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• Research PaperVolume 16, Issue 8pp 7217-7248

  Hepatocyte-specific METTL3 ablation by Alb-iCre mice (GPT), but not by Alb-Cre mice (JAX), resulted in acute liver failure (ALF) and postnatal lethality

  Relevance score: 0.00

  Shihao Huang, Yingchun Li, Bingjie Wang, Zhihao Zhou, Yonglong Li, Lingjun Shen, Jinge Cong, Liuxin Han, Xudong Xiang, Jiawei Xia, Danhua He, Zhanlin Zhao, Ying Zhou, Qiwen Li, Guanqi Dai, Hanzhang Shen, Taoyan Lin, Aibing Wu, Junshuang Jia, Dong Xiao, Jing Li, Wentao Zhao, Xiaolin Lin

  Keywords: METTL3, Alb-iCre mice (GPT), Alb-Cre mice (JAX), acute liver failure (ALF), postnatal lethality

  Published in Aging on April 22, 2024

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• Research PaperVolume 15, Issue 12pp 5550-5568

  Mettl3-mediated m⁶A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression

  Relevance score: 0.00

  Guanqi Dai, Shihao Huang, Yonglong Li, Xueyi Tu, Jiawei Xia, Zhihao Zhou, Wanyi Chen, Ao Zhang, Jintao Lin, Yingchun Li, Danhua He, Taoyan Lin, Jinge Cong, Ye Lei, Liuxin Han, Zhenxia Yao, Weiwei Liu, Ying Zhou, Qiwen Li, Jing Li, Yuqin Zhang, Aibing Wu, Dong Xiao, Wanshan Wang, Wentao Zhao, Junshuang Jia, Xiaolin Lin

  Keywords: NAFLD, m⁶A modification, epigenetics, lipid metabolism, Mettl3

  Published in Aging on June 16, 2023

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• Research PaperVolume 13, Issue 19pp 23108-23118

  METTL3 regulates hippocampal gene transcription via N6-methyladenosine methylation in sevoflurane-induced postoperative cognitive dysfunction mouse

  Relevance score: 0.00

  Baiqing He, Jian Wang

  Keywords: POCD, m6A methylation, METTL3, sevoflurane, hippocampus

  Published in Aging on October 5, 2021

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• Research PaperVolume 13, Issue 18pp 22332-22344

  METTL3-mediated m6A modification of KIF3C-mRNA promotes prostate cancer progression and is negatively regulated by miR-320d

  Relevance score: 0.00

  Honggui Ma, Facai Zhang, Quliang Zhong, Jianquan Hou

  Keywords: METTL3, m6A, KIF3C, miR-320d, prostate cancer

  Published in Aging on September 19, 2021

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• Research PaperVolume 12, Issue 21pp 21638-21659

  Analysis of METTL3 and METTL14 in hepatocellular carcinoma

  Relevance score: 0.00

  Xiangxiang Liu, Jian Qin, Tianyi Gao, Chenmeng Li, Xiaoxiang Chen, Kaixuan Zeng, Mu Xu, Bangshun He, Bei Pan, Xueni Xu, Yuqin Pan, Huiling Sun, Tao Xu, Shukui Wang

  Keywords: METTL3, METTL14, N6-methyladenosine, hepatocellular carcinoma, bioinformatics analysis

  Published in Aging on November 6, 2020

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• Research PaperVolume 12, Issue 9pp 8137-8150

  Overexpression of METTL3 attenuates high-glucose induced RPE cell pyroptosis by regulating miR-25-3p/PTEN/Akt signaling cascade through DGCR8

  Relevance score: 0.00

  Xu Zha, Xiaoting Xi, Xinyu Fan, Minjun Ma, Yuanping Zhang, Yanni Yang

  Keywords: METTL3, miR-25-3p, m6A, pyroptosis, PTEN

  Published in Aging on May 4, 2020

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• Research PaperVolume 16, Issue 2pp 1237-1248

  Silencing of METTL3 prevents the proliferation, migration, epithelial-mesenchymal transition, and renal fibrosis of high glucose-induced HK2 cells by mediating WISP1 in m6A-dependent manner

  Relevance score: 0.00

  Yuanzhen Chen, Ping Li, Mei Lin, Ying Jiang, Guiping Tan, Lianfang Huang, Dan Song

  Keywords: diabetic nephropathy, high glucose, METTL3, WISP1, m6A modification

  Published in Aging on January 29, 2024

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• Research PaperVolume 12, Issue 24pp 24967-24982

  HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification

  Relevance score: 0.00

  Zhi Yang, Xiaodi Jiang, Deming Li, Xiaofeng Jiang

  Keywords: gastric cancer, Hepatitis B X-interacting protein, METTL3, N6-methyladenosine methylation, MYC

  Published in Aging on October 13, 2020

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• Research PaperVolume 14, Issue 6pp 2548-2557

  Maslinic acid protects against pressure-overload-induced cardiac hypertrophy by blocking METTL3-mediated m⁶A methylation

  Relevance score: 0.00

  Ming Fang, Jun Deng, Qiangping Zhou, Zhengbang Hu, Lixia Yang

  Keywords: myocardial hypertrophy, maslinic acid (MA), N6-methyladenosine (m⁶A), methyltransferase-like 3 (METTL3)

  Published in Aging on March 28, 2022

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• Research PaperVolume 13, Issue 19pp 23361-23375

  piRNA-36741 regulates BMP2-mediated osteoblast differentiation via METTL3 controlled m6A modification

  Relevance score: 0.00

  Jianmin Liu, Ming Chen, Longyang Ma, Xingbo Dang, Gongliang Du

  Keywords: piRNA-36741, METTL3, BMP2, BMSCs, osteogenic differentiation, osteoporosis

  Published in Aging on October 13, 2021

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• Research PaperVolume 13, Issue 8pp 12224-12238

  Methylation of microRNA-338-5p by EED promotes METTL3-mediated translation of oncogene CDCP1 in gastric cancer

  Relevance score: 0.00

  Fangbin Zhang, Yan Yan, Xinguang Cao, Jinping Zhang, Yingxia Li, Changqing Guo

  Keywords: EED, methylation, microRNA-338-5p, METTL3, CDCP1

  Published in Aging on April 21, 2021

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• Research PaperVolume 13, Issue 3pp 4357-4369

  The hepatic microenvironment promotes lung adenocarcinoma cell proliferation, metastasis, and epithelial–mesenchymal transition via METTL3-mediated N6-methyladenosine modification of YAP1

  Relevance score: 0.00

  Xue-Feng Ni, Quan-Qin Xie, Jie-Min Zhao, Yan-jie Xu, Mei Ji, Wen-Wei Hu, Jun Wu, Chang-Ping Wu

  Keywords: adenocarcinoma, liver inflammatory microenvironment, METTL3, m6A, YAP1

  Published in Aging on January 20, 2021

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• Research PaperVolume 13, Issue 16pp 20661-20683

  METTL21B is a prognostic biomarker and potential therapeutic target in low-grade gliomas

  Relevance score: 0.00

  Xin Shu, Xinquan Li, Xiaochen Xiang, Qiang Wang, Qingming Wu

  Keywords: eukaryotic translation elongation factor 1A (eEF1A), methyltransferase, METTL21B, low grade glioma, prognosis

  Published in Aging on August 26, 2021

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