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• Research PaperVolume 8, Issue 8pp 1718-1734

  Biological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates

  Relevance score: 0.00

  Pasquale Picone, Silvia Vilasi, Fabio Librizzi, Marco Contardi, Domenico Nuzzo, Luca Caruana, Sara Baldassano, Antonella Amato, Flavia Mulè, Pier Luigi San Biagio, Daniela Giacomazza, Marta Di Carlo

  Keywords: Alzheimer’s disease, metformin, mitochondrial dysfunction, cell degeneration, mitochondrial pores, β-amyloid aggregation

  Published in Aging on July 28, 2016

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• Research PaperVolume 17, Issue 9pp 2369-2391

  Runx1 overexpression induces early onset of intervertebral disc degeneration

  Relevance score: 0.00

  Takanori Fukunaga, Martha Elena Diaz-Hernandez, John G. Heller, Changli Zhang, Hicham Drissi

  Keywords: cell senescence, aging, Runx1, nucleus pulposus, intervertebral disc degeneration

  Published in Aging on September 8, 2025

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• Research PaperVolume 11, Issue 22pp 10252-10265

  Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release

  Relevance score: 0.00

  Yingchao Han, Feng Yuan, Chao Deng, Fan He, Yan Zhang, Hongxing Shen, Zhi Chen, Lie Qian

  Keywords: intervertebral disc degeneration, annulus fibrosis stem cells, cell senescence, HMGB1, metformin

  Published in Aging on November 26, 2019

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• Research PaperVolume 15, Issue 24pp 14764-14790

  Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement

  Relevance score: 0.00

  Yingjing Zhao, Yuxue Mu, Yujia Zou, Zhijian He, Tianxing Lu, Xinhui Wang, Weihang Li, Bo Gao

  Keywords: intervertebral disc degeneration, weighted gene co-expression network analysis, Janus kinase family, high-throughput virtual screening, single-cell transcriptome

  Published in Aging on December 12, 2023

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• Research PaperVolume 14, Issue 10pp 4572-4585

  Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis

  Relevance score: 0.00

  Xiao-Bo Zhang, Si-Qi Xu, Yi-Geng Hui, Hai-Yu Zhou, Yi-Cun Hu, Rui-Hao Zhang, Xi-Dan Gao, Chang-Ming Zheng

  Keywords: lactotransferrin, intervertebral disc degeneration, bioinformatics, nucleus pulposus cell, mechanism

  Published in Aging on May 25, 2022

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• Research PaperVolume 16, Issue 9pp 8044-8069

  Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

  Relevance score: 0.00

  Shan Luo, Qiang Hu, Bo Jiang, Zhongyu Zhang, Dawei Sun

  Keywords: age-related macular degeneration, cellular senescence, programmed cell death, inflammatory response, molecular subtypes

  Published in Aging on May 10, 2024

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• Research PaperVolume 2, Issue 1pp 28-42

  Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

  Relevance score: 0.00

  Shozo Sonoda, Parameswaran G. Sreekumar, Satoru Kase, Christine Spee, Stephen J Ryan, Ram Kannan, David R Hinton

  Keywords: retinal pigment epithelial cell, cell polarity, VEGF-A, PEDF, BMP-4, age-related macular degeneration

  Published in Aging on December 27, 2009

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• Research PaperVolume 12, Issue 21pp 21971-21991

  CircGLCE alleviates intervertebral disc degeneration by regulating apoptosis and matrix degradation through the targeting of miR-587/STAP1

  Relevance score: 0.00

  Zhonghui Chen, Weibing Zhang, Ming Deng, Yaming Li, Yan Zhou

  Keywords: CircGLCE, intervertebral disc degeneration, apoptosis, nucleus pulposus cell, miR-587

  Published in Aging on November 6, 2020

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• Research PerspectiveVolume 1, Issue 8pp 740-745

  What determines the switch between atrophic and neovascular forms ofage related macular degeneration? - the role of BMP4 induced senescence

  Relevance score: 0.00

  DanHong Zhu, Xuemei Deng, Jing Xu, David R Hinton

  Keywords: BMP4, age related macular degeneration, senescence, retinal pigment epithelial cell, oxidative stress

  Published in Aging on August 12, 2009

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• Priority Research PaperVolume 16, Issue 22pp 13452-13504

  Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution

  Relevance score: 0.00

  Huige Tong, Xiaolong Guo, Macsue Jacques, Qi Luo, Nir Eynon, Andrew E. Teschendorff

  Keywords: DNA methylation, epigenetic clocks, cell-type deconvolution, biological aging, Alzheimer’s disease, obesity

  Published in Aging on December 29, 2024

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• Research PaperVolume 16, Issue 16pp 11796-11808

  2-Bromopalmitate treatment attenuates senescence phenotype in human adult cells - possible role of palmitoylation

  Relevance score: 0.00

  Adam Krzystyniak, Agata Gluchowska, Agata Pytyś, Magdalena Dudkowska, Tomasz Wójtowicz, Alicja Targonska, Dorota Janiszewska, Ewa Sikora, Grazyna Mosieniak

  Keywords: cell senescence, vascular smooth muscle cell, palmitoylation, 2-BP, DNA damage

  Published in Aging on August 23, 2024

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• Research PaperVolume 15, Issue 18pp 9572-9589

  Core fucosylation regulates alveolar epithelial cells senescence through activating of transforming growth factor-β pathway in pulmonary fibrosis

  Relevance score: 0.00

  Yu Jiang, Zhongzhen Wang, Jinying Hu, Wei Wang, Na Zhang, Lili Gao

  Keywords: cell senescence, idiopathic pulmonary fibrosis, core fucosylation, alveolar epithelial cell

  Published in Aging on September 18, 2023

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• EditorialVolume 15, Issue 7pp 2364-2366

  Senescent cells enhance ischemic aging in the female heart

  Relevance score: 0.00

  Daniele Torella, Nadia Salerno, Eleonora Cianflone

  Keywords: cell senescence, aging, cardiac stem cells, cardiac regeneration, female sex

  Published in Aging on March 23, 2023

• Research PaperVolume 14, Issue 19pp 7774-7793

  DNA methylation-regulated YTHDF2 correlates with cell migration and immune cell infiltration in glioma

  Relevance score: 0.00

  Xiulin Jiang, Xi Chen, Xiaobin Huang, Chunyan Wang, Chenyang Wang, Chenglong Pan, William C. Cho, Zhi Nie, Jun Pu, Weixiang Wang

  Keywords: cell proliferation, YTHDF2, DNA methylation, cell migration, immune infiltration

  Published in Aging on June 2, 2022

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• Research PaperVolume 13, Issue 24pp 25739-25762

  Small molecules for cell reprogramming: a systems biology analysis

  Relevance score: 0.00

  Anna Knyazer, Gabriela Bunu, Dmitri Toren, Teodora Bucaciuc Mracica, Yael Segev, Marina Wolfson, Khachik K. Muradian, Robi Tacutu, Vadim E. Fraifeld

  Keywords: cell reprogramming, chemically-induced pluripotency, chemical-protein interactions, protein-protein interaction networks, longevity pathways

  Published in Aging on December 17, 2021

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• Research PaperVolume 13, Issue 23pp 25466-25483

  Prognostic value of CDCA3 in kidney renal papillary cell carcinoma

  Relevance score: 0.00

  Hao Li, Mi Li, Caihong Yang, Fengjing Guo, Sisi Deng, Lixi Li, Tian Ma, Jiyuan Yan, Hua Wu, Xiaojuan Li

  Keywords: cell division cycle associated 3, kidney renal papillary cell carcinoma, prognostic values, differential expression, immune cell infiltration

  Published in Aging on December 14, 2021

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• Research PaperVolume 13, Issue 12pp 16485-16499

  Cell landscape atlas for patients with chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy constructed using single-cell RNA sequencing

  Relevance score: 0.00

  Ran Miao, Xingbei Dong, Juanni Gong, Yidan Li, Xiaojuan Guo, Jianfeng Wang, Qiang Huang, Ying Wang, Jifeng Li, Suqiao Yang, Tuguang Kuang, Jun Wan, Min Liu, Zhenguo Zhai, Jiuchang Zhong, Yuanhua Yang

  Keywords: chronic thromboembolic pulmonary hypertension, single-cell RNA sequencing, gene ontology enrichment analysis

  Published in Aging on June 21, 2021

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• Research PaperVolume 13, Issue 6pp 9056-9070

  Transplantation of olfactory ensheathing cells promotes the therapeutic effect of neural stem cells on spinal cord injury by inhibiting necrioptosis

  Relevance score: 0.00

  Xiaoyu Wang, Naifeng Kuang, Yuexia Chen, Guifeng Liu, Nan Wang, Fan’er Kong, Shouwei Yue, Zuncheng Zheng

  Keywords: cell transplantation, olfactory ensheathing cells, neural stem cell, necrioptosis, spinal cord injury

  Published in Aging on March 4, 2021

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• Research PaperVolume 12, Issue 14pp 14542-14555

  Higher expression of cell division cycle-associated protein 5 predicts poorer survival outcomes in hepatocellular carcinoma

  Relevance score: 0.00

  Shengzhong Hou, Xing Chen, Mao Li, Xing Huang, Haotian Liao, Bole Tian

  Keywords: cell division cycle-associated protein 5, prognosis, hepatocellular carcinoma, bioinformatics

  Published in Aging on July 21, 2020

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• Research PerspectiveVolume 12, Issue 11pp 10035-10040

  Microdose lithium reduces cellular senescence in human astrocytes - a potential pharmacotherapy for COVID-19?

  Relevance score: 0.00

  Tania Viel, Shankar Chinta, Anand Rane, Manish Chamoli, Hudson Buck, Julie Andersen

  Keywords: senolytics, lithium, COVID-19, cell senescence, chronic inflammation

  Published in Aging on June 13, 2020

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