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• Research PaperVolume 17, Issue 6pp 1429-1451

  Spermidine supplementation and protein restriction protect from organismal and brain aging independently

  Relevance score: 0.00

  YongTian Liang, Anja Krivograd, Sebastian J. Hofer, Laxmikanth Kollipara, Thomas Züllig, Albert Sickmann, Tobias Eisenberg, Stephan J. Sigrist

  Keywords: aging, brain aging, spermidine, protein restriction, mitochondria

  Published in Aging on June 7, 2025

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• Research PaperVolume 12, Issue 17pp 16852-16866

  Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans

  Relevance score: 0.00

  Xin Yang, Mohan Zhang, Yuhua Dai, Yuchao Sun, Yahyah Aman, Yuying Xu, Peilin Yu, Yifan Zheng, Jun Yang, Xinqiang Zhu

  Keywords: spermidine, neurodegenerative diseases, caenorhabditis elegans, mitophagy, aging

  Published in Aging on September 9, 2020

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• Research PaperVolume 12, Issue 1pp 650-671

  Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function

  Relevance score: 0.00

  Junying Wang, Shaoqi Li, Ju Wang, Feixiang Wu, Yuhan Chen, Hao Zhang, Yubo Guo, Yan Lin, Lingxu Li, Xue Yu, Ting Liu, Yajun Zhao

  Keywords: spermidine, polyamine metabolism, SIRT1, PGC-1α, mitochondrial biogenesis

  Published in Aging on January 6, 2020

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• Priority Research PaperVolume 11, Issue 14pp 4783-4800

  The metabolomic signature of extreme longevity: naked mole rats versus mice

  Relevance score: 0.00

  Mélanie Viltard, Sylvère Durand, Maria Pérez-Lanzón, Fanny Aprahamian, Deborah Lefevre, Christine Leroy, Frank Madeo, Guido Kroemer, Gérard Friedlander

  Keywords: spermidine, antioxidants, autophagy, catabolism, meta-organism, microbiota

  Published in Aging on July 24, 2019

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• Research PaperVolume 12, Issue 13pp 13716-13739

  Spermine and spermidine modulate T-cell function in older adults with and without cognitive decline ex vivo

  Relevance score: 0.00

  Maximilian Fischer, Johanna Ruhnau, Juliane Schulze, Daniela Obst, Agnes Flöel, Antje Vogelgesang

  Keywords: dementia, spermine, spermidine, T cell, cytokines

  Published in Aging on June 30, 2020

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• Research PaperVolume 10, Issue 1pp 19-33

  Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline

  Relevance score: 0.00

  Claudia Schwarz, Slaven Stekovic, Miranka Wirth, Gloria Benson, Philipp Royer, Stephan J Sigrist, Thomas Pieber, Christopher Dammbrueck, Christoph Magnes, Tobias Eisenberg, Tobias Pendl, Jens Bohlken, Theresa Köbe, Frank Madeo, Agnes Flöel

  Keywords: polyamines, dietary supplement, spermidine, safety, subjective cognitive decline, aging

  Published in Aging on January 8, 2018

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• Research PaperVolume 12, Issue 20pp 20212-20225

  LINC00265 targets miR-382-5p to regulate SAT1, VAV3 and angiogenesis in osteosarcoma

  Relevance score: 0.00

  Ying Xiao, Chunling Li, Hongyue Wang, Yijun Liu

  Keywords: angiogenesis, vasculogenic mimicry, LINC00265, miR-382-5p, spermidine/spermine N1-acetyltransferase-1

  Published in Aging on August 14, 2020

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• RetractionVolume 17, Issue 1pp 278-279

  Retraction of: LINC00265 targets miR-382-5p to regulate SAT1, VAV3 and angiogenesis in osteosarcoma

  Relevance score: 0.00

  Ying Xiao, Chunling Li, Hongyue Wang, Yijun Liu

  Keywords: angiogenesis, vasculogenic mimicry, LINC00265, miR-382-5p, spermidine/spermine N1-acetyltransferase-1