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The cover features Figure 1 "Low MUC4 expression is associated with poor survival in CRC patients" from Pothuraju et al.

Volume 14, Issue 5

15 March, 2022
pp 2016—2435

About the Cover

The cover features Figure 1 "Low MUC4 expression is associated with poor survival in CRC patients" from Pothuraju et al.


Explore This Issue

Editorials

Targeting proteostasis maintenance and autophagy in senescence

Valentin L’Hôte, Carl Mann, Jean-Yves Thuret,
https://doi.org/10.18632/aging.203941 pp 2016—2017
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Sex matters in Alzheimer’s disease?

Sheeja Navakkode, Toh Hean Ch’ng, Sreedharan Sajikumar,
https://doi.org/10.18632/aging.203950 pp 2018—2019
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Commentary

As predicted by hyperfunction theory, rapamycin treatment during development extends lifespan

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.203937 pp 2020—2024
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Priority Research Papers

Depletion of transmembrane mucin 4 (Muc4) alters intestinal homeostasis in a genetically engineered mouse model of colorectal cancer

Ramesh Pothuraju, Priya Pai, Sanjib Chaudhary, Jawed A. Siddiqui, Jesse L. Cox, Sukhwinder Kaur, Satyanarayana Rachagani, Hemant K. Roy, Michael Bouvet, Surinder K. Batra,
https://doi.org/10.18632/aging.203935 pp 2025—2046
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Cell immortalization facilitates prelamin A clearance by increasing both cell proliferation and autophagic flux

Carlos González-Blanco, Patricia Marqués, Jesús Burillo, Beatriz Jiménez, Gema García, Manuel Benito, Carlos Guillén,
https://doi.org/10.18632/aging.203943 pp 2047—2061
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Research Papers

COVID-19
Association of active immunotherapy with outcomes in cancer patients with COVID-19: a systematic review and meta-analysis

Chang Cao, Xinyan Gan, Xiaolin Hu, Yonglin Su, Yu Zhang, Xingchen Peng,
https://doi.org/10.18632/aging.203945 pp 2062—2080
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Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B

Deepak Kumar, Manoj K. Kashyap, Zhe Yu, Ide Spaanderman, Reymundo Villa, Thomas J. Kipps, James J. La Clair, Michael D. Burkart, Januario E. Castro,
https://doi.org/10.18632/aging.203924 pp 2081—2100
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Pathway-based metabolomics study of sarcopenia-related traits in two US cohorts

Qi Zhao, Hui Shen, Jiawang Liu, Chi-Yang Chiu, Kuan-Jui Su, Qing Tian, David Kakhniashvili, Chuan Qiu, Lan-Juan Zhao, Zhe Luo, Hong-Wen Deng,
https://doi.org/10.18632/aging.203926 pp 2101—2112
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Human endothelial cells promote arsenic-transformed lung epithelial cells to induce tumor growth and angiogenesis through interleukin-8 induction

Lei Zhao, Yi-Fang Wang, Jie Liu, Bing-Hua Jiang, Ling-Zhi Liu,
https://doi.org/10.18632/aging.203930 pp 2113—2130
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Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells

Kristie Kim, Tesfahun Dessale Admasu, Alexandra Stolzing, Amit Sharma,
https://doi.org/10.18632/aging.203931 pp 2131—2147
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Parkinson’s disease and cancer: a systematic review and meta-analysis on the influence of lifestyle habits, genetic variants, and gender

Joon Yan Selene Lee, Jing Han Ng, Seyed Ehsan Saffari, Eng-King Tan,
https://doi.org/10.18632/aging.203932 pp 2148—2173
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Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis

Carly A. Bobak, Abhimanyu, Harini Natarajan, Tanmay Gandhi, Sandra L. Grimm, Tomoki Nishiguchi, Kent Koster, Santiago Carrero Longlax, Qiniso Dlamini, Jacquiline Kahari, Godwin Mtetwa, Jeffrey D. Cirillo, James O’Malley, Jane E. Hill, Cristian Coarfa, Andrew R. DiNardo,
https://doi.org/10.18632/aging.203936 pp 2174—2193
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Tonsil mesenchymal stem cells-derived extracellular vesicles prevent submandibular gland dysfunction in ovariectomized rats

Ji Min Kim, Jeong Hun Kim, Keunyoung Kim, Sung-Chan Shin, Yong-Il Cheon, Hyung Sik Kim, Jin-Choon Lee, Eui-Suk Sung, Minhyung Lee, Gi-Cheol Park, Byung-Joo Lee,
https://doi.org/10.18632/aging.203947 pp 2194—2209
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Circular RNA circ_0001006 aggravates cardiac hypertrophy via miR-214-3p/PAK6 axis

Xuefeng Lin, Liqin Zhang, Wei Zhang, Xinjun Lei, Qun Lu, Aiqun Ma,
https://doi.org/10.18632/aging.203461 pp 2210—2220
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Impact of the food grade heat-killed probiotic and postbiotic oral lozenges in oral hygiene

Chiao-Wen Lin, Yi-Tzu Chen, Hsieh-Hsun Ho, Yi-Wei Kuo, Wen-Yang Lin, Jui-Fen Chen, Jia-Hung Lin, Cheng-Ruei Liu, Chi-Huei Lin, Yao-Tsung Yeh, Ching-Wei Chen, Yu-Fen Huang, Chen-Hung Hsu, Pei-Shan Hsieh, Shun-Fa Yang,
https://doi.org/10.18632/aging.203923 pp 2221—2238
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The association between osteoporosis medications and lowered all-cause mortality after hip or vertebral fracture in older and oldest-old adults: a nationwide population-based study

Chia-Chun Li, Jason C. Hsu, Fu-Wen Liang, Yin-Fan Chang, Ching-Ju Chiu, Chih-Hsing Wu,
https://doi.org/10.18632/aging.203927 pp 2239—2251
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Downregulation of ATP binding cassette subfamily a member 10 acts as a prognostic factor associated with immune infiltration in breast cancer

Pei-Yi Chu, Yen-Dun Tony Tzeng, Kuan-Hao Tsui, Ching-Yu Chu, Chia-Jung Li,
https://doi.org/10.18632/aging.203933 pp 2252—2267
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A comprehensive analysis of FOX family in HCC and experimental evidence to support the oncogenic role of FOXH1

Xiwu Ouyang, Lemeng Feng, Lei Yao, Jingyu Zhang, Yao Xiao, Guodong Liu, Gewen Zhang, Zhiming Wang,
https://doi.org/10.18632/aging.203934 pp 2268—2286
View Abstract PDF Full-Text How to Cite Special Collection on Cancer and mTOR

MafK accelerates Salmonella mucosal infection through caspase-3 activation

Shiyao Xu, Guiqiu Hu, Di Wu, Xingchi Kan, Hisashi Oishi, Satoru Takahashi, Shoupeng Fu, Juxiong Liu, Chuan Zhang,
https://doi.org/10.18632/aging.203938 pp 2287—2303
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Downregulation of ZC3H13 by miR-362-3p/miR-425-5p is associated with a poor prognosis and adverse outcomes in hepatocellular carcinoma

Shuang Wu, Shihai Liu, Yongxian Cao, Geng Chao, Peng Wang, Huazheng Pan,
https://doi.org/10.18632/aging.203939 pp 2304—2319
View Abstract PDF Full-Text How to Cite Special Collection on Tumor Suppressors

Polo-like kinases as potential targets and PLK2 as a novel biomarker for the prognosis of human glioblastoma

Yiming Ding, Hanjie Liu, Chuanbao Zhang, Zhaoshi Bao, Shuqing Yu,
https://doi.org/10.18632/aging.203940 pp 2320—2334
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Decrease in ovarian reserve through the inhibition of SIRT1-mediated oxidative phosphorylation

Lu Guo, Xiaocheng Liu, Hua Chen, Weigui Wang, Chao Gu, Bin Li,
https://doi.org/10.18632/aging.203942 pp 2335—2347
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Functional implications of aging-related lncRNAs for predicting prognosis and immune status in glioma patients

Guangying Zhang, Yanyan Li, Na Li, Liang-Fang Shen, Zhanzhan Li,
https://doi.org/10.18632/aging.203944 pp 2348—2366
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Centrosomal protein 290 is a novel prognostic indicator that modulates liver cancer cell ferroptosis via the Nrf2 pathway

Yiru Shan, Guang Yang, Qiuhong Lu, Xiangyu Hu, Dongwei Qi, Yehan Zhou, Yin Xiao, Li Cao, Fuhua Tian, Qi Pan,
https://doi.org/10.18632/aging.203946 pp 2367—2382
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Establishing a cancer driver gene signature-based risk model for predicting the prognoses of gastric cancer patients

Jun Chen, Chao Zhou, Ying Liu,
https://doi.org/10.18632/aging.203948 pp 2383—2399
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Manual therapy regulates oxidative stress in aging rat lumbar intervertebral discs through the SIRT1/FOXO1 pathway

Chongjie Yao, Guangxin Guo, Ruixin Huang, Cheng Tang, Qingguang Zhu, Yanbin Cheng, Lingjun Kong, Jun Ren, Min Fang,
https://doi.org/10.18632/aging.203949 pp 2400—2417
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miRNA-29a inhibits atherosclerotic plaque formation by mediating macrophage autophagy via PI3K/AKT/mTOR pathway

Weihua Shao, Suxing Wang, Xiaoxi Wang, Lixia Yao, Xiaoye Yuan, Dai Huang, Bonan Lv, Yuquan Ye, Hongyuan Xue,
https://doi.org/10.18632/aging.203951 pp 2418—2431
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Corrections

Correction for: circUBAP2 exacerbates malignant capabilities of NSCLC by targeting KLF4 through miR-3182 modulation

Guanying Zheng, Jianyuan Huang, Wenshu Chen, Peilin You, Yun Ding, Pengjie Tu,
https://doi.org/10.18632/aging.203928 pp 2432—2433
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Correction for: Calycosin stimulates the proliferation of endothelial cells, but not breast cancer cells, via a feedback loop involving RP11-65M17.3, BRIP1 and ERα

Yong Wang, Wei Xie, Mengyue Hou, Jing Tian, Xing Zhang, Qianyao Ren, Yue Huang, Jian Chen,
https://doi.org/10.18632/aging.203953 pp 2434—2435
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