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• CommentaryVolume 14, Issue 5pp 2020-2024

  As predicted by hyperfunction theory, rapamycin treatment during development extends lifespan

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: quasi-programmed aging, mTOR, sirolimus, growth, reprogramming

  Published in Aging on March 5, 2022

• Research PaperVolume 8, Issue 12pp 3535-3551

  Gerosuppression by pan-mTOR inhibitors

  Relevance score: 0.00

  Olga V. Leontieva, Mikhail V. Blagosklonny

  Keywords: dual mTORC1/C2 inhibitors, rapalogs, sirolimus, aging, cancer, senescence

  Published in Aging on December 30, 2016

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• Research PerspectiveVolume 6, Issue 12pp 1010-1018

  Gerosuppression in confluent cells

  Relevance score: 0.00

  Olga V. Leontieva, Mikhail V. Blagosklonny

  Keywords: MTOR, rapalogs, sirolimus, aging, cancer, senescence

  Published in Aging on December 31, 2014

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• Research PerspectiveVolume 14, Issue 20pp 8140-8149

  Rapamycin treatment early in life reprograms aging: hyperfunction theory and clinical practice

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: senescence, gerostatics, geroscience, sirolimus, healthspan

  Published in Aging on October 24, 2022

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• Research PerspectiveVolume 12, Issue 8pp 6492-6510

  Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections

  Relevance score: 0.00

  Alex Zhavoronkov

  Keywords: COVID-19, SARS-CoV-2, coronavirus, sirolimus, rapalog

  Published in Aging on March 31, 2020

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• Research PaperVolume 7, Issue 11pp 964-973

  Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)

  Relevance score: 0.00

  Corinna Ross, Adam Salmon, Randy Strong, Elizabeth Fernandez, Marty Javors, Arlan Richardson, Suzette Tardif

  Keywords: nonhuman primate, antiaging, longevity, healthspan, animal models, sirolimus

  Published in Aging on November 13, 2015

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• Research PaperVolume 7, Issue 11pp 911-927

  A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition

  Relevance score: 0.00

  Clemens Stockklausner, Simon Raffel, Julia Klermund, Obul Reddy Bandapalli, Fabian Beier, Tim H. Brümmendorf, Friederike Bürger, Sven W. Sauer, Georg F. Hoffmann, Holger Lorenz, Laura Tagliaferri, Daniel Nowak, Wolf-Karsten Hofmann, Rebecca Buergermeister, Carolin Kerber, Tobias Rausch, Jan O. Korbel, Brian Luke, Andreas Trumpp, Andreas E. Kulozik

  Keywords: TERT, TERC, mTOR, rapamycin, sirolimus, senescence

  Published in Aging on November 6, 2015

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• ReviewVolume 5, Issue 11pp 793-801

  Immunostimulatory activity of lifespan-extending agents

  Relevance score: 0.00

  José Manuel Bravo-San Pedro, Laura Senovilla

  Keywords: ATG5, everolimus, mTOR, sirolimus, tacrolimus, temsirolimus

  Published in Aging on December 5, 2013

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