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Page: 12 of 2

• Research PaperVolume 15, Issue 24pp 15228-15242

  Causal effects of lipid-lowering therapies on aging-related outcomes and risk of cancers: a drug-target Mendelian randomization study

  Relevance score: 0.00

  Han Chen, Xinyu Tang, Wei Su, Shuo Li, Ruoyun Yang, Hong Cheng, Guoxin Zhang, Xiaoying Zhou

  Keywords: lipid-lowering drugs, aging, Mendelian randomization

  Published in Aging on December 19, 2023

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• Research PaperVolume 11, Issue 24pp 12428-12451

  System level characterization of small molecule drugs and their affected long noncoding RNAs

  Relevance score: 0.00

  Haixiu Yang, Yanan Jiang, Yunpeng Zhang, Yanjun Xu, Chunlong Zhang, Junwei Han, Fei Su, Xiaoqi Liu, Kai Mi, Bing Liu, Desi Shang

  Keywords: small molecule drugs, long noncoding RNAs, network, pharmacological analysis, tissue-specificity

  Published in Aging on December 18, 2019

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• ReviewVolume 1, Issue 3pp 281-288

  Validation of anti-aging drugs by treating age-related diseases

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: anti-aging drugs, diseases, cancer, atherosclerosis, resveratrol, rapamycin, metformin

  Published in Aging on March 28, 2009

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• Research PaperVolume 14, Issue 23pp 9466-9483

  Identification of natural products and FDA-approved drugs for targeting cancer stem cell (CSC) propagation

  Relevance score: 0.00

  Gloria Bonuccelli, Federica Sotgia, Michael P. Lisanti

  Keywords: cancer stem cells, drug screening, natural compounds, FDA approved drugs, mammospheres

  Published in Aging on December 1, 2022

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• Research PaperVolume 10, Issue 11pp 3294-3307

  Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

  Relevance score: 0.00

  Bela Ozsvari, John R. Nuttall, Federica Sotgia, Michael P. Lisanti

  Keywords: drug repurposing, aging, senescence, senolytic drugs, antibiotics, azithromycin, roxithromycin

  Published in Aging on November 14, 2018

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• Research PaperVolume 15, Issue 17pp 9193-9216

  Identification of a novel competing endogenous RNA network and candidate drugs associated with ferroptosis in aldosterone-producing adenomas

  Relevance score: 0.00

  Yu Hanxiao, Yang Boyun, Jia Minyue, Song Xiaoxiao

  Keywords: aldosterone-producing adenomas, ferroptosis, competing endogenous RNA, candidate drugs, differentially expressed genes

  Published in Aging on September 13, 2023

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• Research PaperVolume 15, Issue 13pp 6073-6099

  Predicting lifespan-extending chemical compounds for C. elegans with machine learning and biologically interpretable features

  Relevance score: 0.00

  Caio Ribeiro, Christopher K. Farmer, João Pedro de Magalhães, Alex A. Freitas

  Keywords: lifespan-extension compounds, longevity drugs, machine learning, feature selection

  Published in Aging on July 13, 2023

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• Research PaperVolume 13, Issue 10pp 14234-14257

  Integrated bioinformatic analysis reveals the underlying molecular mechanism of and potential drugs for pulmonary arterial hypertension

  Relevance score: 0.00

  Haoru Dong, Xiuchun Li, Mengsi Cai, Chi Zhang, Weiqi Mao, Ying Wang, Qian Xu, Mayun Chen, Liangxing Wang, Xiaoying Huang

  Keywords: PAH, DEGs, hub gene, molecular docking, potential drugs, bioinformatics

  Published in Aging on May 18, 2021

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• EditorialVolume 9, Issue 9pp 1951-1952

  Targeting neuroinflammation - a potential for anti-aging interventions

  Relevance score: 0.00

  Gillian Cady, Marianna Sadagurski

  Keywords: hypothalamic inflammation, anti-aging drugs, sex differences, longevity

  Published in Aging on September 22, 2017

• Research PaperVolume 9, Issue 7pp 1721-1737

  Machine learning for predicting lifespan-extending chemical compounds

  Relevance score: 0.00

  Diogo G. Barardo, Danielle Newby, Daniel Thornton, Taravat Ghafourian, João Pedro de Magalhães, Alex A. Freitas

  Keywords: longevity, anti-ageing drugs, pharmaceutical interventions, ageing, bioinformatics, C. elegans, machine learning

  Published in Aging on July 18, 2017

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• Research PaperVolume 13, Issue 14pp 18701-18717

  Development and validation of a novel epigenetic-related prognostic signature and candidate drugs for patients with lung adenocarcinoma

  Relevance score: 0.00

  Zhihao Wang, Kidane Siele Embaye, Qing Yang, Lingzhi Qin, Chao Zhang, Liwei Liu, Xiaoqian Zhan, Fengdi Zhang, Xi Wang, Shenghui Qin

  Keywords: lung adenocarcinoma, epigenetic-related genes, drugs, prognostic, TCGA

  Published in Aging on July 20, 2021

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• Research PaperVolume 14, Issue 8pp 3365-3386

  Wild type and gain of function mutant TP53 can regulate the sensitivity of pancreatic cancer cells to chemotherapeutic drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 pathway inhibitors, nutraceuticals and alter metabolic properties

  Relevance score: 0.00

  James A. McCubrey, Akshaya K. Meher, Shaw M. Akula, Stephen L. Abrams, Linda S. Steelman, Michelle M. LaHair, Richard A. Franklin, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Fulvio Barbaro, Przemysław Duda, Agnieszka Gizak

  Keywords: TP53, targeted therapy, PDAC, chemotherapeutic drugs, metabolic properties

  Published in Aging on April 27, 2022

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• Research PaperVolume 13, Issue 12pp 15833-15874

  The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence

  Relevance score: 0.00

  Dominika Bloniarz, Jagoda Adamczyk-Grochala, Anna Lewinska, Maciej Wnuk

  Keywords: DNMT2/TRDMT1, cancer cells, anti-cancer drugs, chemotherapy-induced senescence

  Published in Aging on June 17, 2021

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• Research PaperVolume 17, Issue 4pp 960-981

  Pharmacological recapitulation of the lean phenotype induced by the lifespan-extending sulfur amino acid-restricted diet

  Relevance score: 0.00

  Naidu B. Ommi, Dwight A.L. Mattocks, Karel Kalecký, Teodoro Bottiglieri, Sailendra N. Nichenametla

  Keywords: buthionine sulfoximine, thiols, serine, anti-obesity drugs, aging

  Published in Aging on April 7, 2025

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• Research PaperVolume 16, Issue 6pp 5149-5162

  A novel immune-related lncRNA signature predicts the prognosis and immune landscape in ccRCC

  Relevance score: 0.00

  Longlong Dai, Daen Pan, Jiafei Jin, Wenhui Lv

  Keywords: immune, lncRNA, ccRCC, drugs

  Published in Aging on March 13, 2024

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• Research PaperVolume 15, Issue 14pp 7038-7055

  Exploring molecular markers and drug candidates for colorectal cancer through comprehensive bioinformatics analysis

  Relevance score: 0.00

  Guangyao Li, JiangPeng Zhu, Lulu Zhai

  Keywords: colorectal cancer, WGCNA, biomarker, prognosis, drugs

  Published in Aging on July 18, 2023

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• Research PaperVolume 14, Issue 22pp 9243-9263

  System analysis based on the ER stress-related genes identifies WFS1 as a novel therapy target for colon cancer

  Relevance score: 0.00

  Xianguang Yang, Chaoyang Zhang, Cheng Yan, Liukai Ma, Jiahao Ma, Xiaoke Meng

  Keywords: COAD, ERSRGs, prognostic models, sensitive drugs, WFS1

  Published in Aging on November 28, 2022

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• Research PaperVolume 14, Issue 13pp 5571-5589

  A novel prognostic signature of metastasis-associated genes and personalized therapeutic strategy for lung adenocarcinoma patients

  Relevance score: 0.00

  Zhihao Wang, Yusi Liu, Xiaoqian Zhan, Xi Wang, Chao Zhang, Lingzhi Qin, Liwei Liu, Shenghui Qin

  Keywords: lung adenocarcinoma, metastasis, prognostic, signature, candidate drugs

  Published in Aging on July 12, 2022

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• Research PaperVolume 13, Issue 7pp 9991-10014

  Transcriptome and lipidome profile of human mesenchymal stem cells with reduced senescence and increased trilineage differentiation ability upon drug treatment

  Relevance score: 0.00

  Yue Chen, Xinglan An, Zengmiao Wang, Shuanghong Guan, Hongyu An, Qingyuan Huang, Haobo Zhang, Lin Liang, Bo Huang, Huiyu Wang, Min Lu, Huan Nie, Jun Wang, Xiangpeng Dai, Xin Lu

  Keywords: lipidomics, transcriptomics, hMSCs, aging, drugs

  Published in Aging on March 26, 2021

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• Research PaperVolume 12, Issue 20pp 19923-19937

  Influence of anti-osteoporosis treatments on the incidence of COVID-19 in patients with non-inflammatory rheumatic conditions

  Relevance score: 0.00

  Josep Blanch-Rubió, Natalia Soldevila-Domenech, Laura Tío, Jone Llorente-Onaindia, Manuel Ciria-Recasens, Luciano Polino, Alba Gurt, Rafael de la Torre, Rafael Maldonado, Jordi Monfort, the Covidmar Study Group

  Keywords: denosumab, zoledronate, calcium, vitamin D, anti-resorptive drugs, COVID-19

  Published in Aging on October 20, 2020

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