Special Collection on p53

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Altered S-nitrosylation of p53 is responsible for impaired antioxidant response in skeletal muscle during aging

Sara Baldelli, Maria Rosa Ciriolo

https://doi.org/10.18632/aging.101139pp 3450—3467

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Fortifying p53 – beyond Mdm2 inhibitors

Anusha Sriraman, Yizhu Li, Matthias Dobbelstein

https://doi.org/10.18632/aging.101073pp 1836—1837

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Targeting mutant p53 for cancer therapy

Moshe Oren, Perry Tal, Varda Rotter

https://doi.org/10.18632/aging.100992pp 1159—1160

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The p53/miR-17/Smurf1 pathway mediates skeletal deformities in an age-related model via inhibiting the function of mesenchymal stem cells

Wenjia Liu, Meng Qi, Anna Konermann, Liqiang Zhang, Fang Jin, Yan Jin

https://doi.org/10.18632/aging.100728pp 205—216

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Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

Elena A. Komarova, Marina P. Antoch, Liliya R. Novototskaya, Olga B. Chernova, Geraldine Paszkiewicz, Olga V. Leontieva, Mikhail V. Blagosklonny, Andrei V. Gudkov

https://doi.org/http://dx.doi.org/10.18632/aging.100498pp 709—714

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New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53^−/− mice by delaying carcinogenesis

Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski, Olga B. Chernova, Alexander Polinsky, Mikhail V. Blagosklonny, Andrei V. Gudkov, Marina P. Antoch

https://doi.org/http://dx.doi.org/10.18632/aging.100496pp 715—722

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Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?

Mikhail V. Blagosklonny

https://doi.org/http://dx.doi.org/10.18632/aging.100475pp 450—455

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cep-1/p53-dependent dysplastic pathology of the aging C. elegans gonad

Mathew D. McGee, Nicholas Day, Jill Graham, Simon Melov

https://doi.org/http://dx.doi.org/10.18632/aging.100448pp 256—269

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p53 governs telomere regulation feedback too, via TRF2

Izumi Horikawa, Kaori Fujita, Curtis C. Harris

https://doi.org/http://dx.doi.org/10.18632/aging.100271pp 26—32

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HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation

Lavinia Nardinocchi, Rosa Puca, Gabriella D'Orazi

https://doi.org/http://dx.doi.org/10.18632/aging.100254pp 33—43

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p53, ROS and senescence in the control of aging

Arnaud Vigneron, Karen H. Vousden

https://doi.org/http://dx.doi.org/10.18632/aging.100189pp 471—474

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P53 and aging: A fresh look at an old paradigm

Masha V. Poyurovsky, Carol Prives

https://doi.org/http://dx.doi.org/10.18632/aging.100179pp 380—382

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SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence

Frédérick A. Mallette, Viviane Calabrese, Subburaj Ilangumaran, Gerardo Ferbeyre

https://doi.org/http://dx.doi.org/10.18632/aging.100163pp 445—452

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The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

Lioubov G. Korotchkina, Olga V. Leontieva, Elena I. Bukreeva, Zoya N. Demidenko, Andrei V. Gudkov, Mikhail V. Blagosklonny

https://doi.org/http://dx.doi.org/10.18632/aging.100160pp 344—352

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Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy

Morris Waskar, Gary N. Landis, Jie Shen, Christina Curtis, Kevin Tozer, Diana Abdueva, Dmitriy Skvortsov, Simon Tavaré, John Tower

https://doi.org/10.18632/aging.100099pp 903—936

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The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence

Sebastian Haferkamp, Sieu L Tran, Therese M Becker, Lyndee L Scurr, Richard F Kefford, Helen Rizos

https://doi.org/http://dx.doi.org/10.18632/aging.100051pp 542—556

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Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

Katherine Heminger, Michael Markey, Meldrick Mpagi, Steven J. Berberich

https://doi.org/http://dx.doi.org/10.18632/aging.100008pp 89—108

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