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• Research PaperVolume 12, Issue 21pp 21391-21403

  Aging-related changes in the gene expression profile of human lungs

  Relevance score: 0.00

  Ina Jeong, Jae-Hyun Lim, Jin-Soo Park, Yeon-Mok Oh

  Keywords: lung, aging, gene analysis, RNA-seq, transcriptome

  Published in Aging on November 9, 2020

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• Research PaperVolume 12, Issue 13pp 12534-12581

  Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids

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  Steffen Möller, Nadine Saul, Alan A. Cohen, Rüdiger Köhling, Sina Sender, Hugo Murua Escobar, Christian Junghanss, Francesca Cirulli, Alessandra Berry, Peter Antal, Priit Adler, Jaak Vilo, Michele Boiani, Ludger Jansen, Dirk Repsilber, Hans Jörgen Grabe, Stephan Struckmann, Israel Barrantes, Mohamed Hamed, Brecht Wouters, Liliane Schoofs, Walter Luyten, Georg Fuellen

  Keywords: gene expression analysis, network biology analysis

  Published in Aging on July 7, 2020

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• Research PaperVolume 13, Issue 6pp 8306-8319

  Identification of key genes in coronary artery disease: an integrative approach based on weighted gene co-expression network analysis and their correlation with immune infiltration

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  Yang Yang, Xiangshan Xu

  Keywords: weighted gene co-expression network analysis, least absolute shrinkage and selection operator, immune cell infiltration, coronary artery disease

  Published in Aging on March 3, 2021

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• Research PaperVolume 12, Issue 7pp 5812-5831

  Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis

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  Qiqing Huang, Yan Chen, Shaoran Shen, Yuanyuan Wang, Liya Liu, Shuangshuang Wu, Wei Xu, Weihong Zhao, Mingyan Lin, Jianqing Wu

  Keywords: idiopathic pulmonary fibrosis (IPF), klotho (KL), weighted gene co-expression network analysis (WGCNA), precision-cut lung slices (PCLSs), pulmonary fibroblasts

  Published in Aging on April 3, 2020

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• Research PaperVolume 11, Issue 21pp 9478-9491

  Identifying hub genes of clear cell renal cell carcinoma associated with the proportion of regulatory T cells by weighted gene co-expression network analysis

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  Ye-Hui Chen, Shao-Hao Chen, Jian Hou, Zhi-Bin Ke, Yu-Peng Wu, Ting-Ting Lin, Yong Wei, Xue-Yi Xue, Qing-Shui Zheng, Jin-Bei Huang, Ning Xu

  Keywords: ccRCC, weighted gene co-expression network analysis, Treg cells, hub genes, anti-tumor immune

  Published in Aging on October 31, 2019

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• Research PaperVolume 10, Issue 12pp 4024-4041

  SNCA overexpression disturbs hippocampal gene expression trajectories in midlife

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  Thomas Hentrich, Zinah Wassouf, Olaf Riess, Julia M. Schulze-Hentrich

  Keywords: alpha-synuclein, Parkinson’s disease, age, midlife, gene-environment interaction, gene expression analysis, systems biology

  Published in Aging on December 13, 2018

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• Research PaperVolume 13, Issue 9pp 12733-12747

  Identification of key pathways and genes in carotid atherosclerosis through bioinformatics analysis of RNA-seq data

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  Zhongchen Li, Jiheng Hao, Kun Chen, Qunlong Jiang, Peijian Wang, Xiaohui Xing, Jiyue Wang, Yinjiang Zhang, Yilei Xiao, Liyong Zhang

  Keywords: carotid atherosclerosis, RNA-seq, enrichment analysis, hub gene, bioinformatics analysis

  Published in Aging on May 11, 2021

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• Research PaperVolume 13, Issue 4pp 5120-5135

  Identification of hub genes and key pathways in the emphysema phenotype of COPD

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  Qiunan Zuo, Youyu Wang, Deqing Yang, Shujin Guo, Xiaohui Li, Jiajia Dong, Chun Wan, Yongchun Shen, Fuqiang Wen

  Keywords: chronic obstructive pulmonary disease, emphysema, weighted gene co-expression network analysis

  Published in Aging on February 1, 2021

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• Research PaperVolume 16, Issue 8pp 6673-6693

  Senescent characteristics of human corneal endothelial cells upon ultraviolet-A exposure

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  Kohsaku Numa, Sandip Kumar Patel, Zhixin A. Zhang, Jordan B. Burton, Akifumi Matsumoto, Jun-Wei B. Hughes, Chie Sotozono, Birgit Schilling, Pierre-Yves Desprez, Judith Campisi, Koji Kitazawa

  Keywords: cellular senescence, senescence-associated secretory phenotype, RNA-Seq, proteomics, gene ontology analysis

  Published in Aging on April 26, 2024

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• Research PaperVolume 12, Issue 4pp 3486-3501

  Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of osteosarcoma

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  Chi Zhang, Jing-Hui Zheng, Zong-Han Lin, Hao-Yuan Lv, Zhuo-Miao Ye, Yue-Ping Chen, Xiao-Yun Zhang

  Keywords: bioinformatics analysis, TCGA, gene set enrichment analysis, prognosis, biomarker

  Published in Aging on February 9, 2020

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• Research PaperVolume 13, Issue 5pp 7259-7283

  Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

  Relevance score: 0.00

  Zhefan Stephen Chen, Xiao Lin, Ting-Fung Chan, Ho Yin Edwin Chan

  Keywords: planar cell polarity, pan-cancer analysis, gene set enrichment analysis, DNA methylation, genomic alteration

  Published in Aging on February 26, 2021

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• Research PaperVolume 11, Issue 16pp 6469-6489

  Identification and validation of four hub genes involved in the plaque deterioration of atherosclerosis

  Relevance score: 0.00

  Peipei Chen, Yuexin Chen, Wei Wu, Lianfeng Chen, Xufei Yang, Shuyang Zhang

  Keywords: mRNA, robust rank aggregation approach, gene set enrichment analysis, atherosclerosis, biomarker

  Published in Aging on August 26, 2019

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• Research PaperVolume 16, Issue 3pp 2123-2140

  Identification of renal ischemia reperfusion injury-characteristic genes, pathways and immunological micro-environment features through bioinformatics approaches

  Relevance score: 0.00

  Xinghua Lv, Qian Fan, Xuanjie Li, Peng Li, Zhanhai Wan, Xuena Han, Hao Wang, Xiaoxia Wang, Lin Wu, Bin Huo, Li Yang, Gen Chen, Yan Zhang

  Keywords: ischemia reperfusion injury, gene set variation analysis, weighted gene coexpression network analysis, MiRNAs, macrophage

  Published in Aging on February 6, 2024

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• Research PaperVolume 15, Issue 15pp 7760-7780

  MYEF2: an immune infiltration-related prognostic factor in IDH-wild-type glioblastoma

  Relevance score: 0.00

  Yunxiao Zhang, Yunyu Wen, Jing Nie, Tong Wang, Gang Wang, Qiaoping Gao, Yongfu Cao, Hai Wang, Songtao Qi, Sidi Xie

  Keywords: MYEF2, weighted gene co-expression network analysis (WGCNA), immune infiltration, RNA binding proteins (RBPs), glioblastoma

  Published in Aging on August 8, 2023

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• Research PaperVolume 12, Issue 24pp 25828-25844

  A glycolysis-related gene signature predicts prognosis of patients with esophageal adenocarcinoma

  Relevance score: 0.00

  Huafeng Kang, Nan Wang, Xuan Wang, Yu Zhang, Shuai Lin, Guochao Mao, Di Liu, Chengxue Dang, Zhangjian Zhou

  Keywords: esophageal adenocarcinoma, glycolysis, gene signature, prognosis, gene set enrichment analysis

  Published in Aging on November 25, 2020

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• Research PaperVolume 12, Issue 4pp 3694-3712

  Identification of biomarkers related to CD8⁺ T cell infiltration with gene co-expression network in clear cell renal cell carcinoma

  Relevance score: 0.00

  Jiaxing Lin, Meng Yu, Xiao Xu, Yutao Wang, Haotian Xing, Jun An, Jieping Yang, Chaozhi Tang, Dan Sun, Yuyan Zhu

  Keywords: clear cell renal cell carcinoma (ccRCC), CIBERSORT, weighted gene co-expression network analysis (WGCNA), CD8+ T cells, CCL5

  Published in Aging on February 20, 2020

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• Research PaperVolume 11, Issue 13pp 4736-4756

  Identification of hub genes in prostate cancer using robust rank aggregation and weighted gene co-expression network analysis

  Relevance score: 0.00

  Zhen-yu Song, Fan Chao, Zhiyuan Zhuo, Zhe Ma, Wenzhi Li, Gang Chen

  Keywords: prostate cancer, hub genes, robust rank aggregation, weighted gene co-expression network analysis, bioinformatics

  Published in Aging on July 15, 2019

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• Research PaperVolume 16, Issue 2pp 1111-1127

  AMIGO2 is a pivotal therapeutic target related to M2 polarization of macrophages in pancreatic ductal adenocarcinoma

  Relevance score: 0.00

  Shensi Chen, Wujun Du, Ke Feng, Ke Liu, Cunji Li, Shengming Li, Hua Yin

  Keywords: pancreatic cancer, M2 polarization, gene set enrichment analysis, machine learning, AMIGO2

  Published in Aging on January 5, 2024

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• Research PaperVolume 13, Issue 3pp 3819-3842

  Four hub genes regulate tumor infiltration by immune cells, antitumor immunity in the tumor microenvironment, and survival outcomes in lung squamous cell carcinoma patients

  Relevance score: 0.00

  Tuo Zhang, Haitang Yang, Beibei Sun, Feng Yao

  Keywords: immunity, lung squamous carcinoma, single sample gene set enrichment analysis, robust rank aggregations, CIBERSORT

  Published in Aging on January 10, 2021

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• Research PaperVolume 13, Issue 12pp 16485-16499

  Cell landscape atlas for patients with chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy constructed using single-cell RNA sequencing

  Relevance score: 0.00

  Ran Miao, Xingbei Dong, Juanni Gong, Yidan Li, Xiaojuan Guo, Jianfeng Wang, Qiang Huang, Ying Wang, Jifeng Li, Suqiao Yang, Tuguang Kuang, Jun Wan, Min Liu, Zhenguo Zhai, Jiuchang Zhong, Yuanhua Yang

  Keywords: chronic thromboembolic pulmonary hypertension, single-cell RNA sequencing, gene ontology enrichment analysis

  Published in Aging on June 21, 2021

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