Volume 14, Issue 21

November 15, 2022pp 8582—8881

About the Cover

The cover features Figure 7 " IGF1 gene therapy effect on the activation state of microglia" from Dolcetti et al.

Editorial

Enhanced lysosome biogenesis ameliorates neurodegenerative diseases

Wenlong Xue, Yang Li

https://doi.org/10.18632/aging.204389pp 8582—8584

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Research Papers

Abnormal myocardial enzymes in the prediction of mortality and hypertension in COVID-19 patients: a retrospective study

Shuang Sha, Min Liu, Miaomiao Sun, Long Xiao, Qing Chang, Ying Chen, Jie Huang

https://doi.org/10.18632/aging.204362pp 8585—8594

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ESR1 dysfunction triggers neuroinflammation as a critical upstream causative factor of the Alzheimer’s disease process

Junying Liu, Shouli Yuan, Xinhui Niu, Robbie Kelleher, Helen Sheridan

https://doi.org/10.18632/aging.204359pp 8595—8614

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IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons

Franco Juan Cruz Dolcetti, Eugenia Falomir-Lockhart, Francisco Acuña, Macarena Lorena Herrera, Sofia Cervellini, Claudio Gustavo Barbeito, Daniela Grassi, Maria-Angeles Arevalo, María José Bellini

https://doi.org/10.18632/aging.204360pp 8615—8632

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Epigallocatechin-3-gallate protects porcine oocytes against post-ovulatory aging through inhibition of oxidative stress

Dongjie Zhou, Ming-Hong Sun, Wen-Jie Jiang, Xiao-Han Li, Song-Hee Lee, Geun Heo, Ying-Jie Niu, Sun A. Ock, Xiang-Shun Cui

https://doi.org/10.18632/aging.204368pp 8633—8644

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The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability

Savitha S. Sharma, W. Jack Pledger, Paturu Kondaiah

https://doi.org/10.18632/aging.204372pp 8645—8660

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Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging

Tanima SenGupta, Yohan Lefol, Lisa Lirussi, Veronica Suaste, Torben Luders, Swapnil Gupta, Yahyah Aman, Kulbhushan Sharma, Evandro Fei Fang, Hilde Nilsen

https://doi.org/10.18632/aging.204375pp 8661—8687

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Efficacy of zinc carnosine in the treatment of colorectal cancer and its potential in combination with immunotherapy in vivo

Weiwei Tang, Hanyuan Liu, Xiao Li, Theng Choon Ooi, Nor Fadilah Rajab, Hongyong Cao, Razinah Sharif

https://doi.org/10.18632/aging.204380pp 8688—8699

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Identification and validation of a glycolysis-related gene signature for depicting clinical characteristics and its relationship with tumor immunity in patients with colon cancer

Gang Liu, Xiaoyang Wu, Jian Chen

https://doi.org/10.18632/aging.204226pp 8700—8718

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Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants

Yanyan Ling, Chuan Jiang, Zhenzhen Xiao, Xiao Shang, Qi Li, Baojie Wang, Maolin Hao, Fei Liu, Nannan Zhao, Jianli Feng, Hongqin Zhao

https://doi.org/10.18632/aging.204338pp 8719—8728

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Deep remission from induction chemotherapy predicts favorable long-term survivals in early stage extranodal nasal NK/T-cell lymphoma receiving sequential chemotherapy and radiation

Fei Qi, Wenyuan Zhou, Yan Xie, Yan Sun, Meng Wu, Yue Chai, Bo Chen, Ningjing Lin, Weiping Liu, Ning Ding, Yexiong Li, Mei Dong, Yuqin Song, Jun Zhu

https://doi.org/10.18632/aging.204355pp 8729—8744

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Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation in vitro and in vivo

Yuan Li, Haifeng Zhang, Weihong Long, Menghan Gao, Weiying Guo, Lu Yu

https://doi.org/10.18632/aging.204363pp 8745—8762

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HBP1 inhibits the development of type 2 diabetes mellitus through transcriptional activation of the IGFBP1 gene

Yuning Cheng, Ruixiang Yang, Yue Zhou, Jiyin Wang, Tongjia Zhang, Shujie Wang, Hui Li, Wei Jiang, Xiaowei Zhang

https://doi.org/10.18632/aging.204364pp 8763—8782

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Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma

Shaoyan Zheng, Botao Pan

https://doi.org/10.18632/aging.204369pp 8783—8804

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Desmocollin-2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma via the ERK/c-MYC signaling pathway

Bo He, Li Guo, Youwen Hu, Hongyan Huang, Lijun Wan, Kedong Xu, Fenfen Wang, Zhili Wen

https://doi.org/10.18632/aging.204370pp 8805—8817

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Prognostic and clinicopathological value of m6A regulators in human cancers: a meta-analysis

Zhangci Su, Leyao Xu, Xinning Dai, Mengyao Zhu, Xiaodan Chen, Yuanyuan Li, Jie Li, Ruihan Ge, Bin Cheng, Yun Wang

https://doi.org/10.18632/aging.204371pp 8818—8838

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lncRNA HHIP-AS1/HHIP modulates osteogenic differentiation of BM-MSCs by regulating Hedgehog signaling pathway

Xin-Hua Yin, Xiao-Yuan Wang, Shi-Chang Liu, Liang Yan, Bao-Rong He, Ding-Jun Hao, Ming Yang, Zhong-Kai Liu

https://doi.org/10.18632/aging.204381pp 8839—8855

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Polydatin administration attenuates the severe sublesional bone loss in mice with chronic spinal cord injury

Jiheng Zhan, Dan Luo, Bingde Zhao, Shudong Chen, Jiyao Luan, Junhua Luo, Yu Hou, Yonghui Hou, Wenke Xu, Wanying Yan, Ji Qi, Xing Li, Qing Zhang, Dingkun Lin

https://doi.org/10.18632/aging.204382pp 8856—8875

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Corrections

Correction for: CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma

Dan Zi, Qing Li, Cheng-xiong Xu, Zhi-Wei Zhou, Guan-Bin Song, Cheng-Bin Hu, Fang Wen, Han-Lin Yang, Lei Nie, Xing Zhao, Jun Tan, Shu-Feng Zhou, Zhi-Xu He

https://doi.org/10.18632/aging.204367pp 8876—8878

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Correction for: Nicotine exposure impairs germ cell development in human fetal ovaries cultured in vitro

Shun-Feng Cheng, Xun-Si Qin, Ze-Li Han, Xiao-Feng Sun, Yan-Ni Feng, Fan Yang, Wei Ge, Lan Li, Yong Zhao, Massimo De Felici, Shu-Hua Zou, Yi Zhou, Wei Shen

https://doi.org/10.18632/aging.204392pp 8879—8881

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