Volume 17, Issue 6

June 30, 2025pp 1371—1582

About the Cover

The cover features Figure 1 "Association between entropy, biological age, and biomarkers across neurological conditions" from Latumalea et al.

Research Perspective

Peto’s paradox’s relevance is off the scale

Mirre J.P. Simons

https://doi.org/10.18632/aging.206258pp 1371—1374

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Research Papers

Impact of waist-to-hip and waist-to-height ratios on physical performance: insights from the Longevity Check-up 8+ project

Anna Maria Martone, Elena Levati, Francesca Ciciariello, Vincenzo Galluzzo, Sara Salini, Riccardo Calvani, Emanuele Marzetti, Francesco Landi

https://doi.org/10.18632/aging.206260pp 1375—1385

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Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes

Yaowen Liu, Jingning Yu, Hao Hu, Shaoxia Pu, Haiyan Wu, Yunyu Ma, Wenhui Yang, Chongye Fang, Fei Sun, Haizhen Wang

https://doi.org/10.18632/aging.206261pp 1386—1404

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DoliClock: a lipid-based aging clock reveals accelerated aging in neurological disorders

Djakim Latumalea, Maximilian Unfried, Diogo Barardo, Jan Gruber, Brian K. Kennedy

https://doi.org/10.18632/aging.206266pp 1405—1428

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Spermidine supplementation and protein restriction protect from organismal and brain aging independently

YongTian Liang, Anja Krivograd, Sebastian J. Hofer, Laxmikanth Kollipara, Thomas Züllig, Albert Sickmann, Tobias Eisenberg, Stephan J. Sigrist

https://doi.org/10.18632/aging.206267pp 1429—1451

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Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression

Joseph Rupert, Zhanguo Gao, Yongmei Yu, Mikhail G. Kolonin

https://doi.org/10.18632/aging.206268pp 1452—1465

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Developing a quantitative estimate of muscle age acceleration by a novel phenotypic clock: cross-sectional study in healthy, middle-aged and older adults

Lucia Ventura, Antonella Cano, Marco Morrone, Gianluca Martinez, Anna Boi, Maria Grazia Catte, Beniamina Mercante, Nicola Loi, Oksana Yurchyshyn, Giovanni Fiorito, Giuliana Solinas, Sara Cruciani, Donatella Coradduzza, Margherita Maioli, Angelo Zinellu, Ciriaco Carru, Franca Deriu, Andrea Manca

https://doi.org/10.18632/aging.206269pp 1466—1483

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