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• Research PaperVolume 14, Issue 24pp 9877-9889

  SOX2-high cancer cells exhibit an aggressive phenotype, with increases in stemness, proliferation and invasion, as well as higher metabolic activity and ATP production

  Relevance score: 0.00

  Marta Mauro-Lizcano, Federica Sotgia, Michael P. Lisanti

  Keywords: cancer stem cells (CSCs), SOX2, FACS sorting, CSC isolation, stemness

  Published in Aging on December 22, 2022

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• Research PaperVolume 12, Issue 11pp 10162-10179

  First-in-class candidate therapeutics that target mitochondria and effectively prevent cancer cell metastasis: mitoriboscins and TPP compounds

  Relevance score: 0.00

  Béla Ózsvári, Federica Sotgia, Michael P. Lisanti

  Keywords: cancer stem-like cells (CSCs), mitochondrial inhibitors, treatment failure, breast cancer, metastasis prophylaxis

  Published in Aging on May 24, 2020

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• Research PaperVolume 10, Issue 11pp 3273-3282

  Spindle pole body component 25 regulates stemness of prostate cancer cells

  Relevance score: 0.00

  Feilun Cui, Huaming Tang, Jian Tan, Jianpeng Hu

  Keywords: cancer stem cells (CSCs), SPC25, prostate cancer (PrC)

  Published in Aging on November 8, 2018

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• Research PerspectiveVolume 11, Issue 3pp 1065-1068

  Hallmarks of the cancer cell of origin: Comparisons with “energetic” cancer stem cells (e-CSCs)

  Relevance score: 0.00

  Federica Sotgia, Marco Fiorillo, Michael P. Lisanti

  Keywords: cancer cell of origin, cancer stem cells (CSCs), senescence, metabolism, anti-oxidant response, tamoxifen resistance

  Published in Aging on February 13, 2019

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• Research PaperVolume 9, Issue 12pp 2610-2628

  Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy

  Relevance score: 0.00

  Bela Ozsvari, Gloria Bonuccelli, Rosa Sanchez-Alvarez, Richard Foster, Federica Sotgia, Michael P. Lisanti

  Keywords: Vitamin B2 (Riboflavin), DPI (Diphenyleneiodonium chloride), mitochondria, Mitoflavoscin, flavin enzymes, OXPHOS, cancer stem-like cells (CSCs)

  Published in Aging on December 16, 2017

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• Research PaperVolume 10, Issue 8pp 1867-1883

  Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways

  Relevance score: 0.00

  Gloria Bonuccelli, Federica Sotgia, Michael P. Lisanti

  Keywords: Matcha green tea, cancer stem-like cells (CSCs), proteomics analysis, metabolism, mitochondrial OXPHOS, glycolysis

  Published in Aging on August 23, 2018

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• Research PaperVolume 10, Issue 2pp 229-240

  Exploiting mitochondrial targeting signal(s), TPP and bis-TPP, for eradicating cancer stem cells (CSCs)

  Relevance score: 0.00

  Bela Ozsvari, Federica Sotgia, Michael P. Lisanti

  Keywords: tri-phenyl-phosphonium (TPP), cancer stem cells (CSCs), cancer therapy, mitochondrial targeting signal

  Published in Aging on February 19, 2018

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• Research PaperVolume 9, Issue 10pp 2098-2116

  A new mutation-independent approach to cancer therapy: Inhibiting oncogenic RAS and MYC, by targeting mitochondrial biogenesis

  Relevance score: 0.00

  Bela Ozsvari, Federica Sotgia, Michael P. Lisanti

  Keywords: RAS, MYC, cancer stem cells (CSCs), cancer therapy, mitochondrial oxidative stress

  Published in Aging on October 27, 2017

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• Research PaperVolume 16, Issue 11pp 9334-9349

  Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration

  Relevance score: 0.00

  Marta Mauro-Lizcano, Federica Sotgia, Michael P. Lisanti

  Keywords: mitophagy, BNIP3, BNIP3L(NIX), cancer stem cells (CSCs), flow cytometry (FACS)

  Published in Aging on June 4, 2024

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• Research PaperVolume 8, Issue 8pp 1593-1606

  Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)

  Relevance score: 0.00

  Marco Fiorillo, Rebecca Lamb, Herbert B. B. Tanowitz, Anna Rita Rita Cappello, Ubaldo E. E. Martinez-Outschoorn, Federica Sotgia, Michael P. P. Lisanti

  Keywords: bedaquiline, mitochondria, tumor-initiating cells (TICs), cancer stem-like cells (CSCs), drug repurposing

  Published in Aging on June 22, 2016

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• Research PaperVolume 14, Issue 23pp 9466-9483

  Identification of natural products and FDA-approved drugs for targeting cancer stem cell (CSC) propagation

  Relevance score: 0.00

  Gloria Bonuccelli, Federica Sotgia, Michael P. Lisanti

  Keywords: cancer stem cells, drug screening, natural compounds, FDA approved drugs, mammospheres

  Published in Aging on December 1, 2022

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• EditorialVolume 13, Issue 17pp 20854-20855

  Aging, stem cells and cancer updated

  Relevance score: 0.00

  Osama A. Elkashty, Arvind Hariharan, Simon D. Tran

  Keywords: cancer stem cells, tumorigenesis, epigenetic, head and neck cancer, signaling pathways

  Published in Aging on September 11, 2021

• ReviewVolume 11, Issue 23pp 11770-11792

  Cancer stem cells-driven tumor growth and immune escape: the Janus face of neurotrophins

  Relevance score: 0.00

  Viviana Triaca, Valentina Carito, Elena Fico, Pamela Rosso, Marco Fiore, Massimo Ralli, Alessandro Lambiase, Antonio Greco, Paola Tirassa

  Keywords: cancer stem cells, NGF, immunesurveillance, tumor microenvironment, cancer innervation

  Published in Aging on December 7, 2019

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• EditorialVolume 9, Issue 7pp 1643-1644

  Synergistic SNGI-TKI combination against LSCs

  Relevance score: 0.00

  Xiaoyan Jiang

  Keywords: cancer stem cells, Icaritin (SNG162 and SNG1153), drug-resistance, tyrosine kinase inhibitors, CML, leukemic stem cells, BCR-ABL-T315I mutation

  Published in Aging on July 30, 2017

• Research PaperVolume 14, Issue 14pp 5908-5924

  microRNA-497 prevents pancreatic cancer stem cell gemcitabine resistance, migration, and invasion by directly targeting nuclear factor kappa B 1

  Relevance score: 0.00

  Qiangfeng Yu, Zhe Xiu, Yizeng Jian, Jianyin Zhou, Xiaopeng Chen, Xiang Chen, Chunxiang Chen, Hongbao Chen, Sijia Yang, Libo Yin, Wenlong Zeng

  Keywords: microRNA-497, nuclear factor kappa B 1, pancreatic cancer, cancer stem cells, gemcitabine

  Published in Aging on July 25, 2022

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• Research PaperVolume 13, Issue 8pp 11170-11187

  The critical role of peroxiredoxin-2 in colon cancer stem cells

  Relevance score: 0.00

  Linglong Peng, Yongfu Xiong, Rong Wang, Ling Xiang, He Zhou, Zhongxue Fu

  Keywords: colon cancer, colon cancer stem cells, peroxiredoxin-2, metastasis, chemoresistance

  Published in Aging on March 26, 2021

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• EditorialVolume 9, Issue 8pp 1847-1848

  Targeting NFκB signaling in GD2⁺ BCSCs

  Relevance score: 0.00

  Khoa Nguyen, V. Lokesh Battula

  Keywords: breast cancer stem cells, BCSC, GD2, Triple negative breast cancer, NFκB signaling, BMS345541, ST8SIA1, GD3 synthase

  Published in Aging on August 3, 2017

• Research PaperVolume 12, Issue 13pp 12771-12782

  HOTAIR expands the population of prostatic cancer stem-like cells and causes Docetaxel resistance via activating STAT3 signaling

  Relevance score: 0.00

  Ning Wang, Yaodong Jiang, Shidong Lv, Haoran Wen, Dehua Wu, Qiang Wei, Qiang Dang

  Keywords: HOTAIR, prostatic cancer stem-like cells, STAT3, Docetaxel resistance

  Published in Aging on July 13, 2020

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• Research PaperVolume 13, Issue 7pp 9748-9765

  Long non-coding RNA DPP10-AS1 exerts anti-tumor effects on colon cancer via the upregulation of ADCY1 by regulating microRNA-127-3p

  Relevance score: 0.00

  Gang Liu, Hui Zhao, Qiang Song, Guangmeng Li, Shuying Lin, Sheng Xiong

  Keywords: colon cancer, cancer stem cells, long non-coding RNA DPP10-AS1, microRNA-127-3p, adenylate cyclase 1

  Published in Aging on March 19, 2021

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• EditorialVolume 9, Issue 5pp 1353-1354

  Patient-derived cells modeling pediatric glioma

  Relevance score: 0.00

  Anna Wenger, Susanna Larsson, Helena Carén

  Keywords: DNA methylation, pediatric, glioblastoma, cancer stem cells, immunodeficient mice

  Published in Aging on May 8, 2017