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• EditorialVolume 8, Issue 4pp 567-568

  Repurposing of FDA-approved drugs against cancer – focus on metastasis

  Relevance score: 0.00

  Béla Ozsvári, Rebecca Lamb, Michael P. Lisanti

  Keywords: tumor metastasis, repurposing, antibiotics, aspirin

  Published in Aging on April 2, 2016

• Research PaperVolume 10, Issue 11pp 3294-3307

  Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts

  Relevance score: 0.00

  Bela Ozsvari, John R. Nuttall, Federica Sotgia, Michael P. Lisanti

  Keywords: drug repurposing, aging, senescence, senolytic drugs, antibiotics, azithromycin, roxithromycin

  Published in Aging on November 14, 2018

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• Research PaperVolume 15, Issue 11pp 5144-5163

  Network medicine framework identified drug-repurposing opportunities of pharmaco-active compounds of Angelica acutiloba (Siebold & Zucc.) Kitag. for skin aging

  Relevance score: 0.00

  Jiaxin Mo, Zunjiang Li, Hankun Chen, Zhongyu Lu, Banghan Ding, Xiaohong Yuan, Yuan Liu, Wei Zhu

  Keywords: network medicine framework, drug-repurposing opportunities, Angelica acutiloba (Siebold & Zucc.) Kitag., skin aging, pharmaco-active compounds

  Published in Aging on June 12, 2023

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• Research PaperVolume 12, Issue 19pp 19022-19044

  Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease

  Relevance score: 0.00

  Pei Ma, Lifeng Yue, Sen Zhang, Dacheng Hao, Zhihong Wu, Lijia Xu, Guanhua Du, Peigen Xiao

  Keywords: neuroblastoma, drug repurposing, gene expression, the connectivity map, L1000 FWD

  Published in Aging on October 12, 2020

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• Research PaperVolume 17, Issue 11pp 2844-2858

  REVIVE: a computational platform for systematically identifying rejuvenating chemical and genetic perturbations

  Relevance score: 0.00

  Sascha Jung, Javier Arcos Hodar, Tejwasi Venkata S. Badam, Antonio del Sol

  Keywords: computational modeling, machine learning, aging, rejuvenation, drug repurposing

  Published in Aging on November 25, 2025

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• Research PaperVolume 13, Issue 13pp 17407-17427

  Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways

  Relevance score: 0.00

  Linjuan Huang, Ling Zhao, Jing Zhang, Fang He, Hao Wang, Qing Liu, Deyao Shi, Na Ni, William Wagstaff, Connie Chen, Russell R. Reid, Rex C. Haydon, Hue H. Luu, Le Shen, Tong-Chuan He, Liangdan Tang

  Keywords: ovarian cancer, cisplatin, chemoresistance, cisplatin resistance, mebendazole (MBZ), drug repurposing

  Published in Aging on July 7, 2021

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• Research PerspectiveVolume 12, Issue 8pp 6511-6517

  COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

  Relevance score: 0.00

  Camillo Sargiacomo, Federica Sotgia, Michael P. Lisanti

  Keywords: COVID-19, corona virus, aging, senescence, senolytic drug therapy, prevention, viral replication, drug repurposing, antibiotic, Azithromycin, Hydroxy-chloroquine, Rapamycin, Doxycycline, Quercetin

  Published in Aging on March 30, 2020

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• Research PaperVolume 8, Issue 9pp 2127-2152

  In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state

  Relevance score: 0.00

  Alexander Aliper, Aleksey V. Belikov, Andrew Garazha, Leslie Jellen, Artem Artemov, Maria Suntsova, Alena Ivanova, Larisa Venkova, Nicolas Borisov, Anton Buzdin, Polina Mamoshina, Evgeny Putin, Andrew G. Swick, Alexey Moskalev, Alex Zhavoronkov

  Keywords: geroprotector, drug discovery, screening, drug repurposing, aging

  Published in Aging on September 24, 2016

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• Research PaperVolume 8, Issue 8pp 1593-1606

  Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)

  Relevance score: 0.00

  Marco Fiorillo, Rebecca Lamb, Herbert B. B. Tanowitz, Anna Rita Rita Cappello, Ubaldo E. E. Martinez-Outschoorn, Federica Sotgia, Michael P. P. Lisanti

  Keywords: bedaquiline, mitochondria, tumor-initiating cells (TICs), cancer stem-like cells (CSCs), drug repurposing

  Published in Aging on June 22, 2016

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