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• Research PaperVolume 12, Issue 11pp 10827-10843

  High mutation load, immune-activated microenvironment, favorable outcome, and better immunotherapeutic efficacy in melanoma patients harboring MUC16/CA125 mutations

  Relevance score: 0.00

  Qinghua Wang, Yichen Yang, Meng Yang, Xiangchun Li, Kexin Chen

  Keywords: MUC16, tumor mutation load, immune microenvironment, survival outcome, immunotherapeutic efficacy

  Published in Aging on June 3, 2020

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• Research PaperVolume 13, Issue 6pp 8563-8587

  A novel panel based on immune infiltration and tumor mutational burden for prognostic prediction in hepatocellular carcinoma

  Relevance score: 0.00

  Chan Xie, Hewei Wu, Tao Pan, Xingrong Zheng, Xiaoan Yang, Genglin Zhang, Yunwen Lian, Jiaxin Lin, Liang Peng

  Keywords: tumor mutation burden, hepatocellular carcinoma, immune infiltration, neoplasm recurrence, vascular invasion

  Published in Aging on March 10, 2021

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• Research PaperVolume 12, Issue 3pp 2132-2141

  EP300 mutation is associated with tumor mutation burden and promotes antitumor immunity in bladder cancer patients

  Relevance score: 0.00

  Gongmin Zhu, Lijiao Pei, Yuan Li, Xin Gou

  Keywords: bladder cancer, EP300, tumor mutation burden, tumor-infiltrating immune cells, prognosis

  Published in Aging on February 3, 2020

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• Research PaperVolume 12, Issue 2pp 1577-1590

  PIK3CA gene mutations in the helical domain correlate with high tumor mutation burden and poor prognosis in metastatic breast carcinomas with late-line therapies

  Relevance score: 0.00

  Yu Tang, Jing Li, Ning Xie, Xiaohong Yang, Liping Liu, Hui Wu, Can Tian, Ying He, Xiao Wang, Qiongzhi He, Zhe-Yu Hu, Quchang Ouyang

  Keywords: metastatic breast cancers, PIK3CA mutations, helical domain, tumor mutation burden, ctDNA mutation profile

  Published in Aging on January 24, 2020

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• Research PaperVolume 12, Issue 2pp 1285-1303

  DNAH10 mutation correlates with cisplatin sensitivity and tumor mutation burden in small-cell lung cancer

  Relevance score: 0.00

  Man Li, Anqi Lin, Peng Luo, Weitao Shen, Dan Xiao, Lanying Gou, Jian Zhang, Linlang Guo

  Keywords: cisplatin, resistance, small cell lung cancer, DNAH10, tumor mutation burden

  Published in Aging on January 20, 2020

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• Research PaperVolume 13, Issue 8pp 11257-11280

  Prognostic analysis of tumor mutation burden and immune infiltration in hepatocellular carcinoma based on TCGA data

  Relevance score: 0.00

  Shaoqing Liu, Qianjie Tang, Jianwen Huang, Meixiao Zhan, Wei Zhao, Xiangyu Yang, Yong Li, Lige Qiu, Fujun Zhang, Ligong Lu, Xu He

  Keywords: hepatocellular carcinoma, tumor mutation burden, The Cancer Genome Atlas, immune infiltration

  Published in Aging on April 4, 2021

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• Research PaperVolume 13, Issue 6pp 9043-9055

  Mucin 4 mutation is associated with tumor mutation burden and promotes antitumor immunity in colon cancer patients

  Relevance score: 0.00

  Linglong Peng, Yang Li, Haitao Gu, Ling Xiang, Yongfu Xiong, Rong Wang, He Zhou, Jijian Wang

  Keywords: colon cancer, mucin 4, tumor mutation burden, tumor-infiltrating immune cells, prognosis

  Published in Aging on March 14, 2021

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• Research PaperVolume 12, Issue 19pp 19316-19324

  SYNE1 mutation may enhance the response to immune checkpoint blockade therapy in clear cell renal cell carcinoma patients

  Relevance score: 0.00

  Pengju Li, Jeifei Xiao, Bangfen Zhou, Jinhuan Wei, Junhang Luo, Wei Chen

  Keywords: SYNE1 mutation, tumor mutation burden, immune response, immune cells infiltration

  Published in Aging on October 8, 2020

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• Research PaperVolume 13, Issue 15pp 19696-19709

  Immune cell infiltration-associated signature in colon cancer and its prognostic implications

  Relevance score: 0.00

  Dan Deng, Xin Luo, Sifang Zhang, Zhijie Xu

  Keywords: prognosis, colon cancer, immune cell infiltration, tumor mutation burden, immunotherapy

  Published in Aging on August 4, 2021

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• Research PaperVolume 14, Issue 19pp 7824-7850

  DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in glioma

  Relevance score: 0.00

  Haitao Luo, Minhua Ye, Yan Hu, Miaojing Wu, Mengqi Cheng, Xingen Zhu, Kai Huang

  Keywords: DNA methylation, immune phenotypes, tumor mutation burden, immunotherapy, glioma

  Published in Aging on September 21, 2022

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• Research PaperVolume 12, Issue 24pp 26095-26120

  Identification and validation of an immune-related gene signature predictive of overall survival in colon cancer

  Relevance score: 0.00

  Xuening Zhang, Hao Zhao, Xuezhong Shi, Xiaocan Jia, Yongli Yang

  Keywords: colon cancer, immune-related genes, prognostic model, tumor mutation burden, immune checkpoints

  Published in Aging on December 19, 2020

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• Research PaperVolume 12, Issue 14pp 14556-14568

  TP53 somatic mutations are associated with poor survival in non-small cell lung cancer patients who undergo immunotherapy

  Relevance score: 0.00

  Liqin Zhao, Xiaofei Qu, Zhenhua Wu, Yuehua Li, Xiaowei Zhang, WeiJian Guo

  Keywords: TP53, somatic mutation, tumor mutation burden, immunotherapy, non-small cell lung cancer

  Published in Aging on July 22, 2020

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• Research PaperVolume 15, Issue 20pp 11389-11411

  Development of an immunogenic cell death prognostic signature for predicting clinical outcome and immune infiltration characterization in stomach adenocarcinoma

  Relevance score: 0.00

  Ye Liu, Lijia Zhang, Xue Lei, Xinyu Yin, Songjiang Liu

  Keywords: immunogenic cell death, molecular subtype, immune infiltration, prognostic value, tumor mutation burden

  Published in Aging on October 19, 2023

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• Research PaperVolume 12, Issue 21pp 21854-21873

  Three-gene risk model in papillary renal cell carcinoma: a robust likelihood-based survival analysis

  Relevance score: 0.00

  Yutao Wang, Kexin Yan, Jiaxing Lin, Jianfeng Wang, Zhenhua Zheng, Xinxin Li, Zhixiong Hua, Yuepeng Bu, Jianxiu Shi, Siqing Sun, Xuejie Li, Yang Liu, Jianbin Bi

  Keywords: papillary renal cell carcinoma (PRCC), robust risk model, weighted gene co-expression network analysis (WGCNA), immune infiltration, tumor mutation burden (TMB)

  Published in Aging on November 5, 2020

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• Research PaperVolume 12, Issue 14pp 14649-14676

  Identifying CpG methylation signature as a promising biomarker for recurrence and immunotherapy in non–small-cell lung carcinoma

  Relevance score: 0.00

  Ruihan Luo, Jing Song, Xiao Xiao, Zhengbo Xie, Zhiyuan Zhao, Wanfeng Zhang, Shiqi Miao, Yongyao Tang, Longke Ran

  Keywords: CpG methylation signature, recurrence, non–small-cell lung carcinoma, tumor mutation burden, immunotherapy

  Published in Aging on July 28, 2020

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• Research PaperVolume 11, Issue 22pp 10183-10202

  Development and validation of a metastasis-associated prognostic signature based on single-cell RNA-seq in clear cell renal cell carcinoma

  Relevance score: 0.00

  Chuanjie Zhang, Hongchao He, Xin Hu, Ao Liu, Da Huang, Yang Xu, Lu Chen, Danfeng Xu

  Keywords: single-cell RNA-seq, metastasis-associated genes, progression, tumor mutation burden, TCGA

  Published in Aging on November 20, 2019

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• Research PaperVolume 14, Issue 8pp 3464-3483

  Improving ovarian cancer treatment decision using a novel risk predictive tool

  Relevance score: 0.00

  Zhenyi Xu, Jiali Song, Lei Cao, Zhiwei Rong, Wenjie Zhang, Jia He, Kang Li, Yan Hou

  Keywords: tumor microenvironment, predictive factor, immunotherapy, targeted therapy, gene mutation

  Published in Aging on April 19, 2022

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• Research PaperVolume 13, Issue 8pp 11860-11876

  Genetic landscape of breast cancer and mutation tracking with circulating tumor DNA in Chinese women

  Relevance score: 0.00

  Yinghao Wang, Lizhi Lin, Linhong Li, Jialiang Wen, Yili Chi, Rutian Hao, Xuanxuan Dai, Yizuo Chen, Duping Huang, Yili Zhou, Jie You, Zhiqiang Ye, Hao Chen, Lingli Jin, Danxiang Chen, Fan Yang, Erjie Xia, Xueyan Ma, Fengyu Guo, Yunguang Tong, Min Zheng, Ouchen Wang

  Keywords: breast cancer, digital molecular identifier, circulating tumor DNA, mutation landscape, Chinese women

  Published in Aging on April 23, 2021

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• Research PaperVolume 16, Issue 17pp 12225-12238

  Melatonin downregulates angiogenesis and lymphangiogenesis by regulating tumor-associated macrophages via NLRP3 inflammasomes in lung adenocarcinoma

  Relevance score: 0.00

  Zhewei Zhao, Dongjie Ma, Yingzhi Qin, Yuan Xu, Shanqing Li, Hongsheng Liu

  Keywords: lung adenocarcinoma, tumor microenvironment, angiogenesis and lymphangiogenesis, tumor-associated macrophages, melatonin

  Published in Aging on September 3, 2024

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• Research PaperVolume 16, Issue 12pp 10252-10270

  Characterization of tumor endothelial cells (TEC) in gastric cancer and development of a TEC-based risk signature using single-cell RNA-seq and bulk RNA-seq data

  Relevance score: 0.00

  Meng Fan, Xiaofei Xu, Yu Hu

  Keywords: tumor endothelial cells, gastric cancer, risk signature, immunotherapy

  Published in Aging on June 12, 2024

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