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• Research PaperVolume 3, Issue 1pp 44-54

  Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats

  Relevance score: 0.00

  Anton M. Markovets, Valeriya B. Saprunova, Anna A. Zhdankina, Anzhella Zh. Fursova, Lora E. Bakeeva, Natalia G. Kolosova

  Keywords: age-related macular degeneration, OXYS rats, molecular mechanism of pathogenesis, vascular endothelial growth factor, pigment epithelium-derived factor

  Published in Aging on December 12, 2010

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• Research PaperVolume 10, Issue 6pp 1306-1323

  Loss of NAMPT in aging retinal pigment epithelium reduces NAD⁺ availability and promotes cellular senescence

  Relevance score: 0.00

  Ravirajsinh N. Jadeja, Folami L. Powell, Malita A. Jones, Jasmine Fuller, Ethan Joseph, Menaka C. Thounaojam, Manuela Bartoli, Pamela M. Martin

  Keywords: retinal pigment epithelium (RPE), aging, age-related macular degeneration (AMD), NAD+, NAMPT, senescence, SIRT1

  Published in Aging on June 12, 2018

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• Research PaperVolume 17, Issue 3pp 657-684

  Deciphering age-related transcriptomic changes in the mouse retinal pigment epithelium

  Relevance score: 0.00

  Sushil K. Dubey, Rashmi Dubey, Kyungsik Jung, Alvaro G. Hernandez, Mark E. Kleinman

  Keywords: transcriptome, retinal pigment epithelium, oxidative stress, inflammation, chronological aging

  Published in Aging on March 4, 2025

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• Research PaperVolume 13, Issue 8pp 11010-11025

  Obacunone protects retinal pigment epithelium cells from ultra-violet radiation-induced oxidative injury

  Relevance score: 0.00

  Da-Rui Huang, Chang-Ming Dai, Shu-Yan Li, Xiao-Feng Li

  Keywords: obacunone, UV radiation, retinal pigment epithelium cells, Nrf2 signaling, oxidative injury

  Published in Aging on February 1, 2021

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• Research PaperVolume 12, Issue 14pp 13905-13923

  Activation of C-reactive protein proinflammatory phenotype in the blood retinal barrier in vitro: implications for age-related macular degeneration

  Relevance score: 0.00

  Sara Romero-Vázquez, Alfredo Adán, Marc Figueras-Roca, Victor Llorenç, Mark Slevin, Gemma Vilahur, Lina Badimon, Andrew D Dick, Blanca Molins

  Keywords: age-related macular degeneration, retinal pigment epithelium, inflammation, C-reactive protein

  Published in Aging on July 16, 2020

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• Research PaperVolume 9, Issue 10pp 2052-2068

  PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation

  Relevance score: 0.00

  Dinusha Rajapakse, Mei Chen, Tim M. Curtis, Heping Xu

  Keywords: aging, multinucleation, retinal pigment epithelium, protein kinase C, p27kip1

  Published in Aging on October 9, 2017

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 13, Issue 18pp 22040-22058

  A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin

  Relevance score: 0.00

  Valérie Fontaine, Mylène Fournié, Elodie Monteiro, Thinhinane Boumedine, Christine Balducci, Louis Guibout, Mathilde Latil, José-Alain Sahel, Stanislas Veillet, Pierre J. Dilda, René Lafont, Serge Camelo

  Keywords: N-retinylidene-N-retinylethanolamine (A2E), norbixin, peroxisome proliferator-activated receptor (PPAR), retinal pigment epithelium (RPE), retinoic X receptor (RXR)

  Published in Aging on September 20, 2021

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• Research PaperVolume 2, Issue 1pp 28-42

  Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

  Relevance score: 0.00

  Shozo Sonoda, Parameswaran G. Sreekumar, Satoru Kase, Christine Spee, Stephen J Ryan, Ram Kannan, David R Hinton

  Keywords: retinal pigment epithelial cell, cell polarity, VEGF-A, PEDF, BMP-4, age-related macular degeneration

  Published in Aging on December 27, 2009

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• Research PaperVolume 15, Issue 18pp 9341-9357

  Palmitic acid promotes human retinal pigment epithelial cells migration by upregulating miR-222 expression and inhibiting NUMB

  Relevance score: 0.00

  Fengzhi Li, Chunling Lei, Ke Gong, Shuwei Bai, Lianyi Sun

  Keywords: palmitic acid, retinal pigment epithelial cells, migration, epithelial-mesenchymal transition, miR-222, NUMB

  Published in Aging on April 13, 2023

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• Research PaperVolume 15, Issue 9pp 3465-3479

  Palmitic acid–induced microRNA-143-5p expression promotes the epithelial–mesenchymal transition of retinal pigment epithelium via negatively regulating JDP2

  Relevance score: 0.00

  Yunlin Tian, Juan Shao, Shuwei Bai, Zhiguo Xu, Chunchao Bi

  Keywords: epithelial–mesenchymal transition (EMT), retinal pigment epithelial (RPE) cells, miR-143-5p, JDP2

  Published in Aging on April 25, 2023

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• Research PaperVolume 10, Issue 6pp 1380-1389

  The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells – implication in subretinal immune privilege in the aging eye

  Relevance score: 0.00

  Chang Luo, Jiawu Zhao, Mei Chen, Heping Xu

  Keywords: macrophages, retinal pigment epithelial cells, complement, aging, subretinal immune privilege

  Published in Aging on June 13, 2018

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• Research PaperVolume 13, Issue 10pp 14053-14064

  Role of LINC01592 in TGF-β1-induced epithelial-mesenchymal transition of retinal pigment epithelial cells

  Relevance score: 0.00

  Ying Su, Ziyan Tang, Feng Wang

  Keywords: long-chain non-coding RNA, retinal pigment epithelial cells, epithelial-mesenchymal transition

  Published in Aging on May 25, 2021

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• Research PaperVolume 13, Issue 24pp 25670-25693

  Chronobiological activity of cysteinyl leukotriene receptor 1 during basal and induced autophagy in the ARPE-19 retinal pigment epithelial cell line

  Relevance score: 0.00

  Andreas Koller, Julia Preishuber-Pflügl, Christian Runge, Anja-Maria Ladek, Susanne Maria Brunner, Ludwig Aigner, Herbert Reitsamer, Andrea Trost

  Keywords: autophagy, CysLTR1, LC3B, lysosomal degradation, retinal pigment epithelial cells

  Published in Aging on December 17, 2021

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• Research PaperVolume 8, Issue 5pp 889-898

  Autofluorescence as a measure of senescence in C. elegans: look to red, not blue or green

  Relevance score: 0.00

  Zachary Pincus, Travis C Mazer, Frank J Slack

  Keywords: autofluorescence, lipofuscin, age pigment, health

  Published in Aging on April 10, 2016

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• Research PerspectiveVolume 1, Issue 8pp 740-745

  What determines the switch between atrophic and neovascular forms ofage related macular degeneration? - the role of BMP4 induced senescence

  Relevance score: 0.00

  DanHong Zhu, Xuemei Deng, Jing Xu, David R Hinton

  Keywords: BMP4, age related macular degeneration, senescence, retinal pigment epithelial cell, oxidative stress

  Published in Aging on August 12, 2009

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