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• Research PaperVolume 17, Issue 4pp 885-907

  Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK inhibition

  Relevance score: 0.00

  Mehdi Razazian, Sheyda Bahiraii, Azmat Sohail, Markus Mandl, Isratul Jannat, Georg Beilhack, Ioana Alesutan, Jakob Voelkl

  Keywords: vascular calcification, vascular smooth muscle cells, fisetin, dual-specificity phosphatase 1, p38 MAPK

  Published in Aging on April 2, 2025

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• Research PaperVolume 17, Issue 2pp 448-463

  Chronic β3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice

  Relevance score: 0.00

  Duraipandy Natarajan, Shoba Ekambaram, Stefano Tarantini, Raghavendra Y. Nagaraja, Andriy Yabluchanskiy, Andria F. Hedrick, Vibhudutta Awasthi, Madhan Subramanian, Anna Csiszar, Priya Balasubramanian

  Keywords: vascular cognitive impairment, endothelial function, glucose uptake, beta 3 adrenergic receptor agonist, blood-brain barrier leakage

  Published in Aging on February 19, 2025

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• Research PaperVolume 16, Issue 11pp 9369-9385

  Identification of key genes and biological pathways associated with vascular aging in diabetes based on bioinformatics and machine learning

  Relevance score: 0.00

  Sha Wang, Xia Wang, Jing Chen, Min Wang, Chi Zhang

  Keywords: diabetes, cardiovascular disease, vascular aging, vascular smooth muscle cell (VSMC), bioinformatics, machine learning

  Published in Aging on May 27, 2024

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• Research PaperVolume 16, Issue 6pp 5065-5076

  The protective effects of Irbesartan in cognitive impairment in hypertension

  Relevance score: 0.00

  Shengyun Hao, Qian He, Yuan Yuan, Qiong Mu

  Keywords: vascular cognitive impairment (VCI), Irbesartan, hypertension, cognitive impairment, cAMP/CREB

  Published in Aging on March 23, 2024

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• Research PaperVolume 16, Issue 5pp 4363-4377

  Probucol protects against brain damage caused by intra-neural pyroptosis in rats with vascular dementia through inhibition of the Syk/Ros pathway

  Relevance score: 0.00

  Jingyi Zhu, Jing Du, Wenhui Kou, Chenling Liu, Jianchun Fan, Ziyan Zhu, Lexiu Deng, Lingling Guan, Yuandi Wang, Aimei Yu

  Keywords: vascular dementia, pyroptosis, probucol, spleen tyrosine kinase, oxidative stress

  Published in Aging on February 23, 2024

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• Research PaperVolume 16, Issue 3pp 2438-2456

  Interaction of Sp1 and Setd8 promotes vascular smooth muscle cells apoptosis by activating Mark4 in vascular calcification

  Relevance score: 0.00

  Yun Li, Meijuan Cheng, Jingjing Jin, Dongxue Zhang, Shenglei Zhang, Yaling Bai, Jinsheng Xu

  Keywords: vascular calcification, apoptosis, Mark4, Sp1, Setd8

  Published in Aging on February 1, 2024

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• Research PaperVolume 15, Issue 21pp 12264-12274

  Influences and mechanism of erythropoietin on the cognitive function of vascular dementia rats

  Relevance score: 0.00

  Zhipeng Tang, Xiuqin Li, Nan Yin, Ming Zhao, Qingchuan Hu, Peiyuan Lv

  Keywords: vascular dementia, erythropoietin, oxidative stress, cell apoptosis

  Published in Aging on November 6, 2023

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• Research PaperVolume 15, Issue 1pp 70-91

  Histone methyltransferase Smyd2 drives vascular aging by its enhancer-dependent activity

  Relevance score: 0.00

  Zhenghua Su, Haibi Su, Jie Xu, Gang Wei, Lefeng Qu, Ting Ni, Di Yang, Yizhun Zhu

  Keywords: vascular aging, Smyd2, H3K4me1, enhancer-dependent activity

  Published in Aging on December 28, 2022

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• Research PaperVolume 15, Issue 4pp 982-1003

  Identification of cellular heterogeneity and key signaling pathways associated with vascular remodeling and calcification in young and old primate aortas based on single-cell analysis

  Relevance score: 0.00

  Yehu Yin, Congcong Huang, Zidi Wang, Pan Huang, Shanshan Qin

  Keywords: vascular aging, scRNA-seq, cellular heterogeneity, cell-cell communication, EGF

  Published in Aging on December 23, 2022

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• Research PaperVolume 14, Issue 9pp 3910-3920

  Vascular function in the aging human brain during muscle exertion

  Relevance score: 0.00

  Maijian Zhu, Tania Xu Yar Lee, Yu-Wen Hsieh, Li-Fan Lai, Giancarlo Condello, Cyril J. Donnelly, Marc Smith, Sareena Hanim Hamzah, Boon-Hooi Lim, Chih-Yang Huang, Nai-Fang Chi, Chia-Hua Kuo

  Keywords: frailty, vascular function, muscle strength, endothelial function, NIRS

  Published in Aging on May 2, 2022

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• Research PaperVolume 13, Issue 17pp 20935-20961

  Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients

  Relevance score: 0.00

  Ronit Shapira, Amos Gdalyahu, Irit Gottfried, Efrat Sasson, Amir Hadanny, Shai Efrati, Pablo Blinder, Uri Ashery

  Keywords: Alzheimer's disease, hyperbaric oxygen therapy, vascular dysfunction, cerebral blood flow, amyloid burden

  Published in Aging on September 9, 2021

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• Research PaperVolume 13, Issue 11pp 14651-14674

  Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

  Relevance score: 0.00

  Sang-Ha Baik, Sharmelee Selvaraji, David Y. Fann, Luting Poh, Dong-Gyu Jo, Deron R. Herr, Shenpeng R. Zhang, Hyun Ah Kim, Michael De Silva, Mitchell K.P. Lai, Christopher Li-Hsian Chen, Grant R. Drummond, Kah-Leong Lim, Christopher G. Sobey, Thiruma V. Arumugam

  Keywords: aging, vascular dementia, transcriptome, chronic cerebral hypoperfusion, brain

  Published in Aging on June 1, 2021

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• Research PaperVolume 13, Issue 10pp 14001-14014

  Adalimumab ameliorates memory impairments and neuroinflammation in chronic cerebral hypoperfusion rats

  Relevance score: 0.00

  Jing-Jing Xu, Si Guo, Rui Xue, Lin Xiao, Jun-Na Kou, Yu-Qiong Liu, Jun-Ya Han, Jing-Jie Fu, Na Wei

  Keywords: adalimumab, vascular dementia, neuroinflammation

  Published in Aging on May 24, 2021

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• Research PaperVolume 13, Issue 7pp 9542-9565

  Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca²⁺/CaMKII signal pathway

  Relevance score: 0.00

  Ting-Ting Chen, Xue Zhou, Yi-Ni Xu, Yue Li, Xiao-Ying Wu, Quan Xiang, Ling-Yun Fu, Xiao-Xia Hu, Ling Tao, Xiang-Chun Shen

  Keywords: gastrodin, vascular dementia, autophagic flux, Ca²⁺, CaMKII

  Published in Aging on March 10, 2021

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• Research PaperVolume 13, Issue 3pp 4409-4427

  Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress, inflammation, and remodeling

  Relevance score: 0.00

  Shushi Huang, Shengban You, Jinfu Qian, Chengyi Dai, Siyuan Shen, Jun Wang, Weijian Huang, Guang Liang, Gaojun Wu

  Keywords: vascular remodeling, MD2, inflammation, oxidative stress, VSMCs

  Published in Aging on January 20, 2021

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• Research PaperVolume 12, Issue 21pp 21220-21235

  Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure

  Relevance score: 0.00

  Fang He, Ling Li, Pei-Pei Li, Yan Deng, Yuan-Yuan Yang, Yi-Xuan Deng, Hong-Hong Luo, Xin-Tong Yao, Yu-Xi Su, Hua Gan, Bai-Cheng He

  Keywords: vascular calcification, TGF-β1, COX-2, sclerostin, chronic kidney disease

  Published in Aging on November 6, 2020

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• Research PaperVolume 12, Issue 21pp 21423-21445

  Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging

  Relevance score: 0.00

  Di Yang, Qing Wang, Gang Wei, Jiaxue Wu, Yi Chun Zhu, Qing Zhu, Ting Ni, Xinhua Liu, Yi Zhun Zhu

  Keywords: vascular endothelial cell, PARP16, angiotensin II, endoplasmic reticulum, Smyd3

  Published in Aging on November 3, 2020

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• Research PaperVolume 12, Issue 15pp 15603-15623

  Transcriptome analysis of mouse aortae reveals multiple novel pathways regulated by aging

  Relevance score: 0.00

  Ping Gao, Pan Gao, Mihyun Choi, Kavya Chegireddy, Orazio J. Slivano, Jinjing Zhao, Wei Zhang, Xiaochun Long

  Keywords: transcriptome, arterial aging, protein folding control, circadian clock, vascular smooth muscle differentiation

  Published in Aging on August 15, 2020

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• Research PaperVolume 12, Issue 15pp 15682-15704

  Vascular, inflammatory and metabolic risk factors in relation to dementia in Parkinson’s disease patients with type 2 diabetes mellitus

  Relevance score: 0.00

  Ting Wang, Feilan Yuan, Zhenze Chen, Shuzhen Zhu, Zihan Chang, Wanlin Yang, Bin Deng, Rongfang Que, Peihua Cao, Yinxia Chao, Lingling Chan, Ying Pan, Yanping Wang, Linting Xu, Qiurong Lyu, Piu Chan, Midori A. Yenari, Eng-King Tan, Qing Wang

  Keywords: vascular inflammation, risk factor, dementia, Parkinson's disease, type 2 diabetes mellitus

  Published in Aging on August 15, 2020

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• Research PaperVolume 12, Issue 16pp 16111-16125

  Testosterone ameliorates vascular aging via the Gas6/Axl signaling pathway

  Relevance score: 0.00

  Yan-Qing Chen, Hui-Min Zhou, Fang-Fang Chen, Ya-Peng Liu, Lu Han, Ming Song, Zhi-Hao Wang, Wei Zhang, Yuan-Yuan Shang, Ming Zhong

  Keywords: vascular aging, testosterone, Gas6, Axl, vascular stiffening

  Published in Aging on July 27, 2020

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