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• Research PaperVolume 11, Issue 2pp 573-589

  Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro

  Relevance score: 0.00

  Zhirui Fan, Lifeng Li, Xiaoli Li, Meng Zhang, Mengmeng Dou, Jing Zhao, Jing Cao, Xiaoming Deng, Mingzhi Zhang, Huixiang Li, Zhenhe Suo

  Keywords: anti-senescence, fumarate hydratase, rat lung fibroblasts

  Published in Aging on January 21, 2019

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• Research PaperVolume 14, Issue 9pp 3728-3756

  Single-cell transcriptomics reveals age-resistant maintenance of cell identities, stem cell compartments and differentiation trajectories in long-lived naked mole-rats skin

  Relevance score: 0.00

  Aleksandra Savina, Thierry Jaffredo, Frederic Saldmann, Chris G. Faulkes, Philippe Moguelet, Christine Leroy, Delphine Del Marmol, Patrice Codogno, Lucy Foucher, Antoine Zalc, Mélanie Viltard, Gérard Friedlander, Selim Aractingi, Romain H. Fontaine

  Keywords: naked mole-rat, skin, stem cells, wound healing, aging

  Published in Aging on May 4, 2022

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• Research PaperVolume 13, Issue 3pp 3239-3253

  Uncovering molecular mechanisms of regulated cell death in the naked mole rat

  Relevance score: 0.00

  Alexei Evdokimov, Alexei Popov, Elena Ryabchikova, Olga Koval, Svetlana Romanenko, Vladimir Trifonov, Irina Petruseva, Inna Lavrik, Olga Lavrik

  Keywords: regulated cell death, naked mole rat, apoptosis, necrosis, DNA damage

  Published in Aging on January 28, 2021

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• Research PaperVolume 12, Issue 21pp 22266-22290

  Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro

  Relevance score: 0.00

  Daniel Frankel, Matthew Davies, Bharat Bhushan, Yavuz Kulaberoglu, Paulina Urriola-Munoz, Justine Bertrand-Michel, Melissa R. Pergande, Andrew A. Smith, Swapan Preet, Thomas J. Park, Michele Vendruscolo, Kenneth S. Rankin, Stephanie M. Cologna, Janet R. Kumita, Nicolas Cenac, Ewan St John Smith

  Keywords: naked mole-rat, neurodegeneration, amyloid beta, brain, lipidomics

  Published in Aging on November 4, 2020

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• Research PaperVolume 12, Issue 5pp 4394-4406

  DNA methylation clocks as a predictor for ageing and age estimation in naked mole-rats, Heterocephalus glaber

  Relevance score: 0.00

  Robert Lowe, Amy F. Danson, Vardhman K. Rakyan, Selin Yildizoglu, Frédéric Saldmann, Melanie Viltard, Gérard Friedlander, Chris G. Faulkes

  Keywords: naked mole-rat, Heterocephalus glaber, methylation clocks, epigenetic clocks, ageing

  Published in Aging on March 3, 2020

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• Research PaperVolume 8, Issue 12pp 3468-3485

  Naked mole-rats maintain healthy skeletal muscle and Complex IV mitochondrial enzyme function into old age

  Relevance score: 0.00

  Elizabeth A Stoll, Nevena Karapavlovic, Hannah Rosa, Michael Woodmass, Karolina Rygiel, Kathryn White, Douglass M Turnbull, Chris G Faulkes

  Keywords: naked mole-rat, mitochondria, oxidative stress, animal models of aging, sarcopenia

  Published in Aging on December 19, 2016

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• Research PaperVolume 17, Issue 10pp 2598-2636

  Brain region-specific and systemic transcriptomic alterations in a human alpha-synuclein overexpressing rat model

  Relevance score: 0.00

  Vivien Hoof, Nicolas Casadei, Olaf Riess, Julia Schulze-Hentrich, Thomas Hentrich

  Keywords: alpha-synuclein, transgenic rat model, different brain regions, aging, transcriptome analysis

  Published in Aging on October 20, 2025

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• Research PaperVolume 13, Issue 22pp 24815-24828

  Atorvastatin combined with dexamethasone promote hematoma absorption in an optimized rat model of chronic subdural hematoma

  Relevance score: 0.00

  Dong Wang, Yueshan Fan, Jun Ma, Chuang Gao, Xuanhui Liu, Zilong Zhao, Huijie Wei, Guili Yang, Jinhao Huang, Rongcai Jiang, Jianning Zhang

  Keywords: atorvastatin combined with low-dose dexamethasone treatment, CSDH, optimized CSDH rat model, inflammatory activities, angiogenic processes

  Published in Aging on November 23, 2021

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• Research PaperVolume 13, Issue 3pp 3699-3711

  Dexrazoxane ameliorates radiation-induced heart disease in a rat model

  Relevance score: 0.00

  Long Li, Xiaoqi Nie, Peng Zhang, Yongbiao Huang, Li Ma, Fang Li, Minxiao Yi, Wan Qin, Xianglin Yuan

  Keywords: radiation-induced heart disease, dexrazoxane, apoptosis, reactive oxygen species, rat model

  Published in Aging on January 2, 2021

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• Research PaperVolume 12, Issue 9pp 8434-8458

  Genetic regulatory subnetworks and key regulating genes in rat hippocampus perturbed by prenatal malnutrition: implications for major brain disorders

  Relevance score: 0.00

  Jiaying Chen, Xinzhi Zhao, Li Cui, Guang He, Xinhui Wang, Fudi Wang, Shiwei Duan, Lin He, Qiang Li, Xiaodan Yu, Fuquan Zhang, Mingqing Xu

  Keywords: prenatal, famine, malnutrition, rat, transcriptome

  Published in Aging on May 11, 2020

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• Research PaperVolume 17, Issue 2pp 524-549

  Age, sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model

  Relevance score: 0.00

  Hoang Van M. Nguyen, Eleana Cabello, David Dyer, Chloe Fender, Manuel Garcia-Jaramillo, Norman G. Hord, Steven Austad, Arlan Richardson, Archana Unnikrishnan

  Keywords: gut microbiome, aging, mitochondria, rat, metabolomics

  Published in Aging on February 27, 2025

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• Research PaperVolume 15, Issue 4pp 1143-1157

  Allopregnanolone-mediated GABAA-Rα4 function in amygdala and hippocampus of PMDD liver qi-invasion syndrome model rats

  Relevance score: 0.00

  Ya Sun, Mingzhou Gao, Dongmei Gao, Dan Chen, Jieqiong Wang

  Keywords: ALLO, GABAA-Rα4, PMDD-LIS rat model, PROG, finasteride

  Published in Aging on February 23, 2023

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• Research PaperVolume 15, Issue 1pp 276-286

  Effects of NBP on postoperative cognitive dysfunction in rats via Nrf 2/ARE pathway

  Relevance score: 0.00

  Jianshuai He, Junqiong Gao, He Zhu, Yang Zhao, Xiaotian Zhang, Xiufang Wang, Shengnan Wan, Hongying Cao, Lin Zhai, Yuanyong Wang, Shilei Wang

  Keywords: NBP, POCD, Nrf 2/ARE pathway, anesthesiology, rat

  Published in Aging on January 9, 2023

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• Research PaperVolume 13, Issue 22pp 24524-24541

  Progressive reorganization of mitochondrial apparatus in aging skeletal muscle of naked mole rats (Heterocephalus glaber) as revealed by electron microscopy: potential role in continual maintenance of muscle activity

  Relevance score: 0.00

  Valeriya Vays, Irina Vangely, Chupalav Eldarov, Susanne Holtze, Thomas Hildebrandt, Lora Bakeeva, Vladimir Skulachev

  Keywords: aging, neoteny, mitochondria, naked mole-rat, electron microscopy

  Published in Aging on November 28, 2021

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• Research PaperVolume 13, Issue 11pp 15032-15043

  hAECs and their exosomes improve cardiac function after acute myocardial infarction in rats

  Relevance score: 0.00

  Yi-Qing Zhang, Lu Hong, Yu-Feng Jiang, Sheng-Da Hu, Nan-Nan Zhang, Lang-Biao Xu, Hong-Xia Li, Gui-Dong Xu, Ya-Feng Zhou, Kang-Yun Sun

  Keywords: human amniotic epithelial cells, exosome, acute myocardial infarction, rat

  Published in Aging on May 24, 2021

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• Research PaperVolume 12, Issue 17pp 17235-17256

  Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats

  Relevance score: 0.00

  Yeru Chen, Piao Zhang, Xianyi Lin, Huan Zhang, Jiamin Miao, Youfa Zhou, Gang Chen

  Keywords: sevoflurane, postoperative cognitive dysfunction, mitophagy, aged rat, rapamycin

  Published in Aging on September 9, 2020

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• Research PaperVolume 12, Issue 4pp 3218-3237

  LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes

  Relevance score: 0.00

  Guohua Lü, Lei Li, Bing Wang, Lei Kuang

  Keywords: osteoarthritis (OA), extracellular matrix (ECM), lncRNA LINC00623, miR-101, harvey rat sarcoma viral oncogene homolog (HRAS)

  Published in Aging on February 12, 2020

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• Research PaperVolume 9, Issue 2pp 573-582

  Adaptive sequence convergence of the tumor suppressor ADAMTS9 between small-bodied mammals displaying exceptional longevity

  Relevance score: 0.00

  Matthew J. Lambert, Christine V. Portfors

  Keywords: ADAMTS9, convergent evolution, longevity, naked mole-rat, microbats

  Published in Aging on February 26, 2017

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• Research PaperVolume 7, Issue 12pp 1171-1182

  DNA repair in species with extreme lifespan differences

  Relevance score: 0.00

  Sheila L MacRae, Matthew McKnight Croken, R.B Calder, Alexander Aliper, Brandon Milholland, Ryan R White, Alexander Zhavoronkov, Vadim N Gladyshev, Andrei Seluanov, Vera Gorbunova, Zhengdong D Zhang, Jan Vijg

  Keywords: genome maintenance, aging, longevity, RNA-seq, transcriptome, naked mole rat, DNA repair

  Published in Aging on December 30, 2015

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• ReviewVolume 6, Issue 11pp 913-920

  Questioning the preclinical paradigm: natural, extreme biology as an alternative discovery platform

  Relevance score: 0.00

  Rochelle Buffenstein, O. Lynne Nelson, Kevin C. Corbit

  Keywords: preclinical models, extremophiles, grizzly bear, insulin sensitivity, obesity, cardiac function, naked mole-rat, aging, cancer resistance

  Published in Aging on December 4, 2014

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