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• Research PaperVolume 11, Issue 10pp 3298-3314

  GDF10 inhibits proliferation and epithelial-mesenchymal transition in triple‐negative breast cancer via upregulation of Smad7

  Relevance score: 0.00

  Tian Zhou, Lei Yu, Jianjun Huang, Xueke Zhao, Yanwen Li, Yaxin Hu, Yu Lei

  Keywords: triple‐negative breast cancer, growth differentiation factor-10, epithelial-mesenchymal transition, invasion, apoptosis

  Published in Aging on May 31, 2019

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• ReviewVolume 13, Issue 8pp 12258-12272

  Growth differentiation factor 11: a “rejuvenation factor” involved in regulation of age-related diseases?

  Relevance score: 0.00

  Yuting Ma, Yongping Liu, Fang Han, Hongyan Qiu, Junfeng Shi, Na Huang, Ningning Hou, Xiaodong Sun

  Keywords: growth differentiation factor 11, GDF11, aging, transforming growth factor, age-related diseases, regeneration

  Published in Aging on April 22, 2021

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• Research PaperVolume 12, Issue 20pp 20024-20046

  GDF11 induces mild hepatic fibrosis independent of metabolic health

  Relevance score: 0.00

  Jan Frohlich, Kristina Kovacovicova, Tommaso Mazza, Maria R. Emma, Daniela Cabibi, Michelangelo Foti, Cyril Sobolewski, Jude A. Oben, Marion Peyrou, Francesc Villarroya, Maurizio Soresi, Rita Rezzani, Melchiorre Cervello, Francesca Bonomini, Anna Alisi, Manlio Vinciguerra

  Keywords: liver, NAFLD, NASH, fibrosis, growth differentiation factor 11

  Published in Aging on October 28, 2020

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• Research PaperVolume 12, Issue 13pp 12726-12739

  EZH2-mediated inhibition of microRNA-22 promotes differentiation of hair follicle stem cells by elevating STK40 expression

  Relevance score: 0.00

  Bingjie Cai, Min Li, Yunpeng Zheng, Yakun Yin, Fangcao Jin, Xuyang Li, Juan Dong, Xiaoyan Jiao, Xiaojun Liu, Kun Zhang, Dongqin Li, Junmin Wang, Guangwen Yin

  Keywords: hair growth, EZH2, microRNA-22, STK40, hair follicle stem cell differentiation

  Published in Aging on July 12, 2020

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• Research PaperVolume 13, Issue 1pp 1422-1439

  Functional characterization of DLK1/MEG3 locus on chromosome 14q32.2 reveals the differentiation of pituitary neuroendocrine tumors

  Relevance score: 0.00

  Yiyuan Chen, Hua Gao, Qian Liu, Weiyan Xie, Bin Li, Sen Cheng, Jing Guo, Qiuyue Fang, Haibo Zhu, Zhuang Wang, Jichao Wang, Chuzhong Li, Yazhuo Zhang

  Keywords: pituitary neuroendocrine tumors, DLK1/MEG3 locus, somatotroph adenomas, differentiation, growth hormone secreting

  Published in Aging on December 29, 2020

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• Research PaperVolume 17, Issue 10pp 2534-2551

  Growth hormone excess drives liver aging via increased glycation stress

  Relevance score: 0.00

  Parminder Singh, Anil Gautam, Marissa N. Trujillo, Praveen Singh, Lizbeth Enriquez Najera, James J. Galligan, Lisa Hensley, Pankaj Kapahi, Andrzej Bartke

  Keywords: aging, growth hormone, glycation stress, Gly-Low

  Published in Aging on October 3, 2025

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• EditorialVolume 14, Issue 8pp 3331-3332

  Chasing Methuselah: adult inducible GHRKO mice

  Relevance score: 0.00

  John J. Kopchick, Darlene E. Berryman, Edward O. List

  Keywords: growth hormone receptor, longevity, knockout, growth hormone

  Published in Aging on April 13, 2022

• Research PaperVolume 13, Issue 5pp 6765-6781

  Growth hormone ameliorates the age-associated depletion of ovarian reserve and decline of oocyte quality via inhibiting the activation of Fos and Jun signaling

  Relevance score: 0.00

  Chuanming Liu, Shiyuan Li, Yifan Li, Jiao Tian, Xiaoling Sun, Tianran Song, Guijun Yan, Lijun Ding, Haixiang Sun

  Keywords: growth hormone, aging, oocyte quality, meiosis, apoptosis

  Published in Aging on February 17, 2021

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• Research PaperVolume 12, Issue 14pp 13939-13957

  Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice

  Relevance score: 0.00

  Emanuela Agosti, Marilisa De Feudis, Elia Angelino, Roberta Belli, Maraiza Alves Teixeira, Ivan Zaggia, Edoardo Tamiso, Tommaso Raiteri, Andrea Scircoli, Flavio L. Ronzoni, Maurizio Muscaritoli, Andrea Graziani, Flavia Prodam, Maurilio Sampaolesi, Paola Costelli, Elisabetta Ferraro, Simone Reano, Nicoletta Filigheddu

  Keywords: growth hormone secretagogue receptor, skeletal muscle atrophy, sarcopenia, inflammaging, sarcobesity

  Published in Aging on July 26, 2020

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• Research PaperVolume 12, Issue 2pp 1377-1396

  The role of serum growth hormone and insulin-like growth factor-1 in adult humans brain morphology

  Relevance score: 0.00

  Taoyang Yuan, Jianyou Ying, Lu Jin, Chuzhong Li, Songbai Gui, Zhenye Li, Rui Wang, Zhentao Zuo, Yazhuo Zhang

  Keywords: growth hormone (GH), insulin-like growth factor-1 (IGF-1), brain structure, structural magnetic resonance imaging analysis

  Published in Aging on January 22, 2020

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• Research PaperVolume 7, Issue 9pp 616-628

  Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease

  Relevance score: 0.00

  Alexey Moskalev, Elizaveta Chernyagina, João Pedro de Magalhães, Diogo Barardo, Harikrishnan Thoppil, Mikhail Shaposhnikov, Arie Budovsky, Vadim E. Fraifeld, Andrew Garazha, Vasily Tsvetkov, Evgeny Bronovitsky, Vladislav Bogomolov, Alexei Scerbacov, Oleg Kuryan, Roman Gurinovich, Leslie C. Jellen, Brian Kennedy, Polina Mamoshina, Evgeniya Dobrovolskaya, Alex Aliper, Dmitry Kaminsky, Alex Zhavoronkov

  Keywords: growth hormone receptor (GHR), muscle-specific knockout, lifespan, aging, frailty, pathology, body composition

  Published in Aging on September 2, 2015

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• Research PaperVolume 7, Issue 7pp 500-512

  Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR−/− mice

  Relevance score: 0.00

  Edward O. List, Darlene E. Berryman, Yuji Ikeno, Gene B. Hubbard, Kevin Funk, Ross Comisford, Jonathan A. Young, Michael B. Stout, Tamar Tchkonia, Michal M. Masternak, Andrzej Bartke, James L. Kirkland, Richard A. Miller, John J. Kopchick

  Keywords: growth hormone receptor (GHR), muscle-specific knockout, lifespan, aging, frailty, pathology, body composition

  Published in Aging on June 29, 2015

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• Research PaperVolume 7, Issue 4pp 241-255

  Thyroxine modifies the effects of growth hormone in Ames dwarf mice

  Relevance score: 0.00

  Andrew Do, Vinal Menon, Xu Zhi, Adam Gesing, Denise S. Wiesenborn, Adam Spong, Liou Sun, Andrzej Bartke, Michal M. Masternak

  Keywords: growth hormone, insulin, thyroxine, Ames dwarf, longevity

  Published in Aging on April 22, 2015

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• Research PaperVolume 6, Issue 7pp 575-586

  Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice

  Relevance score: 0.00

  Michael B. Stout, Tamara Tchkonia, Tamar Pirtskhalava, Allyson K. Palmer, Edward O. List, Darlene E. Berryman, Ellen R. Lubbers, Carlos Escande, Adam Spong, Michal M. Masternak, Ann L. Oberg, Nathan K. LeBrasseur, Richard A. Miller, John J. Kopchick, Andrzej Bartke, James L. Kirkland

  Keywords: adipose tissue, aging, cellular senescence, growth hormone

  Published in Aging on July 20, 2014

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• ReviewVolume 1, Issue 4pp 357-362

  Growth and aging: a common molecular mechanism

  Relevance score: 0.00

  Mikhail V. Blagosklonny, Michael N. Hall

  Keywords: aging, growth, rapamycin, TOR, mitochondria

  Published in Aging on April 20, 2009

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• Research PaperVolume 17, Issue 8pp 2033-2062

  The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity

  Relevance score: 0.00

  Abhishek Guha, Ying Si, Reed Smith, Brijesh K. Singh, Benisa Zogu, Angad Yadav, Katherine A. Smith, Mohamed Kazamel, Nan Jiang, Ritchie Ho, Anna Thalacker-Mercer, Shaida A. Andrabi, Joao D. Tavares Da Silva Pereira, Juliana S. Salgado, Manasi Agrawal, Emina Horvat Velic, Peter H. King

  Keywords: fibroblast growth factor 21, β-Klotho, ALS biomarker, human skeletal muscle, motor neurons

  Published in Aging on August 9, 2025

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• Research PaperVolume 16, Issue 19pp 12673-12684

  Fibroblast growth factor 21 inversely correlates with survival in elderly population – the results of the Polsenior2 study

  Relevance score: 0.00

  Gabriela Handzlik, Aleksander J. Owczarek, Andrzej Więcek, Małgorzata Mossakowska, Tomasz Zdrojewski, Anna Chudek, Magdalena Olszanecka-Glinianowicz, Jerzy Chudek

  Keywords: fibroblast growth factor 21, aging, survival, population-based study, longevity

  Published in Aging on September 18, 2024

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• Research PaperVolume 13, Issue 2pp 2982-3009

  Excessive fibroblast growth factor 23 promotes renal fibrosis in mice with type 2 cardiorenal syndrome

  Relevance score: 0.00

  Huixin Hao, Siyuan Ma, Cankun Zheng, Qiancheng Wang, Hairuo Lin, Zhenhuan Chen, Jiahe Xie, Lin Chen, Kaitong Chen, Yuegang Wang, Xiaobo Huang, Shiping Cao, Wangjun Liao, Jianping Bin, Yulin Liao

  Keywords: fibroblast growth factor 23, myocardial infarction, cardiorenal dysfunction, fibrosis

  Published in Aging on January 15, 2021

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• Research PaperVolume 12, Issue 19pp 19399-19420

  Comprehensive analysis of TGF-β-induced mRNAs and ncRNAs in hepatocellular carcinoma

  Relevance score: 0.00

  Junnan Liang, Jingyu Liao, Tongtong Liu, Yu Wang, Jingyuan Wen, Ning Cai, Zhao Huang, Weiqi Xu, Ganxun Li, Zeyang Ding, Bixiang Zhang

  Keywords: transforming growth factor β, epithelial-mesenchymal transition, hepatocellular carcinoma, competing endogenous RNAs

  Published in Aging on October 4, 2020

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• Research PaperVolume 12, Issue 11pp 10951-10968

  Fibroblast growth factor 2 contributes to the effect of salidroside on dendritic and synaptic plasticity after cerebral ischemia/reperfusion injury

  Relevance score: 0.00

  Sisi Li, Yechen Lu, Daofang Ding, Zhenzhen Ma, Xiangxin Xing, Xuyun Hua, Jianguang Xu

  Keywords: salidroside, fibroblast growth factors, dendrite, synaptic plasticity, stroke

  Published in Aging on June 9, 2020

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