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• Research PaperVolume 6, Issue 12pp 1064-1075

  Pathway activation profiling reveals new insights into Age-related Macular Degeneration and provides avenues for therapeutic interventions

  Relevance score: 0.00

  Evgeny Makarev, Charles Cantor, Alex Zhavoronkov, Anton Buzdin, Alexander Aliper, Antonei Benjamin Csoka

  Keywords: AMD, Age-related Macular Degeneration, gene expression, Transcriptome profiling, signaling pathway activation strength

  Published in Aging on December 22, 2014

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• Research PaperVolume 12, Issue 10pp 9311-9327

  Single nucleotide polymorphisms within the Wnt pathway predict the risk of bone metastasis in patients with non-small cell lung cancer

  Relevance score: 0.00

  Yiquan Xu, Hongru Li, Lihong Weng, Yanqin Qiu, Junqiong Zheng, Huaqiang He, Dongmei Zheng, Junfan Pan, Fan Wu, Yusheng Chen

  Keywords: Wnt signaling pathway, polymorphisms, bone metastasis, risk, biomarker

  Published in Aging on May 26, 2020

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• Research PaperVolume 16, Issue 18pp 12498-12509

  SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma

  Relevance score: 0.00

  Guojing Chai, Yingbo Nan, Haili Zhao, Qingchuan Hu

  Keywords: lung adenocarcinoma, SHP2, TAM, STAT3/STAT6 signaling pathway

  Published in Aging on May 14, 2024

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• Research PaperVolume 16, Issue 2pp 1845-1859

  Activation of Notch-1 signaling pathway in macrophages to secrete PD-L1 and regulate cytotoxicity of CAR-T cells in diffuse large B-cell lymphoma

  Relevance score: 0.00

  Weijing Li, Lili Wu, Chen Huang, Hongqing Ma, Lianjing Wang, Wei Liu, Lihong Liu

  Keywords: diffuse large B-cell lymphoma, macrophages, Notch-1/IRE1/XBP1s signaling pathway, PD-L1, CAR-T cells

  Published in Aging on January 22, 2024

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• Research PaperVolume 15, Issue 20pp 11471-11488

  The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study

  Relevance score: 0.00

  Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu

  Keywords: osteoporosis, Wnt signaling pathway, TERT, H₂O₂, bilateral ovariectomy

  Published in Aging on October 19, 2023

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• Research PaperVolume 6, Issue 8pp 675-689

  Metabolic clock generates nutrient anticipation rhythms in mTOR signaling

  Relevance score: 0.00

  Rohini V. Khapre, Sonal A. Patel, Anna A. Kondratova, Amol Chaudhary, Nikkhil Velingkaar, Marina P. Antoch, Roman V. Kondratov

  Keywords: Food anticipation, metabolism, mTOR signaling pathway, biological clocks, circadian clocks

  Published in Aging on August 26, 2014

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• Research PaperVolume 13, Issue 12pp 16667-16683

  Correlation of IL-6 and JAK2/STAT3 signaling pathway with prognosis of nasopharyngeal carcinoma patients

  Relevance score: 0.00

  Mengqi Zhuang, Xiaotong Ding, Wenli Song, Huimin Chen, Hui Guan, Yang Yu, Zicheng Zhang, Xinzhe Dong

  Keywords: IL-6, JAK2/STAT3 signaling pathway, clinicopathological features, prognosis, nasopharyngeal carcinoma

  Published in Aging on June 22, 2021

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• Research PaperVolume 10, Issue 7pp 1640-1648

  Caloric restriction effects on liver mTOR signaling are time-of-day dependent

  Relevance score: 0.00

  Richa Tulsian, Nikkhil Velingkaar, Roman Kondratov

  Keywords: metabolism, mTOR signaling pathway, aging, glucose, biological clocks, circadian clocks, insulin sensitivity, protein translation

  Published in Aging on July 16, 2018

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• Research PaperVolume 16, Issue 7pp 5916-5928

  Downregulating miRNA-199a-5p exacerbates fluorouracil-induced cardiotoxicity by activating the ATF6 signaling pathway

  Relevance score: 0.00

  Wei Wang, Liang Dong, Hengxu Lv, Yonghui An, Changwang Zhang, Zheng Zheng, Ying Guo, Li He, Libin Wang, Jinmei Wang, Xinlei Shi, Na Li, Mingqi Zheng

  Keywords: miRNA-199a-5p, ATF6 signaling pathway, fluorouracil, cardiotoxicity

  Published in Aging on March 25, 2024

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• Research PaperVolume 16, Issue 4pp 3790-3802

  MUC1 promotes RIF by regulating macrophage ROS-SHP2 signaling pathway to up-regulate inflammatory response and inhibit angiogenesis

  Relevance score: 0.00

  Rongna Liu, Lin Chen, Xin Zhao, Lili Bao, Ruixia Wei, Xiaohua Wu

  Keywords: recurrent implantation failure, MUC1, ROS-SHP2 signaling pathway, inflammatory response

  Published in Aging on February 26, 2024

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• Research PaperVolume 15, Issue 18pp 9877-9889

  Myeloid-specific knockout of SHP2 regulates PI3K/PLCγ signaling pathway to protect against early myocardial infarction injury

  Relevance score: 0.00

  Menglin Sha, Hongxing Li, Bingyan Guo, Xiaoyong Geng

  Keywords: SHP2, myocardial infarction, PI3K/PLCγ signaling pathway, endocytosis, inflammatory cytokine

  Published in Aging on September 26, 2023

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• Research PaperVolume 14, Issue 4pp 1865-1878

  miR-223-3p inhibits the progression of atherosclerosis via down-regulating the activation of MEK1/ERK1/2 in macrophages

  Relevance score: 0.00

  Daofeng You, Qiuge Qiao, Katsushige Ono, Mei Wei, Wenyun Tan, Cuihua Wang, Yangong Liu, Gang Liu, Mingqi Zheng

  Keywords: atherosclerosis, MEK1/ERK1/2 signaling pathway, inflammatory response, macrophages, miR-223-3p

  Published in Aging on February 24, 2022

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• Research PaperVolume 14, Issue 2pp 892-906

  The effect of QiangGuYin on osteoporosis through the AKT/mTOR/autophagy signaling pathway mediated by CKIP-1

  Relevance score: 0.00

  Yifeng Yuan, Jiangang Sun, Hang Zhou, Shen Wang, Caijian He, Tianpeng Chen, Mouhao Fang, Shaohua Li, Shifa Kang, Xiaosheng Huang, Binbin Tang, Bocheng Liang, Yingdelong Mao, Jianyou Li, Xiaolin Shi, Kang Liu

  Keywords: osteoporosis, CKIP-1, AKT/mTOR signaling pathway, apoptosis, QiangGuYin

  Published in Aging on January 24, 2022

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• Research PaperVolume 14, Issue 1pp 297-315

  TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer

  Relevance score: 0.00

  Guolin Zhang, Xin Luo, Zian Wang, Jianbin Xu, Wei Zhang, Engeng Chen, Qing Meng, Di Wang, Xuefeng Huang, Wei Zhou, Zhangfa Song

  Keywords: TIMP-2, ERK/MAPK signaling pathway, 5-Fu, drug resistance, colorectal cancer

  Published in Aging on January 12, 2022

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• Research PaperVolume 13, Issue 18pp 22556-22570

  MSCs enhances the protective effects of valsartan on attenuating the doxorubicin-induced myocardial injury via AngII/NOX/ROS/MAPK signaling pathway

  Relevance score: 0.00

  Dong Cheng, Wencheng Tu, Libo Chen, Haoren Wang, Qinfu Wang, Hainiang Liu, Ning Zhu, Weiyi Fang, Qin Yu

  Keywords: mesenchymal stem cells, doxorubicin, MAPK signaling pathway, valsartan, ROS

  Published in Aging on September 29, 2021

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• Research PaperVolume 12, Issue 15pp 15546-15555

  Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells

  Relevance score: 0.00

  Changying Shi, Jiamei Yang, Longmiao Hu, Boyi Liao, Liang Qiao, Weifeng Shen, Feng Xie, Guoqing Zhu

  Keywords: hepatocellular carcinoma, cancer stem cells, glycochenodeoxycholic acid, STAT3 signaling pathway

  Published in Aging on August 3, 2020

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• Research PaperVolume 16, Issue 13pp 10918-10930

  Luteolin targets the AGE-RAGE signaling to mitigate inflammation and ferroptosis in chronic atrophic gastritis

  Relevance score: 0.00

  Nailin Zhang, Pingping Chen, Xiaoyan Liang, Jianhui Sun, Qiquan Liu, Shengjiang Guan, Qiao Wang

  Keywords: luteolin, chronic atrophic gastritis, AGE-RAGE signaling pathway, ferroptosis

  Published in Aging on June 24, 2024

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• Research PaperVolume 16, Issue 16pp 12063-12072

  Mechanistic study of PD-L1 regulation of metastatic proliferation in non-small cell lung cancer through modulation of IRE1α/XBP-1 signaling pathway in tumor-associated macrophages

  Relevance score: 0.00

  Yi Wang, Lei Yang, Zezheng Liang, Ming Liu

  Keywords: PD-L1, macrophage, IRE1α/XBP-1 signaling pathway, non-small cell lung cancer, nivolumab, P-STAT3

  Published in Aging on August 24, 2024

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• Research PaperVolume 16, Issue 7pp 6510-6520

  has-miR-134-5p inhibits the proliferation and migration of glioma cells by regulating the BDNF/ERK signaling pathway

  Relevance score: 0.00

  Zeshang Guo, Pingxv An, Xinyu Hong

  Keywords: hsa-miR-134-5p, BDNF/ERK signaling pathway, MMP2/9, glioma

  Published in Aging on April 4, 2024

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• Research PaperVolume 16, Issue 5pp 4789-4810

  SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization

  Relevance score: 0.00

  Kai Feng, Ya Di, Meng Han, Weitao Yan, Yimin Wang

  Keywords: breast cancer cells, PI3K/AKT signaling pathway, macrophage polarization, epithelial mesenchymal transition, SORBS1

  Published in Aging on March 6, 2024

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