Advance Online Publications

Table of Contents

Editorials

Aging, cardiorespiratory fitness and sympathetic transduction

Myles W. O’Brien, Said Mekary, Derek S. Kimmerly,

https://doi.org/10.18632/aging.204091

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Molecular markers associated with cognitive impairment in centenarians

Tinna Stevnsner, Ines Sanchez-Roman,

https://doi.org/10.18632/aging.204094

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Epigenetics-based treatment strategies for Alzheimer’s disease

Qing Cao, Wei Wang, Zhen Yan,

https://doi.org/10.18632/aging.204096

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Priority Research Paper

Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism

Thorsten R. Doeppner, Cristin Coman, Daiana Burdusel, Diana-Larisa Ancuta, Ulf Brockmeier, Daniel Nicolae Pirici, Kuang Yaoyun, Dirk M. Hermann, Aurel Popa-Wagner,

https://doi.org/10.18632/aging.204069

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Research Papers

COVID-19
The roles of inactivated vaccines in older patients with infection of Delta variant in Nanjing, China

Xiao-Chun Song, Xue-Hui Zhou, Jing-Hui Cheng, Wen-Hao Zhang, Xiao Shen, Huan Xu, Shuai Nie, Ji-Lai Xiao, Fang Sun, Chang Shu, Jiu-Dong Chen, Yan Tang, Xiang Wang, Xin-Pei Sun, Jia-Kui Sun, Ping Feng, Qian-Kun Shi,

https://doi.org/10.18632/aging.204085

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Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence

Ryan Wallis, Deborah Milligan, Bethany Hughes, Hannah Mizen, José Alberto López-Domínguez, Ugochim Eduputa, Eleanor J. Tyler, Manuel Serrano, Cleo L. Bishop,

https://doi.org/10.18632/aging.204072

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Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)

Sonali Nashine, Pinchas Cohen, Junxiang Wan, M. Cristina Kenney,

https://doi.org/10.18632/aging.204074

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Identification of combined biomarkers for predicting the risk of osteoporosis using machine learning

Zhenlong Zheng, Xianglan Zhang, Bong-Kyeong Oh, Ki-Yeol Kim,

https://doi.org/10.18632/aging.204084

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MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models

Wei Zhang, Yuewang Yang, Zifei Xiang, Jinping Cheng, Zhijun Yu, Wen Wang, Ling Hu, Fuyun Ma, Youping Deng, Zhigang Jin, Xiamin Hu,

https://doi.org/10.18632/aging.203883

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Sperm DNA integrity is critically impacted by male age but does not influence outcomes of artificial insemination by husband in the Chinese infertile couples

Yumei Luo, Shunhong Wu, Mimi Zhang, Hua Zhou, Jingru Yuan, Yiying Yang, Yufang Zhong, Qing Li, Xiaofang Sun, Xia Xu, Detu Zhu,

https://doi.org/10.18632/aging.204058

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Glioblastoma: two immune subtypes under the surface of the cold tumor

Wu Xiong, Cong Li, Guang Kong, Bowen Wan, Siming Wang, Jin Fan,

https://doi.org/10.18632/aging.204067

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CircRNA has_circ_0069313 induced OSCC immunity escape by miR-325-3p-Foxp3 axes in both OSCC cells and Treg cells

Yiyang Chen, Zeyu Li, Jianfeng Liang, Jiayu Liu, Jiansuo Hao, Quan Wan, Jiameng Liu, Chongdai Luo, Zhiyuan Lu,

https://doi.org/10.18632/aging.204068

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Exercise intervention prevents early aged hypertension-caused cardiac dysfunction through inhibition of cardiac fibrosis

Yi Hong, Ai-Lun Yang, James K.S. Wong, Kunanya Masodsai, Shin-Da Lee, Yi-Yuan Lin,

https://doi.org/10.18632/aging.204077

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Intra-tumoral angiogenesis correlates with immune features and prognosis in glioma

Qing Zhang, Yao-Xing Guo, Wan-Lin Zhang, Hai-Yan Lian, Natasha Iranzad, Endi Wang, Ying-Chun Li, Hai-Chao Tong, Le-Yao Li, Ling-Yun Dong, Lian-He Yang, Shuang Ma,

https://doi.org/10.18632/aging.204079

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Transcriptional ITPR3 as potential targets and biomarkers for human pancreatic cancer

Wangyang Zheng, Xue Bai, Yongxu Zhou, Liang Yu, Daolin Ji, Yuling Zheng, Nanfeng Meng, Hang Wang, Ziyue Huang, Wangming Chen, Judy Wai Ping Yam, Yi Xu, Yunfu Cui,

https://doi.org/10.18632/aging.204080

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A real-time pluripotency reporter for the long-term and real-time monitoring of pluripotency changes in induced pluripotent stem cells

Hong-Fen Shen, Yong-Long Li, Shi-Hao Huang, Jia-Wei Xia, Zhi-Fang Yao, Gao-Fang Xiao, Ying Zhou, Ying-Chun Li, Jun-Wen Shi, Xiao-Lin Lin, Wen-Tao Zhao, Yan Sun, Yu-Guang Tian, Jun-Shuang Jia, Dong Xiao,

https://doi.org/10.18632/aging.204083

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Are beta blockers effective in preventing stroke associated infections? - a systematic review and meta-analysis

Li Yang, Xiang Wenping, Zhang Jinfeng, Pang Jiangxia, Wang Jingbo, Wang Baojun,

https://doi.org/10.18632/aging.204086

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NcRNAs-mediated P2RX1 expression correlates with clinical outcomes and immune infiltration in patients with breast invasive carcinoma

Yiyue Xu, Bing Zou, Bingjie Fan, Butuo Li, Jinming Yu, Linlin Wang, Jin Zhang,

https://doi.org/10.18632/aging.204087

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Long noncoding RNA KCNQ1OT1 inhibits osteoclast differentiation by regulating the miR-128-3p/NFAT5 axis

Hengshuo Zhang, Lu Chen, Ziyu Wang, Zhenqian Sun, Yu Shan, Qinghui Li, Linzeng Qi, Hongliang Wang, Yunzhen Chen,

https://doi.org/10.18632/aging.204088

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Local anesthetic levobupivacaine induces ferroptosis and inhibits progression by up-regulating p53 in non-small cell lung cancer

Minghua Meng, Meiling Huang, Cuicui Liu, Jiming Wang, Weihua Ren, Shaomin Cui, Jianhua Gu, Jinlan Xie, Bin Ma, Guangzhu Yang, Shuncheng He,

https://doi.org/10.18632/aging.203138

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Identification of an immune subtype predicting survival risk and immune activity in hepatocellular carcinoma

Feng Zhao, Nuo Xu, Jiali Yang, Bo Li, Jianwei Shi, Yuanyuan Zheng, Longjin Xu,

https://doi.org/10.18632/aging.202953

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Exosome-derived long non-coding RNA ZFAS1 controls cardiac fibrosis in chronic kidney disease

Yunfei Wang, Xufen Cao, Liqiu Yan, Ye Zheng, Jing Yu, Fuyun Sun, Zheng Lian, Lina Sun,

https://doi.org/10.18632/aging.202599

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Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury in vitro and in vivo

Bojing Yan, Lixin Gao, Yingxiang Huang, Xiaolei Wang, Xuqiang Lang, Fancheng Yan, Bo Meng, Xiaowei Sun, Genlin Li, Yanling Wang,

https://doi.org/10.18632/aging.202245

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Targeting LncRNA EPIC1 to inhibit human colon cancer cell progression

Qiong Wu, Jue Wei, Chen Zhao, Shihao Xiang, Min Shi, Yugang Wang,

https://doi.org/10.18632/aging.103790

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Combined impacts of histamine receptor H1 gene polymorphisms and an environmental carcinogen on the susceptibility to and progression of oral squamous cell carcinoma

Yi-Fang Ding, Yung-Wei Lin, Wen-Kuan Chiu, Chiao-Wen Lin, Yi-Chieh Yang, Lun-Ching Chang, Jungshan Chang, Shun-Fa Yang, Ming-Hsien Chien,

https://doi.org/10.18632/aging.204089

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