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Online ISSN: 1945-4589
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09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Pineal gland volume is associated with prevalent and incident isolated rapid eye movement sleep behavior disorder " which reported that pineal gland volume may be associated with the risk of isolated rapid eye movement (REM) sleep behavior…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum " which reported that during the process of aging, the retina exhibits chronic oxidative…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina " which reported that resveratrol was shown to not only increase mitochondrial quality and function, but also to suppress Akt/mTOR…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice " which reported that age-related chronic inflammation is a major risk factor for the incidence and…
09-08-2021
Aging-US published a Special Collection on Eye Disease which included " The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye " which reported that this study aimed to understand how complement expression…
08-22-2021
BUFFALO, NY-August 20, 2021 – Aging is indexed by Web of Science: Science Citation Index Expanded (abbreviated as Aging‑US). In June 2021, Web of Science (Clarivate Analytics) released their 2020 JCR Impact Factor. Aging is pleased to report that our 2020 impact factor is 5.682 . This number has increased from last…
08-09-2021
Aging-US published “ Acid ceramidase promotes senescent cell survival ” which reported that the authors identified acid ceramidase (ASAH1), a lysosomal enzyme that cleaves ceramide into sphingosine and fatty acid, as being highly elevated in senescent cells. This increase in ASAH1 levels in senescence is associated…
08-09-2021
Aging-US published " A model of the aged lung epithelium in idiopathic pulmonary fibrosis " which reported that Iiopathic pulmonary fibrosis (IPF) is an age-related disorder that carries a universally poor prognosis. By exposing mouse alveolar epithelial cells to repeated, low doses of bleomycin, instead of usual…
08-09-2021
Aging-US published " Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system " which reported that green tea extract (GTE) and cocoa-supplemented diets significantly improved survival rate of mice. GTE increased…
07-25-2021
Aging-US published " Differential responses of neurons, astrocytes, and microglia to G-quadruplex stabilization " which reported that while it is now firmly established that stabilized G4s lead to enhanced genomic instability in cancer cells, whether and how G4s contribute to genomic instability in brain cells is…
07-25-2021
Aging-US published " PirB functions as an intrinsic suppressor in hippocampal neural stem cells " which reported that neural stem cells play pivotal roles during prenatal development and throughout life. PirB expression increased with age during development, and its deficiency promoted neural stem cell proliferation…
07-25-2021
Aging-US published " HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression " which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay. Functionally, HMGA1 affected…
07-25-2021
Aging-US published " Identification of microenvironment related potential biomarkers of biochemical recurrence at 3 years after prostatectomy in prostate adenocarcinoma " which reported that the authors aimed to identify the potential prognostic genes in the prostate adenocarcinoma microenvironment and to estimate the…
07-25-2021
Aging-US published " Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1 " which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited…
07-25-2021
Aging-US published " Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma " which reported that there is still a lack of comprehensive analysis of the circular RNA -long non-coding RNA -miRNA-mRNA ceRNA…
07-25-2021
Aging-US published " Antrodia salmonea induces apoptosis and enhances cytoprotective autophagy in colon cancer cells " which reported that 3- -2,5-diphenyltetrazolium bromide assay revealed that AS showed a remarkable effect on cell viability in colon cancer cells; SW620, HCT116, and HT29. Annexin V/propidium iodide…
07-25-2021
Aging-US published " Cognition and action: a latent variable approach to study contributions of executive functions to motor control in older adults " which reported that Aging is associated with profound alterations in motor control that may be exacerbated by age-related executive functioning decline. However,…
07-25-2021
Aging-US published " miRNAs generated from Meg3-Mirg locus are downregulated during aging " which reported that Aging determines a multilevel functional decline and increases the risk for cardiovascular pathologies. The heart is one of the most affected organs in aged individuals, however little is known about the…
07-25-2021
Aging-US published " The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence " which reported that cellular senescence may be a side effect of chemotherapy and other anti-cancer treatments that may promote inflammation and paracrine secondary senescence in healthy…
07-25-2021
Aging-US published " Spatiotemporal dynamics of γH2AX in the mouse brain after acute irradiation at different postnatal days with special reference to the dentate gyrus of the hippocampus " which reported that, radiosensitivity of the different brain cells, including neurons, glial cells, cells in cerebrovascular…