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• Research PaperVolume 15, Issue 24pp 15382-15401

  Proteomic analysis reveals the aging-related pathways contribute to pulmonary fibrogenesis

  Relevance score: 0.00

  Tingwei Zhang, Xinglong Yuan, Mengqi Jiang, Bo Liu, Nailiang Zhai, Qian Zhang, Xiaodong Song, Changjun Lv, Jinjin Zhang, Hongbo Li

  Keywords: aging, pulmonary fibrosis, proteomics, mechanical force, ferroptosis, autophagy, mitochondrial, senescence-inducing

  Published in Aging on December 22, 2023

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• Research PaperVolume 18, Issue 1pp 67-81

  P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts

  Relevance score: 0.00

  Shan Zhu, Jennifer Q Zhou, Kan Wang, Ming-lei Guo, Yan Y Sanders

  Keywords: senescence, fibroblast activation, p38 MAPK, lung fibrosis, H4K16Ac

  Published in Aging on March 3, 2026

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• Research PaperVolume 17, Issue 8pp 2113-2125

  DNMT1-mediated SPINT2 expression drives early senescence by suppressing c-Met signaling in human fibroblasts

  Relevance score: 0.00

  Min Seok Sim, Hae-Ok Byun, Seongki Min, Jiwon Hong, Su Bin Lim, Kyoung Sook Choi, Gyesoon Yoon

  Keywords: senescence, cellular senescence, aging, DNA methyltransferase 1 (DNMT1), serine protease inhibitor Kunitz type 2 (SPINT2)

  Published in Aging on August 20, 2025

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• Research PaperVolume 17, Issue 8pp 1929-1965

  Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures

  Relevance score: 0.00

  Sandip Kumar Patel, Joanna Bons, Jacob P. Rose, Jessie R. Chappel, Rebecca L. Beres, Mark A. Watson, Corey Webster, Jordan B. Burton, Roland Bruderer, Pierre-Yves Desprez, Lukas Reiter, Judith Campisi, Erin S. Baker, Birgit Schilling

  Keywords: proteomics, senescence, exosomes, data-independent acquisitions, aging

  Published in Aging on July 30, 2025

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• Research PaperVolume 17, Issue 6pp 1452-1465

  Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression

  Relevance score: 0.00

  Joseph Rupert, Zhanguo Gao, Yongmei Yu, Mikhail G. Kolonin

  Keywords: senescence, telomerase, myeloid, mesenchymal, endothelial

  Published in Aging on June 5, 2025

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• Research PaperVolume 17, Issue 1pp 97-115

  Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc^1638N/+ mice

  Relevance score: 0.00

  Kamendra Kumar, Bo-Hyun Moon, Santosh Kumar, Jerry Angdisen, Bhaskar V.S. Kallakury, Albert J. Fornace, Shubhankar Suman

  Keywords: senescence-associated secretory phenotype, senolytic agent, carcinogenesis, inflammation, β-catenin

  Published in Aging on January 8, 2025

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• Research PaperVolume 16, Issue 13pp 10670-10693

  Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice

  Relevance score: 0.00

  Hiromichi Tsushima, Hirobumi Tada, Azusa Asai, Mikako Hirose, Tohru Hosoyama, Atsushi Watanabe, Taro Murakami, Masataka Sugimoto

  Keywords: senescence, exercise, PEDF, myokine, COPD

  Published in Aging on June 26, 2024

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• Research PaperVolume 16, Issue 13pp 10749-10764

  Cathepsin L induces cellular senescence by upregulating CUX1 and p16^INK4a

  Relevance score: 0.00

  Yuwei Wu, Danli Jiang, Qing Liu, Shaoyang Yan, Xiuzhen Liu, Ting Wu, Wei Sun, Gang Li

  Keywords: senescence, atherosclerosis, p16^INK4a, Cathepsin L, CUX1

  Published in Aging on June 18, 2024

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• Research PaperVolume 16, Issue 9pp 7511-7522

  Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence

  Relevance score: 0.00

  Nicola Alessio, Alessia Ambrosino, Andrea Boggi, Domenico Aprile, Iole Pinto, Giovanni Galano, Umberto Galderisi, Giovanni Di Bernardo

  Keywords: senescence, apoptosis, UV light, public health

  Published in Aging on May 2, 2024

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• Research PaperVolume 16, Issue 9pp 7704-7732

  Immune cell senescence and exhaustion promote the occurrence of liver metastasis in colorectal cancer by regulating epithelial-mesenchymal transition

  Relevance score: 0.00

  Sen Lin, Lanyue Ma, Jiaxin Mo, Ruiqi Zhao, Jinghao Li, Mengjiao Yu, Mei Jiang, Lisheng Peng

  Keywords: senescence, exhaustion, colorectal cancer liver metastases, epithelium-mesenchymal transition, machine learning

  Published in Aging on April 26, 2024

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• Research PaperVolume 16, Issue 4pp 3068-3087

  Mapping the core senescence phenotype of primary human colon fibroblasts

  Relevance score: 0.00

  Namita Ganesh Hattangady, Kelly Carter, Brett Maroni-Rana, Ting Wang, Jessica Lee Ayers, Ming Yu, William M. Grady

  Keywords: senescence, senescence associated secretory phenotype, SASP, colorectal cancer, cancer

  Published in Aging on February 21, 2024

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• Research PaperVolume 16, Issue 4pp 3531-3553

  Senescence-related genes analysis in breast cancer reveals the immune microenvironment and implications for immunotherapy

  Relevance score: 0.00

  Hua Zhong, Lijie Chang, Shengbin Pei, Yakun Kang, Lili Yang, Yifan Wu, Nuo Chen, Yicheng Luo, Yixiao Zhou, Jiaheng Xie, Yiqin Xia

  Keywords: senescence, immune microenvironment, immunotherapy, risk signature, breast cancer

  Published in Aging on February 14, 2024

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• Research PaperVolume 16, Issue 3pp 2866-2886

  Comprehensive analysis of cellular senescence and immune microenvironment in papillary thyroid carcinoma

  Relevance score: 0.00

  Yinde Huang, Han Jiang, Guangwen Xu, Xin Li, Wenbin Chen, Yu Lun, Jian Zhang

  Keywords: papillary thyroid cancer, cellular senescence, aging, overall survival, TCGA

  Published in Aging on February 7, 2024

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• Research PaperVolume 15, Issue 24pp 14591-14606

  SRSF7 downregulation induces cellular senescence through generation of MDM2 variants

  Relevance score: 0.00

  Jiwon Hong, Seongki Min, Gyesoon Yoon, Su Bin Lim

  Keywords: senescence, cellular senescence, aging, alternative splicing, mouse double minute 2 homolog (MDM2)

  Published in Aging on December 29, 2023

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• Research PaperVolume 15, Issue 17pp 8576-8593

  Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes

  Relevance score: 0.00

  Mélina Georget, Anaïs Defois, Romain Guiho, Nina Bon, Sophie Allain, Cécile Boyer, Boris Halgand, Denis Waast, Gaël Grimandi, Alban Fouasson-Chailloux, Jérôme Guicheux, Claire Vinatier

  Keywords: senescence, osteoarthritis, etoposide, IL-1β, chondrocytes

  Published in Aging on September 1, 2023

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• Research PaperVolume 15, Issue 15pp 7408-7423

  Senescence-related gene c-Myc affects bladder cancer cell senescence by interacting with HSP90B1 to regulate cisplatin sensitivity

  Relevance score: 0.00

  Yaxuan Wang, Haixia Zhu, Haifei Xu, Yifan Qiu, Yonghong Zhu, Xiaolin Wang

  Keywords: HSP90B1, c-Myc, prognosis, senescence, cisplatin

  Published in Aging on July 10, 2023

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• Research PaperVolume 15, Issue 11pp 4576-4599

  Senescence and senotherapies in biliary atresia and biliary cirrhosis

  Relevance score: 0.00

  Giulia Jannone, Eliano Bonaccorsi Riani, Catherine de Magnée, Roberto Tambucci, Jonathan Evraerts, Joachim Ravau, Pamela Baldin, Caroline Bouzin, Axelle Loriot, Laurent Gatto, Anabelle Decottignies, Mustapha Najimi, Etienne Marc Sokal

  Keywords: senescence, senotherapy, liver, biliary cirrhosis, biliary atresia

  Published in Aging on May 18, 2023

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• Research PaperVolume 15, Issue 9pp 3331-3355

  In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers

  Relevance score: 0.00

  Parinya Samakkarnthai, Dominik Saul, Lei Zhang, Zaira Aversa, Madison L. Doolittle, Jad G. Sfeir, Japneet Kaur, Elizabeth J. Atkinson, James R. Edwards, Graham G. Russell, Robert J. Pignolo, James L. Kirkland, Tamar Tchkonia, Laura J. Niedernhofer, David G. Monroe, Nathan K. Lebrasseur, Joshua N. Farr, Paul D. Robbins, Sundeep Khosla

  Keywords: senescence, senolytics, aging, bone, bisphosphonates

  Published in Aging on May 7, 2023

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• Research PaperVolume 15, Issue 8pp 2824-2851

  Single-cell transcriptomic analysis uncovers diverse and dynamic senescent cell populations

  Relevance score: 0.00

  Noah Wechter, Martina Rossi, Carlos Anerillas, Dimitrios Tsitsipatis, Yulan Piao, Jinshui Fan, Jennifer L. Martindale, Supriyo De, Krystyna Mazan-Mamczarz, Myriam Gorospe

  Keywords: senescence, single-cell analysis, transcriptome

  Published in Aging on April 19, 2023

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• Research PaperVolume 15, Issue 7pp 2373-2394

  Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic

  Relevance score: 0.00

  Fares Al-Mansour, Abdullah Alraddadi, Buwei He, Anes Saleh, Marta Poblocka, Wael Alzahrani, Shaun Cowley, Salvador Macip

  Keywords: senescence, senolytics, HDAC, PI3K, CUDC-907

  Published in Aging on March 28, 2023

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