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Page: 1234 of 4

• Research PaperVolume 12, Issue 16pp 16621-16646

  Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype

  Relevance score: 0.00

  Xiangyong Li, Qian Zhou, Shuangshuang Wang, Ping Wang, Juan Li, Zhiwei Xie, Chang Liu, Jie Wen, Xunwei Wu

  Keywords: Rho kinase inhibitor, Y-27632, senescence, IGFBP-5, dermal fibroblast

  Published in Aging on August 25, 2020

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• Research PaperVolume 11, Issue 10pp 3250-3261

  A small molecular inhibitor of LRRK1 identified by homology modeling and virtual screening suppresses osteoclast function, but not osteoclast differentiation, in vitro

  Relevance score: 0.00

  Mingjue Si, Canjun Zeng, Helen Goodluck, Sandi Shen, Subburaman Mohan, Weirong Xing

  Keywords: LRRK1, bone resorption, bone formation, osteoclast, kinase inhibitor

  Published in Aging on May 21, 2019

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• EditorialVolume 7, Issue 12pp 1026-1027

  Fasting plus tyrosine kinase inhibitors in cancer

  Relevance score: 0.00

  Irene Caffa, Valter D. Longo, Alessio Nencioni

  Keywords: cancer, fasting, tyrosine kinase inhibitors, MAPK signaling, molecularly, targeted therapy

  Published in Aging on December 6, 2015

• Research PaperVolume 15, Issue 11pp 5066-5074

  Efficacy of first-line tyrosine kinase inhibitor between unresectable stage III and stage IV EGFR-mutated non-small cell lung cancer patients

  Relevance score: 0.00

  Yang Liu, Huan-Wei Liang, Xin-Bin Pan

  Keywords: non-small cell lung cancer, NSCLC, epidermal growth factor receptor, EGFR, tyrosine kinase inhibitor

  Published in Aging on June 8, 2023

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• Research PaperVolume 16, Issue 1pp 550-567

  Effectiveness and safety of afatinib, gefitinib, and erlotinib for treatment-naïve elderly patients with epidermal growth factor receptor-mutated advanced non-small-cell lung cancer: a multi-institute retrospective study

  Relevance score: 0.00

  Ling-Jen Hung, Ping-Chih Hsu, Cheng-Ta Yang, Chih-Hsi Scott Kuo, John Wen-Cheng Chang, Chen-Yang Huang, Ching-Fu Chang, Chiao-En Wu

  Keywords: elderly patients, epidermal growth factor receptor, tyrosine kinase inhibitor, non-small-cell lung cancer, real-world evidence

  Published in Aging on January 8, 2024

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• Research PaperVolume 13, Issue 11pp 15444-15458

  Alterations in the RTK/Ras/PI3K/AKT pathway serve as potential biomarkers for immunotherapy outcome of diffuse gliomas

  Relevance score: 0.00

  Song Han, Peng-Fei Wang, Hong-Qing Cai, Jing-Hai Wan, Shou-Wei Li, Ze-Huan Lin, Chun-Jiang Yu, Chang-Xiang Yan

  Keywords: gliomas, immunotherapy, small-molecule kinase inhibitors, bioinformatic analysis

  Published in Aging on June 8, 2021

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• Research PaperVolume 10, Issue 11pp 3574-3589

  Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK/ERK kinases

  Relevance score: 0.00

  Elena Y. Kochetkova, Galina I. Blinova, Olga A. Bystrova, Marina G. Martynova, Valeriy A. Pospelov, Tatiana V. Pospelova

  Keywords: senescence, mitochondria damage, lysosomes, autophagy, mTOR, MEK/ERK, kinase inhibitors

  Published in Aging on November 27, 2018

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• Research PaperVolume 16, Issue 1pp 857-871

  Treatment patterns and survival analysis in patients with unresectable stage III EGFR-mutated non-small cell lung cancer

  Relevance score: 0.00

  Huan-Wei Liang, Yang Liu, Xin-Bin Pan

  Keywords: non-small cell lung cancer, NSCLC, epidermal growth factor receptor, EGFR, tyrosine kinase inhibitor

  Published in Aging on January 11, 2024

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• EditorialVolume 9, Issue 7pp 1643-1644

  Synergistic SNGI-TKI combination against LSCs

  Relevance score: 0.00

  Xiaoyan Jiang

  Keywords: cancer stem cells, Icaritin (SNG162 and SNG1153), drug-resistance, tyrosine kinase inhibitors, CML, leukemic stem cells, BCR-ABL-T315I mutation

  Published in Aging on July 30, 2017

• Research PaperVolume 13, Issue 6pp 8248-8275

  Transcriptome profiling reveals target in primary myelofibrosis together with structural biology study on novel natural inhibitors regarding JAK2

  Relevance score: 0.00

  Weihang Li, Bin Yuan, Yingjing Zhao, Tianxing Lu, Shilei Zhang, Ziyi Ding, Dong Wang, Sheng Zhong, Guangxun Gao, Ming Yan

  Keywords: bioinformatics, inhibitor, Janus Kinase 2, virtual screening, discovery studio

  Published in Aging on March 3, 2021

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• Research PaperVolume 16, Issue 13pp 11072-11089

  AK7-deficiency reversal inhibits ccRCC progression and boosts anti-PD1 immunotherapy sensitivity

  Relevance score: 0.00

  Yigang Jin, Minjie Chen, Fei Chen, Zhaofeng Gao, Xiaoping Li, Lingyu Hu, Dandan Cai, Siqi Zhao, Zhengwei Song

  Keywords: adenylate kinase 7, ccRCC, immunotherapy, anti-PD1

  Published in Aging on July 5, 2024

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• Research PaperVolume 14, Issue 22pp 8886-8899

  Phosphoglycerate kinase 1 protects against ischemic damage in the gerbil hippocampus

  Relevance score: 0.00

  Kyu Ri Hahn, Hyun Jung Kwon, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang

  Keywords: phosphoglycerate kinase 1, lactate, ATP, Nrf2, H₂O₂, neuroprotection

  Published in Aging on October 18, 2022

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• Research PerspectiveVolume 2, Issue 4pp 231-237

  Living on the edge: stress and activation of stress responses promote lifespan extension

  Relevance score: 0.00

  Alice Zuin, David Castellano-Esteve, José Ayté, Elena Hidalgo

  Keywords: MAP kinase, aging, oxidative stress, protein kinase A, Sty1, Sck2

  Published in Aging on April 9, 2010

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• Research PerspectiveVolume 2, Issue 3pp 170-176

  MAP kinase phosphatase-1 - a new player at the nexus between sarcopenia and metabolic disease

  Relevance score: 0.00

  Rachel J. Roth Flach, Anton M. Bennett

  Keywords: MAP kinase phosphatase, MAP kinase, sarcopenia, metabolism

  Published in Aging on April 6, 2010

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• Research PaperVolume 1, Issue 6pp 557-572

  Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle

  Relevance score: 0.00

  Jonathan E. Nuss, James K. Amaning, C. Eric Bailey, James H. DeFord, Vincent L. Dimayuga, Jeffrey P. Rabek, John Papaconstantinou

  Keywords: Creatine kinase, creatine kinase structure, creatine kinase kinetics, 3-nitrotyrosine, carbonylation, skeletal muscle, aging

  Published in Aging on May 22, 2009

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• Priority Research PaperVolume 14, Issue 1pp 4-27

  AMP-activated protein kinase-dependent nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in senescent human diploid fibroblasts

  Relevance score: 0.00

  Jee Young Sohn, Hyeok-Jin Kwak, Ji Heon Rhim, Eui-Ju Yeo

  Keywords: glyceraldehyde-3-phosphate dehydrogenase, AMP-activated protein kinase, nuclear localization, senescence, human diploid fibroblasts

  Published in Aging on January 12, 2022

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• Research PaperVolume 13, Issue 14pp 18606-18619

  Obesity increases neuropathic pain via the AMPK-ERK-NOX4 pathway in rats

  Relevance score: 0.00

  Chang-Ning Fu, Hui Wei, Wen-Shuang Gao, Sha-Sha Song, Shou-Wei Yue, Yu-Juan Qu

  Keywords: extracellular-regulated kinase, obesity, neuropathic pain

  Published in Aging on July 29, 2021

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• Research PaperVolume 12, Issue 8pp 7511-7533

  Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia

  Relevance score: 0.00

  Yi-Jhu Lu, Yee-Jee Jan, Bor-Sheng Ko, Shu-Man Liang, Lujen Chen, Chih-Cheng Wu, Chih-Hui Chin, Cheng-Chin Kuo, Shaw-Fang Yet, Jun-Yang Liou

  Keywords: inflammation, intimal hyperplasia, Nik-related kinase, resveratrol, smooth muscle cell

  Published in Aging on April 24, 2020

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• Research PaperVolume 11, Issue 23pp 11329-11346

  Interplay of MKP-1 and Nrf2 drives tumor growth and drug resistance in non-small cell lung cancer

  Relevance score: 0.00

  Hongyan Wang, Kaihua Liu, Zhexu Chi, Xihang Zhou, Guoping Ren, Ren Zhou, Yinyan Li, Xiuwen Tang, Xiu Jun Wang

  Keywords: mitogen-activated protein kinase phosphatase 1, Nrf2, lung cancer

  Published in Aging on December 6, 2019

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• Research PaperVolume 11, Issue 2pp 697-706

  Chronic hyperglycemia regulates microglia polarization through ERK5

  Relevance score: 0.00

  Congde Chen, Suichun Wu, Zipu Hong, Xiaoming Chen, Xiaoou Shan, Shane Fischbach, Xiangwei Xiao

  Keywords: extracellular-signal-regulated kinase 5 (ERK5), diabetes, Alzheimer’s disease (AD), microglia, polarization

  Published in Aging on January 26, 2019

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