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• Research PaperVolume 8, Issue 11pp 2915-2926

  Discovery of piperlongumine as a potential novel lead for the development of senolytic agents

  Relevance score: 0.00

  Yingying Wang, Jianhui Chang, Xingui Liu, Xuan Zhang, Suping Zhang, Xin Zhang, Daohong Zhou, Guangrong Zheng

  Keywords: piperlongumine, aging, senescent cells, senolytic agents, ABT-263, reactive oxygen species, synergistic effect

  Published in Aging on November 19, 2016

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• ReviewVolume 16, Issue 12pp 10657-10665

  Senescent cell-derived vaccines: a new concept towards an immune response against cancer and aging?

  Relevance score: 0.00

  João Pessoa, Sandrina Nóbrega-Pereira, Bruno Bernardes de Jesus

  Keywords: cancer, immunotherapy, tumor-associated senescent cells, senescence, antigen, vaccine

  Published in Aging on June 26, 2024

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• CorrectionVolume 16, Issue 14pp 11475-11476

  Correction for: Iron retardation in lysosomes protects senescent cells from ferroptosis

  Relevance score: 0.00

  Yujing Feng, Huaiqing Wei, Meng Lyu, Zhiyuan Yu, Jia Chen, Xinxing Lyu, Fengfeng Zhuang

  Keywords: iron accumulation, senescent cells, lysosome, ferroptosis, ferritinophagy

  Published in Aging on July 31, 2024

• Research PaperVolume 16, Issue 9pp 7683-7703

  Iron retardation in lysosomes protects senescent cells from ferroptosis

  Relevance score: 0.00

  Yujing Feng, Huaiqing Wei, Meng Lyu, Zhiyuan Yu, Jia Chen, Xinxing Lyu, Fengfeng Zhuang

  Keywords: iron accumulation, senescent cells, lysosome, ferroptosis, ferritinophagy

  Published in Aging on April 26, 2024

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• Research PaperVolume 12, Issue 14pp 15050-15057

  Establishing a density-based method to separate proliferating and senescent cells from bone marrow stromal cells

  Relevance score: 0.00

  Fei Xu, Qiang Zhang, Haitao Wang

  Keywords: bone marrow stromal cells, cell transplantation, density-based method, proliferating cells, senescent cells

  Published in Aging on July 25, 2020

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• Research PaperVolume 17, Issue 11pp 2688-2716

  SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells

  Relevance score: 0.00

  Ryan Wallis, Bethany K. Hughes, Madeleine Moore, Emily A. O’Sullivan, Luke C. McIlvenna, Luke Gammon, Anthony Hope, Fiona Bellany, Parul Dixit, Claire Mackenzie, Charlotte Green, David Gray, Cleo L. Bishop

  Keywords: SAMP-Score, senescence, senescent marker positive cancer cells, Sen-Mark+, machine learning, pro-senescence, high-throughput compound screening

  Published in Aging on October 30, 2025

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• Research PerspectiveVolume 3, Issue 2pp 168-174

  Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker

  Relevance score: 0.00

  Christophe E. Redon, Asako J. Nakamura, Olga A. Martin, Palak R. Parekh, Urbain S. Weyemi, William M. Bonner

  Keywords: DNA damage, DNA repair, γ -H2AX, double-strand break, biomarker, cancer, senescent cells

  Published in Aging on February 11, 2011

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• Research Paper

  Senescent phenotype of astrocytes leads to microglia activation and neuronal death

  Relevance score: 0.00

  Wenyou Zhang, Xuehan Yang, Jingyue Liu, Yichen Pan, Ming Zhang, Li Chen

  Keywords: aging, microglia activation, senescent phenotype of astrocytes, cell-to-cell interaction, neurons

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• Priority Research PaperVolume 13, Issue 12pp 15750-15769

  Acid ceramidase promotes senescent cell survival

  Relevance score: 0.00

  Rachel Munk, Carlos Anerillas, Martina Rossi, Dimitrios Tsitsipatis, Jennifer L. Martindale, Allison B. Herman, Jen-Hao Yang, Jackson A. Roberts, Vijay R. Varma, Poonam R. Pandey, Madhav Thambisetty, Myriam Gorospe, Kotb Abdelmohsen

  Keywords: senotherapy, post-transcriptional, SASP, senescent cell metabolism, translational control

  Published in Aging on June 8, 2021

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• Research PaperVolume 14, Issue 22pp 8914-8926

  Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model

  Relevance score: 0.00

  Kento Takaya, Tatsuyuki Ishii, Toru Asou, Kazuo Kishi

  Keywords: glutaminase inhibitor, human skin, senescent cell, aging, therapeutic agent

  Published in Aging on November 21, 2022

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• Research PaperVolume 14, Issue 13pp 5366-5375

  High TRB3 expression induces chondrocyte autophagy and senescence in osteoarthritis cartilage

  Relevance score: 0.00

  Yanqing Gu, Ren Yan, Yang Wang, Yiwen Zeng, Qingqiang Yao

  Keywords: TRB3, autophagy, senescent cell, osteoarthritis

  Published in Aging on July 1, 2022

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• Research PaperVolume 9, Issue 8pp 1867-1884

  p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

  Relevance score: 0.00

  Brandon M. Hall, Vitaly Balan, Anatoli S. Gleiberman, Evguenia Strom, Peter Krasnov, Lauren P. Virtuoso, Elena Rydkina, Slavoljub Vujcic, Karina Balan, Ilya I. Gitlin, Katerina I. Leonova, Camila R. Consiglio, Sandra O. Gollnick, Olga B. Chernova, Andrei V. Gudkov

  Keywords: aging, macrophage, senescent cell, p16(Ink4a), beta-galactosidase

  Published in Aging on August 2, 2017

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• Research PaperVolume 9, Issue 1pp 114-132

  Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis

  Relevance score: 0.00

  Massimiliano Mellone, Christopher J. Hanley, Steve Thirdborough, Toby Mellows, Edwin Garcia, Jeongmin Woo, Joanne Tod, Steve Frampton, Veronika Jenei, Karwan A. Moutasim, Tasnuva D. Kabir, Peter A Brennan, Giulia Venturi, Kirsty Ford, Nicolas Herranz, Kue Peng Lim, James Clarke, Daniel W. Lambert, Stephen S. Prime, Timothy J. Underwood, Pandurangan Vijayanand, Kevin W. Eliceiri, Christopher Woelk, Emma V. King, Jesus Gil, Christian H. Ottensmeier, Gareth J. Thomas

  Keywords: tumor microenvironment, myofibroblasts, senescence, collagen, extracellular matrix, senescent fibroblasts

  Published in Aging on December 15, 2016

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• Research PerspectiveVolume 3, Issue 5pp 555-563

  Embryonic anti-aging niche

  Relevance score: 0.00

  Irina M. Conboy, Hanadie Yousef, Michael J. Conboy

  Keywords: stem cell aging, regeneration, niche, senescent, cell cycle, Notch, TGF-β, MAPK, muscle, hESC

  Published in Aging on May 31, 2011

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