Search

Search Results

243 results found. Results per page: [ 20 ] [ 40 ] [ 60 ] [ 80 ] [ 100 ] [ 200 ] [ 300 ]

Sort by: [ Publication Date ] [ Score ]

Direction: [ Desc ] [ Asc ]

Year of publication: [ 2026 ] [ 2025 ] [ 2024 ] [ 2023 ] [ 2022 ] [ 2021 ] [ 2020 ] [ 2019 ] [ 2018 ] [ 2017 ] [ 2016 ] [ 2015 ] [ 2014 ] [ 2013 ] [ 2012 ] [ 2011 ] [ 2010 ] [ 2009 ] [ Any ]

Page: 12345678910111213 of 13

• Research PaperVolume 7, Issue 1pp 26-37

  Signaling pathway activation drift during aging: Hutchinson-Gilford Progeria Syndrome fibroblasts are comparable to normal middle-age and old-age cells

  Relevance score: 0.00

  Alexander M. Aliper, Antonei Benjamin Csoka, Anton Buzdin, Tomasz Jetka, Sergey Roumiantsev, Alexey Moskalev, Alex Zhavoronkov

  Keywords: Progeria, HGPS, Lamin, LMNA, aging, aging pathway, pathway activation, pathway drift, geroscope, geroprotectors, senescence

  Published in Aging on January 9, 2015

  Show abstract
• Research PaperVolume 6, Issue 12pp 1064-1075

  Pathway activation profiling reveals new insights into Age-related Macular Degeneration and provides avenues for therapeutic interventions

  Relevance score: 0.00

  Evgeny Makarev, Charles Cantor, Alex Zhavoronkov, Anton Buzdin, Alexander Aliper, Antonei Benjamin Csoka

  Keywords: AMD, Age-related Macular Degeneration, gene expression, Transcriptome profiling, signaling pathway activation strength

  Published in Aging on December 22, 2014

  Show abstract
• Research PaperVolume 14, Issue 1pp 286-296

  Yes-associated protein reacts differently in vascular smooth muscle cells under different intensities of mechanical stretch

  Relevance score: 0.00

  Xinhao Wang, Xiangdang Liang, Lujun Zhou, Shen Liu, Zhuoqun Fang, Chuanzhong Hu, Yigong Hou, Zhanshe Guo

  Keywords: Hippo pathway, YAP, mechanical stretch, proliferation, apoptosis

  Published in Aging on January 4, 2022

  Show abstract
• Research PaperVolume 6, Issue 3pp 207-214

  Hexosamine pathway but not interstitial changes mediates glucotoxicity in pancreatic β-cells as assessed by cytosolic Ca²⁺ response to glucose

  Relevance score: 0.00

  Kazuhiro Yanagida, Yuko Maejima, Putra Santoso, Zesemdorj Otgon-Uul, Yifei Yang, Kazuya Sakuma, Kenju Shimomura, Toshihiko Yada

  Keywords: Glucotoxicity, hexosamine pathway, insulin secretion

  Published in Aging on March 29, 2014

  Show abstract
• Research PaperVolume 4, Issue 10pp 715-722

  New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53^−/− mice by delaying carcinogenesis

  Relevance score: 0.00

  Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski, Olga B. Chernova, Alexander Polinsky, Mikhail V. Blagosklonny, Andrei V. Gudkov, Marina P. Antoch

  Keywords: mTOR pathway, p53−/−, lifespan, rapamycin, oral formulation, cancer prevention

  Published in Aging on October 29, 2012

  Show abstract
• Research Paper

  Chronic stress promotes premature ovarian failure in mice by inhibiting ovarian granulosa cell autophagy through PI3K-AKTmTOR pathway

  Relevance score: 0.00

  Zhibin Zhao, Xuefei Yuan, Baohua Zhao, Kai He

  Keywords: PI3K-AKT-mTOR pathway, premature ovarian failure (POF), ovarian granulosa cells (OGCs), chronic stress

  Published in Aging on October 8, 2024

  Show abstract
• Research PaperVolume 16, Issue 2pp 1516-1535

  Molecular map of cGAS-STING pathway-related genes in bladder cancer: the perspective toward immune microenvironment and prognosis

  Relevance score: 0.00

  Dong Wei, Ying Liu, Ying Yuan, Yishuai Li, Fangchao Zhao, Xuebo Qin

  Keywords: cGAS-STING pathway, bladder cancer, tumor immune, immune microenvironment, immune checkpoint inhibitors

  Published in Aging on January 17, 2024

  Show abstract
• Research PaperVolume 15, Issue 12pp 5426-5444

  Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway

  Relevance score: 0.00

  Lin Li, Hangyu Jiang, Yuqi Li, Xiaochong Xiang, Yueming Chu, Jie Tang, Kang Liu, Danqun Huo, Xiaofen Zhang

  Keywords: esophageal squamous cell carcinoma, chaetocin, ROS, Hippo pathway, apoptosis

  Published in Aging on June 14, 2023

  Show abstract
• Research PaperVolume 15, Issue 4pp 1210-1227

  Inhibition of apoptosis through AKT-mTOR pathway in ovarian cancer and renal cancer

  Relevance score: 0.00

  Hongrun Chen, Lianfeng Zhang, Meini Zuo, Xiaowen Lou, Bin Liu, Taozhu Fu

  Keywords: Akt-mTOR pathway, renal cancer, ovarian cancer, bioinformatics, verification, biomarker

  Published in Aging on February 27, 2023

  Show abstract
• Research PaperVolume 15, Issue 9pp 3381-3393

  PI3K-Akt signaling pathway based on network pharmacology for the anti-Alzheimer’s disease effect of licorice stem flavonoids

  Relevance score: 0.00

  Hongyan Pei, Lei He, Meiling Shi, Xiangjuan Guo, Weijia Chen, Jianming Li, Zhongmei He, Rui Du

  Keywords: network pharmacology, Alzheimer’s disease, licorice stem flavonoids, PI3K-Akt signalling pathway

  Published in Aging on February 22, 2023

  Show abstract
• Research PaperVolume 14, Issue 12pp 5250-5270

  TRPM7 via calcineurin/NFAT pathway mediates metastasis and chemotherapeutic resistance in head and neck squamous cell carcinoma

  Relevance score: 0.00

  Tsung-Ming Chen, Chih-Ming Huang, Ming-Shou Hsieh, Chun-Shu Lin, Wei-Hwa Lee, Chi-Tai Yeh, Shao-Cheng Liu

  Keywords: HNSCC, transient receptor potential cation channel subfamily M member 7, chemoresistance, calcineurin/NFAT pathway, cancer stem cell

  Published in Aging on June 29, 2022

  Show abstract
• Research PaperVolume 13, Issue 1pp 1096-1119

  The endothelial nitric oxide synthase/cyclic guanosine monophosphate/protein kinase G pathway activates primordial follicles

  Relevance score: 0.00

  Peikun Zhao, Zidai Song, Yan Wang, Han Cai, Xiaoyan Du, Changlong Li, Jianyi Lv, Xin Liu, Meng Guo, Zhenwen Chen

  Keywords: eNOS/cGMP/PKG pathway, mTOR, FBXW7, primordial follicle activation, ubiquitination

  Published in Aging on December 3, 2020

  Show abstract
• Research PaperVolume 12, Issue 10pp 9311-9327

  Single nucleotide polymorphisms within the Wnt pathway predict the risk of bone metastasis in patients with non-small cell lung cancer

  Relevance score: 0.00

  Yiquan Xu, Hongru Li, Lihong Weng, Yanqin Qiu, Junqiong Zheng, Huaqiang He, Dongmei Zheng, Junfan Pan, Fan Wu, Yusheng Chen

  Keywords: Wnt signaling pathway, polymorphisms, bone metastasis, risk, biomarker

  Published in Aging on May 26, 2020

  Show abstract
• Research PaperVolume 12, Issue 3pp 2246-2260

  The protein tyrosine kinase inhibitor, Genistein, delays intervertebral disc degeneration in rats by inhibiting the p38 pathway-mediated inflammatory response

  Relevance score: 0.00

  Jun Ge, Quan Zhou, Xiaoqiang Cheng, Jiale Qian, Qi Yan, Cenhao Wu, Yufeng Chen, Huilin Yang, Jun Zou

  Keywords: p38 MAPK pathway, intervertebral disc degeneration, Genistein, phosphorylation

  Published in Aging on February 5, 2020

  Show abstract
• Research PaperVolume 10, Issue 11pp 3161-3172

  AMPKα pathway involved in hepatic triglyceride metabolism disorder in diet-induced obesity mice following Escherichia coli Infection

  Relevance score: 0.00

  Jing Fang, Fengyuan Wang, Hetao Song, Zhengyi Wang, Zhicai Zuo, Hengmin Cui, Yiping Jia, Junliang Deng, Shumin Yu, Yanchun Hu, Liuhong Shen, Xiaoping Ma, Zhihua Ren, Liping Gou

  Keywords: Escherichia coli infection, hepatic triglyceride metabolism, AMPKα pathway, mouse

  Published in Aging on November 6, 2018

  Show abstract
• Research PaperVolume 6, Issue 8pp 675-689

  Metabolic clock generates nutrient anticipation rhythms in mTOR signaling

  Relevance score: 0.00

  Rohini V. Khapre, Sonal A. Patel, Anna A. Kondratova, Amol Chaudhary, Nikkhil Velingkaar, Marina P. Antoch, Roman V. Kondratov

  Keywords: Food anticipation, metabolism, mTOR signaling pathway, biological clocks, circadian clocks

  Published in Aging on August 26, 2014

  Show abstract
• Research PaperVolume 16, Issue 18pp 12498-12509

  SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma

  Relevance score: 0.00

  Guojing Chai, Yingbo Nan, Haili Zhao, Qingchuan Hu

  Keywords: lung adenocarcinoma, SHP2, TAM, STAT3/STAT6 signaling pathway

  Published in Aging on May 14, 2024

  Show abstract
• Research PaperVolume 16, Issue 2pp 1845-1859

  Activation of Notch-1 signaling pathway in macrophages to secrete PD-L1 and regulate cytotoxicity of CAR-T cells in diffuse large B-cell lymphoma

  Relevance score: 0.00

  Weijing Li, Lili Wu, Chen Huang, Hongqing Ma, Lianjing Wang, Wei Liu, Lihong Liu

  Keywords: diffuse large B-cell lymphoma, macrophages, Notch-1/IRE1/XBP1s signaling pathway, PD-L1, CAR-T cells

  Published in Aging on January 22, 2024

  Show abstract
• Research PaperVolume 15, Issue 20pp 11471-11488

  The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study

  Relevance score: 0.00

  Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu

  Keywords: osteoporosis, Wnt signaling pathway, TERT, H₂O₂, bilateral ovariectomy

  Published in Aging on October 19, 2023

  Show abstract
• Research PaperVolume 15, Issue 20pp 11162-11183

  Machine learning developed a PI3K/Akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer

  Relevance score: 0.00

  Xiaofang Han, Liu Yang, Hui Tian, Yuanyuan Ji

  Keywords: immunotherapy, prognostic signature, ovarian cancer, machine learning, PI3K/Akt pathway

  Published in Aging on October 17, 2023

  Show abstract