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• Research PerspectiveVolume 1, Issue 7pp 664-668

  "Shping 2" different cellular localizations - a potential new player in aging processes

  Relevance score: 0.00

  Sascha Jakob, Joachim Altschmied, Judith Haendeler

  Keywords: Shp-2, nucleus, mitochondria, Telomerase Reverse Transcriptase

  Published in Aging on June 29, 2009

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• Research PaperVolume 16, Issue 18pp 12498-12509

  SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma

  Relevance score: 0.00

  Guojing Chai, Yingbo Nan, Haili Zhao, Qingchuan Hu

  Keywords: lung adenocarcinoma, SHP2, TAM, STAT3/STAT6 signaling pathway

  Published in Aging on May 14, 2024

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• Research PaperVolume 15, Issue 18pp 9877-9889

  Myeloid-specific knockout of SHP2 regulates PI3K/PLCγ signaling pathway to protect against early myocardial infarction injury

  Relevance score: 0.00

  Menglin Sha, Hongxing Li, Bingyan Guo, Xiaoyong Geng

  Keywords: SHP2, myocardial infarction, PI3K/PLCγ signaling pathway, endocytosis, inflammatory cytokine

  Published in Aging on September 26, 2023

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• Research PaperVolume 16, Issue 7pp 6334-6347

  Lactobacillus plantarum 45 activates SHP2 through inhibition of oxidative stress to regulate osteoblast and osteoclast differentiation

  Relevance score: 0.00

  Yaming Yang, Zheng Yan, Qi Xie, Yong Wang, Zhiying Liu, Min Lei

  Keywords: LP45, osteoporosis, SHP2, oxidative stress, osteoblast, osteoclast, inflammation

  Published in Aging on April 3, 2024

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• Research PaperVolume 16, Issue 4pp 3790-3802

  MUC1 promotes RIF by regulating macrophage ROS-SHP2 signaling pathway to up-regulate inflammatory response and inhibit angiogenesis

  Relevance score: 0.00

  Rongna Liu, Lin Chen, Xin Zhao, Lili Bao, Ruixia Wei, Xiaohua Wu

  Keywords: recurrent implantation failure, MUC1, ROS-SHP2 signaling pathway, inflammatory response

  Published in Aging on February 26, 2024

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• Research PaperVolume 16, Issue 6pp 5207-5223

  Allicin treats myocardial infarction in I/R through the promotion of the SHP2 axis to inhibit p-PERK-mediated oxidative stress

  Relevance score: 0.00

  Tong Gao, Mengru Liu, Dongliang Fu, Yajun Xue, Jiangquan Liao, Peng Yang, Xianlun Li

  Keywords: allicin, SHP2, I/R, oxidative stress, NLRP3

  Published in Aging on March 7, 2024

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• Research PaperVolume 16, Issue 5pp 4778-4788

  The low expression of miR-155 promotes the expression of SHP2 by inhibiting the activation of the ERK1/2 pathway and improves cell pyroptosis induced by I/R in mice

  Relevance score: 0.00

  Mengru Liu, Dongliang Fu, Tong Gao, Hong Jiang, Peng Yang, Xianlun Li

  Keywords: miR-155, SHP2, I/R, pyroptosis

  Published in Aging on March 6, 2024

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• Research PaperVolume 15, Issue 24pp 15525-15534

  M-CSF secreted by gastric cancer cells exacerbates the progression of gastric cancer by increasing the expression of SHP2 in tumor-associated macrophages

  Relevance score: 0.00

  Shaohua Zhang, Dongfei Ren, Huiyu Hou, Li Yao, Hufang Yuan

  Keywords: gastric cancer, tumor-associated macrophages, SHP2, GM-CSF, M-CSF

  Published in Aging on December 29, 2023

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• Research PaperVolume 15, Issue 23pp 14323-14332

  Specific knockout of notch-1 attenuates non-alcoholic fatty liver disease by promoting SHP2 phosphorylation

  Relevance score: 0.00

  Qian Gao, Yonggang Lu, Weiling Zhou

  Keywords: NAFLD, Notch-1, SHP2, inflammation, lipid deposition

  Published in Aging on December 13, 2023

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• Research PaperVolume 16, Issue 17pp 12335-12345

  Treatment of tumor-associated macrophages with PD-1 monoclonal antibodies affects vascular generation in cervical cancer via the PD-1/IRE1α/SHP2/HIF1α signaling pathway

  Relevance score: 0.00

  Xiaohui Hao, Weiwei Zhao, Xianyu Zhang, Xiurong Lu, Cong Wang, Zhilin Zhang

  Keywords: cervical cancer, tumor-associated macrophages, Sindilizumab, IRE1α, SHP2, HIF1α

  Published in Aging on August 28, 2024

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• Research Paper

  RGC32 promotes the progression of ccRCC by activating the NF-κB/SHP2/EGFR signaling pathway

  Relevance score: 0.00

  Jing Zhang, Yindi Sun, Kai Tang, Huirong Xu, Junjuan Xiao, Yan Li

  Keywords: RGC32, clear cell renal cell carcinoma, NF-κB/SHP2/EGFR signaling pathway

  Published in Aging on May 27, 2024

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• Research PaperVolume 16, Issue 2pp 1182-1191

  Myeloid-specific knockout of Notch-1 inhibits MyD88- and TRIF-mediated TLR signaling pathways by regulating oxidative stress-SHP2 axis, thus restraining aneurysm progression

  Relevance score: 0.00

  Yu Li, Ailin Guo, Jianlei Liu, Lijuan Tang, Lide Su, Zonghong Liu

  Keywords: abdominal aortic aneurysm, Notch1, macrophages, oxidative stress, SHP2, MyD88/TRIF/NF-κB signaling pathway

  Published in Aging on January 26, 2024

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• Research PaperVolume 16, Issue 17pp 12263-12276

  Excessive glucocorticoids combined with RANKL promote the differentiation of bone marrow macrophages (BMM) into osteoclasts and accelerate the progression of osteoporosis by activating the SYK/SHP2/NF-κB signaling pathway

  Relevance score: 0.00

  Hao Dong, Xiaocong Liu, Jiqiang Duan, Jing Zhang, Hao Liu, Tiehui Shen

  Keywords: osteoporosis, glucocorticoids, BMM, RANKL, SYK/SHP2/NF-κB signaling pathway

  Published in Aging on August 27, 2024

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• Research PerspectiveVolume 2, Issue 8pp 527-534

  Controlling SIRT1 expression by microRNAs in health and metabolic disease

  Relevance score: 0.00

  Jiyoung Lee, Jongsook Kim Kemper

  Keywords: FXR, SHP, miR-34a, p53, SIRT1, and metabolic syndrome

  Published in Aging on August 5, 2010

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