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• Research PaperVolume 6, Issue 1pp 26-34

  Clearance of senescent hepatocytes in a neoplastic-prone microenvironment delays the emergence of hepatocellular carcinoma

  Relevance score: 0.00

  Fabio Marongiu, Maria Paola Serra, Marcella Sini, Fabrizio Angius, Ezio Laconi

  Keywords: cell transplantation, tumor microenvironment, cell senescence, cell competition, liver repopulation, liver carcinogenesis

  Published in Aging on January 23, 2014

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• ReviewVolume 14, Issue 9pp 4176-4187

  Hallmarks of cancer and hallmarks of aging

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: oncology, carcinogenesis, geroscience, mTOR, rapamycin, hyperfunction theory

  Published in Aging on May 9, 2022

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• EditorialVolume 13, Issue 22pp 24477-24479

  Twists and turns in Kras-driven tumor initiation

  Relevance score: 0.00

  Yoshiaki Maru, Yoshitaka Hippo

  Keywords: organoid, carcinogenesis, KRAS, mouse model, pancreatic ductal adenocarcinoma

  Published in Aging on November 29, 2021

• Research PaperVolume 13, Issue 19pp 23149-23168

  Comprehensive analysis of aberrant alternative splicing related to carcinogenesis and prognosis of papillary thyroid cancer

  Relevance score: 0.00

  Xiaobo Zheng, Li Feng, Yunfan Yin, Chune Yu, Xiujing He, Jiao Zhu, Ming Zhang, Jing Yu, Mingqing Xu

  Keywords: papillary thyroid cancer, alternative splicing, carcinogenesis, prognosis, The Cancer Genome Atlas

  Published in Aging on October 8, 2021

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• Research PaperVolume 12, Issue 24pp 24651-24670

  Downregulated genes by silencing MYC pathway identified with RNA-SEQ analysis as potential prognostic biomarkers in gastric adenocarcinoma

  Relevance score: 0.00

  Jersey Heitor da Silva Maués, Helem Ferreira Ribeiro, Raquel de Maria Maués Sacramento, Rafael Maia de Sousa, Raíssa Pereira de Tommaso, Bruno Dourado Kovacs Machado Costa, Paulo Cardoso Soares, Paulo Pimentel Assumpção, Caroline de Fátima Aquino Moreira-Nunes, Rommel Mário Rodriguez Burbano

  Keywords: MYC, gastric carcinogenesis, distant metastases, prognosis, biomarkers

  Published in Aging on December 22, 2020

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• Research PaperVolume 11, Issue 11pp 3851-3863

  Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape

  Relevance score: 0.00

  Monica Serra, Fabio Marongiu, Maria Giuseppina Pisu, Mariangela Serra, Ezio Laconi

  Keywords: time restricted feeding, carcinogenesis, aging, tissue microenvironment

  Published in Aging on June 12, 2019

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• Research PaperVolume 6, Issue 12pp 1033-1048

  Stochastic modeling indicates that aging and somatic evolution in the hematopoietic system are driven by non-cell-autonomous processes

  Relevance score: 0.00

  Andrii I. Rozhok, Jennifer L. Salstrom, James DeGregori

  Keywords: hematopoiesis, carcinogenesis, leukemogenesis somatic evolution, fitness, driver mutation, microenvironment, adaptation

  Published in Aging on December 17, 2014

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• Research PaperVolume 17, Issue 1pp 97-115

  Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc^1638N/+ mice

  Relevance score: 0.00

  Kamendra Kumar, Bo-Hyun Moon, Santosh Kumar, Jerry Angdisen, Bhaskar V.S. Kallakury, Albert J. Fornace, Shubhankar Suman

  Keywords: senescence-associated secretory phenotype, senolytic agent, carcinogenesis, inflammation, β-catenin

  Published in Aging on January 8, 2025

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• Research PaperVolume 17, Issue 7pp 1624-1666

  Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer

  Relevance score: 0.00

  Su Yon Jung, Matteo Pellegrini, Xianglong Tan, Herbert Yu

  Keywords: epigenetic aging, pre-diagnostic DNA, DNA methylation–based aging marker, colorectal cancer, carcinogenesis, oophorectomy, diet, postmenopausal women

  Published in Aging on July 7, 2025

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• Research PaperVolume 13, Issue 11pp 15214-15239

  Pan-cancer analysis of the prognostic value of C12orf75 based on data mining

  Relevance score: 0.00

  Guangzhen Cai, Guannan Jin, Junnan Liang, Ganxun Li, Xiaoping Chen, Huifang Liang, Zeyang Ding

  Keywords: chromosome 12 open reading frame 75 (C12orf75), pan-cancer analysis, prognostic biomarker, tumor microenvironment, carcinogenesis

  Published in Aging on June 1, 2021

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• Research PaperVolume 12, Issue 22pp 23029-23046

  ERRα inhibitor acts as a potential agonist of PPARγ to induce cell apoptosis and inhibit cell proliferation in endometrial cancer

  Relevance score: 0.00

  Meimei Huang, Lili Chen, Xiaodan Mao, Guifen Liu, Yuqin Gao, Xiaoqing You, Min Gao, Jalid Sehouli, Pengming Sun

  Keywords: peroxisome proliferator-activated receptor-γ, estrogen-related receptor-α, endometrial cancer, carcinogenesis, prognosis

  Published in Aging on November 10, 2020

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• Theory ArticleVolume 10, Issue 10pp 2557-2569

  Aging and aging-associated diseases: a microRNA-based endocrine regulation hypothesis

  Relevance score: 0.00

  Samuil Umansky

  Keywords: geroscience, miRNA hormones, pituitary gland, sex-dependent differences, degeneration and carcinogenesis, Down syndrome

  Published in Aging on October 29, 2018

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• EditorialVolume 9, Issue 2pp 297-298

  Deubiquitination in cancer stem cells

  Relevance score: 0.00

  Julia M. Fraile, Diana Campos-Iglesias, José M. P. Freije

  Keywords: degradome, ubiquitin-specific protease, USP54, stem cells, carcinogenesis, metastasis

  Published in Aging on February 12, 2017

• Research PaperVolume 8, Issue 12pp 3390-3399

  Aging promotes neoplastic disease through effects on the tissue microenvironment

  Relevance score: 0.00

  Fabio Marongiu, Maria Paola Serra, Silvia Doratiotto, Marcella Sini, Maura Fanti, Erika Cadoni, Monica Serra, Ezio Laconi

  Keywords: aging, microenvironment, selection, pre-neoplastic hepatocytes, liver carcinogenesis

  Published in Aging on December 6, 2016

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• Research PaperVolume 3, Issue 2pp 148-157

  If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice

  Relevance score: 0.00

  Vladimir N. Anisimov, Lev M. Berstein, Irina G. Popovich, Mark A. Zabezhinski, Peter A. Egormin, Tatiana S. Piskunova, Anna V. Semenchenko, Margarita L. Tyndyk, Maria N. Yurova, Irina G. Kovalenko, Tatiana E. Poroshina

  Keywords: Metformin, age of initiation, biomarkers of aging, life extension, spontaneous carcinogenesis, mice

  Published in Aging on February 21, 2011

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• Research PaperVolume 2, Issue 12pp 945-958

  Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice

  Relevance score: 0.00

  Vladimir N. Anisimov, Tatiana S. Piskunova, Irina G. Popovich, Mark A. Zabezhinski, Margarita L. Tyndyk, Peter A. Egormin, Maria N. Yurova, Svetlana V. Rosenfeld, Anna V. Semenchenko, Irina G. Kovalenko, Tatiana E. Poroshina, Lev M. Berstein

  Keywords: metformin, biomarkers of aging, life extension, carcinogenesis, mice

  Published in Aging on December 14, 2010

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