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• Research PaperVolume 12, Issue 14pp 14556-14568

  TP53 somatic mutations are associated with poor survival in non-small cell lung cancer patients who undergo immunotherapy

  Relevance score: 0.00

  Liqin Zhao, Xiaofei Qu, Zhenhua Wu, Yuehua Li, Xiaowei Zhang, WeiJian Guo

  Keywords: TP53, somatic mutation, tumor mutation burden, immunotherapy, non-small cell lung cancer

  Published in Aging on July 22, 2020

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• Research PaperVolume 12, Issue 18pp 18676-18692

  Identification of genomic alterations and associated transcriptomic profiling reveal the prognostic significance of MMP14 and PKM2 in patients with pancreatic cancer

  Relevance score: 0.00

  Haiwei Wang, Xinrui Wang, Liangpu Xu, Yingying Lin, Ji Zhang, Hua Cao

  Keywords: pancreatic cancer, KRAS mutation, TP53 mutation, CDKN2A deletion, MMP14

  Published in Aging on September 17, 2020

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• Research PaperVolume 13, Issue 5pp 7517-7537

  Molecular characterization of long-term survivors of hepatocellular carcinoma

  Relevance score: 0.00

  Junwei Shen, Jing Hu, Jiawen Wu, Xiaoli Luo, Yanfei Li, Jue Li

  Keywords: hepatocellular carcinoma, prognostic marker, G1/S transition, CDK4, TP53 mutation

  Published in Aging on March 3, 2021

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• Research PaperVolume 8, Issue 2pp 345-365

  p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function

  Relevance score: 0.00

  Zijun Y. Xu-Monette, Shanxiang Zhang, Xin Li, Ganiraju C. Manyam, Xiao-xiao Wang, Yi Xia, Carlo Visco, Alexandar Tzankov, Li Zhang, Santiago Montes-Moreno, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Xiaoying Zhao, Michael B. Møller, Ben M. Parsons, Jane N. Winter, Miguel A. Piris, L. Jeffrey Medeiros, Ken H. Young

  Keywords: p63, DLBCL, p53, TP53 mutation, MDM2

  Published in Aging on February 14, 2016

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• Research PaperVolume 14, Issue 8pp 3365-3386

  Wild type and gain of function mutant TP53 can regulate the sensitivity of pancreatic cancer cells to chemotherapeutic drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 pathway inhibitors, nutraceuticals and alter metabolic properties

  Relevance score: 0.00

  James A. McCubrey, Akshaya K. Meher, Shaw M. Akula, Stephen L. Abrams, Linda S. Steelman, Michelle M. LaHair, Richard A. Franklin, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Fulvio Barbaro, Przemysław Duda, Agnieszka Gizak

  Keywords: TP53, targeted therapy, PDAC, chemotherapeutic drugs, metabolic properties

  Published in Aging on April 27, 2022

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• Research PaperVolume 14, Issue 6pp 2868-2879

  TP53/BRAF mutation as an aid in predicting response to immune-checkpoint inhibitor across multiple cancer types

  Relevance score: 0.00

  Jia-Zheng Cao, Gao-Sheng Yao, Fei Liu, Yi-Ming Tang, Peng-Ju Li, Zi-Hao Feng, Jun-Hang Luo, Jin-Huan Wei

  Keywords: immune-checkpoint inhibitor therapies, TP53, BRAF, prognosis, precision medicine

  Published in Aging on March 27, 2022

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• Research PaperVolume 12, Issue 11pp 10194-10210

  Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines

  Relevance score: 0.00

  William H. Chappell, Saverio Candido, Stephen L. Abrams, Shaw M. Akula, Linda S. Steelman, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Melchiorre Cervello, Giuseppe Montalto, Ferdinando Nicoletti, Massimo Libra, James A. McCubrey

  Keywords: TP53, DDR, rapamycin, RAF/MEK/ERK, collagen

  Published in Aging on June 3, 2020

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• Research PaperVolume 12, Issue 3pp 2777-2797

  TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer

  Relevance score: 0.00

  Shaw M. Akula, Peter P. Ruvolo, James A. McCubrey

  Keywords: PDAC, Aging, cancer, TP53, miR-34a, SERPINE1

  Published in Aging on January 27, 2020

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• EditorialVolume 8, Issue 6pp 1159-1160

  Targeting mutant p53 for cancer therapy

  Relevance score: 0.00

  Moshe Oren, Perry Tal, Varda Rotter

  Keywords: TP53, mutant p53 gain-of-function, peptide therapy, tumor suppressor, MDM2

  Published in Aging on June 26, 2016

• Research PaperVolume 13, Issue 2pp 1929-1946

  A TP53-based immune prognostic model for muscle-invasive bladder cancer

  Relevance score: 0.00

  Hongyan Li, Huayi Lu, Wanli Cui, Yufan Huang, Xuefei Jin

  Keywords: MIBC, TP53, immune prognostic model, immune response, immune checkpoints

  Published in Aging on December 15, 2020

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• Research PaperVolume 12, Issue 21pp 21518-21543

  Oncostatin M expression and TP53 mutation status regulate tumor-infiltration of immune cells and survival outcomes in cholangiocarcinoma

  Relevance score: 0.00

  Qi Liu, Tian Lan, Yuxuan Song, Jianpeng Cai, Xi Yu, Wei Chen

  Keywords: cholangiocarcinoma, OSM, immune infiltration, TP53, prognosis

  Published in Aging on November 7, 2020

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• Research PaperVolume 15, Issue 12pp 5569-5591

  Expression, prognostic value and mechanism of SP100 family in pancreatic adenocarcinoma

  Relevance score: 0.00

  Yunjie Duan, Yongxing Du, Yongrun Mu, Zongting Gu, Chengfeng Wang

  Keywords: pancreatic adenocarcinoma, SP100 family, TP53, M6A, biomarkers, prognosis, immune infiltration

  Published in Aging on June 22, 2023

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• Research PaperVolume 14, Issue 9pp 3782-3800

  Transcriptional expressions of hsa-mir-183 predicted target genes as independent indicators for prognosis in bladder urothelial carcinoma

  Relevance score: 0.00

  Ming Li, Da-Ming Xu, Shu-Bin Lin, Zheng-Liang Yang, Teng-Yu Xu, Jin-Huan Yang, Ze-Xin Lin, Ze-Kai Huang, Jun Yin

  Keywords: hsa-mir-183, predicted target gene, TP53, prognosis, bladder urothelial carcinoma

  Published in Aging on May 3, 2022

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• Research PaperVolume 8, Issue 10pp 2392-2406

  Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice

  Relevance score: 0.00

  Joohwee Kim, Vivek Vaish, Mingxiao Feng, Kevin Field, Ioulia Chatzistamou, Minsub Shim

  Keywords: premature aging, COX2, TP53, p16, prostaglandin

  Published in Aging on October 7, 2016

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• Research PaperVolume 13, Issue 8pp 11564-11594

  Comprehensive analysis of genomic and immunological profiles in Chinese and Western hepatocellular carcinoma populations

  Relevance score: 0.00

  Wei Li, Hong Wu, Xuewen Xu, Yange Zhang

  Keywords: hepatocellular carcinoma, heterogeneity, whole exome sequencing, tumor-infiltrating immune cell, TP53

  Published in Aging on April 18, 2021

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• Research PaperVolume 12, Issue 23pp 23778-23794

  Colon cancer combined with obesity indicates improved survival- research on relevant mechanism

  Relevance score: 0.00

  Zhou Yang, Xiyi Wei, Yitong Pan, Zhijun Min, Jingyuan Xu, Bo Yu

  Keywords: obesity, colon cancer, hypoxia, immune checkpoints, TP53

  Published in Aging on November 10, 2020

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• Research PaperVolume 8, Issue 12pp 3321-3340

  RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma

  Relevance score: 0.00

  Mingzhi Zhang, Zijun Y. Xu-Monette, Ling Li, Ganiraju C. Manyam, Carlo Visco, Alexandar Tzankov, Jing Wang, Santiago Montes-Moreno, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Michael B. Møller, Ben M. Parsons, Jane N. Winter, Miguel A. Piris, L. Jeffrey Medeiros, Lan V. Pham, Ken H. Young

  Keywords: NF-κB, p65, diffuse large B-cell lymphoma, TP53, GCB, gene expression profiling, proteasome inhibitor

  Published in Aging on December 8, 2016

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