA methylation aging
Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans
Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans
Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults
Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults
The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut
The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut
Answering the ultimate question “What is the Proximal Cause of Aging?”
Answering the ultimate question “What is the Proximal Cause of Aging?”
Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer
Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer
Towards natural mimetics of metformin and rapamycin
Towards natural mimetics of metformin and rapamycin
Are menopause, aging and prostate cancer diseases?
Are menopause, aging and prostate cancer diseases?
In search of preventive strategies: novel high-CBD Cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues
In search of preventive strategies: novel high-CBD Cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues
From causes of aging to death from COVID-19
From causes of aging to death from COVID-19
In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state
In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state
A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA)
A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA)
DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife
DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife
Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects
Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects
Effects of resveratrol on in vitro circadian clock gene expression in young and older human adipose-derived progenitor cells
Effects of resveratrol on in vitro circadian clock gene expression in young and older human adipose-derived progenitor cells
Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients
Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients
Neurological involvement in the respiratory manifestations of COVID-19 patients
Neurological involvement in the respiratory manifestations of COVID-19 patients
Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution
Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution
Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy
Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy
Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial
Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial
Aging and aging-associated diseases: a microRNA-based endocrine regulation hypothesis
Aging and aging-associated diseases: a microRNA-based endocrine regulation hypothesis
Meta-analysis of the association between nut consumption and the risks of cancer incidence and cancer-specific mortality
Meta-analysis of the association between nut consumption and the risks of cancer incidence and cancer-specific mortality
Old-age-induced obesity reversed by a methionine-deficient diet or oral administration of recombinant methioninase-producing Escherichia coli in C57BL/6 mice
Old-age-induced obesity reversed by a methionine-deficient diet or oral administration of recombinant methioninase-producing Escherichia coli in C57BL/6 mice
Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey
Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey
Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis
Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis
Work-related stress and well-being in association with epigenetic age acceleration: A Northern Finland Birth Cohort 1966 Study
Work-related stress and well-being in association with epigenetic age acceleration: A Northern Finland Birth Cohort 1966 Study
Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation
Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation
Inhalational Alzheimer's disease: an unrecognized—and treatable—epidemic
Inhalational Alzheimer's disease: an unrecognized—and treatable—epidemic
Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease
Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease
Biomedical generative pre-trained based transformer language model for age-related disease target discovery
Biomedical generative pre-trained based transformer language model for age-related disease target discovery
Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results
Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results
Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?
Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?