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• Research PaperVolume 10, Issue 11pp 3173-3184

  Effects of senescent secretory phenotype acquisition on human retinal pigment epithelial stem cells

  Relevance score: 0.00

  Raffaella Lazzarini, Michele Nicolai, Vittorio Pirani, Cesare Mariotti, Roberto Di Primio

  Keywords: AMD, RPESCs, age-related diseases, senescence, inflammation

  Published in Aging on November 16, 2018

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• Research PaperVolume 6, Issue 12pp 1064-1075

  Pathway activation profiling reveals new insights into Age-related Macular Degeneration and provides avenues for therapeutic interventions

  Relevance score: 0.00

  Evgeny Makarev, Charles Cantor, Alex Zhavoronkov, Anton Buzdin, Alexander Aliper, Antonei Benjamin Csoka

  Keywords: AMD, Age-related Macular Degeneration, gene expression, Transcriptome profiling, signaling pathway activation strength

  Published in Aging on December 22, 2014

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• Research PaperVolume 5, Issue 6pp 427-444

  Deficiency in the metabolite receptor SUCNR1 (GPR91) leads to outer retinal lesions

  Relevance score: 0.00

  Sandra Favret, Francois Binet, Eric Lapalme, Dominique Leboeuf, Jose Carbadillo, Tina Rubic, Emilie Picard, Gaelle Mawambo, Nicolas Tetreault, Jean-Sebastien Joyal, Sylvain Chemtob, Florian Sennlaub, John Paul SanGiovanni, Martin Guimond, Przemyslaw Sapieha

  Keywords: AMD, GPR91, geographic atrophy, microglia, succinate, metabolite receptor

  Published in Aging on June 17, 2013

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 12, Issue 10pp 9031-9040

  Role of Citicoline in an in vitro AMD model

  Relevance score: 0.00

  Sonali Nashine, M. Cristina Kenney

  Keywords: Citicoline, age-related macular degeneration (AMD), neuroprotection, RPE, mitochondria

  Published in Aging on May 29, 2020

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• Research PaperVolume 11, Issue 17pp 6691-6713

  PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

  Relevance score: 0.00

  Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney

  Keywords: age-related macular degeneration (AMD), RPE, PGC-1α, mitochondria, FDA-approved drugs

  Published in Aging on September 2, 2019

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• Research PaperVolume 12, Issue 7pp 6151-6171

  Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease

  Relevance score: 0.00

  Valérie Fontaine, Elodie Monteiro, Mylène Fournié, Elena Brazhnikova, Thinhinane Boumedine, Cécile Vidal, Christine Balducci, Louis Guibout, Mathilde Latil, Pierre J. Dilda, Stanislas Veillet, José-Alain Sahel, René Lafont, Serge Camelo

  Keywords: norbixin, retinal function, A2E, AMD, Stargardt disease

  Published in Aging on April 7, 2020

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• EditorialVolume 14, Issue 12pp 4933-4934

  Heavy lipids protect against heavy metals

  Relevance score: 0.00

  Joshua L. Dunaief

  Keywords: macular degeneration, AMD, oxidative stress, anti-oxidant, drug

  Published in Aging on June 22, 2022

• Research PaperVolume 14, Issue 10pp 4247-4269

  Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)

  Relevance score: 0.00

  Sonali Nashine, Pinchas Cohen, Junxiang Wan, M. Cristina Kenney

  Keywords: Humanin G, HNG, AMD, inflammation, age-related macular degeneration

  Published in Aging on May 16, 2022

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• Research PaperVolume 9, Issue 1pp 133-141

  Association of neovascular age-related macular degeneration with month and season of birth in Italy

  Relevance score: 0.00

  Antonio Longo, Alessandra Casuccio, Luca Pani, Teresio Avitabile, Salvatore Cillino, Maurizio G. Uva, Vincenza Bonfiglio, Andrea Russo, Guglielmo Parisi, Gilda Cennamo, Claudio Furino, Mariacristina Parravano, Entela Xoxi, Michele Reibaldi

  Keywords: neovascular age-related macular degeneration, neovascular AMD, anti-VEGF, season of birth, month of birth

  Published in Aging on December 19, 2016

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• Research PaperVolume 10, Issue 12pp 4241-4247

  Circulating insulin-like growth factor-1: a new clue in the pathogenesis of age-related macular degeneration

  Relevance score: 0.00

  Niccolò Castellino, Antonio Longo, Teresio Avitabile, Andrea Russo, Matteo Fallico, Vincenza Bonfiglio, Mario Damiano Toro, Robert Rejdak, Katarzyna Nowomiejska, Paolo Murabito, Claudio Furino, Michele Reibaldi

  Keywords: age‐related macular degeneration, neovascular AMD, IGF-1, anti‐VEGF, senescence, somatomedin C

  Published in Aging on December 29, 2018

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• Research PaperVolume 11, Issue 4pp 1177-1188

  Nutraceutical effects of Emblica officinalis in age-related macular degeneration

  Relevance score: 0.00

  Sonali Nashine, Raj Kanodia, Anthony B. Nesburn, Girish Soman, Baruch D. Kuppermann, M. Cristina Kenney

  Keywords: Emblica officinalis, Phyllanthus emblica, Indian gooseberry, Amla, nutraceutical, age-related macular degeneration, AMD

  Published in Aging on February 21, 2019

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• Research PaperVolume 10, Issue 6pp 1306-1323

  Loss of NAMPT in aging retinal pigment epithelium reduces NAD⁺ availability and promotes cellular senescence

  Relevance score: 0.00

  Ravirajsinh N. Jadeja, Folami L. Powell, Malita A. Jones, Jasmine Fuller, Ethan Joseph, Menaka C. Thounaojam, Manuela Bartoli, Pamela M. Martin

  Keywords: retinal pigment epithelium (RPE), aging, age-related macular degeneration (AMD), NAD+, NAMPT, senescence, SIRT1

  Published in Aging on June 12, 2018

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• Research PaperVolume 5, Issue 1pp 51-66

  Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: A novel culture model for dry AMD

  Relevance score: 0.00

  David M. Rabin, Richard L. Rabin, Timothy A. Blenkinsop, Sally Temple, Jeffrey H. Stern

  Keywords: RPE, oxidative stress, AMD

  Published in Aging on December 20, 2012

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• Research PaperVolume 12, Issue 16pp 16579-16596

  Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury

  Relevance score: 0.00

  Jing-Yao Song, Bin Fan, Lin Che, Yi-Ran Pan, Si-Ming Zhang, Ying Wang, Victoria Bunik, Guang-Yu Li

  Keywords: oxidative stress, ER stress, autophagy, AMD, PERK

  Published in Aging on August 28, 2020

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• Research PaperVolume 11, Issue 13pp 4323-4337

  HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration

  Relevance score: 0.00

  Shuo Sun, Bincui Cai, Yao Li, Wenqi Su, Xuzheng Zhao, Boteng Gong, Zhiqing Li, Xiaomin Zhang, Yalin Wu, Chao Chen, Stephen H. Tsang, Jin Yang, Xiaorong Li

  Keywords: A2E, HMGB1, Caveolin-1, RPE cell senescence, AMD

  Published in Aging on July 7, 2019

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• Research PerspectiveVolume 3, Issue 9pp 906-910

  Oxidation as “The Stress of Life”

  Relevance score: 0.00

  Nikolay L. Malinin, Xiaoxia Z. West, Tatiana V. Byzova

  Keywords: lipid oxidation, oxidative stress, aging, Toll-like receptor 2, AMD, angiogenesis, atherosclerosis

  Published in Aging on September 21, 2011

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